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  1. #1
    Registered User Treestoneface's Avatar
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    Question Negative Effects of Yohimbe/Yohimbine on Reproductive health

    Has anyone read this paper (cant link to it not enough posts) its titled something like " Adverse effects of prolonged use of P. Yohimbe on reproductive health ".

    This study was done on rats so I'm not sure if they are taking absurd doses and if I should be concerned or not,one group was taking 150mg/kg and the other was 300 mg/kg of yohimbe. I believe yohimbe extract is about 9% yohimbine so this would be 13.5 mg and 27mg of yohimbine I believe. as of now I have stopped taking my yohimbine hcl. I was only taking about 10mg a day spaced out in multiple doses while intermittent fasting.

    It says it doesnt effect hormonal health but does negatively affect testosterone/E2 ratio.

    It also says it has deleterious effects on testis/seminal vesicles. This sounds generally not great lol and the pictures look like the testis/vesicles are just turning into mashed potatoes. Let me know if you have any knowledge or experience on the subject. I was enjoying taking it and having some noticeable fat loss.

    Thank you!
    Last edited by Treestoneface; 01-13-2020 at 08:31 AM.
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  2. #2
    up the dosage eatyourspinach's Avatar
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    150 mg/kg for a 90 kg person would be 13,500 mg wouldn't it?
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  3. #3
    Registered User Treestoneface's Avatar
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    Originally Posted by eatyourspinach View Post
    150 mg/kg for a 90 kg person would be 13,500 mg wouldn't it?
    Yeah I think a rat weighs like 500 grams lol. So the dose is huge for a rat. When it comes to my reproductive system I'm very protective lol. I suppose if it was a issue people would be reporting problems.
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  4. #4
    MANwhore mtpaquette's Avatar
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    Average weight for a rat would be roughly 226grams. I'm guessing around 35g of yohimbe not yohimbine?
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    Verified Aesthetic rhadam's Avatar
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    I’ve skimmed that paper, no relevance for humans at this time.
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    Registered User hurley4health's Avatar
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    Likely not negative unless too high of a dose is taken. It will vary per individual as well.
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