I was reading about GABA to get to know the product better, but I couldn't really make a conclusion if GABA can damage your memory and learn ability. A site said GABA can interfere with memory, but on the forum people stack GABA in cognitive stacks. -->???
Can it damage your brain? Is it bad for your learn ability? Are there many dangers?
(or can it be good for your memory and cognitive function)
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Thread: GABA and memory
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10-13-2010, 03:23 PM #1
GABA and memory
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10-13-2010, 03:40 PM #2
Really, I found 6 sites that said it can be bad, 6 sites that said it can improve.. This is confusing
Any person who really knows this sure, or can explain it clearly?
Are there products who can improve HGH AND memory/(brain activity/concentration)? That there's no doub about the effectLast edited by dieter_dh; 10-13-2010 at 03:47 PM.
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10-13-2010, 03:47 PM #3
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10-13-2010, 03:48 PM #4
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10-13-2010, 03:49 PM #5
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10-13-2010, 03:54 PM #6
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10-13-2010, 03:54 PM #7
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10-13-2010, 03:57 PM #8
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10-13-2010, 04:08 PM #9
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10-13-2010, 04:10 PM #10
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10-13-2010, 04:16 PM #11
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10-13-2010, 04:29 PM #12
GABA wont do this, since it can cross the blood-brain barrier. I saw those studies too, about gaba-B agonists i believe... if you're worried don't take phenibut or picamilon, both of which cross the bbb.
Now, I don't see how that stuff could cause PERMANENT memory issues... it'd just be short like the benzos, alcohol, etc?Disclaimer: The above statments represent my own opinion. The above statements do not constitute medical advice.
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10-13-2010, 04:39 PM #13
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10-13-2010, 04:47 PM #14
I've run plenty of GABA, Phenibut and a bit of Picamolin. None of which had any detrimental effect on memory. Short term, too much Phenibut will f anybody up - but no, no studies I'm aware of suggest GABA would cause any damage. In fact, short term GH elevations exceeding fourfold above baseline have been reported. This, with a 3 g dose prior to exercise:
http://www.ergo-log.com/gabagh.html
Whether this translates to more muscle and/or less fat over time is anyone's guess. For the pricepoint though, its a logical first step if interested in elevating GH.
There are better nootropics than GABA for memory. The European states are far ahead of the West in this area. GABA is typically used as a relaxant prior to bed and does impart said relaxation, although an unpleasant flushing effect can be realized for those unfamiliar with it.Last edited by Mixelflick; 10-13-2010 at 05:07 PM.
Author of The Blueprint - Want BIG gains WITHOUT drugs?
Want to get to Gainsville FAST? - Google Synthagen or theblueprintbulletin
My post reflects only my opinion and is in no way considered required practice - in whole or in part. Specific medical advice should be obtained from a licensed health care practitioner PRIOR to beginning ANY new diet, exercise, supplementation or training program.
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10-13-2010, 05:11 PM #15
Are you sure the literature you were reading did not pertain to the pharmacodynamic effects of benzodiazepines on GABAa receptors? Benzodiazepine receptor agonists exert their effects on GABAa receptors - causing an inhibitory effect on neurotransmission, thereby potentiating the GABAergic decrements of neuronal firing rates. This would coincide with what you read reguarding short-term memory loss, ect.
~
Wherever progression lacks.... regress can be found in abundance.
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10-13-2010, 05:26 PM #16
For those of you who are referring to compounds that enhance GH expression, please take note of the information provided in the following post....
growth hormone: Why are we trying to enhance it, and... Is it even working?~
Wherever progression lacks.... regress can be found in abundance.
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10-13-2010, 05:30 PM #17
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10-13-2010, 05:31 PM #18
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10-13-2010, 06:42 PM #19Originally Posted by NO HYPE~
Wherever progression lacks.... regress can be found in abundance.
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10-13-2010, 06:49 PM #20Author of The Blueprint - Want BIG gains WITHOUT drugs?
Want to get to Gainsville FAST? - Google Synthagen or theblueprintbulletin
My post reflects only my opinion and is in no way considered required practice - in whole or in part. Specific medical advice should be obtained from a licensed health care practitioner PRIOR to beginning ANY new diet, exercise, supplementation or training program.
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10-13-2010, 09:49 PM #21
Kinda yeah. The reason GABAa is inhibitory is because of the Cl- channels it has (the association of them). The reversal potential for chloride is usually more negative than the threshold potential. The hyperpolarization of the Cl- chan itself is what causes it to be inhibitory. You wouldn't need benzos to cause an inhibitory effect, all that matters for what determines excitation or inhibition is the receptor type. So for example, GABAb is also inhibitory (mind you it's a Metabotropic receptor), but it's due to K+ channels rather than chloride channels now (or blocking calcium channels). Benzos enhance GABA transmission by binding to the alpha and delta subunits of GABAa receptors. So like I said, they can keep the channels open longer so you're right, it'd potentiate the NT but it doesn't need to happen for an inhibitory effect, it'd just make it last longer.
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10-13-2010, 10:02 PM #22
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10-13-2010, 10:05 PM #23
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01-20-2011, 07:28 PM #24
Sorry to revive an old thread, but I came across this searching for answers as to why GABA is making my short term memory crap.
Let me tell you; it DOES screw with your short term memory (for me anyway). I've been keeping logs for the last 2 years of different supplements that I am experimenting with to help treat my anxiety and I've repeatedly found that as soon as a start GABA, I can't remember sh*t. I've documented this on at least 3 different occasions months apart.
To the original poster: Would you mind posting links of those studies explaining why it does this? I'm having trouble finding anything.
Even though GABA doesn't cross the blood brain barrier, it definately has an effect on me. Within 30 minutes of ingesting it, I feel relaxed and my anxiety improves greatly.
Drugs can be be actively transported by a variety of carriers, or leak through epithelial junctions or through certain osmoregulatory anion channels to the brain. The BBB isn't the only way in.
Edit: Just an addition for those who are interested, on all 3 occassions my memory was back to normal within 2 days of stopping GABA.Last edited by Jarus187; 01-20-2011 at 07:35 PM. Reason: Addition
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05-10-2017, 03:34 PM #25
Memory loss
Hi, I know this is from a long time ago, just wondering if you found out any insights into this topic. I am experiencing short-term / working memory loss while taking a GABA-related muscle relaxant. It seems to go away when I stop taking it, but I'm worried about potential long-term effects.
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05-10-2017, 07:09 PM #26
What is the relaxant you're using? I believe you're speaking of a pharmaceutical drug versus supplemental gaba, correct?
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Disclaimer: The statement above reflects that of my own opinion and in no way that of MAN Sports. Our products are not intended to diagnose, treat, cure, or prevent any disease.
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