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10-24-2017, 12:14 PM #31
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10-24-2017, 10:52 PM #43
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10-25-2017, 07:35 AM #44
https://www.ncbi.nlm.nih.gov/pubmed/20643105
R-(-)-beta-O-methylsynephrine, a natural product, inhibits VEGF-induced angiogenesis in vitro and in vivo.
Kim NH1, Pham NB, Quinn RJ, Kwon HJ.
Author information
Abstract
R-(-)-beta-O-methylsynephrine (OMe-Syn) is an active compound isolated from a plant of the Rutaceae family. We conducted cell proliferation assays on various cell lines and found that OMe-Syn more strongly inhibited the growth of human umbilical vein endothelial cells (HUVECs) than that of other normal and cancer cell lines tested. In angiogenesis assays, it inhibited vascular endothelial growth factor (VEGF)-induced invasion and tube formation of HUVECs with no toxicity. The anti-angiogenic activity of OMe-Syn was also validated in vivo using the chorioallantonic membrane (CAM) assay in growing chick embryos. Expression of the growth factors VEGF, hepatocyte growth factor, and basic fibroblast growth factor was suppressed by OMe-Syn in a dose-dependent manner. Taken together, our results indicate that this compound could be a novel basis for a small molecule targeting angiogenesis.I got no strings to hold me down
To make me fret or make me frown
I had strings, but now I'm free
I got no strings on me
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10-25-2017, 08:55 AM #45
- Join Date: Feb 2003
- Location: Ephrata, Pennsylvania, United States
- Posts: 24,588
- Rep Power: 283695
He hasn't competed *yet* but I think he will in the very near future. My daughter does compete however in Powerlifting. She is on the powerlifting team at Penn State right now.
My son will do Bodybuilding (I would think) and probably Juniors in the next 2-3 years. So at that time, I'll probably train for the show with him. Whether I throw the man thong on and hit the stage is still to be determined, lol
-Spaz
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10-25-2017, 11:45 AM #46
Hoping for someone that buys this to give feedback on it as I'm pretty interested in making a purchase.
Also, do you think that hi tech is also going to make the switch in off-the-chain? As in replacing DMAA with senegalia?-MAN Sports Representative -
Disclaimer: The statement above reflects that of my own opinion and in no way that of MAN Sports. Our products are not intended to diagnose, treat, cure, or prevent any disease.
www.instagram.com/damonphysique
CLEAN PROTEIN is HERE on bodybuilding.com!
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10-25-2017, 11:50 AM #47
- Join Date: Feb 2013
- Location: New York, New York, United States
- Age: 43
- Posts: 16,991
- Rep Power: 91765
Completed Logs & Reviews:
Clear Muscle Log: http://forum.bodybuilding.com/showthread.php?t=161906833&p=1244983053#post1244983053
"Now that you've got a basic degree of strength you can now proceed with success onto a bodybuilding type program - which I am not experienced in providing. You've exceeded what I focus on, and that is beginner strength gains." - Mark Rippetoe
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10-25-2017, 11:53 AM #48
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10-25-2017, 11:54 AM #49
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10-25-2017, 11:55 AM #50
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10-25-2017, 12:06 PM #51
- Join Date: Feb 2013
- Location: New York, New York, United States
- Age: 43
- Posts: 16,991
- Rep Power: 91765
What I posted earlier was in regards to Meso btw for the record :P
Completed Logs & Reviews:
Clear Muscle Log: http://forum.bodybuilding.com/showthread.php?t=161906833&p=1244983053#post1244983053
"Now that you've got a basic degree of strength you can now proceed with success onto a bodybuilding type program - which I am not experienced in providing. You've exceeded what I focus on, and that is beginner strength gains." - Mark Rippetoe
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10-25-2017, 12:09 PM #52
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10-25-2017, 12:11 PM #53
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10-25-2017, 01:59 PM #56
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10-27-2017, 02:05 PM #57
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10-27-2017, 05:01 PM #58
- Join Date: Aug 2014
- Location: New York, United States
- Posts: 10,855
- Rep Power: 154465
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05-01-2018, 07:59 PM #59
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05-02-2018, 03:41 AM #60
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