glutamine?

[epbody]

when is the best time to take Glutamine?

[BerkeleyBoy]

Best time to take it is:

Never: http://forum.bodybuilding.com/showthread.php?t=5607091

Glutamine isn't helpful

[Branch Chain Blink]

Best time to take it is:

Never: http://forum.bodybuilding.com/showthread.php?t=5607091

Glutamine isn't helpful

Current Supps:

Optimum Nutrition Whey
Optimum Nutrtion Casein
PrimaForce Creatine Mono
PrimaForce Beta Alanine
PrimaForce BCAA
BSN's NO-Xplode
Higher Power Glutamine



lol wut

[Simon Keller]

F-ing LOL...Repped...

[Miniswole]

lol

[BerkeleyBoy]

I guess i should take that out of my supps by now (this is the 2nd time I say glutamine is crap, and someone points out my sig)

I bought Glutamine a while back, before I did a lot of research on it. NOW after reading reseach on it, I think its worhless. This is the final tub of Glutamine I will ever own.

[in10city]

when is the best time to take Glutamine?

Why are you using it?

Falaciously expecting it to make you huge is one thing, but supplemental glutamine does have a beneficial role in general gut health, immune function, alleviating gastrointestinal disorders, and in elevating postpranial energy expenditure.

But unless you're busting your a$$ in the gym frequently or have immune or digestive support needs, don't count on it doing much ...

[pokerhard16]

Current Supps:

Optimum Nutrition Whey
Optimum Nutrtion Casein
PrimaForce Creatine Mono
PrimaForce Beta Alanine
PrimaForce BCAA
BSN's NO-Xplode
Higher Power Glutamine



lol wut

I'm not suprised by anything anymore,nice catch...funny sh*t.Blink is good people.

[infjspirit]

I'm not suprised by anything anymore,nice catch...funny sh*t.Blink is good people.

Glutamine aids in recovery...it's just not all what it's wrapped up to be, though.

You'll find it in many recovery supps, but alone you need to dose a whole bottle, basically


Don't buy bulk, is the point....

[emf]

most everywhere that you find articles on muscle repair,l glutamine is mentioned.
i train hard like most of you and at times couldn't distinguish between muscle soreness or the feeling that i may have pushed it to far.
i tried several glutamine products and got nothing out of them.
german american tech, glutamine peptides and mhp micronizes time release glutamine are two products that i use whichever is the best price.
i can def. tell that they work as my soreness is gone much sooner.
i also always double the amt. used and take it 3 times a day.
i spend a lot on supps. and have taken quite a few with no results but these two have helped me.

[2XL]

glutamine is worthless

brb, gotta take my glutamine

haha, seriously though, post-workout is best and then another scoop before bed

[Dr Nick]

Glutamine is proven worthless in muscle building and recovery etc but it could help boost your imune system:

Can glutamine modify the apparent immunodepression observed after prolonged, exhaustive exercise? Castell LM. Nutrition. 2002 May;18(5):371-5.

Glutamine is an important fuel for some cells of the immune system. In situations of stress, such as clinical trauma, starvation, or prolonged, strenuous exercise, the concentration of glutamine in blood is decreased, often substantially. In endurance athletes this decrease occurs concomitantly with relatively transient immunodepression. Provision of glutamine or a glutamine precursor has been found to decrease the incidence of illness in endurance athletes. To date, it has not been established precisely which aspect of the immune system is affected by glutamine feeding during the transient immunodepression that occurs after prolonged, strenuous exercise. However, there is increasing evidence that neutrophils may be implicated.

The relation between glutamine and the immunodepression observed in exercise. Castell LM, Newsholme EA. Amino Acids. 2001;20(1):49-61.

Glutamine is the most abundant amino acid in the body. It is an important fuel for some key cells of the immune system. Both the plasma concentration of glutamine and the functional ability of immune cells in the blood are decreased after prolonged, exhaustive exercise. Glutamine feeding has had beneficial effects in clinical situations, and the provision of glutamine after intensive exercise has decreased the incidence of infections, particularly of upper respiratory tract infections. However, the precise effect of glutamine on immunodepression in this situation is not yet established.

The effects of oral glutamine supplementation on athletes after prolonged, exhaustive exercise. Castell LM, Newsholme EA. Nutrition. 1997 Jul-Aug;13(7-8):738-42.

Athletes undergoing intense, prolonged training or participating in endurance races suffer an increased risk of infection due to apparent immunosuppression. Glutamine is an important fuel for some cells of the immune system and may have specific immunostimulatory effects. The plasma glutamine concentration is lower after prolonged, exhaustive exercise: this may contribute to impairment of the immune system at a time when the athlete may be exposed to opportunistic infections. The effects of feeding glutamine was investigated both at rest in sedentary controls and after exhaustive exercise in middle-distance, marathon and ultra-marathon runners, and elite rowers, in training and competition. Questionnaires established the incidence of infection for 7 d after exercise: infection levels were highest in marathon and ultra-marathon runners, and in elite male rowers after intensive training. Plasma glutamine levels were decreased by approximately 20% 1 h after marathon running. A marked increase in numbers of white blood cells occurred immediately after exhaustive exercise, followed by a decrease in the numbers of lymphocytes. The provision of oral glutamine after exercise appeared to have a beneficial effect on the level of subsequent infections. In addition, the ratio of T-helper/T-suppressor cells appeared to be increased in samples from those who received glutamine, compared with placebo.

Clinical applications of L-glutamine: past, present, and future.Wischmeyer PE. Nutr Clin Pract. 2003 Oct;18(5):377-85.

OBJECTIVE: This review will attempt to summarize recent clinical data on glutamine's use. It will present the concept of glutamine as a "drug" or "nutraceutical," given in addition to standard nutrition support. Key references will be discussed, and clinical recommendations with regard to patients who may benefit and dosing are also provided. Recent Findings: Glutamine, traditionally considered a nonessential amino acid, now is considered "conditionally essential" after critical illness, stress, and injury. States of illness or injury can lead to a significant decrease in plasma levels of glutamine, and when this decrease is severe, it has been correlated with increased mortality. Laboratory data have demonstrated numerous benefits of glutamine in experimental models of critical illness, cancer, and cardiac injury. The mechanism of these protective effects includes attenuated proinflammatory cytokine expression, improved gut barrier function, enhanced ability to mount a stress response, improved immune cell function, and decreased mortality. Over the last 10 years, clinical trials of glutamine supplementation in critical illness, surgical stress, and cancer have shown benefit with regard to mortality, length of stay, and infectious morbidity. However, data demonstrating a lack of benefit with glutamine supplementation in some patients have been presented as well. It appears that dose and route of administration clearly influence the benefit observed from glutamine administration, with high-dose parenteral glutamine demonstrating an advantage over low-dose enteral glutamine. SUMMARY: High-dose or parenteral (> 0.25 to 0.30 g/kg/day IV or >or=30 g/day enterally) glutamine appears to demonstrate the greatest potential for benefit in hospitalized patients. No evidence of harm has been observed in studies conducted to date; thus, further clinical trials using glutamine as a pharmacologic supplement to standard nutrition are warranted.

Glutamine in critical care: current evidence from systematic reviews. Avenell A. Proc Nutr Soc. 2006 Aug;65(3):236-41.

Glutamine, the most abundant amino acid in the body, is thought to become conditionally essential in critical illness. Some of the important roles for glutamine are as a carrier for inter-organ N, a preferred fuel for enterocytes and cells of the immune system, a substrate for renal NH3 formation and a precursor for glutathione. Mechanisms by which glutamine could improve recovery include attenuating oxidant damage and inflammatory cytokine production, reducing gut bacterial translocation and improving N balance. The present systematic review has found trends to suggest that parenteral and enteral glutamine supplementation reduce mortality, the development of infection and organ failure in critical illness. Trials of parenteral nutrition containing glutamine with patients after elective surgery also suggest reduction of infection, but it is unlikely that glutamine-containing parenteral nutrition would be used for such patients. The evidence base is limited by the quality of the reported trials and the suggestion that there is publication bias, with trials suggesting reduced infection being more likely to be published.

[Nailbomb9]

Glutamine is worthless!! Glutamine is worthless!! Well, you know what, maybe it is and maybe it isn't. Maybe it gives someone the mentallity to go out and bang em harder. And guess what else, "MOST" of supplements are prolly questionable and ****, but yet we still take them. If it gives someone a mental edge or what-not than I say go ahead and use it!!!

[Mack77]

Muscle growth/recovery aside.

Some guys have said it helps with digestion and the immune system. I get a TON of protein/day and have noticed that when I do not take the glutamine, the air can get pretty toxic for the ppl standing around me pretty fvkin quick. LOL

Is there any research online that anyone knows to support, or discredit glutamine helping with digestion/immune system function?

[StephanieShine]

Muscle growth/recovery aside.

It doesnt actually help your muscles grow directly. It improves recovery so you have better chances of making your muscle grow more on your own.

[Scottomus0]

its basically to help aid recovery.

i use it and it does actually help me.

everyone to there own i guess!