Shadar's Informative Links - Share yours as well! *Updated 03-13-11*

[Synapsin]

http://forum.bodybuilding.com/showpo...03&postcount=5

Not to toot my own horn or anything but I figure it'll be asked multiple times

[Mr.Cooper69]

http://forum.bodybuilding.com/showpo...03&postcount=5

Not to toot my own horn or anything but I figure it'll be asked multiple times

its been removed?

[Synapsin]

"Indeed. Agmatine is said to serve as an endogenous neuroprotective neuromodulator which is co-released during neurotransmitter release. Agmatine is a specific competitive antagonist of the NMDA receptor and it's guanidine moiety makes it different than traditional NMDA receptor antagonists. The important thing to distinguish here is that exogenous application of Agmatine and D-Aspartic acid work on different mechanisms for the NMDA receptor, so regardless of one being an antagonist and the other an agonist, they do not overlap. Exogenous D-aspartic acid application utilizes the R-type VGCCs and none of the others, while exogenous Agmatine is said to use the L-type VGCCs and shows no signs of inhibition of the R-type VGCCs.

Another important thing to note is that Agmatine was found as an effective preventative method when it comes to glutamatergic NMDA apoptosis. "

http://forum.bodybuilding.com/showpo...33&postcount=5

its been removed?

Working now

[shadar]

"Indeed. Agmatine is said to serve as an endogenous neuroprotective neuromodulator which is co-released during neurotransmitter release. Agmatine is a specific competitive antagonist of the NMDA receptor and it's guanidine moiety makes it different than traditional NMDA receptor antagonists. The important thing to distinguish here is that exogenous application of Agmatine and D-Aspartic acid work on different mechanisms for the NMDA receptor, so regardless of one being an antagonist and the other an agonist, they do not overlap. Exogenous D-aspartic acid application utilizes the R-type VGCCs and none of the others, while exogenous Agmatine is said to use the L-type VGCCs and shows no signs of inhibition of the R-type VGCCs.

Another important thing to note is that Agmatine was found as an effective preventative method when it comes to glutamatergic NMDA apoptosis. "

http://forum.bodybuilding.com/showpo...33&postcount=5



Working now

I've added the link to my personal list, it will make the next update.

Would a good tag next to it be "Works well with DAA" ?

[Valenzuelatech]

Thread has been updated

thanks to all who contributed so far

"Indeed. Agmatine is said to serve as an endogenous neuroprotective neuromodulator which is co-released during neurotransmitter release. Agmatine is a specific competitive antagonist of the NMDA receptor and it's guanidine moiety makes it different than traditional NMDA receptor antagonists. The important thing to distinguish here is that exogenous application of Agmatine and D-Aspartic acid work on different mechanisms for the NMDA receptor, so regardless of one being an antagonist and the other an agonist, they do not overlap. Exogenous D-aspartic acid application utilizes the R-type VGCCs and none of the others, while exogenous Agmatine is said to use the L-type VGCCs and shows no signs of inhibition of the R-type VGCCs.

Another important thing to note is that Agmatine was found as an effective preventative method when it comes to glutamatergic NMDA apoptosis. "

http://forum.bodybuilding.com/showpo...33&postcount=5

I've been hearing allot about Agmatine, mostly users reporting a powerful pump. is this due to NO release? Also, can high doses of Agmatine produce a stimulant-like effect due to it's activity on catecholamine release?

[Synapsin]

I've added the link to my personal list, it will make the next update.

Would a good tag next to it be "Works well with DAA" ?

Sure, I would have said something like "Would Agmatine work with DAA or vice versa".

Thread has been updated

thanks to all who contributed so far



I've been hearing allot about Agmatine, mostly users reporting a powerful pump. is this due to NO release? Also, can high doses of Agmatine produce a stimulant-like effect due to it's activity on catecholamine release?

http://forum.bodybuilding.com/showpo...1&postcount=17

As for a stimulant like effect, I imagine at some point it *could* but I doubt it unless you're using a dose I would not recommend. A good read for this would be http://www.leanbulk.com/forum/articl...lide-show.html (not sure if this breaks any rules to link this but it has a good summary of Agmatine there).

[EntropyIncrease]

Would a good tag next to it be "Works well with DAA" ?

If you make a section for that be sure to add some of andy's and matt's comments about ldopa . . . if its not already in here somewhere.

[em-dubya]

If you make a section for that be sure to add some of andy's and matt's comments about ldopa . . . if its not already in here somewhere.

Then again its probably only relevant to 10% of users(totally fictitious amount)...however IF you feel you need L-dopa then the new PCT Assist will be out in about 2 weeks

[Striver]

To add to the list:

Layne Norton research and conclusions on ALA dosing and timing http://www.bodybuilding.com/fun/layne25.htm

[Valenzuelatech]

As for a stimulant like effect, I imagine at some point it *could* but I doubt it unless you're using a dose I would not recommend. A good read for this would be http://www.leanbulk.com/forum/articl...lide-show.html (not sure if this breaks any rules to link this but it has a good summary of Agmatine there).

Those threads are way over my head at this point. I need to do some reading up on pathways to get a general understanding. What's a good place to start?

To add to the list:

Layne Norton research and conclusions on ALA dosing and timing http://www.bodybuilding.com/fun/layne25.htm

I read this back in 2008 and it was enough to convince me to start supplementing with ALA. Because ALA may prevent other antioxidants from becoming pro-oxidants during exercise due to oxidative stress, I dose it concomitant with my other antioxidants: Idebenone, Circumin, NAC & Vitamin C.

I am a little skeptical of its pro ported ability to control blood glucose levels in healthy people. Has there been any recent data that suggests this? For experimentation purposes: I've tried ALA on an empty stomach 15-30 minutes before a meal with dosages ranging from 300mg to 1800mg and never felt hypoglycemic which I was expecting

[shadar]

If you make a section for that be sure to add some of andy's and matt's comments about ldopa . . . if its not already in here somewhere.

I suppose some general info on DAA would be a good place to start, along with good combination products. Since it's the new "it" supplement every company uses.

Thread has been updated

thanks to all who contributed so far

Thanks again!

To add to the list:

Layne Norton research and conclusions on ALA dosing and timing http://www.bodybuilding.com/fun/layne25.htm

Thanks for the contribution!

[chasinSKURT]

Nice compilation.

Though I would agree that when used for increasing testosterone concentrations, ZMA will not solicit any efficacious effect, I still like it as a supplement for overall health. Especially for active gym-goers.

[chasinSKURT]

"Indeed. Agmatine is said to serve as an endogenous neuroprotective neuromodulator which is co-released during neurotransmitter release. Agmatine is a specific competitive antagonist of the NMDA receptor and it's guanidine moiety makes it different than traditional NMDA receptor antagonists. The important thing to distinguish here is that exogenous application of Agmatine and D-Aspartic acid work on different mechanisms for the NMDA receptor, so regardless of one being an antagonist and the other an agonist, they do not overlap. Exogenous D-aspartic acid application utilizes the R-type VGCCs and none of the others, while exogenous Agmatine is said to use the L-type VGCCs and shows no signs of inhibition of the R-type VGCCs.

Another important thing to note is that Agmatine was found as an effective preventative method when it comes to glutamatergic NMDA apoptosis. "

http://forum.bodybuilding.com/showpo...33&postcount=5



Working now

Awesome posts.

Agmatine, for coming up on 4 years now (hopped on the MAN bandwagon with BluePrint when it was initially released), has been my favorite supplement.

[shadar]

Nice compilation.

Though I would agree that when used for increasing testosterone concentrations, ZMA will not solicit any efficacious effect, I still like it as a supplement for overall health. Especially for active gym-goers.

I'm definitely willing to post up some competing info for people to read and decide on themselves. I'm not too fond of ZMA products personally since they are just overpriced zinc + mag + b6 combinations. But all three of those definitely have their own unique health benefits, particularly if people are deficient in any of them. A decent multi should satisfy this need though.

If you'd like to write up a little piece on why ZMA is beneficial that post could be linked. I've really not found too many great ZMA threads or posts so far as most just involve anecdotal accounts of some people sleeping better and others not noticing a difference. Very few posts explaining the unique benefits of each aspect of ZMA, etc.

I've just been swamped the past few days, can't even get out a review I owe Synapsin. Hopefully tonight or tomorrow.

[PuZo]

Contemporary Issues in Protein Requirements and Consumption for Resistance Trained Athletes

http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2129150/

International Society of Sports Nutrition position stand: creatine supplementation and exercise

http://www.jissn.com/content/4/1/6

[cjwav34]

Pinch The Bear on the Carnitines:
http://broscience.com/andrew-abbate-...arnitines.html

Layne on protein digestion:
http://broscience.com/layne-norton-p...digestion.html

Meal Frequency:
http://www.jissn.com/content/pdf/1550-2783-8-4.pdf

[snagency]

Meal Frequency:
http://www.jissn.com/content/pdf/1550-2783-8-4.pdf

^^ love the cliffs on that one..

1. Increasing meal frequency does not appear to favorably change body composition in
sedentary populations.
2. If protein levels are adequate, increasing meal frequency during periods of
hypoenergetic dieting may preserve lean body mass in athletic populations.
3. Increased meal frequency appears to have a positive effect on various blood markers of
health, particularly LDL cholesterol, total cholesterol, and insulin.
4. Increased meal frequency does not appear to significantly enhance diet induced
thermogenesis, total energy expenditure or resting metabolic rate.
5. Increasing meal frequency appears to help decrease hunger and improve appetite
control.

[mikeonopiates]

this thread died out quicker than charlie sheen's brain.

[Mr.Cooper69]

this thread died out quicker than charlie sheen's brain.

LOL Then keep it going. You post a scientific question you have about supplements, someone here will answer it.

[mikeonopiates]

LOL Then keep it going. You post a scientific question you have about supplements, someone here will answer it.

haha yeah that is true, overall this thread is very useful, but we need more articles and such posted. not many ppl have been posting in here lately, ill try to find some of my favorite articles and post em soon.

[Supplement-Slut]

Location: Daytona Beach

Yo Benny how far you from Gainsville? I'm headed back next week so let's arrange a Bro-date @Chiptole.

You're coming with me

[jquintinjr]

Location: Daytona Beach

Yo Benny how far you from Gainsville? I'm headed back next week so let's arrange a Bro-date @Chiptole.

You're coming with me

bro date at chipotle in framingham bro?

[shadar]

Location: Daytona Beach

Yo Benny how far you from Gainsville? I'm headed back next week so let's arrange a Bro-date @Chiptole.

You're coming with me

Gainesville is a PITA to get to from Daytona, no good roads connecting the two. It's a couple of hours. Depending when you're heading in though I could try to meet up with ya. I've been completely slammed the past few weeks, thus my absence around here lately. So no guarantees.

Have just enough time to get in my workouts and respond to some PM's and such occasionally.

I did run into a forum poster today at the gym. Don't think he's a supp forum poster too much, more the workout and other forums I believe.

I'll hopefully get around to adding the links people posted and digging up a few more of my own to make another update in the not too distant future.

[Supplement-Slut]

bro date at chipotle in framingham bro?

South Shore > North Shore

Gainesville is a PITA to get to from Daytona, no good roads connecting the two. It's a couple of hours. Depending when you're heading in though I could try to meet up with ya. I've been completely slammed the past few weeks, thus my absence around here lately. So no guarantees.

I've PM'ed you my cell #. You familiar with PR Blvd, Gainsville? See ya there.

-Three Faces of Fear(tm)

[or_yourlivingtodie]

if anyone has any good threads about 3,3/3,5 and thyroid suppression please post them up........

ive seen this brought up quite a few times in the past week

[itzDodge]

if anyone has any good threads about 3,3/3,5 and thyroid suppression please post them up........

ive seen this brought up quite a few times in the past week

I actually asked Pinch to do these on another forum but he's not a proponent of them so that's about all the info you need right there.

[j2smile]

[QUOTE=Synapsin;645094863]Sure, I would have said something like "Would Agmatine work with DAA or vice versa".

Im on SNS DAA caps+Inhibit e cant wait to see my samples of Agmatine that MR Cooper69 sending me.

[PuZo]

How about which vitamins compete for absorption like calcium vs zinc etc?

[eldawg]

How about which vitamins compete for absorption like calcium vs zinc etc?

You may find some of that info on minerals here - http://forum.bodybuilding.com/showpo...&postcount=299

The rest of that thread is also very good.

[cjwav34]

How about which vitamins compete for absorption like calcium vs zinc etc?

Honestly it's nothing to worry about.