Ginger and dem DOMS (study)

[WillBrink]

More ginger on my sushi

Ginger appears effective for reducing DOMS:

The Effects of Pre-Exercise Ginger Supplementation on Muscle Damage and Delayed Onset Muscle Soreness

Ginger possesses analgesic and pharmacological properties mimicking non-steroidal antiinflammatory drugs. We aimed to determine if ginger supplementation is efficacious for attenuating muscle damage and delayed onset muscle soreness (DOMS) following high-intensity resistance exercise.

Following a 5-day supplementation period of placebo or 4 g ginger (randomized groups), 20 non-weight trained participants performed a high-intensity elbow flexor eccentric exercise protocol to induce muscle damage. Markers associated with muscle damage and DOMS were repeatedly measured before supplementation and for 4 days following the exercise protocol. Repeated measures analysis of variance revealed one repetition maximum lift decreased significantly 24 h post-exercise in both groups (p < 0.005), improved 48 h post-exercise only in the ginger group (p = 0.002), and improved at 72 (p = 0.021) and 96 h (p = 0.044) only in the placebo group.

Blood creatine kinase significantly increased for both groups (p = 0.015) but continued to increase only in the ginger group 72 (p = 0.006) and 96 h (p = 0.027) post-exercise. Visual analog scale of pain was significantly elevated following eccentric exercise (p < 0.001) and was not influenced by ginger.

In conclusion, 4 g of ginger supplementation may be used to accelerate recovery of muscle strength following intense exercise but does not influence indicators of muscle damage or DOMS.

http://onlinelibrary.wiley.com/doi/1....5328/abstract

[AMeyer9]

Why do they gotta do all of these studies on "non-weight trained participants"

[WillBrink]

Why do they gotta do all of these studies on "non-weight trained participants"

Not all of them are done on un trained people, but for sure, using un trained people can skew the results depending on what you're attempting to examine

[mtpaquette]

Not all of them are done on un trained people, but for sure, using un trained people can skew the results depending on what you're attempting to examine

Especially when it comes to DOMS.

[Bigdumogre]

Came in hoping to see sexy red headed women
Left confused

[BULLED]

In for hot redheads eating ginger!

[AMeyer9]

In for hot redheads eating ginger!

[DasBiceps]

In for hot redheads eating ginger!

[neuron]

Serum CK "continued to rise" in the ginger group? Whats the mechanism there, especially with apparent ability to decrease DOMS?

[neuron]

Serum CK "continued to rise" in the ginger group? Whats the mechanism there, especially with apparent ability to decrease DOMS?

Anybody?

[eatyourspinach]

Anybody?

It isn't specific to the OP but in "Phase II Study of the Effects of Ginger Root Extract on Eicosanoids in Colon Mucosa in People at Normal Risk for Colorectal Cancer" it was implied that ginger might inhibit COX-1 so maybe it's relevant to the OP? (pdf in case you haven't read it http://cancerpreventionresearch.aacr.../1929.full.pdf)

[chemo29]

Why do they gotta do all of these studies on "non-weight trained participants"

at least they're humans...



yes I'm thinking about you guys transposing your dolphin studies to humans

Increased Dietary Intake of Saturated Fatty Acid Heptadecanoic Acid (C17:0) Associated with Decreasing Ferritin and Alleviated Metabolic Syndrome in Dolphins
http://journals.plos.org/plosone/art...l.pone.0132117

[AMeyer9]

at least they're humans...



yes I'm thinking about you guys transposing your dolphin studies to humans

How exactly does one measure DOMS in an animal anyways

[Mr.Cooper69]

It isn't specific to the OP but in "Phase II Study of the Effects of Ginger Root Extract on Eicosanoids in Colon Mucosa in People at Normal Risk for Colorectal Cancer" it was implied that ginger might inhibit COX-1 so maybe it's relevant to the OP? (pdf in case you haven't read it http://cancerpreventionresearch.aacr.../1929.full.pdf)

COX-1 is more specific to platelets and the gi mucosa, and it is constitutively expressed, so the relevance here is nil.

[Mr.Cooper69]

Am I missing something or is the conclusion misleading? Ginger improves muscular function acutely but worsens it at days 3 and 4 relative to taking nothing. This certainly isn't very promising for ginger supplementation. This just seems like one of a host of antioxidants that are cytoprotective initially, then increase ROS and accelerate muscle damage/worsen recovery further on.

[MuscleUpCrohns]

Am I missing something or is the conclusion misleading? Ginger improves muscular function acutely but worsens it at days 3 and 4 relative to taking nothing. This certainly isn't very promising for ginger supplementation. This just seems like one of a host of antioxidants that are cytoprotective initially, then increase ROS and accelerate muscle damage/worsen recovery further on.

From the full text of the study, the discussion said the following:

The mechanism behind this accelerated recovery may be related to ginger delaying actual muscle damage itself, as evidenced by a more gradual increase in CK compared with placebo...

It appears that this ginger supplementation protocol delayed muscle damage but did not prevent it.

Recently, I've also been doing some research regarding supplements for horses, and came across a study on ginger that said the following (I know, it's not a study in humans, but I found it interesting):

A major finding of this study was that ginger extract reduced recovery (defined as the time for VO2 to recover from the peak observed at fatigue to a post-exercise plateau)...

Unfortunately, the above positive benefit was outweighed by ginger's effect on markers of muscle membrane damage and inflammatory cytokines, with a strong increase in the upregulation and expression of mRNA for the pro-inflammatory cytokine TNF-α...

[Gwyndane]

food sleep and increased frequency decreases doms will

[Mr.Cooper69]

From the full text of the study, the discussion said the following:


Recently, I've also been doing some research regarding supplements for horses, and came across a study on ginger that said the following (I know, it's not a study in humans, but I found it interesting):

Indeed, this is similar to what I was saying. It looks like it draws out muscle cell membrane damage, allowing continued leakage of CK and extended damage. Good find

[MuscleUpCrohns]

Indeed, this is similar to what I was saying. It looks like it draws out muscle cell membrane damage, allowing continued leakage of CK and extended damage. Good find

Thanks. Perhaps a bit off topic, but what do you think of blueberries and this study:
"Effect of New Zealand blueberry consumption on recovery from eccentric exercise-induced muscle damage"

In a randomized cross-over design, 10 females consumed a blueberry smoothie or placebo of a similar antioxidant capacity 5 and 10 hours prior to and then immediately, 12 and 36 hours after EIMD induced by 300 strenuous eccentric contractions of the quadriceps. Absolute peak and average peak torque across the knee, during concentric, isometric, and eccentric actions were measured. Blood biomarkers of oxidative stress, antioxidant capacity, and inflammation were assessed at 12, 36 and 60 hours post exercise. Data were analyzed using a two-way ANOVA.

In conclusion, our study provides evidence that ingestion of a New Zealand blueberry beverage prior to and after eccentric muscle damage accelerates recovery of muscle peak isometric strength, independent of the beverages inherent antioxidant properties...

This study has practical implications for all who turn to exercise and dietary antioxidant-rich supplements to maintain their health and performance. It is especially of potential relevance to all athletes who compete over successive days as well as to the general sporting community. Although the literature is divided as to the benefits of antioxidant supplements in affecting the initial muscle damage/inflammation and subsequent recovery of muscle function, this study supports the idea that blueberry consumption induces cellular adaptive events that serve to accelerate muscle repair and recovery of muscle isometric strength. Identifying specific dietary interventions that complement exercise-induced short-term as well as adaptive responses following various exercise strategies (i.e. aerobic exercise-induced oxidative stress or EIMD) may be of greater importance in maintaining health and athletic performance than the consumption of generic dietary supplements based upon their apparent high antioxidant capacity...

Conclusion:
This study demonstrates that the ingestion of a blueberry smoothie prior to and after EIMD accelerates recovery of muscle peak isometric strength. This effect, although independent of the beverage’s inherent antioxidant capacity, appears to involve an up-regulation of adaptive processes, i.e. endogenous antioxidant processes, activated by the combined actions of the eccentric exercise and blueberry consumption. These findings may benefit the sporting community who should consider dietary interventions that specifically target health and performance adaptation.

http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3583121/

[neuron]

Indeed, this is similar to what I was saying. It looks like it draws out muscle cell membrane damage, allowing continued leakage of CK and extended damage. Good find

What does "draw out muscle cell membrane damage" mean? Increased serum CK is generally thought of as loss of membrane integrity, which is a bad thing. Maybe I misunderstood what you said...

[neuron]

It isn't specific to the OP but in "Phase II Study of the Effects of Ginger Root Extract on Eicosanoids in Colon Mucosa in People at Normal Risk for Colorectal Cancer" it was implied that ginger might inhibit COX-1 so maybe it's relevant to the OP? (pdf in case you haven't read it http://cancerpreventionresearch.aacr.../1929.full.pdf)

My question is only in reference to the apparent ginger pardox: decreased DOMs and increased signs of systemic muscle damage.

[neuron]

Nevermind, muscleup quotes the fulltext in post #16.