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  1. #1
    up the dosage eatyourspinach's Avatar
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    Anti-Alzheimer's effect of caffeine

    The effects of caffeine on concentrations of amyloid-beta proteins in late-onset Alzheimer’s disease were investigated. Data was collected through a systematic literature review. Results of a statistical analysis produced a negative correlation between the concentrations of caffeine and amyloid-beta, suggesting that caffeine may play a role in reducing plaques in patients with late-onset Alzheimer’s disease.

    Alzheimer’s disease is a neurodegenerative disease affecting six million Americans today. It is a leading cause of death and has no apparent cure. The disease is characterized by neuron death arising from amyloid-beta protein plaques, preventing nerve communication and signaling in the brain. Caffeine, C8H10N4O2, is an extracellular particle that expresses a signaling pathway through molecular antagonism. It has been shown to reduce amounts of harmful proteins in the brain, which may apply to Alzheimer’s disease because its plaques are made of toxic amyloid-beta 1-42 and 1-40 proteins.

    A systematic literature review was conducted for this study. The electronic bibliographic databases EBSCOhost, Google Scholar, PubMed, ResearchGate, Cochrane Library, JSTOR, and AAAS were used to collect literature. Quantitative data testing the effects of caffeine on the presence of amyloid-beta 1-40 and 1-42 proteins was compiled. The results were then studied, recorded, and analyzed with statistical testing

    http://jkswanson.com/STEM19Poster14.pdf

    http://jkswanson.com/STEM19Poster14.pdf
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  2. #2
    Rustlin' and hustlin' poison's Avatar
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