Primordial Performance Introduces: EndoAmp Max

[Adjusting]

What is EndoAmp Max?

EndoAmp Max is a naturally occurring phospholipid complex, designed to minimize the cortisol increase after exercise while amplifying the testosterone and growth hormone (GH) response.

As a mild "nutty" tasting powder, EndoAmp Max can be taken by itself or mixed with a beverage. Each dose includes 800mg of pure phosphatidylserine and 600mg of alpha-glycerylphosphorylcholine (A-GPC). At the recommended dose, EndoAmp Max will last 29 days.

EndoAmp Max is known as an "endocrine amplifier" because it can amplify the beneficial hormones such as testosterone & GH while preventing the unwanted spike in cortisol associated with exercise, so you can begin making progress towards building a harder, more masculine physique.



How does EndoAmp Max work?

EndoAmp Max works by supplying the body with vital phospholipids and neurotransmitters, thus reducing the requirement for cortisol following strenuous physical or mental activity and supporting higher testosterone and GH output. (11,21,37,38)

Increased GH and testosterone levels help promote faster recovery, increased muscle growth and enhanced fat loss. (36)



How does it support testosterone production?

The active ingredient phosphatidylserine (PS) prevents the exercise induced cortisol spike, and is a vital nutrient that supports testicular function and testosterone production. (11,37) Each serving of EndoAmp Max includes a clinically proven dose of 800mg of PS.

A recent study examined the effects of 10 days of 600mg/day PS supplementation on testosterone and cortisol during and after exercise. (37) The researchers found that PS supplementation increased testosterone 78% over the placebo group, while completely blunting the cortisol response to exercise. When analyzed for the testosterone to cortisol (T:C) ratio and compared to placebo, the PS group had a 3,354% higher T:C!

In another human study, hormone levels where examined during two weeks of intense weight training. The group receiving the 800mg of PS had higher testosterone levels and lower cortisol levels, compared to the group receiving the placebo. (11) Another study showed that 800mg of PS reduced cortisol levels 30% (compared to the placebo group) after intense cycling exercise. (21)

It?s been hypothesized that PS supplementation minimizes cortisol secretion by providing the necessary phospholipids required for cellular membrane structure and regulatory functions, thus reducing the requirement for bodily breakdown and nutrient displacement. (17,25,36,40)

Research also suggests that PS supports testosterone production by increasing the testes sensitivity to luteinizing hormone (LH) and increases testicular steroidogenesis - aka the creation of testosterone. (1-11, 19-26)

Take this quote from Cooke et al (1989) about the important role of PS in the testes ?

"The requirement for specific phospholipid configurations for optimal steroidogenic activity suggests a regulatory role for these membrane components. It is possible that certain phospholipids [phosphatidylserine] may possess the most suitable configuration and charge distribution to optimize the binding of the steroid substrate to the active site of the enzyme. Alternatively, they may assist the catalysis by providing a more suitable microenvironment or electrochemical gradient for proton transfer between enzyme and steroid."?

In other words, EndoAmp Max creates a more conducive environment for testosterone synthesis in the testes by mitigating the damaging effects from cortisol and supplying the testes with the necessary phospholipids for testicular function.



How does EndoAmp Max support Growth Hormone (GH) production?

The active ingredient alpha-glycerylphosphorylcholine (A-GPC) increases the synthesis and release of an important neurotransmitter known as acetylcholine which enhances GH production following exercise. (38-43) Each serving of EndoAmp Max provides a scientifically proven dose of A-GPC.

A recent study examined GH release in resistance trained men after supplementation with a single 600mg dose of A-GPC. When supplemented with A-GPC, GH levels peaked 68% higher than placebo following exercise. The peak bench press force was also 14% greater with A-GPC than placebo. (38)

Similar results have been found in another human study with young and elderly subjects. In the young subjects (30-34 yrs), A-GPC lead to a 40% higher increase in GH over the non-A-GPC group. In the elderly subjects (80-82 yrs.), A-GPC caused a 140% higher increase in GH over the non-A-GPC group. (39)

The research suggests that A-GPC amplifies the release of GH following growth-hormone-releasing-hormone (GHRH) stimulation. It was proposed that A-GPC supplementation increases acetylcholine levels in the brain, thus enhancing pituitary sensitivity and amplifying the release of GH from GHRH stimulation. (39)

Another mechanism by which A-GPC may increase GH secretion is by improving the fluidity of pituitary membranes, thus increasing signal transduction at the pituitary level. (39-41)

In laymen?s terms, EndoAmp Max increases the amount of GH secreted from exercise.



What sort of effects should I expect from EndoAmp Max?

Human research shows that EndoAmp Max can offer the following benefits

Improve the testosterone to cortisol ratio (11,21)
Amplify GH levels following exercise (38,39)
Increase resistance to stress & fatigue (19-23)
Increase exercise capacity (22, 38)
Speed recovery & reduce muscle soreness (23,24)
Enhanced sense of well-being (19,23)


Note: Although PS and A-GPC are naturally present in animal meat, most Americans are probably getting less than 120mg/day of PS & A-GPC combined through a Western diet (17,18,44). Therefore, supplementing with EndoAmp Max will ensure you get a sufficient amount of these highly valuable nutrients for the clinically proven benefits.



What are some signs that my cortisol is too high?

Excess fat distribution around the face and/or abdominal area (16)
Low Libido (33,34)
Low Testosterone* (2,3,10)
Low GH (Growth Hormone) (12-14)
Decreased insulin sensitivity (15)
Suppressed immune system (12, 15)
Mental depression (34)
Easily fatigued or exhausted (34,35)
Prolonged recovery from exercise (35)
*Cortisol dominance is a primary cause of hypogonadism and male impotence.

Keep in mind, it is normal and healthy to have elevated cortisol prior to waking from a night's rest, which is part of the body's natural regeneration process. However, it is not healthy to maintain elevated cortisol levels throughout the day.



What if I already have low cortisol? Will EndoAmp Max still benefit me?

Although seemingly contradictory, the answer is yes. Fortifying the body with the vital phospholipids and nutrients contained in EndoAmp Max will support the proper physiological structure & function of the body.

Remember, insufficient cortisol production is generally brought upon by adrenal fatigue which generally originates from over production of cortisol. In order to revive the adrenal glands and restore normal cortisol secretion, you must remove the hyper-cortisol stimulus, and reduce the requirement for cortisol by providing the body with proper nutrition.

What does it mean to ?reduce the requirement for cortisol??

Cortisol is a catabolic hormone produced by the body to breakdown bodily tissue and free up vital nutrients for the repair and maintenance of the body. (12)



Cortisol Secretion

1. When the brain senses a low availability of vital nutrients (e.g., glucose, phospholipids, etc.), it releases adrenocorticotropic hormone (ACTH) which travels down to the adrenal glands.

2. Once ACTH reaches the adrenal glands (above the kidneys), it stimulates the release of cortisol to begin breaking down bodily tissue. (12)

When muscle tissue is damaged during intense exercise it creates a high demand for nutrients (e.g., amino acids and phospholipids) for the structural repair of muscle tissue. Therefore, if the body is not supplied with sufficient nutrition to repair and rebuild the damaged cellular tissue, it will release cortisol to breakdown other areas of the body for the nutrients it needs.

Aside from breaking down muscle tissue for glucose and amino acids, research shows that cortisol also breaks down testicular tissue and reduces the body?s ability to produce testosterone, perhaps as a mechanism to free up phospholipid stores within the testes. (2-10)

Research with over-trained and/or malnourished athletes has clearly shown that high cortisol levels are associated with low testosterone levels. This is known as a low testosterone to cortisol ratio and is highly correlated with decreased performance, slow recovery and inability to gain lean body mass. (45,46)

Therefore, when the body is supplied with ample nutrients to repair itself, it reduces the requirement for cortisol.



Can I stack EndoAmp Max with other testosterone support supplements?

Yes, EndoAmp Max can enhance the effectiveness of other testosterone boosting supplements by amplifying the testes ability to produce testosterone.

This synergistic effect makes EndoAmp Max an important addition to our Testosterone Recovery Stack. It also makes EndoAmp Max a vital part of post cycle therapy (PCT), when preserving muscle mass and restoring natural testosterone production is of the utmost importance.

Supplement Facts
Serving Size 2200mg (one scoop)
Servings Per Container 29
Amount Per Serving %DV
----------------------------------------
SerinAid 1600mg*
----- Phosphatidylserine 800mg*
----- Phosphatidylcholine 154mg*
----- Phosphatidylethanolamine 128mg*
----- Phosphatidylinositol 68mg*
AlphaSize (A-GPC) 600mg*
(alpha-glycerylphosphorylcholine)

--------------------------------------

*Daily Value not established

[Adjusting]

References:

1. Identification and mechanism of action of phospholipids capable of modulating rat testicular micro****l 3 beta-hydroxysteroid dehydrogenase-isomerase activity in vitro
GM Cooke
Biol Reprod, Sep 1989; 41: 438 - 445.

2. Testosterone levels during systemic and inhaled corticosteroid therapy.
D Morrison, et al.
Respir Med, October 1, 1994; 88(9): 659-63.

3. Testicular function during prolonged corticotherapy
JM Kuhn, et al.
Presse Med, March 22, 1986; 15(12): 559-62.

4. Glucocorticoid Induces Apoptosis in Rat Leydig Cells
Hui-Bao Gao, et al.
Endocrinology, Jan 2002; 143: 130.

5. Role of glucocorticoid in the stress-induced suppression of testicular steroidogenesis in adult male rats.
Orr TE, Mann DR 1992
Horm Behav 26:350 ? 363

6. Suppression of endogenous corticosterone levels in vivo increases the steroidogenic capacity of purified rat Leydig cells in vitro.
Gao HB, Shan LX, Monder C, Hardy MP 1996
Endocrinology 137:1714 ? 1718

7. Mutually independent effects of adrenocorticotropin on luteinizing hormone and testosterone secretion
DR Mann, et al.
Endocrinology, Apr 1987; 120: 1542.

8. Reciprocal changes in plasma corticosterone and testosterone in stressed male rats maintained in a visible burrow system: evidence for a mediating role of testicular 11?Ÿ-hydroxysteroid dehydrogenase.
Monder C, et al.
Endocrinology 134:1193 ? 1198

9. The effect of stress-induced ligands on testosterone formation in Leydig cells.
Cooke BA, et al. 1992
West AP, eds. Stress and reproduction. New York: Raven Press; 135 ? 144

10. Acute suppression of circulating testosterone levels by cortisol in men.
Cumming D, Quigley ME, Yen SSC 1983
J Clin Endocrinol Metab 57:671 ? 673

11. HORMONAL EFFECTS OF PHOSPHATIDYLSERINE DURING 2-WKS OF INTENSE WEIGHT TRAINING
[Annual Meeting Abstracts]
Fahey, T. D.; Pearl, M.
California State University, Chico

12. Association of 24-Hour Cortisol Production Rates, Cortisol-Binding Globulin, and Plasma-Free Cortisol Levels with Body Composition, Leptin Levels, and Aging in Adult Men and Women
Jonathan Q. et al.
J. Clin. Endocrinol. Metab., Jan 2004; 89: 281 - 287.

13. Cortisol inhibition of growth hormone-releasing hormone-stimulated growth hormone release from cultured sheep pituitary cells
JL Sartin, et al.
J. Endocrinol., Jun 1994; 141: 517 - 525.

14. Lowering cortisol enhances growth hormone response to growth hormone releasing hormone in healthy subjects.
TG Dinan, J Thakore, and V O'Keane
Acta Physiol Scand, July 1, 1994; 151(3): 413-6.

15. Stress-Related Cortisol Secretion in Men: Relationships with Abdominal Obesity and Endocrine, Metabolic and Hemodynamic Abnormalities
Roland Rosmond, Mary F. Dallman, and Per Bjorntorp
J. Clin. Endocrinol. Metab., Jun 1998; 83: 1853 - 1859.

16. Visceral obesity: a "civilization syndrome".
Bjorntorp P
Obes Res. 1993 May;1(3):206-22.

17. Brain caphalin, a mixture of phosphatides. Separation from it of phosphatidyl serine, phosphatidyl ethanolamine, and a fraction containing an inositol phophatide.
Folch J et al.
J Biol Chem 1942 146(1):35-44

18. Food composition and nutritional tables.
Souci et al.
Medpharm Scientific Publishers; 200

19. The influence of phosphatidylserine supplementation on mood and heart rate when faced with an acute stressor.
Benton D et al.
Nutr Neurosci 2001, 4(3):169-178

20. Effects of phosphatidylserine on the neuroendocrine response to physical stress in humans.
Monteleone et al.
Neuroendocrinology 1990, 52(3):243-248

21. Blunting by chronic phosphatidylserine administration of the stress-induced activation of the hypothalamo-pituitary-adrenal axis in healthy men.
Monteleone et al.
Eur J Clin Pharmacol 1992, 42(4):385-388

22. Effects of phosphatidylserine on exercise capacity during cycling in active males.
Kingsley et al.
Med Sci Sports Exerc 2006, 38(I):64-71

23. The hormonal and perceptive effects of phosphatidylserine administration during two weeks of weight training-induced over-training.
Fayey TD, et al.
Biol Sport 1998, 15(2): 135-144

24. The effects of phosphatidyl serine on markers of muscular stress in endurance runners.
Fernholz et al.
Med Sci Sports Exerc 2000, 32(5):S321

25. Phospholipids and sports performance.
R Jager, et al.
J Int Soc Sports Nutr, Jan 2007; 4: 5

26. Effects of Phosphatidylserine on oxidative stress following intermittent running.
Kingsley M et al.
Med Sci Sports Exerc 2005 37(8):1300-1306

27. The effect of phosphatidylserine on golf performance.
Ralf Jager et al.
J Int Soc Sports Nutr. 2007; 4:23

28. Changes in Financial Strain Over Three Years, Ambulatory Blood Pressure, and Cortisol Responses to Awakening
Andrew Steptoe, Lena Brydon, and Sabine Kunz-Ebrecht
Psychosom Med, Mar 2005; 67: 281 - 287.

29. Perfectionism and the Cortisol Response to Psychosocial Stress in Men
Petra H. Wirtz, et al.
Psychosom Med, Apr 2007; 69: 249 - 255.

30. Influence of dietary protein, energy and corticosteroids on protein turnover, proteoglycan sulphation and growth of long bone and skeletal muscle in the rat.
ZA Yahya, et al
Clin Sci (Lond), Nov 1994; 87(5): 607-18.

31. Cortisol, testosterone, and free testosterone in athletes performing a marathon at 4,000 m altitude.
Marinelli et al.
Horm Res., 41(5-6), 225-229, 1994

32. Usefullness of free testosterone/cortisol ratio during a season of elite speed skating athletes.
Banfi et al.
Int J Sports Med., 14(7), 373-379, 1993.

33. Corticosterone Can Act at the Posterior Paraventricular Thalamus to Inhibit Hypothalamic-Pituitary-Adrenal Activity in Animals that Habituate to Repeated Stress
Azra Jaferi and Seema Bhatnagar
Endocrinology, Oct 2006; 147: 4917 ? 4930

34. Steroids and depression
Alexander Mitchell and Veronica O'Keane
BMJ, Jan 1998; 316: 244

35. Biological Markers of overtraining
Fahey et al.
Biol Sport 1997, 14:1-19

36. Amino acids and proteins for the athlete.
Di Pasquale
CRC Press, 2007, Pg 309

37. The effects of soy phosphatidylserine on cortisol, growth hormone and testosterone response to moderate intensity exercise.
Starks, et al.
University of Mississippi

38. Acute supplementation with alpha-glycerylphosphorylcholine augments growth hormone response to and peak force production during resistance exercise
Ziegenfuss et al.
J Int Soc Sports Nutr, Jun 2008 5(Suppl 1): P15

39. Alpha-Glycerylphosphorylcholine administration increases the GH response to GHRH of young and elderly subjects.
Ceda et al.
Horm Metab Res, Mar 1992; 24(3): 119-21.

40. Phospholipids as dynamic participants in biological processes.
Hanahan et al.
J lipid Res 1984, 25:1528-1535

41. Biosynthesis of phospholipids
Kennedy at al.
Fed, Proc 16: 847-853 (1957)

42. A multicentre trial to evaluate the efficacy and tolerability of alpha-glycerylphosphorylcholine versus cytosine diphosphocholine in patients with vascular dementia.
R Di Perri, G Coppola, LA Ambrosio, A Grasso, FM Puca, and M Rizzo
J Int Med Res, July 1, 1991; 19(4): 330-41.

43. Behavioral effects of L-alpha-glycerylphosphorylcholine: influence on cognitive mechanisms in the rat.
F Drago, F Mauceri, L Nardo, C Valerio, N Lauria, L Rampello, and G Guidi
Pharmacol Biochem Behav, February 1, 1992; 41(2): 445-8.

44. L--Glycerophosphocholine Contributes to Meat's Enhancement of Nonheme Iron Absorption
Charlotte N. Armah, Paul Sharp, Fred A. Mellon, Sandra Pariagh, Elizabeth K. Lund, Jack R. Dainty, Birgit Teucher, and Susan J. Fairweather-Tait
J. Nutr., May 2008; 138: 873 - 877.

45. Overtraining and elite athletes: Review and directions for the future.
Kuipers et al.
Sports Med. 1988, 6:79-92

46. Resistance exercise overtraining and overreaching neuroendocrine responses .
Kraemer et al.
Spots Med. 1997, 23(2):106-129

[Adjusting]

EndoAmp is currently listed on backorder, however it should be available for purchase soon.

http://www.bodybuilding.com/store/prim/endoampmax.html

Any questions? Post them if you got them.

[IKnowWhoYouAre]

this looks VERY VERY promising....price is steep though...is it cuz it's that much better?


1. any logs of it up?

2) is there any cortisol rebound?
3) how do you think it compares to LX/LFX/11-oxo/CEL's cortisol blocker?

[Adjusting]

this looks VERY VERY promising.

1. any logs of it up?

2) is there any cortisol rebound?
3) how do you think it compares to LX/LFX/11-oxo/CEL's cortisol blocker?

1. Not that I'm aware of on bb.com. You could search over at AM or our forum for more feedback.

2. No cortisol rebound whatsoever.

3. They work through different mechanisms. PS alters the T:C ratio from exercise induced stress...rather rapidly I might add.

[blumnblam]

Oh sweeet...

PTS + 600 mg A-GPC = very well played.

Does it matter when you dose it though? Would having it peri-workout be best? Or 4 hours after waking (when cortisol levels are highest, supposedly)

[Chimpinzo]

Cool product xD, I've been seeing it around before, but have always been a little touchy on picking it up based on price / lack of many comparable products.

How long would you say it would take to notice effects from supplementation?

[Adjusting]

Oh sweeet...

PTS + 600 mg A-GPC = very well played.

Does it matter when you dose it though? Would having it peri-workout be best? Or 4 hours after waking (when cortisol levels are highest, supposedly)

Post workout or in the morning sometime works best.

[Adjusting]

Cool product xD, I've been seeing it around before, but have always been a little touchy on picking it up based on price / lack of many comparable products.

How long would you say it would take to notice effects from supplementation?

You should notice less soreness and quicker recovery within a couple weeks. The effects keep building from that point on when you consider your T:C ratio and GH levels are changed favorably for as long as you use EndoAmp Max; not withstanding these phospholipids have a host of other benfits.

[Trauma1]

Oh sweeet...

PTS + 600 mg A-GPC = very well played.

Does it matter when you dose it though? Would having it peri-workout be best? Or 4 hours after waking (when cortisol levels are highest, supposedly)

I'd recommend dosing it early on in the day if possible. The mechanism here is to mitigate erratic fluctuations in the glucocorticoid cortisol over the course of the day maintaining a more therapeutic basal rate; as well as increase natural GH production. EmdoAmp Max is geared to limit those periods of excessive cortisol release which can translate into muscle tissue breakdown (limiting your gains and progress), and allow for a more homeostatic response toward potential muscle growth and prevention.

Killing off cortisol is not a good thing either as many people portray, and this is not what our product is doing. Cortisol serves useful in many ways; especially in terms of regulation of certain homeostatic factors and body systems. I plan to have a whole breakdown on cortisol eventually so everybody can easily understand what cortisol is, how it works, and what our product is doing in that regard.

[canecorso2009]

Primordial Performance EndoAmp Max=AWESOME!

[tastan]

Primordial Performance always makes something new a unique

[Adjusting]

Agreed guys!

[Trauma1]

Thanks for the support, guys!

[Trauma1]

Here's a good little addition to this thread:




Growth Hormone and Blood Sugar

The most important point in regards to growth hormone (GH) and diet is that "Growth hormone levels increase significantly when insulin levels are low" (Jamieson, p. 85). "More precisely, the cause of growth hormone inhibition is not high insulin levels but rather high blood sugar (which, because insulin is secreted to bring down blood sugar level, overlaps in time with high insulin levels)" (Faigin, p.201).

To explain further, "? glucose inhibits the secretion of growth hormone by acting on specific areas of the hypothalamus. Consequently, during the day, when food is consumed periodically, growth hormone secretion by the pituitary is suppressed, and insulin release by the pancreas is increased" (Dean).

But it should be noted that it is not just any food that causes a rise in blood sugar and the consequent insulin release, but primary carbohydrates. And some kinds of carbs cause a greater blood sugar increase than others. This issue is discussed in the article *The Glycemic Index.

I won't repeat all the details of that article here, but the important point is that low glycemic foods will not increase blood sugar as much as high glycemic foods. And eating a large amount of carbs at once will cause a greater increase in blood sugar levels than eating a small amount of carbs. Also, eating fat with carbs will blunt the rise in blood sugar.

What this means is, consuming a large amount of high glycemic carbs by themselves could completely halt growth hormone release. Or more generally, a high carbohydrate, low fat diet is absolutely devastating to growth hormone levels. This is one of the reasons why many people trying to lose weight on such a diet "plateau" after a period of time. Their inability to continue to lose weight is partly due to suppressed GH levels.

Moreover, a study comparing a group of boys consuming meals composed of high-glycemic index (GI) foods verses low GI foods found, "There were higher levels of the hormones insulin, noradrenaline, and cortisol after the high-GI meals" (Brand-Miller, p.230). So a rapid rise in blood sugar and insulin can lead to a rise in cortisol, with its attendant catabolic and lipogenic properties.

However, "? we need insulin to promote the benefits of growth hormone. Studies show that GH fails to cause growth in animals lacking a pancreas and it also fails if carbohydrates are restricted from the diet" (Jamieson, p.56). The reason for his could be that a strict low carb diet would lead to chronically low insulin levels, and insulin, as indicated above, is needed to drive amino acids into the muscle cells.

Moreover, IGF-1 is produced in the body through the combined actions of GH and insulin. And IGF-1 "? is at least as powerful an anabolic agent as either of its parents" (Faigin, p. 90). But a low carb diet would lead to a reduction in IGF-1 levels. So a low carb diet is not the answer either. In fact, this relationship of insulin, growth hormone, and IGF-1 is one reason why those following a low carb diet also often plateau after a period of time.

There is a relationship with thyroid hormone here as well. "Raising GH has a profound effect on normalizing thyroid function ? " (Jamieson, p.100). However, "Studies also show that diets that continuously restrict carbohydrate (like the Atkin's diet, for instance) cause a reduction in T3, and that administering carbohydrate can restore T3 levels after they have declined" (Faigin, p.139). This reduction in T3 is another reason people will often plateau on low carb diets.

So an ideal GH enhancing diet would include some carbs, but not an excessive amount. And the focus would be on low glycemic carbs.


Growth Hormone and Protein

Next to be considered is the relationship of GH to protein intake. "GH is released after the consumption of protein. This might signify to the body that it is now an opportune moment to build" (Creatine Newsletter).

Moreover, "Hormonally, protein intake is positively correlated with growth hormone, IGF-1, and glucagons. These hormones, collectively, exert an anabolic and lipolytic effect" (Faigin, p.156).

This article is about diet, not supplements. But the following paragraph would apply to raising GH levels via diet as well as via supplements:

People are curious why others get better results for their HGH supplementation. When we looked into why, we discovered that growth hormone supplementation increases the need for protein and people who supply the additional protein did better with their HGH supplementation program" (HGH Magazine, "Whey Protein").

So there is a synchronicity going on here. Increased protein intake will increase GH levels, and increased GH levels will increase the need for protein. Moreover, frequent protein feedings will increase absorption of protein and produce frequent GH spikes.

So an ideal GH raising diet would include frequent feedings of high quality protein.



This is the whole article if you're interested:

http://www.fitnessforoneandall.com/n...s/part_one.htm

[resistance1]

Anyone logging this stuff yet?

[Peter LeDrew]

Agree with the awesomeness of this product.

I just found this thread and a recent blood test showed I had elevated cortisol levels so I will put this to use soon.

[evankyle]

Agree with the awesomeness of this product.

I just found this thread and a recent blood test showed I had elevated cortisol levels so I will put this to use soon.

Peter which blood tests test cortisol levels?

[Peter LeDrew]

Peter which blood tests test cortisol levels?

http://www.webmd.com/a-to-z-guides/cortisol-14668

[Peter LeDrew]

Lets hear some feedback from this awesome product!




EndoAmp Max from Primordial Performance provides truely potent and quality forms of both Alpha-GPC and PS. It's rare to find this kind of formula in a bodybuilding product. No hiding behind a weak, cheap prop. blend here! This is exactly the kind of product that needs to be appreciated.

I will aim to post up some more studies in this thread as there are quite a comprehensive list of benefits from both ingredients here. EndoAmp uses the kind of science-backed doses the studies used.

Many products claim to be great against exercise induced cortisol increases, but few have actual studies backing them. Again, this is where Primordial shines! This should easily be a first choice weapon against cortisol... it is non-hormonal and will provide health benefits far beyond its effects against cortisol. Then don't forget the addition of 600mg Alpha-GPC in EndoAmp Max... simply awesome!




Seriously, do not take my (you may question my rep bias) word for it... check this study from the reputable Journal of the International Society of Sports Nutrition:
http://www.jissn.com/content/4/1/5


Don't want to read the entire thing? Here are some highlights for you. I highly suggest you read the entire thing to get a full appreciation for PS science.


Weight-Training
A 1998 study conducted at California State University investigated the effect of PS on hormone levels, muscle soreness and feelings of well-being when administered to experienced weight-trained athletes [37]. During the two-week training period, 11 weight-trained athletes (aged 22.8 ? 3.4 years) consumed either a placebo or 800 mg of S-PS per day (double-blind, cross-over design). The weight training program was designed to overtrain the subjects. Subjects were instructed to use as much weight as possible for each exercise and to train as hard as possible for 4 days a week during each 2 week training period. Subjective measures, such as perception of well-being and muscle soreness were recorded throughout the training period. Athletes had less muscle soreness when they were taking S-PS compared to the placebo (see figure 7).

Figure 7. PS supplementation significantly improves muscle soreness [37].

In addition, subjects had an improved perception of well-being when taking S-PS, this was particularly evident after the first week of training (see figure 8).

Figure 8. PS supplementation significantly improves well-being [37].



Phosphatidylserine has been demonstrated to be an effective supplement for combating exercise-induced stress and preventing the physiological deterioration that accompanies too much exercise (i.e. overtraining). Studies examining athletes involved in cycling, weight training and endurance running suggest that PS might speed up recovery, prevent muscle soreness, improve well-being, and might possess ergogenic properties. Under some circumstances, PS has been reported to suppress cortisol. This might protect muscle membranes against phospholipase damage, which is formed in response to muscle trauma. In addition, PS could increase the rate of glucose transported into muscle cells and, therefore, enhance recovery of muscle glycogen following strenuous exercise.

The effective dosages in sport studies range from 300 to 800 mg PS per day for short-term application (10 -15 days). The effective dosage for mental stress, which is closely related to physical stress, is 300 mg PS per day for 30 days. However, long-term studies on cognitive functions have found significant physiological effects using daily dosages as low as 100 mg PS per day. The lowest effective dose for athletes is unknown.

Many of the richest dietary sources of PC and PS are also high in cholesterol and fat. Egg yolk, meat and internal organs are good sources of phospholipids. Whereas grains, fruits and vegetables are relatively low in PC and PS. Modern Diets are depleted of phospholipids (primarily refined oils and fats, dehulled and cleaned raw materials). These changes in diet (low fat, low Cholesterol), as well as the BSE crises (mad cow disease), have led to a decrease in daily PS and PC consumption. Today's foods contain approximately one third of the phospholipid levels compared to the beginning of last century [7], which could increase the athletes need for proper nutrition and/or supplementation.



http://www.bodybuilding.com/store/prim/endoampmax.html


Whew, and that is just the tip of the iceberg with this product... you must consider the tremendous amount of postive research on Alpha-GPC which I will try and get into in time.

[Peter LeDrew]

Phosphatidylserine improves the body's hormonal response to training. The growing science is impressive.

http://www.pubmedcentral.nih.gov/art...rtype=abstract

Conclusion
The findings suggest that PS is an effective supplement for combating exercise-induced stress and preventing the physiological deterioration that can accompany too much exercise. PS supplementation promotes a desired hormonal status for athletes by blunting increases in cortisol levels.

Dose used was 600mg/day which provided a 35% increase in testosterone and a 35% decrease in muscle-wasting cortisol. The ratio between the two hormones improved by at least 180 percent!!


Now stop wasting money on cheaper, less proven and questionable products. EndoAmp Max provides an awesome formula of potent non-prop. dosed Alpha-GPC 600mg AND 800mg Phosphatidylserine. This is my new love as I love no-BS, science-backed ingredients at their clinically proven doses. That is a rare thing in this industry.


I'll repeat what the authors of the study concluded once more, PS supplementation promotes a desired hormonal status for athletes by blunting increases in cortisol levels.
That is exactly what we as bodybuilders are trying to do, achive that desired hormonal status to slowly build into a bigger, stronger, better body.

Now why isn't EVERYONE dosing this powdered goodness? If not, get on it NOW or stay puny, weak and overtrained forever!

http://www.bodybuilding.com/store/prim/endoampmax.html

[duffmt6]

my buddy just picked this up...ill let people know what he thinks

[Peter LeDrew]

my buddy just picked this up...ill let people know what he thinks

Smart bud. Love feedback on this stuff. Thanks.

[Trauma1]

Ralf Jager just gave a nice little review on Phospholipids and sports performance -

http://www.primordialperformance.com...rformance).pdf

[_Smitty_]

Ralf Jager just gave a nice little review on Phospholipids and sports performance -

http://www.primordialperformance.com...rformance).pdf

it's such a great contribution...

what's fascinating is that, due to PS pools being distributed 50:50 between the brain and the rest of the body, that PS supplementation not only aids in a physical performance capacity, but also in a mental performance one as well.

here's a link to the full article to accompany the presentation notes. i encourage anyone interested in phospholipid supplementation to have a look...

and pay strict attention to the final paragraph of the conclusion:

Many of the richest dietary sources of PC and PS are also high in cholesterol and fat. Egg yolk, meat and internal organs are good sources of phospholipids. Whereas grains, fruits and vegetables are relatively low in PC and PS. Modern Diets are depleted of phospholipids (primarily refined oils and fats, dehulled and cleaned raw materials). These changes in diet (low fat, low Cholesterol), as well as the BSE crises (mad cow disease), have led to a decrease in daily PS and PC consumption. Today's foods contain approximately one third of the phospholipid levels compared to the beginning of last century [7], which could increase the athletes need for proper nutrition and/or supplementation.

[Peter LeDrew]

it's such a great contribution...

what's fascinating is that, due to PS pools being distributed 50:50 between the brain and the rest of the body, that PS supplementation not only aids in a physical performance capacity, but also in a mental performance one as well.

here's a link to the full article to accompany the presentation notes. i encourage anyone interested in phospholipid supplementation to have a look...

and pay strict attention to the final paragraph of the conclusion:

Amazing stuff!!

I have been a fan of these ingredients in EndoAmp for a long time... like over 10yrs for PS and close on that long for A-GPC... the dosings and quality in EndoAmp is second to nice and an incredible value for those in the know... this is quite likely my favorite supplement in my huge supplement arsenal due to the comprehensive and proven benefits.

[bloodsimple1234]

very nice,has my attention for sure!

[Peter LeDrew]

very nice,has my attention for sure!

Starting to finally get some notice here. There are no hidden agendas or prop. blends here... simply potent dosings of two highly regarded nutrients in the nutraceutical industry in quality and trusted forms. There is tons of science out there if you look for it. pubmed is a great tool.

This is my personal pick for new product of the year. Unfortunately it hasn't sold enough on this site to make the bb.com awards list this year, but Pp is up for new brand of the year, so please take the time to vote for us and we'll take the time to come out with more effective formulas such as EndoAmp Max.

[Trauma1]

very nice,has my attention for sure!

Nice! Let us know if you have any specific product-related questions.

[MRB123]

Nice! Let us know if you have any specific product-related questions.

Thats what we do!!