Neogenix Supremacy goes "au naturale" --- Formula Updated!

[user98511001541]

Neogenix Supremacy

After careful consideration of the formula, Supremacy has been revamped! We have taken out the 6-bromo and instead added Indole-3-carbinol (I3C), this allows our product to still offer the same amazing body recomp effects but now we are using all natural ingredients! If anyone was considering using Supremacy, but was worried about trying out an aromatose inhibitor, now is your chance! I3C will help control estrogen the same as 6-bromo, so the effects are still there! Bodybuilding.com has the new formula but has not updated their website, so rest assured it is there and in stock!

We are excited to be able to offer this new formula to the Bodybuilding.com members, we are always looking to impress our valued customers! Thank you everyone for your continued support and look for big things to come in the future from Neogenix!




Supremacy? is a synergistic matrix of specialized herbal extracts designed to optimize endogenous hormone levels for enhancing muscle growth while accelerating fat loss. This is systematically done by modulating estrogen levels, indirectly increasing testosterone production, freeing bound inactive testosterone, and reducing cortisol and prolactin levels while improving nutrient utilization.

By optimizing hormone levels this way, we are able to positively influence the anabolic/catabolic ratios within your body. With this positive balance comes an environment where muscle builds faster and fat burns more efficiently. This allows Supremacy? to favorably augment body composition in the safest, most efficient way possible - naturally.

Users of Supremacy? are reporting average muscle gains in excess of one pound of lean muscle mass per week with a noticeable loss of bodyfat occurring simultaneously. Best of all, this is accomplished without any negative impact on natural hormone production.

For maximum results, a dosing protocol of up the 8-weeks may be utilized by athletes wanting to experience the full muscle building/hormone optimizing potential only Supremacy? can provide!



Supremacy? features a Pro-Anabolic blend of:

∙ Cissus Quadrangularis Ketosterone Extract contains a unique blend of vitamins and minerals with a standardized amount of plant sterol compounds that has been shown to strengthen the tissues of the body. By using this high potency extract we can deliver the proper ratios of this active compound to the target sites with precision. This unique extract has been shown to effectively reduce catabolic hormones thus enhancing the recovery of muscles, tendons, ligaments and even bone.

∙ Urtica Dioica Lignan Complex contains an excellent testosterone optimizing compound called Conjugated (-)3,4-divanillyl-tetrahydrofuran. This produces a positive effect upon free/active circulating testosterone levels by unbinding bound inactive testosterone back it into circulation for use in the body while reducing BPH which can arise from DHT conversion, a natural reaction caused by any increase in testosterone levels. The result is more testosterone to bind to androgen receptors and produce a favorable response - muscle growth!

∙ Mormordica Chirantia Extract contains compounds that can be derived only thorough specialized extraction processes that possesses super potent hypoglycemic properties. These extracts have been shown to effectively modulate blood-sugar levels by increasing glucose utilization for accelerated intracellular nutrient transport and delivery.

∙ Vitex Agnus Monoterpene Complex contains several different constituents, including flavonoids, iridoid glycosides, and terpenoids which possess prolactin-suppressive properties. The benefits of Vitex stem from its actions upon the pituitary gland, specifically on the production of a hormone called luteinizing hormone (LH). This indirectly increases testosterone production while also helping keep prolactin secretions in check.

∙ Indole-3-carbinol (I3C) is a naturally occurring photochemical which provides primarily antioxidant protection, but also modulates estrogen metabolism within the body. It does this by decreasing the production of the 16-hydroxy metabolites; ?bad? estrogens, in favor of the 2-hydroxy metabolites; ?good? estrogens. This optimizes the ratio of testosterone to estrogen; leading to a hormonal balance which is more ideal for muscular growth.

∙ Forskohlii Diterpine Complex directly stimulates the enzyme adenylate cyclase, and subsequently the cell-regulating substance called cyclic adenosine monophosphate (cAMP). By stimulating cAMP, circulating hormones are optimized for enhanced utilization for extended periods of time, overcoming any receptor site down-regulation that may occur with an extended dosing protocol.

∙ Piper Nigrum Extract has been shown to enhance the absorption of nutrients and increases the percentage of active ingredients that reach the target cells. This means better absorption while also extending the active half-life of several muscle building ingredients found only in Supremacy?.

http://www.bodybuilding.com/store/neo/sup.html

Here are some supremacy reviews:

http://forum.bodybuilding.com/showth...premacy+review

http://forum.bodybuilding.com/showth...premacy+review

http://forum.bodybuilding.com/showth...premacy+review

http://forum.bodybuilding.com/showth...premacy+review

[theone787]

so what exactly makes i3c natural and 6bromo not? I was always wary of ai's but now i'm actually interested in this stuff.

[Push Press Potts]

so what exactly makes i3c natural and 6bromo not? I was always wary of ai's but now i'm actually interested in this stuff.

Indole-3-Carbinol (I3C) is a naturally occurring phytochemical found in cruciferous vegetables such as cabbage, broccoli, and kale.

[theone787]

Indole-3-Carbinol (I3C) is a naturally occurring phytochemical found in cruciferous vegetables such as cabbage, broccoli, and kale.

so would it be less effective than 6bromo? from what i gather, it's a milder substance

[Push Press Potts]

so would it be less effective than 6bromo? from what i gather, it's a milder substance

i dont possess the knowledge to answer that

[theone787]

i dont possess the knowledge to answer that

haha it's all good. thanks man

[Stonecoldtruth]

Indole-3-Carbinol (I3C) is a naturally occurring phytochemical found in cruciferous vegetables such as cabbage, broccoli, and kale.

And for those who like studies.. I dug up a few.. Read the fulls to see the coorelation to estrogen.

Michenovicz JJ, et al. Changes in estrogen metabolites after oral indole-3-carbinol treatment in humans. J. Natl Cancer Inst 1997;89(10):718-23.

Michenovicz JJ, et al. Dietary and pharmacological control of estradiol metabolism in humans. ANN NY Acad Sci 1991;595:291-9

Yuan F, Chen DZ, Liu K, et al. Anti-estrogenic activities of indole-3-carbinol in cervical cells: implication for prevention of cervical cancer. Anticancer Res. 1999;19:1673-1680.

Bradlow HL, Sepkovic DW, Telang NT, et al. Multifunctional aspects of the action of indole-3-carbinol as an antitumor agent. Ann N Y Acad Sci. 1999;889:204-213.

Meng Q, Yuan F, Goldberg ID, et al. Indole-3-carbinol is a negative regulator of estrogen receptor-alpha signaling in human tumor cells. J Nutr. 2000;130:2927-293l .

[user98511001541]

so what exactly makes i3c natural and 6bromo not? I was always wary of ai's but now i'm actually interested in this stuff.

PPP was right on track

Indole-3-Carbinol (I3C) is a naturally occurring phytochemical found in cruciferous vegetables such as cabbage, broccoli, and kale.

BINGO!

so would it be less effective than 6bromo? from what i gather, it's a milder substance

it is completely different in that i3C is not an aromatose inhibitor, but rather a phytochemical that has an ability to alter estrogen metabolism. What's also pretty interesting is that there current and ongoing research supporting I3C's ability to decrease tumor size and, hopefully, combat cancer cells. I3C is composed of many metabolites and it seems that many different metabolites provide anti-estrogen functions, so perhaps this may be even more effective than 6-bromo at estrogen control. This quote shows the different metabolites and how they effect estrogen:

"Both I3C5 and ICZ6 compete with estrogen for binding
sites. DIM has been shown to selectively bind to estrogen receptors, and may act as an estrogen antagonist at
physiological concentrations.7 Other research has focused on the ability of
I3C metabolites, specifically DIM and ICZ, to induce
the cytochrome p450 isoenzymes CYP1A1 and
CYP1A2.3,8 Through its action on these enzymes, I3C
alters the pathway of estrogen metabolism in human
males and females in a manner that decreases the risk
of certain tumors.9-11"

http://www.thorne.com/media/Indole_mono10-4.pdf


I am by no means a scientist or anything, but hope this helps! Any other questions i'll try my best to answer, and should I not know the answer, I'll get the owner/lead designer Shaun (sdr@neogenix) to stop by and share some knowledge.

[theone787]

PPP was right on track



BINGO!



it is completely different in that i3C is not an aromatose inhibitor, but rather a phytochemical that has an ability to alter estrogen metabolism. What's also pretty interesting is that there current and ongoing research supporting I3C's ability to decrease tumor size and, hopefully, combat cancer cells. I3C is composed of many metabolites and it seems that many different metabolites provide anti-estrogen functions, so perhaps this may be even more effective than 6-bromo at estrogen control. This quote shows the different metabolites and how they effect estrogen:

"Both I3C5 and ICZ6 compete with estrogen for binding
sites. DIM has been shown to selectively bind to estrogen receptors, and may act as an estrogen antagonist at
physiological concentrations.7 Other research has focused on the ability of
I3C metabolites, specifically DIM and ICZ, to induce
the cytochrome p450 isoenzymes CYP1A1 and
CYP1A2.3,8 Through its action on these enzymes, I3C
alters the pathway of estrogen metabolism in human
males and females in a manner that decreases the risk
of certain tumors.9-11"

http://www.thorne.com/media/Indole_mono10-4.pdf


I am by no means a scientist or anything, but hope this helps! Any other questions i'll try my best to answer, and should I not know the answer, I'll get the owner/lead designer Shaun (sdr@neogenix) to stop by and share some knowledge.

wow thanks for all the info...so from what i gather, it's like an ai but without the usual sides associated with ai's? is this sort of correct?

[ponshoe]

yay no more broccoli !

Great man, supremacy rocks!

[user98511001541]

wow thanks for all the info...so from what i gather, it's like an ai but without the usual sides associated with ai's? is this sort of correct?

Pretty much It is more costly to use but it better serves our target market (natural athletes) and offers the same great benefits!

yay no more broccoli !

Great man, supremacy rocks!

brocolli is soooo amazing for you you better still eat it!

but i agree, supremacy is the ****

[liftjunkie06]

Looks good. I personally avoid artificial stuff so kudos on that!

[user98511001541]

Looks good. I personally avoid artificial stuff so kudos on that!

yep a lot of people feel the same way! we still have the 6-bromo in regenesen, but supremacy is for our all natural athletes!

[SMac2347]

Nice change. I would not have tried Supremacy before, but with the formula alteration I may have to give it a go sometime in the future.

[NeoRudyx]

I like!!

[user98511001541]

Nice change. I would not have tried Supremacy before, but with the formula alteration I may have to give it a go sometime in the future.

yeah seems like a lot of people were turned off, so we listened! If you want something a little more kick in the pants, we still have full dosed regenesen for ya!

I like!!

i like you!


(no homo)

[ksujosh6]

did you ask your bosses if the reason for the change is what i talked about in the gym?

[user98511001541]

did you ask your bosses if the reason for the change is what i talked about in the gym?

yep

yoda voice: "so smart, young joshua is"

[ksujosh6]

yep

yoda voice: "so smart, young joshua is"

and you thought I was just a no nothing board rep

[NeoRudyx]

and you thought I was just a no nothing board rep

oh well...

[MBSowards]

I I3C what you guys did there.

^^Did you see what I did there?

Good looking update. I know there was at least one guy I talked to a while back that would be more likely to use the product now.

[NeoRudyx]

I I3C what you guys did there.

^^Did you see what I did there?

Good looking update. I know there was at least one guy I talked to a while back that would be more likely to use the product now.

I3C, I3C....

[-SDR-]

This new formula really does rock! Ive been taking it standalone for the past 5 weeks and the muscle gains and fat loss are definitely an improvement over the old formula. I think anyone who has tried Supremacy in the past, who then tries this; will be pleasantly surprised as well.

[pa mma]

This new formula really does rock! Ive been taking it standalone for the past 5 weeks and the muscle gains and fat loss are definitely an improvement over the old formula. I think anyone who has tried Supremacy in the past, who then tries this; will be pleasantly surprised as well.

i hope so...i loved the original

[VaughnTrue]

do you plan on putting 6bromo back in once raws become available for most companies again?

[MBSowards]

do you plan on putting 6bromo back in once raws become available for most companies again?

This was a pretty old plan so I doubt it...

Oh yeah...

/inside info

[VaughnTrue]

This was a pretty old plan so I doubt it...

Oh yeah...

/inside info

looks like a nice change up

[XCriticalBenchX]

That was a beautiful post Alec!.


I got to check my bottles and see which formulas I have!

Mike

[-SDR-]

do you plan on putting 6bromo back in once raws become available for most companies again?

No, Micah is correct; this update has been on the drawing board for some time now. We were just making sure it was going to turn out at least as good as the 6-br version; and it is.

[MBSowards]

looks like a nice change up

I am all for it.