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  1. #1
    Registered User MHPStrongRep's Avatar
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    MHP MYO-X Myostatin Inhibitor

    If you guys have any questions about our product MYO-X please free to post them. If you have tried the MHP Myo-X we would love to hear your results! The product is still relatively new, but once you guys have tried it we are sure you will love it! The beautiful part is that it works in a completely different manner than anything else so you can use this in conjunctiohn with your other favorite products!
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  2. #2
    das it mane Ronceiro's Avatar
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    Originally Posted by MHPStrongRep View Post
    If you guys have any questions about our product MYO-X please free to post them. If you have tried the MHP Myo-X we would love to hear your results! The product is still relatively new, but once you guys have tried it we are sure you will love it! The beautiful part is that it works in a completely different manner than anything else so you can use this in conjunctiohn with your other favorite products!
    LMAO if this is srs. But I'll bite 1st


    Explain how your product inhibits myostatin, with reference to the key molecules in this supp, how they are absorbed and distributed through the body, how the body processes them (e.g. liver/kidney metabolism) the key molecular targets (i.e. specifically naming metabolites or cell receptors) for the supplement and whether the supp inhibits:

    1)myostatin synthesis or
    2) target cell receptor binding to myostatin

    If 2...is it a competitive or non-competitive antagonist?
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  3. #3
    Cell Technician Diesel0022's Avatar
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    on recharge^^
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  4. #4
    LETS GET WEIRD Shermanatorx's Avatar
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    I just emailed this thread to Dr. McPherron and Dr. Lee...


    this should go well.
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  5. #5
    Version 2.0 DanND33's Avatar
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    ...till we meet again
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  6. #6
    ISOFLEX'D xStevenx's Avatar
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  7. #7
    Registered User Ricky5295's Avatar
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    Its not cheap either! cmon man
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  8. #8
    Registered User MHPStrongRep's Avatar
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    In an effort to identify whether MYO-T12, the active ingredient in MYO-X is actually absorbed orally and pharmaco-kinetically active in the human model, a human study was undertaken. Testing utilized standards for verification with confirmations run by ELISA and quantitations by Liquid Chromatography Tandem Mass Spectrometer using third degree fragmentation. Results showed a predicted zero level of follistatin at baseline with a myostatin level of 46pg/ml. 12 hours after Folstaxan™ dosing, serum follistatin measured 57.1pg/ml with a decline of myostatin to 34pg/ml. 24 hours after the initial dosing, follistatin levels began to predictably drop from the time of initial dosing to 11.4pg/ml. Yet myostatin continued to decline slightly with a 24 hour level of 31pg/ml. These results clearly indicated that MYO-T12, when orally ingested, resulted in detectable serum follistatin. Furthermore, this resultant follistatin presence has significant pharmaco-kinetic activity as shown by the hormonal down-regulation of serum myostatin (Colker C, Absorption profile and hormonal influences of fertile egg yolk ingestion in the human. Journal of the American College of Nutrition, Volume 25, No.5, page 458, Abstract 66; October 2006). Beyond that, precise molecular pharmocokinetic studies at the cellular level on MYO-X have not been performed. But based on the available research on the biologically active sub-fractions, our scientists reason that the action is not based on competitive or non-competitive inhibition at the level of the receptor. Rather the more likely theory is down-regulation of myostatin production intra-cellularly at the level of the DNA.
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  9. #9
    Registered User MHPStrongRep's Avatar
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    I'm pretty sure I'll get the "science buffs" in here trying to refute the above, but all I can say is try it. It's like the analogy of driving...I can describe in every detail how to drive, but it's a completely different experience being behind the wheel and actually driving.
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  10. #10
    Banned Bacteroides's Avatar
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    I has theories. I has logs. I has sheeple. I has no relevant end-point data.

    SHOW ME THE FOCKING RELEVANT DATA!
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  11. #11
    Registered User MHPStrongRep's Avatar
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    mhpstrong(DOT)com/the-myo-x-breakthrough-inside-story

    Click on the link above and it should be all the information you are looking for! Thanks for your interest!

    EDIT:
    I tried posting the link but I do not have enough posts so please visit the MHP website and click on the Myo-X tab to learn more....plenty of studies are posted on that link!
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  12. #12
    Cell Technician Diesel0022's Avatar
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    Kinda like oral Hgh products (l-dopa, etc etc), this would just be the oral peptide

    For the "real" myostatin inhibitors, the delivery is through a viral vector as it is a gene. This isn't about amplifying what you already have; this is about adding genetic material to what you already have. Do yourself a favor and read up on viral vectors and modifying your DNA.

    Follistatin has some nasty sides. For one, myostatin inhibition causes a chain of events including the reduction of factors (tgf-beta) that contribute to fibrosis and cartilage /tendon repair. Won't even get started on the immunodeficiency disorders that are induced.
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  13. #13
    Registered User crg68's Avatar
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    so you take it once a day only ?When is the best time to take it?
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  14. #14
    Registered User crg68's Avatar
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    bump
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  15. #15
    Registered User MHPStrongRep's Avatar
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    You only need to take it once a day, and as long as you are consistent you are fine with timing. But for optimal results we suggest taking approximately 12-16hrs before you workout....so if you workout at 7P at night, then just take it at 7A around the time you would wake up.
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  16. #16
    Registered User F3D's Avatar
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    Bump for more input.
    Latest Review:

    http://forum.bodybuilding.com/showthread.php?t=130648573
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  17. #17
    Cell Technician Diesel0022's Avatar
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    Originally Posted by MHPStrongRep View Post
    You only need to take it once a day, and as long as you are consistent you are fine with timing. But for optimal results we suggest taking approximately 12-16hrs before you workout....so if you workout at 7P at night, then just take it at 7A around the time you would wake up.
    Is Folstaxan the same as Follistatin
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  18. #18
    Registered User KBoss302's Avatar
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    Is there any direct proof that MYO-X helps build more muscle and strength? Any double-blind, placebo controlled studies using trained athletes who, after N weeks of use, gained significantly more lean mass and strength than the placebo group?

    If not, then I don't see MYO-X as being any different than the first myostatin scam pulled by Ultimate Nutrition, Biotest, Cytodyne Technologies, and Pinnacle back in 2001. Seeing a reduction in serum myostatin levels is all fine and dandy. But that doesn't necessarily translate into more muscle growth like the advertisements suggest.
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  19. #19
    Registered User metallic1's Avatar
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    Originally Posted by MHPStrongRep View Post
    You only need to take it once a day, and as long as you are consistent you are fine with timing. But for optimal results we suggest taking approximately 12-16hrs before you workout....so if you workout at 7P at night, then just take it at 7A around the time you would wake up.
    is it best taken on an empty stomach, or after a meal? if on empty, how long after a meal is best? how long before or after is it best to take a pre-workout?, is it ok to take other products with myo-x?, test boosters, estrogen blockers, products like erase... i dont think anyone has asked these questions yet., im curious, and would like to try a few bottles.
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  20. #20
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    Originally Posted by MHPStrongRep View Post
    I'm pretty sure I'll get the "science buffs" in here trying to refute the above, but all I can say is try it. It's like the analogy of driving...I can describe in every detail how to drive, but it's a completely different experience being behind the wheel and actually driving.
    When you're selling a new supplement that costs over seventy bucks for a month supply, "just try it!" doesn't quite cut it...
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  21. #21
    Registered User KBoss302's Avatar
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    I think the OP got scerred away.
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  22. #22
    Registered User memoware's Avatar
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    I concurr

    Originally Posted by metallic1 View Post
    is it best taken on an empty stomach, or after a meal? if on empty, how long after a meal is best? how long before or after is it best to take a pre-workout?, is it ok to take other products with myo-x?, test boosters, estrogen blockers, products like erase... i dont think anyone has asked these questions yet., im curious, and would like to try a few bottles.
    I received my first Myo-x yesterday I Planned on start taking it next week.
    Rep guy, please answer metallic1's questions, after reading them I will start until I know that. This info is not available in the label or the fancy box...thanks
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  23. #23
    Registered User MHPStrongRep's Avatar
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    Originally Posted by metallic1 View Post
    is it best taken on an empty stomach, or after a meal? if on empty, how long after a meal is best? how long before or after is it best to take a pre-workout?, is it ok to take other products with myo-x?, test boosters, estrogen blockers, products like erase... i dont think anyone has asked these questions yet., im curious, and would like to try a few bottles.
    We suggest taking first thing in the morning, before breakfast. This times you up pretty well with an afternoon workout, it is important to stay consistent with the time that you take MYO-X. You can compliment MYO-X with other supplements, it works differently from a protein, test booster, and other products, so it can be combined with any other items in your stack. We actually suggest something like T-Bomb II, becuase this will optimize your muscle building, test boosters compliment MYO-X very well.

    As far as the pre-workout, this can be taken anytime. We would suggest, that if you take a pre-workout after MYO-X, that you wait about 45 minutes to an hour. Eating food or drinking a shake can sometimes affect the feeling you get from a pre-workout. Please keep in mind that for optimal results we suggest taking MYO-X Approximately 12-16 hours before your workout.
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  24. #24
    Cell Technician Diesel0022's Avatar
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    Originally Posted by Diesel0022 View Post
    Is Folstaxan the same as Follistatin
    *cough*
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  25. #25
    Registered User MHPStrongRep's Avatar
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    Originally Posted by KBoss302 View Post
    Is there any direct proof that MYO-X helps build more muscle and strength? Any double-blind, placebo controlled studies using trained athletes who, after N weeks of use, gained significantly more lean mass and strength than the placebo group?

    If not, then I don't see MYO-X as being any different than the first myostatin scam pulled by Ultimate Nutrition, Biotest, Cytodyne Technologies, and Pinnacle back in 2001. Seeing a reduction in serum myostatin levels is all fine and dandy. But that doesn't necessarily translate into more muscle growth like the advertisements suggest.
    Past myostatin inhibitors marketed as dietary supplements simply didn’t end up working. The problem was that the only data to support their efficacy at inhibiting myostatin was that in a test tube or loosely based on somewhat unrelated animal studies. The main ingredient was a brown sea algae called cystoseira canariensis. The resident expert on the subject of cystoseira canariensis as a purported myostatin inhibitor is a D.S. Willoughby from the Department of Human Performance at Baylor University in Texas. Willoughby reported that cystoseira canariensis in two studies formulas containing cystoseira canariensis had no effect on muscle mass and strength. In addition, these products had no effect on serum myostatin levels. Claims made on this ingredient are based in-large on a single vitro (test tube only) study. Moreover, products that contained it never caught on with consumers because they simply didn’t work.

    Furthering the point, the main human study on the product was a miserable failure. It was a 12 week study (double blind) on 22 males who were randomly assigned to one of 2 groups, being placebo of Cystoseira canariensis (specifically 1200mg/day). Both groups underwent rigourous weightlifting training yet showed no difference in outcome between the treatment and the placebo groups. Worse yet, myostatin levels were not even measured. In sharp contrast, MYO-X has been demonstrated to have a clearly understood mechanism of action in the human model and was shown in clinical research to reduce serum myostatin levels in healthy human study subjects.
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    Originally Posted by TheWiseEggroll View Post
    When you're selling a new supplement that costs over seventy bucks for a month supply, "just try it!" doesn't quite cut it...
    Will "check the logs, bro!" work beter??????
    I've been wronged by that super dirty son of a bitch dazed" crew.
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    Originally Posted by Diesel0022 View Post
    Is Folstaxan the same as Follistatin
    Originally Posted by Diesel0022 View Post
    *cough*
    I think the OP is asking higher ups than copy and pasting.

    No answer?
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    Originally Posted by Diesel0022 View Post
    Is Folstaxan the same as Follistatin
    I apologize for the delay Diesel0022. I wanted to get all the facts straight with Dr. Colker before posting about Folstaxan. I hope that this addresses your question correctly.

    Celldyne Biopharma was hired by Dr. Colker to develop Folistaxan, a first generation myostatin inhibitor he invented and patented. The first research using Folistaxan was done in 2006. Though two out of the seven subjects tested were non-responders, the mean change overall in myostatin among the subjects was a myostain reduction by -11.32% in 24 hours.

    MYO-T12 (the active ingredient in MYO-X) is much more advanced, concentrated and potent next generation supplement. The new MYO-T12 sample Colker created was 3rd party tested and found to have a potency 6.45 times Celldyne’s version of Folstaxan™.

    Colker's latest generation of this product was tested in 10 healthy adult male human subjects while only administering only a single 10 gram serving size (half the amount needed by subjects in the last study for Folistaxan) Use of MYO-T12 caused a staggering 46% drop in myostatin from baseline across all ten subjects, for 100% response rate.

    Colker partnered with MHP to increase purity and production capacity for manufacture of MYO-X, so that he could finally bring the only clinically research myostatin inhibitor to the masses.
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    Not even close, it's a simple yes or no, is Folstaxan the same as Follistatin
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    Originally Posted by Diesel0022 View Post
    Not even close, it's a simple yes or no, is Folstaxan the same as Follistatin
    Absolutely not
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