Interesting article but far from convincing. If you look at the original article I think you will appreciate that the website skews what the authors concluded as well. Myostatin levels dropped in strength training group compared to the no exercise group(duh); the strength training + creatinine group had a larger drop in myostatin than the strength training alone group (this would be expected with the larger increase in strength but could be a secondary effect). There was not a no exercise + creatinine group to see if creatinine alone decreased myostatin. The ergo folks put emphasis on GASP-1 levels increasing with resistance + creatinine which they did go up but not significantly more than resistance exercise alone . . . so this increase could be related to resistance training alone augmented by creatinine supplementation.
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Thread: Myostatin blockers
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01-19-2011, 04:02 AM #31
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- Location: Indianapolis, Indiana, United States
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Disclaimer: While I have an M.D. the views I express are not to be taken as medical advice under any circumstances. Please check with your own doctor if you want medical advice as he/she has access to your info and can provide the most accurate advice.
www.pubmed.gov . . . gotta love it
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01-29-2011, 04:05 PM #32
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01-29-2011, 09:39 PM #33
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08-14-2012, 02:11 AM #34
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07-23-2013, 11:29 AM #35
I would advise looking at some currently available anti cancer drugs for use as myostatin inhibitors. Myostatin is a small molecule that bonds to TGF-beta family receptors. There are several drugs on the market that inhibit the function of this receptor. I'm not sure how available these inhibitors are on the open market, but I Do know that certain drugs like novladex (used for breast cancer) can be easily obtained. It is therefore possible that the TGF-beta inhibitors can be obtained. Btw, novladex will not inhibit myostatin.
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07-29-2013, 06:38 PM #36
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08-20-2013, 11:35 AM #37
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