Arguments on Artificial Sweetener affecting Insulin Levels.

[lockhrt999]

I don't know why but I find most of the research on artificial sweeteners is very confusing/baised.

1. Research says that artificial sweeteners increase insulin levels just like regular sugar. I can understand that brain is making pancreas release insulin in anticipation that the body maybe going to receive heavy dose of carbohydrate.

2. So if that's the case then shouldn't the unnecessarily released insulin shuffle whatever blood glucose in the cells? Shouldn't that indirectly cause low blood sugar? because there are no real carbohydrate were consumed to justify the increased insulin.

3. Granted your liver will release stored glucose to balance blood sugar but again it has limited stock. If you're in keto, deprived of most of the carbohydrate, your liver doesn't have glucose left to balance your blood sugar. So using artificial sweeteners in keto means you must get low blood sugar and it should give you its symptoms. Low blood sugar make you very hungry, it makes you crave sweet food and it makes you lethargic.

4. But those symptoms are absent. Using artificial sweeteners doesn't make me more hungry or lethargic.

5. On deep keto, people can take black coffee with artificial sweeteners and do fasting for whole day and still don't get hungry. (fasting is very easy on keto, if you didn't know).

6. If above logic is sound then the research doesn't make any sense.

7. If research is saying artificial sweeteners should empty your liver glucose store faster. Isn't that very outcome highly desired by the people who are doing carb cycle/low carb/keto diet? If the research is saying that artificial sweeteners makes your liver release glucose then how's that not like doing cardio? We are doing the same thing on cardio, emptying glucose storage so that body can go on fat burning phase.

8. If you just use artificial sweeteners and avoid sugars for many years, Shouldn't body learn to not to release insulin just because our taste buds tasted something sweet. Maybe it'll start expecting food to be present in the digestion tracks first. We are feeding our children food which is very sugary. But we replace that sugar with artificial sweeteners, shouldn't body develop ability to not to release insulin only because the child tasted something sweet in its mouth?

9. This particular research was done on 17 people only. And only half of them were on artificial sweeteners. It's too small research scale to consider it. Plus you should also consider that sugar lobby is one of the biggest in the US and they'll do anything to destroy anything that comes against the sugar. They did that to saturated fats and cholesterol previously.

10. So guys what am I missing from this picture? Is there a problem with my logic or research has some fallacies in it?

[MrCarrot]

I always wondered why it mattered if artificial sweetener increased insulin when it's virtually zero calories. Because the insulin would have nothing to carry in to fat storage. That is, unless you drink a diet soda along with eating some other carbs that wouldn't ordinarily be shuttled into fat storage, but are due to increased insulin. I don't know whether that's really a thing though.

[rtpmarine]

Artificial sweeteners definitely hijack the cephalic phase of digestion--there is no doubt about that. Whether or not that is a bad thing really just depends on what you need to do:

• If you are obese and living life chronically overfed, with glycogen stores filled up, then yeah it's bad because the insulinemic response is going to have plenty of substrate to push into adipose tissues.
  
• For lean people the effect could be a good thing depending on how well it is used strategically. Remember, lean people on a diet get very efficient at burning fatty acids. One of the first things that insulin does, loooooong before it triggers glucose uptake anywhere in the body, is it tells the adipose tissues to stop breaking down fat (known as lipolysis) because it's expecting an increase of glucose. This mitigation of lipolysis can be helpful to a lean person who is on a diet, because it allows a brief up-regulation of the metabolic processes that execute lipolysis. Think of it like giving the factory workers a break--when they get back to work they'll be refreshed.

Insulin gets such a bad rap because most people live life happily hyperglycemic, hyperinsulinemic, and ever-more insulin resistant. But that doesn't mean that our metabolic reactions to insulin are innately good or bad, they just can't be abused. If you are eating and exercise according to a healthy lifestyle, then artificial sweeteners will make a negligible impact to your health.

#8 Want to address this one in particular, because it's actually the opposite that happens. Sugar is highly addictive and the cephalic response will grow much stronger as the addiction is fed. Whether you feed the addiction with sugar or with artificial sweeteners isn't going to change the effect. This is one of the reasons keto works so well for people who are obese and sugar-addicted. It breaks the addiction and puts your brain back in balance so that your body can deploy the natural defense mechanisms that stop you from overeating.

[Mrpb]

Throughout development of sucralose (commercially known as Splenda) as a sweetener, more than 100 studies have been conducted to assess its impact on physiology & safety, including its potential to affect glycemic control & insulin (US HHS FDA, 1988)⁣.
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Review of these studies led to regulatory confirmation of sucralose safety, including for persons with diabetes. Still, many self proclaimed ‘experts’ claim that artificial sweeteners like sucralose can cause fat gain by increasing insulin.
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A study by Lee Grotz et al 2017 (double-blind, parallel, randomized clinical trial) examines this claim specifically. ⁣
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The study consisted of 3 phases: 4 week screening, 12 week test,⁣
and 4 week follow-up. During the test phase, volunteers were supplied, weekly, with bottles of capsules containing either ~333 mg sucralose (28 packets/day) or placebo (cellulose) and instructed to take with meals 3x/day to mimic common timing for sweetener consumption.⁣
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The average daily intake of sucralosewas 13.2 mg/kg/day⁣ based on the daily sucralose dose (1000 mg/day) and volunteer body weight.⁣
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They found NO DIFFERENCES between sucralose and⁣ placebo groups in mean baseline HbA1c, fasting glucose, C-peptide, or insulin at ANY test visit (visits 1- 12) or at follow up visits ⁣
⁣
So the TAKEAWAY here is still consistent with other studies, and it seems like the collective evidence supports that sucralose has no effect on glycemic control or insulin levels...⁣

Source Layne Norton on ********: https://www.********.com/LayneNorton...o5bA&__tn__=-R