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    CoQ10 worth supplementing with?

    Coenzyme Q10 status, glucose parameters, and antioxidative capacity in college athletes

    Abstract
    Background

    Glycemia is related to energy production during exercise. Coenzyme Q10 is an antioxidant that participates in adenosine triphosphate synthesis in mitochondria. The aim of this study was to investigate the level of coenzyme Q10, glucose parameters, and antioxidant capacity in athletes.
    Methods

    This study was designed as a cross-sectional study. Well-trained college athletes (n = 43) and age-gender matched healthy subjects (n = 25) were recruited from a college. The levels of glucose parameters, oxidative stress, antioxidant enzymes activity, Trolox equivalent antioxidant capacity (TAC), and coenzyme Q10 status were measured in the present study.
    Results

    The athletes had a significantly lower level of white blood cells (WBC) coenzyme Q10 than the healthy subjects (0.34 ± 0.24 vs. 0.65 ± 0.43 nmol/g, p < 0.01); however, no significant difference was detected in plasma coenzyme Q10 between the two groups. Regarding the glucose parameters, the athletes had significantly higher values for HbA1c (5.5 ± 0.3 vs. 5.3 ± 0.3%, p < 0.05) and quantitative insulin sensitivity check index (QUICKI, 0.37 ± 0.03 vs. 0.34 ± 0.03, p < 0.05), and lower homeostatic model assessment-insulin resistance (HOMA-IR, 1.5 ± 0.8 vs. 2.9 ± 3.8, p < 0.05) than the healthy subjects. A higher level of TAC was found in the athletes (serum, 5.7 ± 0.3 vs. 5.4 ± 0.2 mM Trolox; erythrocyte, 10.5 ± 0.6 vs. 10.0 ± 0.5 mM Trolox, p < 0.05). In addition, WBC coenzyme Q10 status was significantly correlated with catalase activity (r = 0.56, p < 0.01), GPx activity (r = 0.56, p < 0.01), serum TAC (r = 0.54, p < 0.01), fasting glucose (β = − 1.10, p < 0.01), HbA1c (β = − 0.82, p < 0.01), HOMA-IR (β = − 1.81, p < 0.01), and QUICK (β = 0.08, p < 0.01).
    Conclusions

    Athletes may suffer from a marginal coenzyme Q10 deficiency, and the level was related to glycemic control and antioxidant capacity. Further interventional studies are needed to clarify an adequate dose of coenzyme Q10 supplementation in athletes to optimize their coenzyme Q10 status and athletic performance or recovery during exercise.

    "Previous studies have observed that athletes may suffer from coenzyme Q10 deficiency due to sustained heavy physical exertion . Athletes may exhibit a lower coenzyme Q10 status because they have high metabolic requirements; coenzyme Q10 may be depleted during exercise as a result of energy metabolism and limit athletic performance...A high coenzyme Q10 status may enhance the peak power production of athletes [27, 29]. In this study, athletes without supplementation showed a low marginal coenzyme Q10 status, and adequate supplementation to improve their coenzyme Q10 status should be assessed."



    https://jissn.biomedcentral.com/arti...20-0334-3#Abs1

    Anecdotally I can say I from previous experience taking Ubiquinol I did feel like recovery was better but not enough to justify the cost and I don't know if it was relevant to this but does anyone take CoQ10 or Ubiquinol?
    Last edited by eatyourspinach; 01-10-2020 at 06:32 PM.
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