In Beast's article ( http://www.bodybuilding.com/fun/beast11.htm ) he was saying leucine supplementation by itself throughs out of balance the BCAA's. His recommendation is to supplement with all 3 BCAA's, thereby preserving this balance.
05-25-2005, 08:09 AM #151
06-15-2005, 09:58 AM #152
06-15-2005, 11:02 AM #153
06-29-2005, 11:20 AM #154
06-29-2005, 11:55 AM #155
06-29-2005, 05:39 PM #156
06-29-2005, 05:55 PM #157
PU beings leucine is so cheap how about if one just took it as a supp and used regular whey if luecine is the key here. This would save some money. Any how, how many grams per day would one need to take. I am trying to find itOfficial Champion Performance Forum Rep
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06-29-2005, 05:57 PM #158
06-29-2005, 07:52 PM #159
07-12-2005, 11:50 AM #160Originally Posted by dmxinc
INDICATIONS AND USAGE
BCAAs may be helpful in a minority of patients with hepatic encephalopathy. There is preliminary evidence that BCAAs may prevent muscle catabolism and promote protein synthesis in some trauma subjects and, possibly, in some exercises. There is no evidence that they are effective for enhancement of athletic performance. Neither have they proved useful in treating amotrophic lateral sclerosis (ALS). In one trial, BCAAs reduced symptoms of tardive dyskinesia. They have also been used with some benefit in some with phenylketonuria.********
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07-13-2005, 08:49 PM #161
07-13-2005, 09:08 PM #162
07-13-2005, 09:08 PM #163Originally Posted by Sixpack
if you do that, wouldn't the body use protein and bcaa's to fuel your workouts?Interested in making an extra $3000+/month from home by working for a publically listed NYSE company? PM your e-mail or AIM address and we'll talk. U.S. Only.
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07-13-2005, 09:09 PM #164
07-13-2005, 09:11 PM #165Originally Posted by pu12en12g"I'm special, you're special. We are all just a bunch of special fcukers!" - Stifler
07-15-2005, 10:09 AM #166
07-22-2005, 09:40 AM #167
Sorry to bump this post, but I'd rather do this than create another one. I just purchased some bulk leucine and had a few questions:
1. How much should I take before workout and during?
2. How much should I take on my off days?
I am just a bit confused becuase, based on other threads/posts, it appears as if 50g of free form BCAA's a day should be the goal (from this post: http://forum.bodybuilding.com/showpo...4&postcount=10 ).
When I bought the bulk supply of this, I believe it was 100g for $5.00 or so. So basically, I will use 50g of that each day? So a kilo of bulk leucine will last 20 days ($50.00 for a kilo)? Wowzers....thats a budget killer if so (at least my budget.....wife wont like that! hehe).
Take care all..have a nice weekend!
Last edited by Baptizer; 07-22-2005 at 09:49 AM.
08-31-2005, 11:34 AM #168
08-31-2005, 11:41 AM #169
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09-07-2005, 09:18 AM #170
To add to this great discussion, I thought I would clarify something regarding a possible "imbalance" when megadosing leucine:
Originally Posted by 391rippy
Protein 23 g
L-Leucine 2470 mg
L-Isoleucine 1520 mg
L-Valine 1440 mg
Glutamine 3870 mg
L-Proline 1540 mg
L-Histidine 400 mg
Originally Posted by 391rippy
It was reported that feeding rats a leucine-rich diet decreases plasma concentrations of isoleucine and valine (10) and activates the hepatic BCKDH complex (11). This indicates that administration of leucine alone induces BCAA imbalance presumably because of inhibition of BCKDH kinase by KIC.
Notice how they reached that conclusion, and that a LOW PROTEIN diet was used:
High levels of dietary amino and branched-chain alpha-keto acids alter plasma and brain amino acid concentrations in rats.
Block KP, Harper AE.
Department of Biochemistry, College of Agricultural and Life Sciences, University of Wisconsin, Madison 53706.
Plasma and brain amino acid and plasma branched-chain alpha-keto acid (BCKA) concentrations were measured in rats fed diets containing high levels of individual amino and alpha-keto acids. Consumption of a low-protein (9% casein) diet high in leucine or alpha-ketoisocaproate depressed plasma concentrations of isoleucine and valine and their respective keto acids, alpha-keto-beta-methylvalerate and alpha-ketoisovalerate. High dietary levels of alpha-keto-beta-methylvalerate or alpha-ketoisovalerate (but not of isoleucine or valine) depressed plasma concentrations of the other BCKA and their respective branched-chain amino acids (BCAA). Consumption of a low protein, high phenylalanine diet depressed plasma concentrations of both BCAA and BCKA. Brain large neutral amino acid pools of rats fed all low-protein, high-amino acid diets were depleted. Consumption of diets high in individual BCKA increased brain concentrations of aromatic amino acids. In this study of rats allowed to feed for only 6 h/d, elevated brain phenylalanine concentration was associated with a significant depression of food intake, whereas elevated brain BCAA concentrations were not. Also, elevated plasma BCKA concentrations, comparable with those observed in maple syrup urine disease, were accompanied by elevations in concentrations of aromatic amino acids in brain but not in plasma.
09-27-2005, 08:37 PM #171
09-30-2005, 05:43 PM #172
10-01-2005, 10:40 PM #173
10-02-2005, 07:02 AM #174
10-02-2005, 07:22 AM #175
Leucine is the BCAA responsible for most of the effects we are looking for.....that is certainly true..
However, I personally would not take leucine by itself. The other two (isoleucine and valine) are most likely synergistic by other mechanisms. You need them for peptide hormone formation anyway (insulin, GH, etc)
Even the 2:1:1 ratio is "heavy" on the leucine compared to what you normally find in protein. Whey protein has the highest leucine ratio (1.6 :1 :1), but even it is not 2:1:1.
Originally Posted by pu12en12g
Later on I'll try to pool some theories/mechanisms together on how the others work together with leucine. (I haven't read this thread entirely yet so some of it might already be in here) I'll probably add it to this thread---->http://forum.bodybuilding.com/showthread.php?t=578950
Last edited by Phosphate bond; 10-02-2005 at 08:11 AM.
10-15-2005, 01:26 PM #176
11-01-2005, 09:48 PM #177
11-01-2005, 10:01 PM #178
You're a dirty topickickerWhich SUPPLEMENTS do i use PRE/POSTWORKOUT:
The effects of ANTI-E'S and AI'S on the axis and gyno:
MILK THISTLE info:
11-09-2005, 01:57 PM #179
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i just got 700grams total of bcaa's from 2 bottles for 25$, and am interested in megadosing, but im 145lb with 9%bf, so, from what i heard, 20% of your lean body mass should be how many grams you should take for mega dosing, so it would be about 25-30grams for me. MOST of bcaas ingested are supposed to be taken before, during and after a workout, so do you suggest i take 25-30 grams only on workout days, (7.5g in the morning and at night, 5g before and after workout, and 10g during or 2/3 through a workout. I do HST currently, so would do that 3x a week. do you suggest i continue to take 25-30 grams on off days, because i tend to do cardio from ddr for fun and to keep from gaining fat from my bulk, and take some bcaas then, or 10-15grams of bcaas on off days, and what about weekends? Keep in mind just because im mega dosing doesnt mean i dont want to ration. thanks!NPTI Certified PT
11-18-2005, 05:44 AM #180