All, I am in the process of trying to decipher which of the following would be most beneficial to realize the increased protein synthesis effects of ecdy:
1) ecdysterone
2) 20-beta-hydroxyecdysterone
3) Rhaponticum carthamoides
Based on initial research, it appears that taking Rhaponticum carthamoides whole extract is superior to that of individual ecdysterones.
Has anyone tried the 95% Rhaponticum carthamoides powder? How about Ecdypure? Please read the information posted below, unless you are already familiar, and discuss...
The following on-topic excerpt was taken from:
http://www.rhodiolarosea.org/Web-Rhaponticum.pdf
Here is another excellent article entitled:Introduction: Rhaponticum carthamoides (Willd) Ijin, also know as Leuzea, or Maral root, is plant indigenous to the Lake Baikal region and distributed throughout Eastern Siberia. Traditionally the Siberians consumed the Leuzea tea mixed with Rhodiola rosea root for a long time as a natural stimulant, in cases of tiredness and general weakness after illness and energizing remedy after the long Siberian winter...
Phytochemistry: Key active constituents responsible for specific anabolic effect of Rhaponticum carthamoides is a mixture of compounds called, "levseins". Levseins represents a complex of more than 10 ecdysterones including 20-beta-ecdysterone, makisterone C, 24-dehydromakisterone A, carthamosterone, polypodyne B and ajugasterone C.
Pharmacology: According to Russian researchers the Leuzea extract stimulates muscle protein synthesis by increasing the activity of the polyribosomes. Polyribosomes are the cellular compartments where the actual protein synthesis takes place. Researchers extracted and purified various ecdysteroids from Leuzea and found that the ecdysteroids increased the mass of the developing quails in a dose-dependent manner, with the rate of increase proportional to the ecdysteroids content. It was evident that the plethora of growth-promoting, vitamin-like effects induced by Leuzea is mediated by ecdysteroids.
However it is important to point out that the mixture of ecdysterones was found to be responsible for enhancement of muscle protein synthesis. The research indicated that the whole extract of Rhaponticum carthamoides containing mixture of levseins possess much superior physiological activity compared with the activity of purified individual constituents (Seifulla 1999). Results indicated that 0.5mg/kg body weight is the optimal dosage of 20-beta-ecdysterone in any sport and performance formula.
Rhaponticum carthamoides - A Powerful Natural Anabolic Back in the '70s, the Soviet sports teams were caught using numerous steroids. In 1976 Soviet scientists discovered two substances that had traditional historical use behind them. One was a plant called Rhaponticum carthamoides, the active ingredient of which is called beta-ecdysterone. The Soviets manufactured a synthetic version of this powerful substance for their athletes with great success. Soon after, the U.S. version called Mesobolin circulated on the underground market for a long time. In back-to-back studies with animals, the Rhaponticum extract was actually superior to synthetic steroids like Dianabol at inducing endurance and muscle cell growth (Syrov et al. 1976, 1992).
The examination of the difference in action between beta-ecdysterone and synthetic steroids revealed that the latter go directly to the nucleus of a cell to tell the blueprint, the DNA, to produce more RNA. Then the RNA tells the ribosome to produce more protein. Beta-ecdysterone, on the other hand, goes directly to the ribosome and increases what is called translation, the rate at which new protein is being made (Syrov et al. 1984)...
Phytoecdysteroids:
http://www.rrreading.com/ecdysteroids_rklein.pdf
Here is a chart taken from the above article:
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06-13-2006, 12:10 PM #1
Ecdysterone, 20-beta-hydroxyecdysterone or Rhaponticum Carthamoides Extract?
Last edited by HalleluYAH; 06-13-2006 at 12:17 PM.
Psalms 51:10-13
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06-13-2006, 12:11 PM #2
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06-13-2006, 12:13 PM #3
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06-13-2006, 12:15 PM #4Originally Posted by HalleluYAH
Carry on.Sinners in the hands of an angry Mod.
Mod is a concept...by which, we measure, our pain.
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06-13-2006, 12:20 PM #5
Here is another excerpt from the article listed above:
Toxicity: From more than 80 species of plants containing phyto-ecdysterones only Leuzea extract was shown very safe for humans at even high dosages. The extract did not produce mortality after administration of very large doses (up to 4 g/kg). After administration of relatively high doses above 10 g/kg, there occurred some functional changes in CNS, manifested by weakening of some reflexes, a decrease in muscle tone, an increase of the narcotic effects of chloral hydrate and a tendency towards impaired learning and memory. [color=red][/b]It is always a good idea to remember that taking “more is not always good” for you.[color][/b]Psalms 51:10-13
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06-13-2006, 12:23 PM #6Originally Posted by HalleluYAH
i did have very positive results from the stack it was included in though.- SNS Rep
- http://www.bodybuilding.com/store/sns/sns.htm
- Beer20 @ seriousnutritionsolutions.com
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06-13-2006, 12:23 PM #7Originally Posted by HalleluYAHwww.placebro.net
This is a bandit's life, it comes and goes and thems the breaks.
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06-13-2006, 12:24 PM #8
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06-13-2006, 12:24 PM #9Originally Posted by nni
Perhaps I should copy abnd paste this to Danes thread here?
http://forum.bodybuilding.com/showthread.php?t=770406
Search function was not working when I started this thread???Psalms 51:10-13
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06-13-2006, 12:27 PM #10
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06-13-2006, 12:30 PM #11
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06-13-2006, 12:32 PM #12
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06-13-2006, 12:32 PM #13
ecdysterone = 20-beta-hydroxyecdysterone
i believe kingdomCome bought some bulk rhaponcticum powder and is going to be dosing it at 20 grams a day (the only way he can get a decent amount of actives) and i'm looking forward to his results. it should be pretty good, but the annoyance of having to take 20 grams a day probably isn't worth it. ecdysterone is effective (and probably the most cost effective) but there are other ecdysteroids that are more potent, at least one of which will be in e-bol. if you can find a source for turkesterone that is quality and isn't so expensive that you have to mortgage your house, then buy a bunch of it and growPrime Signature Real Estate for Rent
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06-13-2006, 12:35 PM #14
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06-13-2006, 12:37 PM #15
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06-13-2006, 12:39 PM #16
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06-13-2006, 12:43 PM #17Originally Posted by HalleluYAHPrime Signature Real Estate for Rent
Advertise Here!
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06-13-2006, 12:44 PM #18
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06-13-2006, 12:59 PM #19Originally Posted by 391rippy
"there are two main extracts of ecdysterone. 20-hydroxyecdysone from rhaponcticum carthamoides, which is what was used in russia and has numerous studies on it. there is also 20-hydroxyecdysterone extracted from cyanatis vega, which has little research on it and is the type that scivation will be using in their products. gram for gram, cyanatis vega is cheaper, however it requires a much higher dosage to get results, so in the end they come out costing about the same. there are a few bulk suppliers of ecdy from cyanatis vega, and if you want a bulk amount of ecdysten, PM me and i'll see what i can work out for you."Psalms 51:10-13
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06-13-2006, 01:15 PM #20
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06-13-2006, 01:23 PM #21
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06-13-2006, 01:25 PM #22
- Join Date: Jul 2004
- Location: Burlington, North Carolina, United States
- Posts: 26,552
- Rep Power: 23156
Originally Posted by HalleluYAH
This is ALL we want, whether it is from Suma, Rhaponticum or Cyanotis. People have different views on this obviously.www.scivation.com
Follow Us On
********: http://www.********.com/scivation
Instagram: http://instagram.com/scivation
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06-13-2006, 01:27 PM #23Originally Posted by Scivation
"The research indicated that the whole extract of Rhaponticum carthamoides containing mixture of levseins possess much superior physiological activity compared with the activity of purified individual constituents (Seifulla 1999)."Psalms 51:10-13
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06-13-2006, 01:31 PM #24
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06-13-2006, 01:33 PM #25
- Join Date: Jul 2004
- Location: Burlington, North Carolina, United States
- Posts: 26,552
- Rep Power: 23156
Originally Posted by HalleluYAH
We have seen great results with the extract and formula contained in Anagen.www.scivation.com
Follow Us On
********: http://www.********.com/scivation
Instagram: http://instagram.com/scivation
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06-13-2006, 01:33 PM #26Originally Posted by HalleluYAHPrime Signature Real Estate for Rent
Advertise Here!
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06-13-2006, 01:53 PM #27
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06-13-2006, 01:56 PM #28Originally Posted by Mr. Aries
it's supposed to be very anabolic, only problem is getting a quality source at a decent price. some other ecdysteroids may not be as potent mg per mg, but are more cost effective, which is more importantPrime Signature Real Estate for Rent
Advertise Here!
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06-13-2006, 02:02 PM #29
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06-13-2006, 02:04 PM #30
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