New muscletech product tomorow?

[KillerB84]

My other guess is HMB free acid. This actually lines up with the 16lbs in 12 weeks.



Dr. Jacob Wilson, PhD, CSCS – Effects of HMB Free Acid and Oral ATP on Human Performance

ISSN Position Statement – HMB: The details, background and in-depth discussion on HMB's mechanism of action, the different forms (HMB-FA vs. HMB-Ca), etc, is beyond the scope of this article, I refer you to the ISSN's HMB Position Statement for a more in-depth discussion on these areas.

Dr. Jacob Wilson presented twice at the ISSN conference. His first presentation focused on HMB-FA, Oral ATP & combinations of ATP + HMB. Unfortunately I was unable to attend this specific presentation due to a timing conflict with one of the other presentations I wanted to see. However, some of my friends attended it and shared with me the "high points" of the discussion. Additionally, I was able to catch some of the details from the poster session.

As late as a few years ago, it appeared that HMB was a supplement "dead in the water" with respect to research supporting its use in trained individuals. However, Dr. Wilson questioned if maybe the lack of results seen in these earlier studies were related to the training protocols which lacked the degree of intensity and novel training stimulus required to truly take advantage of HMB's ergogenic benefits (see sidebox). In yet to be published research, his team had 20 resistance trained males complete a 12 week training program that utilized undulating periodization (Monday – Hypertrophy emphasis w/ volume load of ~40,000 lbs, Wednesday – Power, Friday –Heavy). For reference, his "trained" participants had > 3 years of experience; their 1RM's for squat were ~ 1.7x bodyweight and for deadlift ~1.8x bodyweight. These men were randomized into one of two groups which consumed either HMB-FA (3g/d) or a placebo. All individuals were instructed on a diet that consisted of 25% protein, 50% carbs & 25% fat. At the end of the study, both groups had significant gains in overall body strength; however, despite having similar initial strength levels, those in the HMB group had significantly greater gains at the study's end. Positive benefits were also observed in muscle hypertrophy and fat loss in the HMB group as shown in Table 1. These gains occurred despite results indicating that both groups had similar kcal and macronutrient intake during the study.

Table 1. Changes in Strength & % Body Fat when combining HMB-FA supplementation with a 12 week undulating resistance training program. Baseline strength assessed via combined totals of squat, deadlift & bench press testing. Please note, the changes in body fat 's are not 100 accurate as they were based off my "eye-balling" the graph presented by Wilson JM13. Also "*" represents statistically significant vs. baseline; "#" represents statistically significant vs. placebo. Table created by Sean Casey. Data adapted from Dunmore et al12 and Wilson13

Group Baseline Strength Final Strength Initial % Body Fat Final % Body Fat Initial Quadriceps Thickness Final Quadriceps Thickness
HMB-FA (3g/d) 430.4 kg 507.5kg (+18.3%)*# ~21% ~14%*# 50.7 cm 57.8 cm (+14.5%)*#
Placebo 422.2kg 447.5kg (+6.6%)* ~21% ~19.5% 49.6 cm 52.0 cm (+4.6%)*

Switching gears here, Dr. Wilson's lab has also been examining the potential ergogenic effects of oral ATP supplementation. Their early research seems to indicate that oral ATP supplementation may increase muscle blood flow during exercise.1 This was shown in a pilot study where 12 resistance trained males took 400 mg ATP daily for 12 weeks. Additionally at weeks 1, 4, 8, and 12, individuals consumed 400 mg prior to completing an acute bicep curl training session (60 reps). Results indicated that at week 1, 8, 12, significant differences in blood flow were observed 0 and 3 minutes post exercise relative to baseline values. (Have we finally found the "holy grail" of muscle pump supplements?!)

What I'm not sure of is the exact mechanism leading to the increased blood flow observed in this pilot study presented at the conference. It was suggested, that supplemental ATP was carried on red blood cells (RBC) and released into the blood during muscular exertion. Although research has shown that intravenous ATP administration increases muscle blood flow, I have not seen anything to indicate that oral ATP or its metabolites (except uric acid) reach systemic circulation post ingestion. Doing a little digging post conference, I came across a 2012 study indicating that 5000 mg of oral ATP failed to increase circulating levels of ATP or its metabolites (uric acid being an exception) in human blood post ingestion.2 A similar lack of effects on circulating ATP and its metabolites were observed in a four week study using 250, 1250 or 5000 mg ATP per day.3 Now, these latter research studies assessed whole blood which would have included the RBC fraction. Thus, I'm left scratching my head on this one … So stay tuned!
- See more at: http://www.caseperformance.com/197/2....BqSQIObR.dpuf

[Mr.Cooper69]

I think you're 100% right, good looks

[chicago1963]

this is just more BS from MT just like allot of there claims, anyone who thinks they are going to gain 16lbs of muscle in 12 weeks is stupid! sorry but this is just silly.

[KillerB84]

this is just more BS from MT just like allot of there claims, anyone who thinks they are going to gain 16lbs of muscle in 12 weeks is stupid! sorry but this is just silly.

Actually, if it is indeed HMB Free Acid, there is a well done study using real training protocols on experienced lifters that back up the claim.

[KillerB84]

The only thing is hopefully it is dosed properly. The study used 3g per day, so let's hope you don't need to buy 3 bottles per month to get this dose.

[Mr.Cooper69]

The only thing is hopefully it is dosed properly. The study used 3g per day, so let's hope you don't need to buy 3 bottles per month to get this dose.

To make label claims you need to use the exact dose

[BogusForLife]

The only thing is hopefully it is dosed properly. The study used 3g per day, so let's hope you don't need to buy 3 bottles per month to get this dose.

90 1000mg caps for a month supply perhaps?

[KillerB84]

To make label claims you need to use the exact dose

Awesome!

[KillerB84]

90 1000mg caps for a month supply perhaps?

That sounds about right.

[KillerB84]

Here is the published study:

http://www.jissn.com/content/9/S1/P5

It says it was a gel, so that would explain the clear gel caps.

[Dewey99]

[Marshall28]

In!

[cbs]

Okay, I'll bite...we're waiting....

[BlueRev]

It's not ArA or a protein. I'm going to do everything in my power to get you all the details on the study etc asap.

[KillerB84]

It's not ArA or a protein. I'm going to do everything in my power to get you all the details on the study etc asap.

Right here, Broski: http://www.jissn.com/content/9/S1/P5

[reverse79]

University of tampa is 15 mins from me

Might have to meet this wilson character

I know layne does a lot of reasearch projects there too

[KrackinWise]

The only thing is hopefully it is dosed properly. The study used 3g per day, so let's hope you don't need to buy 3 bottles per month to get this dose.

most likely be 30 caps 1 cap per seving. recommend taking 2-3 servings a day.... were have we seen this before?

[Tito203]

16lbs of muscle in 12 weeks i gotta see that

[VaughnTrue]

most likely be 30 caps 1 cap per seving. recommend taking 2-3 servings a day.... were have we seen this before?

MT has stepped up their game as of late...I'd assume they have 84 gel-caps, for a 28 day supply. If they only have 30 pills/bottle, they wouldn't be able to make these claims as Cooper pointed out.

[Sephra]

University of tampa is 15 mins from me

Might have to meet this wilson character

I know layne does a lot of reasearch projects there too

he's really nice and I've met and worked with him (go to USF). Pretty crazy to think how UT is doing all of this. Jacob is an honest and good person.

[llahhsoj]

I am looking forward to this product. I know as much as you all about the profile at this point.

[johanlohman]

Following with interest...

[chicago1963]

Well 16lbs in 12 weeks would certainly be ground breaking now wouldn't it? I find this really hard to believe and honestly don't, but if I'm wrong we should all look like Arnold by the end of the year and can you imagine what all the professionals bodybuilders will look like once there get there hands on these magic pills, lol MT you have out done yourself

[Valhallabound86]

16 lbs of muscle and I could still drink alcohol while on it? I'm skeptical, but will reserve judgements.

[Nyrin]

I'm guessing we're talking 16 pounds lean mass here, which would include glycogen and bound water for new muscle. Not that it isn't still a pretty incredulous claim (unless it's caveated with untrained or detrained participants in the study, and so on), but I'm still in on this for the popcorn!

[bmilligan15]

Following with interest...

same here

[Madevilz]

16 lbs of muscle and I could still drink alcohol while on it? I'm skeptical, but will reserve judgements.

even with steroids you dont gain 16 lbs of pure muscle in 12 weeks.

[VaughnTrue]

even with steroids you dont gain 16 lbs of pure muscle in 12 weeks.

they're quoting "lean mass", correct? or do the adds say "pure muscle"? these two are very different.

[KillerB84]

they're quoting "lean mass", correct? or do the adds say "pure muscle"? these two are very different.

It says "Lean Muscle", but this is misleading since the study states "Lean Mass"

[BogusForLife]

they're quoting "lean mass", correct? or do the adds say "pure muscle"? these two are very different.

I gain a fourth of that in less than a week if I've not eaten enough fiber and drank enough water.

It says "Lean Muscle", but this is misleading since the study states "Lean Mass"

Combine with Cell-Tech for nearly exponential gains!

"SUBJECTS GAINED 3.4 LBS. OF
MUSCLE IN 7 DAYS!1

Subjects who consumed the amount of creatine and carbohydrates supplied during the CELL-TECH loading stage (see directions) gained, on average, 3.4 pounds of muscle in 7 days. Subjects taking creatine with juice gained only 0.8 pounds.1"