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  1. #31
    Registered User ISurfNudeBrah's Avatar
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    Originally Posted by SasquatchHunter View Post
    What side effects. I can honestly say I have not noticed any. My cholesterol levels are super low now even while on T.
    ~10% users get diarrhea or muscle/joint pain.

    That is by large the most common SE.
    Supplements formulated with integrity > shady labeling/marketing


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  2. #32
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    Originally Posted by ISurfNudeBrah View Post
    ~10% users get diarrhea or muscle/joint pain.

    That is by large the most common SE.
    I've got other "hormones" causing joint pain right now... nom what I'm sayin? Diarrhea not a problem here. I do shart quarterly but been like this my adult life. Nonetheless if those are the side effects and the primary effects are stopping plaque accumulation and avoiding a stroke or heart attack. I'll take the joint pain and poops. 10/10 times.
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  3. #33
    #SelectTheBest kbayne's Avatar
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    Thought they closed this thread yesterday for some reason? Anyways, linked info on previous page isn't all false. Sure, not the best source, but gives an idea about the subject.

    Originally Posted by XCriticalBenchX View Post
    I am not a huge fan of statins for several reasons but working in health care, involved in PI & audits, I can say the large majority of patients with even modest elevations in cholesterol over 35 years of age and I am talking about levels you and I would not even bat an eye to, are on statins prescribed by there PCP. There usage is abused significantly.

    I got hooked on bergamonte from Heart Help and found it to be highly effective with a very significant impact on HDL elevation which statins never did for me. With heart help no longer available, I just buy NOWs version or something similar.

    Mike
    Jarrow Citrus Bergamot is another good option if you ever need. Another is Krill Oil. Data behind both are quite extraordinary.

    And totally agree, statins are abused very much so when they again, should be the last resort. Family history and labs showing very high cholesterol, yeah, maybe statins are in order.

    Also interesting as many professionals and recent data is showing high cholesterol isn't linked to heart disease.


    Originally Posted by SasquatchHunter View Post
    What side effects. I can honestly say I have not noticed any. My cholesterol levels are super low now even while on T.
    I hope not too low? Your body does need cholesterol.

    As for side effects, here you go:

    https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2849981/
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  4. #34
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    Originally Posted by kbayne View Post
    Without even knowing OPs lipid panel, you recommended statins right off the bat.
    thanks for reading. MD says... "diet and exercise" i do both... but clearly, not enough of.

    HDL 36
    LDL 100
    total cholesterol 184
    triglycerides 242

    a1c 5.6

    12 hours fasted. i did 80 minutes of liss before my blood was drawn. i'm not sure if that could've skewed my numbers.

    i am 5"9' at 200. i am a bit chubby. i GUESStimate I am about 20% bodyfat. I am asking about supplments because the md mentioned them.
    Last edited by rNursejitsu; 03-18-2017 at 01:28 AM.
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  5. #35
    #SelectTheBest kbayne's Avatar
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    Originally Posted by rNursejitsu View Post
    thanks for reading. MD says... "diet and exercise" i do both... but clearly, not enough of.

    HDL 36
    LDL 100
    total cholesterol 184
    triglycerides 242

    a1c 5.6

    12 hours fasted. i did 80 minutes of liss before my blood was drawn. i'm not sure if that could've skewed my numbers.

    i am 5"9' at 200. i am a bit chubby. i GUESStimate I am about 20% bodyfat. I am asking about supplments because the md mentioned them.
    Those numbers aren't horrible. If you get your body fat% down, that will help a good bit I would imagine.

    Do this - buy citrus bergamot and krill oil. Use for 4-6 weeks, get re-tested, and come back and post your numbers. I think you'll be quite surprised. Add more healthy fats in your diet (extra virgin olive oil, virgin coconut oil, almonds, etc). Keep doing your cardio.

    Your A1C is more concerning, as you are almost considered pre diabetic (5.7-6.4).
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  6. #36
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    There are some very negative effect potentials from krill oil (it can cause significant insulin resistance) when compared with fish oil (which actually helps in that area). Fish oil > Phospholipid krill for benefits without some potential harmful sides in various studies.


    Also the bioavailability did not outweigh the cost difference between the two


    Fish >>> Krill as a supplement imo


    I did some extensive research into both a few months back and kept coming to the same conclusion that krill was more marketing hype (and if anything had various downsides when compared to fish). Lets see if I can drag up the studies in my down time
    Last edited by powercage; 03-18-2017 at 02:28 PM.
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  7. #37
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    Just fix your diet and diet exercise regularly. Those numbers are not that bad and only a couple are off. Follow up with your doctor afterwards.
    The science behind proper nutrition and supplementation outweigh the gross negligence of supplement marketing.

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  8. #38
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    Originally Posted by kbayne View Post

    Your A1C is more concerning, as you are almost considered pre diabetic (5.7-6.4).
    He definitely should not take krill oil if he is pre-diabetic as it could make that condition worse.

    Fish oil will potentially help in that area.
    Last edited by powercage; 03-18-2017 at 01:35 PM.
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  9. #39
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    Does anyone have that study showing that the benefits of Niacin actually dont cause an improvement in CVD risk?


    Something to the effect that it was a non beneficial raise in HDL
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  10. #40
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    Last edited by OT2000; 03-18-2017 at 01:46 PM.
    The science behind proper nutrition and supplementation outweigh the gross negligence of supplement marketing.

    This is it. Your one chance, make it right.

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  11. #41
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    Originally Posted by OT2000 View Post
    It's in the NE journal of medicine Cage

    http://www.nejm.org/doi/full/10.1056/NEJMoa1300955
    http://www.nejm.org/doi/full/10.1056/NEJMe1406410

    Also found that
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  12. #42
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    I got hooked on bergamonte from Heart Help and found it to be highly effective with a very significant impact on HDL elevation which statins never did for me. With heart help no longer available, I just buy NOWs version or something similar.
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  13. #43
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    Originally Posted by rNursejitsu View Post
    thanks in advance...

    other than fish oil ... and niacin... what else is there?!?
    You can usually find things like plant sterols that can aid in the reduction of cholesterol.
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  14. #44
    #SelectTheBest kbayne's Avatar
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    Originally Posted by powercage View Post
    There are some very negative effect potentials from krill oil (it can cause significant insulin resistance) when compared with fish oil (which actually helps in that area). Fish oil > Phospholipid krill for benefits without some potential harmful sides in various studies.


    Also the bioavailability did not outweigh the cost difference between the two


    Fish >>> Krill as a supplement imo


    I did some extensive research into both a few months back and kept coming to the same conclusion that krill was more marketing hype (and if anything had various downsides when compared to fish). Lets see if I can drag up the studies in my down time
    Originally Posted by powercage View Post
    He definitely should not take krill oil if he is pre-diabetic as it could make that condition worse.

    Fish oil will potentially help in that area.
    In terms of cholesterol, fish oil doesn't stand a chance against krill. Myself, along with plenty of other individuals have the bloods to prove that. Dante Trudel, performed the krill oil study to a t himself. Noted a very significant improvement in HDL, LDL, and triglycerides. Then proceeded to drop krill and up his fish oil intake to 6 grams per day. HDL dropped more so over LDL and triglycerides (both dropped a few points). My fasted glucose also never took a hit and this was at 2 grams per day for a 5 month period.

    Not sure where you are getting krill causes a significant impact on insulin resistance? I've seen the study with a combination of krill and salmon oil, but no where else shows any significant impact.

    Lastly, as for cost, not much of a difference. People need to realize, if using krill, you're not trying to reach the 2-3 grams of EPA/DHA per day, because if that was the case, then yes, cost would come into play.
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    So
    bergamot
    policosanol
    niacin
    krill / omegas
    Red Yeast Rice

    Good combo?
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    Originally Posted by andrewwww View Post
    So
    bergamot
    policosanol
    niacin
    krill / omegas
    Red Yeast Rice

    Good combo?
    Bergamot and Krill is plenty.

    Pantethine would be another option if you felt the need to add.
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  17. #47
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    Originally Posted by thackes1 View Post
    I'm aware of the side-effects.

    The "side-effect" of living with high cholesterol is death. Cholesterol levels are largely influenced by genetics. So if you have high cholesterol as someone who is eating healthy and exercising and have a healthy body composition, you NEED pharmaceutical intervention if you want to extend your life and not die from cardiovascular disease (the number one killer in US). If someone is experiencing terrible side-effects from statins (it varies from person to person again because of genetics) then alternative pharmaceutical treatments like Anti-PCSK9 treatments (evolocumab) can be used, which are without those side-effect but far more expensive.
    Since you had mentioned evolocumab, this study was posted this week and had very good results (59% LDL decrease with statin + evolocumab vs. placebo).

    Link:
    http://www.nejm.org/doi/full/10.1056...featured_home&

    "The results of a new study show that, when added to statin therapy, evolocumab reduced LDL cholesterol levels by 59% from baseline levels compared with placebo. Adding evolocumab to statin therapy also significantly reduced the likelihood of cardiovascular events. There was a 15% reduction in the risk of the primary composite endpoint of cardiovascular death, myocardial infarction, stroke, hospitalization for unstable angina, or coronary revascularization; and a 20% decrease in the risk of the key secondary endpoint of cardiovascular, myocardial infarction, or stroke. The randomized, double-blind, placebo-controlled study included more than 27,000 patients with atherosclerotic cardiovascular disease and LDL cholesterol levels of 70 mg per deciliter or higher who were receiving statin therapy. Patients were randomized to receive evolocumab (either 140 mg every 2 weeks or 420 mg monthly) or matching placebo as subcutaneous injections. Over a median of 2.2 years of followup, injection site reactions were the only adverse events that were nominally significantly more common with evolocumab; however, those were rare, at a rate of 2.1% compared with 1.6% in the placebo group. The study results, note the researchers, "show that patients with atherosclerotic cardiovascular disease benefit from the lowering of LDL cholesterol levels below current targets." The research, funded by Amgen, was presented Friday at the annual meeting of the American College of Cardiology in Washington, DC"
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  18. #48
    Registered User ISurfNudeBrah's Avatar
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    Originally Posted by andrewwww View Post
    So
    bergamot
    policosanol
    niacin
    krill / omegas
    Red Yeast Rice

    Good combo?
    Red yeast rice is lovastatin, but in an unknown amount (obviously, it's a supplement.. not verified by 3rd party or FDA). It may just have dust and wheat grass in it, only god knows. Speak with your physician about what your options are in regards to lowering cholesterol... some people are genetically predisposed and cannot reduce their numbers to goal or lower just by diet/exercise.

    https://www.consumeraffairs.com/news...es-020315.html
    http://drugtopics.modernmedicine.com...ents?page=full
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  19. #49
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    Let me just point this out quickly, food for though, folks know that red rice yeast acts as a statin correct?
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    Havnt Read much into it but how come lots of folks mention sytrinol?
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  21. #51
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    Originally Posted by ISurfNudeBrah View Post
    Since you had mentioned evolocumab, this study was posted this week and had very good results (59% LDL decrease with statin + evolocumab vs. placebo).

    Link:
    http://www.nejm.org/doi/full/10.1056...featured_home&

    "The results of a new study show that, when added to statin therapy, evolocumab reduced LDL cholesterol levels by 59% from baseline levels compared with placebo. Adding evolocumab to statin therapy also significantly reduced the likelihood of cardiovascular events. There was a 15% reduction in the risk of the primary composite endpoint of cardiovascular death, myocardial infarction, stroke, hospitalization for unstable angina, or coronary revascularization; and a 20% decrease in the risk of the key secondary endpoint of cardiovascular, myocardial infarction, or stroke. The randomized, double-blind, placebo-controlled study included more than 27,000 patients with atherosclerotic cardiovascular disease and LDL cholesterol levels of 70 mg per deciliter or higher who were receiving statin therapy. Patients were randomized to receive evolocumab (either 140 mg every 2 weeks or 420 mg monthly) or matching placebo as subcutaneous injections. Over a median of 2.2 years of followup, injection site reactions were the only adverse events that were nominally significantly more common with evolocumab; however, those were rare, at a rate of 2.1% compared with 1.6% in the placebo group. The study results, note the researchers, "show that patients with atherosclerotic cardiovascular disease benefit from the lowering of LDL cholesterol levels below current targets." The research, funded by Amgen, was presented Friday at the annual meeting of the American College of Cardiology in Washington, DC"
    Nice I hadn't read about statins and evolocumab being used in combination, but the results look good.
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  22. #52
    2011 NPC Eastern USA's XCriticalBenchX's Avatar
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    Originally Posted by kbayne View Post
    Thought they closed this thread yesterday for some reason? Anyways, linked info on previous page isn't all false. Sure, not the best source, but gives an idea about the subject.



    Jarrow Citrus Bergamot is another good option if you ever need. Another is Krill Oil. Data behind both are quite extraordinary.

    And totally agree, statins are abused very much so when they again, should be the last resort. Family history and labs showing very high cholesterol, yeah, maybe statins are in order.

    Also interesting as many professionals and recent data is showing high cholesterol isn't linked to heart disease.




    I hope not too low? Your body does need cholesterol.

    As for side effects, here you go:

    https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2849981/
    The long term side effects are more of a concern than short term which people tend to focus on with statins. The short term effects are rather limited for most, it is the prolonged use that pose a chronic danger down the line that people tend to forget about when they pop there pill daily for years at dinner time.

    I'll have to look into jarrows. Another really really really good cholesterol reducing medication/supplement would be Tudca/Udca. They can do WONDERS. Adequate fiber and psyllium husk also.

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