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  1. #421
    Registered User ShahShahanshah's Avatar
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    Question Natural Creatine Production

    Greetings everybody,
    I have been considering implementing some Creatine Monohydrate into my Supplement line-up, and I have been wondering if taking supplemental creatine can affect your muscles' natural creatine production.
    Just in case I decide to lay off CM after a while
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  2. #422
    Registered User kingofturtles's Avatar
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    Id just like to ask a clarifying question. From what I understand:

    Your body has 3 seconds of ATP stores. After that is depleted it uses CP to make more ATP. Your body has 15 seconds of CP stored (then your body turns to glycogen to make ATP). After that you need to rest 2-5 mins to restore everything.

    What exactly does creatine supplementation help with? Does it raise the initial "stored" CP? So instead of 15 seconds of CP (for a total of 18 seconds) you get, maybe 20 seconds of CP?

    Or does it change the amount of times you can recharge after the 2-5 min rest?

    Or does supplementation just make sure that if your not getting enough from your diet, that your CP stores will always be maxed out at 15?

    If supplementation gives you more than the normal 15 seconds, does it give you more than 15 seconds just the first time you use it (eg: set one of bench press) or after a 2-5 min rest when you "reset" your stores, do you still get more than 15 seconds?

    Thanks.

    Edit: maybe you can reply in here.
    https://forum.bodybuilding.com/showt...post1603454341
    Last edited by kingofturtles; 04-25-2020 at 06:39 PM.
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  3. #423
    Registered User BurnabyRenos's Avatar
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    Creatine baby!! Its 2020, should be no debate on this.
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  4. #424
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    Various brands use Creapure. Barring some kind of mixed formula, does that mean that each of these brands is selling the exact same creatine, and the only difference is in labeling/cost?
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  5. #425
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    Thank you for this and the other stickies on this information, taking it all in before asking dumb questions! Well written and informative!
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  6. #426
    INDUSTRY INSIDER WillBrink's Avatar
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    Originally Posted by BoreDefer View Post
    Various brands use Creapure. Barring some kind of mixed formula, does that mean that each of these brands is selling the exact same creatine, and the only difference is in labeling/cost?
    If it says Creapure as the source, then yes, they're all selling the same creatine produced in Germany. If not, then various Chinese manufacturers ranging from good to not so good...
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  7. #427
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    Hello,

    I have been taking creatine(creapure) for almost 6 months now. 3 grams a day without a loading period.
    Is it safe for me to keep taking it? Should i go without it for a while?



    Thank you
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  8. #428
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    Originally Posted by Cristian000 View Post
    Hello,

    I have been taking creatine(creapure) for almost 6 months now. 3 grams a day without a loading period.
    Is it safe for me to keep taking it? Should i go without it for a while?



    Thank you
    Your answer is at the start of this very thread.
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  9. #429
    INDUSTRY INSIDER WillBrink's Avatar
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    Originally Posted by Cristian000 View Post
    Hello,

    I have been taking creatine(creapure) for almost 6 months now. 3 grams a day without a loading period.
    Is it safe for me to keep taking it? Should i go without it for a while?



    Thank you
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  10. #430
    INDUSTRY INSIDER WillBrink's Avatar
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    Bit of a "no duh" review and finding at this point, but amazing as it is, there's still people - some educated enough to know better - that claim creatine is dangerous in 2020. This review looks specifically at women:

    Risk of Adverse Outcomes in Females Taking Oral Creatine Monohydrate: A Systematic Review and Meta-Analysis

    Abstract

    Creatine Monohydrate (CrM) is a dietary supplement routinely used as an ergogenic aid for sport and training, and as a potential therapeutic aid to augment different disease processes. Despite its increased use in recent years, studies reporting potential adverse outcomes of CrM have been mostly derived from male or mixed sex populations.

    A systematic search was conducted, which included female participants on CrM, where adverse outcomes were reported, with meta-analysis performed where appropriate. Six hundred and fifty-six studies were identified where creatine supplementation was the primary intervention; fifty-eight were female only studies (9%). Twenty-nine studies monitored for adverse outcomes, with 951 participants. There were no deaths or serious adverse outcomes reported. There were no significant differences in total adverse events, (risk ratio (RR) 1.24 (95% CI 0.51, 2.98)), gastrointestinal events, (RR 1.09 (95% CI 0.53, 2.24)), or weight gain, (mean difference (MD) 1.24 kg pre-intervention, (95% CI −0.34, 2.82)) to 1.37 kg post-intervention (95% CI −0.50, 3.23)), in CrM supplemented females, when stratified by dosing regimen and subject to meta-analysis.

    No statistically significant difference was reported in measures of renal or hepatic function.

    In conclusion, mortality and serious adverse events are not associated with CrM supplementation in females. Nor does the use of creatine supplementation increase the risk of total adverse outcomes, weight gain or renal and hepatic complications in females. However, all future studies of creatine supplementation in females should consider surveillance and comprehensive reporting of adverse outcomes to better inform participants and health professionals involved in future trials.


    https://www.mdpi.com/2072-6643/12/6/1780
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