https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3642442/
Many active compounds have been isolated, identified and reported so far in different varieties of black seeds. The most important active compounds are thymoquinone (30%-48%), thymohydroquinone, dithymoquinone, p-cymene (7%-15%), carvacrol (6%-12%), 4-terpineol (2%-7%), t-anethol (1%-4%), sesquiterpene longifolene (1%-8%) α-pinene and thymol etc. Black seeds also contain some other compounds in trace amounts. Seeds contain two different types of alkaloids; i.e. isoquinoline alkaloids e.g. nigellicimine and nigellicimine-N-oxide, and pyrazol alkaloids or indazole ring bearing alkaloids which include nigellidine and nigellicine. Moreover, N. sativa seeds also contain alpha-hederin, a water soluble pentacyclic triterpene and saponin, a potential anticancer agent.
Anti-inflammatory and analgesic activity
"Osteoporosis has been linked to oxidative stress and inflammation. The studies on the anti-osteoporotic effects of N. sativa and TQ were carried out. It was revealed that N. sativa and TQ were shown to inhibit inflammatory cytokines such as interleukin-1 and 6 and the transcription factor, nuclear factor κB. Both NS and TQ have shown potential as anti-osteoporotic agent."
Gastro-protective activity
"Besides the antioxidant property, TQ has novel gastroprotective mechanisms via inhibiting proton pump, acid secretion and neutrophil infiltration, while enhancing mucin secretion, and nitric oxide production."
Neuro-pharmacolgical activities
"The aqueous and methanol extracts of defatted N. sativa L. seeds were shown to possess a potent central nervous system and analgesic activities, especially depressant action in the case of the methanolic extract[104]. An anxiolytic drug acts by increasing the 5-HT and decreasing the 5-HIAA (hydroxyindole acetic acid) levels in brain. A long term administration of N. sativa increases 5-HT levels in brain and improves learning and memory in rats[105]. Repeated administration of N. sativa decreases 5-HT turnover and produces anxiolytic effects in rats."
Consider my anecdotal evidence as for what it's worth but these are three aspects in which I can say I have noticed a difference since I've been taking it regularly for two months.
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Thread: Black Seed Oil
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05-12-2017, 12:55 PM #1
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Black Seed Oil
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