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    up the dosage eatyourspinach's Avatar
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    Epicatechin and exercise performance

    Acute (-)-Epicatechin Consumption: Effects on Local Vasodilation Following Resistance Exercise and High-Intensity Exercise Performance

    Abstract: (-)-Epicatechin is a polyphenol previously shown to enhance vascular health. The purposes of the current studies were to determine the effect of acute (-)-epicatechin supplementation on local vasodilation in conjunction with resistance exercise (study 1) and on high-intensity exercise performance (study 2). For study 1, 11 men participated in two resistance exercise sessions, where they performed three sets of barbell curls while consuming 200 mg of 98% pure (-)-epicatechin or placebo. Measurements of total serum nitrate/nitrite and brachial artery diameter were acquired at baseline (pre-supplement), 90 min after supplement consumption (post-supplement), immediately post-exercise (post-exercise), and 30 min post-exercise (30 min post-exercise). For serum nitric oxide metabolites, no significant interaction between supplement and time nor significant main effect of time was observed (p = 0.38 and p = 0.20; respectively). For brachial artery diameter, no significant interaction between supplement and time was observed (p = 0.24). A significant main effect of time was observed for brachial artery diameter (p < 0.01) with post-exercise brachial artery diameter significantly greater diameter than all other time points (all p < 0.01). For study 2, six women and five men completed the 15.5 CrossFit® Open Workout three times. A familiarization session was performed first where the workout was performed without the consumption of a supplement. In a randomized, balanced fashion, 100 mg of 98% pure (-)-epicatechin or cellulose (placebo) was consumed two times per day for two days before testing sessions two and three. On the day of testing sessions two and three, 60 to 90 min before completing the workout, 200 mg of the assigned supplement was ingested with water. No significant difference was observed for time to complete the workout between testing sessions (p = 0.49). In conclusion, under the conditions of the current studies, acute (-)-epicatechin supplementation did not augment vasodilation in combination with resistance exercise, nor did it increase exercise performance in humans.


    https://www.mdpi.com/2075-4663/8/2/22/htm
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    in10city stalker Madevilz's Avatar
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    up the dosage eatyourspinach's Avatar
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    Originally Posted by Madevilz View Post
    It makes me irrationally angry when I see supplements with 750 mg Nitrosigine per dose even though 1.5 g is studied
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    in10city stalker Madevilz's Avatar
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    Originally Posted by eatyourspinach View Post
    It makes me irrationally angry when I see supplements with 750 mg Nitrosigine per dose even though 1.5 g is studied
    I know lol. Or worse, Ive seen a few at 1g. Like... couldn't they afford to put 500mg more?
    Just like supplements with 3g of citrulline or 5g of CM. Even 6g of CM is too low in my book.
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    Registered User OT2000's Avatar
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    My only thoughts on this study, epicatechin is an antioxidant. I don’t see the point in trying pwo. Second I thought it has terrible bioavailability?
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    Registered User AMeyer9's Avatar
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    Originally Posted by OT2000 View Post
    My only thoughts on this study, epicatechin is an antioxidant. I don’t see the point in trying pwo. Second I thought it has terrible bioavailability?
    I believe its source makes a big difference. When I was with an unmentioned company and they switched sources to green tea epi and it definitely wasn't as good.
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    Rustlin' and hustlin' poison's Avatar
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  8. #8
    up the dosage eatyourspinach's Avatar
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    Originally Posted by OT2000 View Post
    My only thoughts on this study, epicatechin is an antioxidant. I don’t see the point in trying pwo. Second I thought it has terrible bioavailability?
    The same logic as Vaso6 and Spectra

    Originally Posted by poison View Post
    Whhere was it from before the switch?
    cocoa I think
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    Registered User OT2000's Avatar
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    Originally Posted by eatyourspinach View Post
    The same logic as Vaso6 and Spectra



    cocoa I think
    Neither did anything for me
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    Originally Posted by eatyourspinach View Post
    It makes me irrationally angry when I see supplements with 750 mg Nitrosigine per dose even though 1.5 g is studied
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