Chromium picolinate worse than i thought!

**Big_r** · 11-08-2005, 06:38 PM

Resistive training and chromium picolinate: effects on inositols and liver and kidney functions in older adults.
Thirty-two nondiabetic subjects, age 62 +/- 4 y, performed RT twice weekly for 12 wk and consumed either 924 ug Cr/d as Cr-pic (n = 17) or a placebo (n = 15). Whole-body strength increased in all subjects by 20 % (CR101).

Effects of resistive training and chromium picolinate on body composition and skeletal muscle size in older women.
Percent body fat and fat-free mass were unchanged with RT in these weight-stable women, independent of Cr-pic supplementation. Type I and type II muscle fiber areas of the m. vastus lateralis were not changed over time and were not influenced by Cr-pic supplementation (CR102).

Effect of chromium supplementation and exercise on body composition, resting metabolic rate and selected biochemical parameters in moderately obese women following an exercise program.
Twelve weeks of 400 microg/day of chromium as a CP supplement did not significantly affect body composition, RMR, plasma glucose, serum insulin, plasma glucagon, serum C-peptide and serum lipid concentrations or iron and zinc indices in moderately obese women placed on an exercise program. The changes in serum total cholesterol levels and TIBC were a result of the exercise program (CR103).

The effect of chromium picolinate on muscular strength and body composition in women athletes.
Fifteen women softball athletes were randomly divided into 2 groups, the chromium treatment group (n = 8) and the placebo control group (n = 7).
The CrPic supplementation consisted of a 500 ug dosage taken once per day. All participants trained 3 times per week with 2-3 sets of 8-12 repetitions at 80% of 1 repetition maximum (1RM) using variable resistance machines and free weights. No significant (p < 0.05) differences in muscular strength or body composition were found after 6 weeks of resistance training (CR104).

Effects of carbohydrate and chromium ingestion during intermittent high-intensity exercise to fatigue.
The data confirm an ergogenic benefit of ingesting CHO during exercise designed to imitate sports like basketball, soccer, and hockey, but do not support the hypothesis that the addition of Cr would enhance this effect (CR105).

Effect of resistance training with or without chromium picolinate supplementation on glucose metabolism in older men and women.
The effect of 12 weeks of resistance training (RT) with or without chromium picolinate (Cr-pic) supplementation on glucose tolerance was assessed in moderately overweight older men and women (age, 62 +/- 4 years; body mass index [BMI], 29.1 +/- 2.5 kg/m2).
High-dose Cr-pic supplementation had no effect on any measure of glucose metabolism during RT (CR106).

Effects of resistance training and chromium picolinate on body composition and skeletal muscle in older men.
18 men (age range 56-69 yr). The men were randomly assigned (double-blind) to groups (n = 9) that consumed either 17.8 micromol Cr/day (924 microg Cr/day) as CrPic or a low-Cr placebo for 12 wk while participating twice weekly in a high-intensity RT program.
High-dose CrPic supplementation did not enhance muscle size, strength, or power development or lean body mass accretion in older men during a RT program, which had significant, independent effects on these measurements (CR107).

Chromium picolinate effects on body composition and muscular performance in wrestlers.
Chromium picolinate supplementation coupled with a typical preseason training program does not enhance body composition or performance variables beyond improvements seen with training alone (CR108).

Chromium and exercise training: effect on obese women.
We conclude that high levels of chromium picolinate supplementation are contraindicated for weight loss in young, obese women (CR109).

Chromium supplementation and resistance training: effects on body composition, strength, and trace element status of men.
The effects of 8 wk of daily chromium supplementation (3.3-3.5 mumol as chromium chloride or chromium picolinate) or placebo (0.1 mumol Cr) and weight training were examined in 36 men in a double-blind design.
Routine chromium supplementation has no beneficial effects on body- composition change or strength gain in men (CR110).

Effects of chromium picolinate on body composition.
The study employed a double-blind, placebo-controlled protocol and lasted for 16 weeks.
400 micrograms chromium picolinate or a placebo were distributed to healthy, active-duty Navy personnel (79 men, 16 women).
chromium picolinate was ineffective in enhancing body fat reduction in this group (CR111).

Effects of chromium picolinate supplementation on body composition, strength, and urinary chromium loss in football players.
Chromium picolinate supplementation was ineffective in bringing about changes in body composition or strength during a program of intensive weight-lifting training (CR112).

Only the last study shows an effect from chromium picolinate on body weight in women but not men. Did this mean muscle or fat.........?

Effects of chromium picolinate on beginning weight training students.
Changes in body weight (BW), a sum of three body circumferences (sigma C), a sum of three skinfolds (sigma SF), and the one-repetition maximum (1RM) for the squat (SQ) and bench press (BP) were examined in 59 college-age students (37 males [M], 22 females [F]) over a 12-week weight lifting program. Using a double-blind protocol, half of the students were given 200 micrograms/day chromium (Cr) in the form of chromium picolinate (CrPic) while the other half received a placebo (P).
The only significant treatment effect found was due to the F-CrPic group gaining more BW (p = 0.0048) than the other three groups. It was concluded that CrPic supplementation had a greater effect on the females than on the males (CR113).

**CoQ10** · 11-08-2005, 07:20 PM

So....we shouldn't take chromium picolinate...?

**Bane** · 11-08-2005, 08:45 PM

Originally Posted by CoQ10

So....we shouldn't take chromium picolinate...?

Nope. Your multi is enough.

Great posting Big'R

**Big_r** · 11-08-2005, 08:47 PM

I think we finally found a supplement that's just as effective as the good ol' glutamine Bane.

**BringnIt** · 11-08-2005, 09:00 PM

Come on, it's not useless, just useless for bodybuilding.

**OMGitsMAX** · 11-08-2005, 09:07 PM

Glutamine helps with wound recoveries. I noticed it my self. I took it long ago when Ballys sold expired glutamine for 5$.
Chromium Picollinae safety; from http://www.supplementwatch.com/supli...templateId=100

Although the vast majority of studies of chromium supplementation reveal no side effects except mild gastrointestinal upset, they tend to be of short duration (a few weeks to a few months). Recent anecdotal reports, however, have suggested a variety of adverse side effects such as anemia, memory loss and DNA damage – in most cases for a particular form of chromium known as chromium picolinate. A handful of laboratory studies have shown that the supplemental form of chromium (chromium III) provided as the picolinate form, causes DNA breakage in isolated cells. Such DNA effects are thought to lead to genetic mutations and cancer, but it is important to note that these cell studies in the test tube are a long way removed from the case of a human ingesting an essential trace mineral. In one of the most publicized studies, Dartmouth researchers demonstrated that chromium picolinate is absorbed into cells intact (at least in the test tube), where it appeared to cause breaks in chromo****l DNA in hamster ovary cells (a common model for cancer researchers). The upshot of the study was that other chromium salts, such as nicotinate and chloride, were not taken up into the cells as efficiently as the picolinate version. There have been a few case reports of adverse effects following high dose chromium supplementation. In one, a 24-yr-old female body builder developed rhabdomyolysis, a serious condition causing muscle and kidney toxicity, after ingesting 1200 mcg of chromium picolinate over 48 hours. This is 6-24 times the daily recommended allowance of 50-200 mcg. Another case of toxicity following chromium picolinate ingestion (1200-2400 mcg for 4-5 months) involved a 33-yr-old woman who was taking it to enhance weight loss. The supplement increased blood chromium levels to 2-3 times normal and caused anemia, blood abnormalities, liver dysfunction, and renal failure. Both case reports demonstrate the fact that intakes of chromium picolinate at levels above the recommended dosage should be avoided. An animal study conducted by the USDA, fed rats a diet rich in chromium picolinate for 24 weeks and found no adverse side effects and there are no clinical studies that show harmful effects in humans from supplements containing chromium picolinate. It would seem prudent, however, to avoid excessive intake of supplements containing chromium picolinate and, where possible, select supplements which use alternate forms of chromium such as nicotinate, chloride or other amino acid chelates.

DNA DAMAGE!!! lol

**CoQ10** · 11-08-2005, 09:11 PM

Anyone wanna buy some chromium picolinate?

**Bane** · 11-09-2005, 08:13 AM

Originally Posted by Big'r

I think we finally found a supplement that's just as effective as the good ol' glutamine Bane.

Nope. Nothing beats good ol glutamine. Chromium costs 3 bucks and I haven't seen anyone who thinks it's the 4rth most important supplement.

**amjzzz** · 02-13-2006, 06:42 PM

Nice thread

**Shutup** · 02-13-2006, 11:37 PM

I have some 50 lb bags of chromium I use to kill bugs.

Should I stack it with glutamine to help the bugs with recovery?

**B.b. in stress!** · 02-14-2006, 12:29 AM

it was weird cause i once read a study that said taking 400 mcg a day helped lower the bf of individuals in a study. forget where its from though...

**Dia-Tribe** · 02-14-2006, 01:32 AM

Originally Posted by B.b. in stress!

it was weird cause i once read a study that said taking 400 mcg a day helped lower the bf of individuals in a study. forget where its from though...

I think that was as a result of the much earlier Chinese study...

Unfortunately even previously reported benefits for diabetics has been reviewed to - not recommended other than in special circumstances under medical supervision.

Check out this thread - link..
http://www.berkeleywellness.com/html/ds/dsChromium.php

**B.b. in stress!** · 02-14-2006, 07:16 PM

Originally Posted by Dia-Tribe

I think that was as a result of the much earlier Chinese study...

Unfortunately even previously reported benefits for diabetics has been reviewed to - not recommended other than in special circumstances under medical supervision.

Check out this thread - link..
http://www.berkeleywellness.com/html/ds/dsChromium.php

wow, i geuss chormium really does suck...

**TheSternMystic** · 02-14-2006, 07:36 PM

And of course it's a heavy metal, so I mean, Kidney/Liver failure, and the afformention destruction of DNA.

Basically, too much Chromium causes cancer.

**xven** · 02-15-2006, 10:22 AM

Anyone want to argue this one? I'm in total disbelief. So is everything that has been said about chromium, false?

**TheSternMystic** · 02-15-2006, 04:39 PM

Anything said about Chromium that is good, has been said by those who stand to gain. Only the supplement companies say it's good.

**Bane** · 02-15-2006, 06:24 PM

To put it more simply:If you are Chromium defecient(which if you take a multi you are propably not) chromium might be beneficial. Excess chromium however will only be bad for you.
Supplementation only holds merit when you are not getting enough of something

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**jmckiernan86** · 12-17-2011, 06:33 PM

Chromium picolinate is a questionable supplement at best, in my opinion.

**CastrenZ** · 12-20-2011, 11:47 PM

Originally Posted by jmckiernan86

Chromium picolinate is a questionable supplement at best, in my opinion.

I agree, the research just doesn't support it. The fact that are bodies only absorb around 2% of the total ingested dose make me wonder if it is actually harmful considering our body does a whole to prevent its absorption.

**LinDiva3** · 01-15-2012, 07:12 PM

Thanks for good info on this thread.

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