Overall Health-Oriented Supplements

[user27629377]

well i would be worried about the medical drugs it messes with, my family history isn't the best so I guess I was speaking for myself there

It's always a good idea to be safe, but I wouldn't completely count out a supplement based on a Wikipedia article. If there are certain medications that concern you, I would look into interactions between those specific medications and garlic.

[Heracles25]

I have a hard to reading and understanding these abstracts. Does this one below mean there is no muscle building or any type of positive benefits for enhancing performance?

Effect of glycine propionyl-L-carnitine on aerobic and anaerobic exercise performance.Smith WA, Fry AC, Tschume LC, Bloomer RJ.
Dept. of Health and Sport Sciences, University of Memphis, Memphis, TN 38152, USA.

The purpose of this study was to evaluate the effect of glycine propionyl-L-carnitine (GPLC) supplementation and endurance training for 8 wk on aerobic- and anaerobic-exercise performance in healthy men and women (age 18-44 yr). Participants were randomly assigned to 1 of 3 groups: placebo (n=9), 1 g/d GPLC (n=11), or 3 g/d GPLC (n=12), in a double-blind fashion. Muscle carnitine (vastus lateralis), VO(2peak), exercise time to fatigue, anaerobic threshold, anaerobic power, and total work were measured at baseline and after an 8-wk aerobic-training program. There were no statistical differences (p> .05) between or within the 3 groups for any performance-related variable or muscle carnitine concentrations after 8 wk of supplementation and training. These results suggest that up to 3 g/d GPLC for 8 wk in conjunction with aerobic-exercise training is ineffective for increasing muscle carnitine content and has no significant effects on aerobic- or anaerobic-exercise performance.

[kincaid82]

I have a hard to reading and understanding these abstracts. Does this one below mean there is no muscle building or any type of positive benefits for enhancing performance?

Effect of glycine propionyl-L-carnitine on aerobic and anaerobic exercise performance.Smith WA, Fry AC, Tschume LC, Bloomer RJ.
Dept. of Health and Sport Sciences, University of Memphis, Memphis, TN 38152, USA.

The purpose of this study was to evaluate the effect of glycine propionyl-L-carnitine (GPLC) supplementation and endurance training for 8 wk on aerobic- and anaerobic-exercise performance in healthy men and women (age 18-44 yr). Participants were randomly assigned to 1 of 3 groups: placebo (n=9), 1 g/d GPLC (n=11), or 3 g/d GPLC (n=12), in a double-blind fashion. Muscle carnitine (vastus lateralis), VO(2peak), exercise time to fatigue, anaerobic threshold, anaerobic power, and total work were measured at baseline and after an 8-wk aerobic-training program. There were no statistical differences (p> .05) between or within the 3 groups for any performance-related variable or muscle carnitine concentrations after 8 wk of supplementation and training. These results suggest that up to 3 g/d GPLC for 8 wk in conjunction with aerobic-exercise training is ineffective for increasing muscle carnitine content and has no significant effects on aerobic- or anaerobic-exercise performance.

I can assure you after reading this, i come to the absolute conclusion i am in the same boat as you.

Today?s order,

Scivation Whey 10 lbs
ON Casin
Omega- 3 mood
Ubiquinol
Astaxanthin
SAMe
Garlic-Still trying to decide on which one.

[johnsonb90436]

These results suggest that up to 3 g/d GPLC for 8 wk in conjunction with aerobic-exercise training is ineffective for increasing muscle carnitine content and has no significant effects on aerobic- or anaerobic-exercise performance.

glycine propionyl-L-carnitine = GPLC

"Carnitine is a quaternary ammonium compound biosynthesized from the amino acids lysine and methionine.[1] In living cells, it is required for the transport of fatty acids from the cytosol into the mitochondria during the breakdown of lipids (or fats) for the generation of metabolic energy."

So as i read this i believe that they where trying to increase work out performance, (and it says it in the quote) L-carnitine didn't help the subjects work out any harder thus aiding in muscle growth or fat loss...

[johnsonb90436]

exercise time to fatigue, anaerobic threshold, anaerobic power, and total work were measured at baseline and after an 8-wk aerobic-training program

also this is what they based the subjects gains on

[johnsonb90436]

i dont mean to flood the this thread. But i wonder the diet of the subjects, we all know that the diet plays a big role in strenth gains. If the subjects weren't eating enough lean meats, carbs and fats then i believe they wouldn't see gains from the glycine propionyl-L-carnitine anyways.

[kincaid82]

i dont mean to flood the this thread. But i wonder the diet of the subjects, we all know that the diet plays a big role in strenth gains. If the subjects weren't eating enough lean meats, carbs and fats then i believe they wouldn't see gains from the glycine propionyl-L-carnitine anyways.

very good point, just seems so many things, may and may not help, it's hard to put together a core group. Right now for me it's

MVP-365
AN's Bio-Mend
Now Foods SAMe
Ubiquinol
Astaxanthin

[user27629377]

very good point, just seems so many things, may and may not help, it's hard to put together a core group. Right now for me it's

MVP-365
AN's Bio-Mend
Now Foods SAMe
Ubiquinol
Astaxanthin

You have to be careful about buying SAMe that does not come in individual foil packs, SAMe is an extremely unstable compound.

[kincaid82]

You have to be careful about buying SAMe that does not come in individual foil packs, SAMe is an extremely unstable compound.

i saw that once before, might have been you that put it up, may switch that up and try one the is foil packed. the now Foods is coated it that helps at all, and i store it in the fridge.

[user27629377]

i saw that once before, might have been you that put it up, may switch that up and try one the is foil packed. the now Foods is coated it that helps at all, and i store it in the fridge.

SAMe is also not supposed to be refrigerated

It is important to purchase enteric-coated tablets packaged in foil or foil blister packs. SAMe should be stored in a cool, dry place, but not refrigerated. Tablets should be kept in the blister pack until the time of ingestion.

I find it weird that NOW markets their SAMe the way they do, when almost everywhere else that I read, besides the NOW bottle, recommends individual foil packaging and no refrigeration.

[factotum]

I have a hard to reading and understanding these abstracts. Does this one below mean there is no muscle building or any type of positive benefits for enhancing performance?

Effect of glycine propionyl-L-carnitine on aerobic and anaerobic exercise performance.Smith WA, Fry AC, Tschume LC, Bloomer RJ.
Dept. of Health and Sport Sciences, University of Memphis, Memphis, TN 38152, USA.

The purpose of this study was to evaluate the effect of glycine propionyl-L-carnitine (GPLC) supplementation and endurance training for 8 wk on aerobic- and anaerobic-exercise performance in healthy men and women (age 18-44 yr). Participants were randomly assigned to 1 of 3 groups: placebo (n=9), 1 g/d GPLC (n=11), or 3 g/d GPLC (n=12), in a double-blind fashion. Muscle carnitine (vastus lateralis), VO(2peak), exercise time to fatigue, anaerobic threshold, anaerobic power, and total work were measured at baseline and after an 8-wk aerobic-training program. There were no statistical differences (p> .05) between or within the 3 groups for any performance-related variable or muscle carnitine concentrations after 8 wk of supplementation and training. These results suggest that up to 3 g/d GPLC for 8 wk in conjunction with aerobic-exercise training is ineffective for increasing muscle carnitine content and has no significant effects on aerobic- or anaerobic-exercise performance.

The study results would indicate that GPLC has little effect on aerobic exercise and they could not find an increase in intramuscular stores of carnitine which I guess they would expect with GPLC usage. I can see a few flaws but without the entire study I can only guess at the protocols employed. But it appears that the subjects only conducted aerobic training and after 8 weeks had no increase over placebo and also no effect on anaerobic training. But if you run on a treadmill for 8 weeks I doubt you'd see much of an increase in your bench press. Of course, without the specifics, we don't know how they measured anaerobic performance.

[kincaid82]

SAMe is also not supposed to be refrigerated



I find it weird that NOW markets their SAMe the way they do, when almost everywhere else that I read, besides the NOW bottle, recommends individual foil packaging and no refrigeration.

well interesting, well looks like i am switching, what was the SAMe that everyone here seemed to recomend.

[user27629377]

well interesting, well looks like i am switching, what was the SAMe that everyone here seemed to recomend.

I would go with Jarrow or AOR

[Heracles25]

Thanks for the reply and help Jonhson and Wanderlei!

[johnsonb90436]

Thanks for the reply and help Jonhson and Wanderlei!

Glad to help

[Doughboy]

Anyone here using Toco 8 or have an opinion on it?

[wrstdude]

Also, for those taking Trans-Resveratrol, what brand/brands are you using? Anything 98%/99% pure?

Anyone got any info they'd like to share? I'm having a hard time finding a good Trans-Resveratrol product.

[drxmn]

I bought 2 glyc-n-go from w2b yesterday, great deal. I might go pick up some ubiquinol from VS tomorrow.

[niktak11]

Anyone got any info they'd like to share? I'm having a hard time finding a good Trans-Resveratrol product.

Check out AOR's and Bioforte's resveratrol. I'm not currently taking resveratrol but it seems like the majority of people I see taking it have recommended these 2.

[kincaid82]

what is everyone opinon on the Doctor's best line, they have SAMe coated and foil packed for about 10 bucks less than Jarrow?

[user27629377]

what is everyone opinon on the Doctor's best line, they have SAMe coated and foil packed for about 10 bucks less than Jarrow?

wow, that would be the cheapest SAMe available i would imagine. I will look in to it.

[Doughboy]

wow, that would be the cheapest SAMe available i would imagine. I will look in to it.

I am pretty sure they are not cGMP.

[kincaid82]

I am pretty sure they are not cGMP.

looked back and you are the one who told me about Doctor's best, below is what you stated

"I got 30 tabs blister packed for $17 - 400mg"

[user27629377]

I am pretty sure they are not cGMP.

You are correct, just checked their website.

[kincaid82]

You are correct, just checked their website.

i just e-mail them and they said they were, is there a certification i can ask for.

[user27629377]

i just e-mail them and they said they were, is there a certification i can ask for.

What did you ask them? If you ask them if they are cGMP compliant, they can say "yes" even if they aren't certified. To be cGMP compliant all you have to do is follow the rules of the statute, certification is another thing.

On their website it says they basically rely on HPLC and COA from their supplier, I didn't see any mention of cGMP.

[kincaid82]

What did you ask them? If you ask them if they are cGMP compliant, they can say "yes" even if they aren't certified. To be cGMP compliant all you have to do is follow the rules of the statute, certification is another thing.

On their website it says they basically rely on HPLC and COA from their supplier, I didn't see any mention of cGMP.

ok thanks, for clearing that up, learn something new every day on here.

[user27629377]

This website is messed up right now, I can't quote anyone and I can't scroll down in this thread past where wanderlei was discussing GPLC, but kincaid, since they have replied to you, write back and ask them if they are independently cGMP certified please, I would be interested to know.

[Doughboy]

looked back and you are the one who told me about Doctor's best, below is what you stated

"I got 30 tabs blister packed for $17 - 400mg"

Yes I did.

I was telling SCD that they were not cGMP because i know he does not buy from companies who are not.

[kincaid82]

This website is messed up right now, I can't quote anyone and I can't scroll down in this thread past where wanderlei was discussing GPLC, but kincaid, since they have replied to you, write back and ask them if they are independently cGMP certified please, I would be interested to know.

i have asked that exact quesiton. we will see