AEN-PreSurge Unleashed FAQ, NEXT Generation pre-workout formula!

[ATHLETIC EDGE NUTRITION]

PreSurge® Unleashed

Extreme SURGE of Creatine, Nitric Oxide & Insane RUSH of Energy!

Redefining Pre-Workout supplementation as we know it!

The pre-workout category is one of the oldest most cluttered categories in sports nutrition today. Sadly, if you look closely at the supplement facts panels of many of these products, you will see the same OLD SCHOOL formula that has been around since early 2000. And despite huge evolutions in sports nutrition research, these pre-workout formulas stay the same. We see NO reason to recycle old largely ineffective, outdated formulas, simply to try and make slight improvements, like other companies do.
Staying true to our tradition of bringing out ONLY premium, innovative, uncompromised formulas, we are pleased to introduce PreSurge Unleashed!

PreSurge Unleashed is the NEXT huge leap in pre-workout supplementation, incorporating all the latest advancements in sports nutrition science.

Formulated from the ground up to be completely original and innovative, PreSurge Unleashed will simply perform like no other pre-workout formula in the world.



PreSurge Unleashed Highlights:

• Experience The Strongest Pre-Workout Formula in Sports Nutrition
• Increase Nitric Oxide Synthesis & Vascularity with patented GlycoCarn®
• Maximize Blood flow, Engorging Muscles bringing on Extreme Muscle Fullness & Hardness
• Extreme Strength Gains with German made Creapure®, the world’s purest creatine with a proven safety profile
• Dramatically Increase Creatine uptake with specialized, research supported Russian Tarragon Extract, NO CARBS NEEDED
• Insane, yet Clean & Jitter Free Energy, Intensity & Laser-Like Focus
• Naturally stimulates alpha waves activity in the brain with patented clinically backed Suntheanine® heightening mental acuity, promoting concentration & reducing the jitters and negative side effects of caffeine
• Patented, clinically backed Neuravena® for a “Mind-Muscle” Connection Like You’ve Never Experienced Before
• Specifically Designed to Prime & Sensitize Your Muscles for The Anabolic Flood of Muscle Building Peptides & Amino-Acids brought about from our Intra-Workout IntrAbolic. Phase-2 in our Nutrient timing stack.




Head to head comparison of “old school” pre-workout formulas versus PreSurge Unleashed

Let’s take an insightful look at the core of the current old breed of pre-workout formulas and how PreSurge Unleashed REDEFINES the category as we know it.

Old School pre-workout formula- Generic low grade creatine or inferior forms.

PreSurge Unleashed solution -Creapure® brand creatine monohydrate.

Unlike other pre-workout formula’s, who use the cheapest creatine monohydrate they can get their hands on. We have licensed the German made Creapure; the world’s purest creatine, with a proven safety profile. Creapure brand of creatine monohydrate is produced with a unique patented non-carcinogenic process in a FDA registered GMP plant in Germany with no possible risk of cross contamination or high levels of its breakdown byproduct creatinine that can occur with cheaper creatine’s. Creapure is recognized for consistent and homogenous quality (min 99.9% creatine monohydrate) which increases your value, while keeping it contaminate free. Look for the creapure® logo on the label of PreSurge to ensure you are getting the best creatine in the world. Creapure is the KING of all creatine's.

Old School pre-workout formula- Loaded with carbohydrates to help with creatine uptake. While large amounts of carbohydrates have been shown to increase creatine uptake into the muscle. Many people don’t want consume huge amounts of fat inducing, physique destroying simple sugars, simply to increase creatine absorption.

PreSurge Unleashed solution - Russian Tarragon extract, NO CARBS NEEDED!

PreSurge Unleashed is the world’s first supplement to use a research backed specialized extract of russian tarragon(Artemisia dracunculus L). Let’s take a closer look at what this incredible ingredient can do for you. This EXACT extract was recently shown in a study, combined with creapure creatine(the creatine we use in PreSurge) to drastically increase the uptake of creatine into skeletal muscle. The results were STAGGERING, showing this extract could bring about skeletal muscle absorption comparable to spiking insulin with large amounts of high glycemic carbohydrates and or protein. This specialized, Russian Tarragon extract will make your muscles like creatine sponges! Perfect for individuals looking to maximize muscle fullness and bring about ultra lean and hard looking muscles.
This is a HUGE breakthrough in the science of creatine supplementation and makes the consumption of huge amounts of simple sugars, obsolete.

Old School pre-workout formula- Loaded with Arginine - Most of the old school formulas, are largely formulated using the amino-acid arginine to increase nitric oxide( NO). The problem is, studies have repeatedly shown arginine is not the rate limiting factor for NO synthesis in humans, meaning by taking extra, it does not drive your body to make more NO as a result. Even when large oral doses of arginine were taken at 7-20grams a day were taken, the studies show no increase in NO levels. Simply stated: The research DOES NOT support that taking extra arginine orally will increase NO levels. Additionally, high doses of arginine, can have you running to the bathroom. Certainly not desirable during your workout.

PreSurge Unleashed solution- We take a three angled approach at boosting NO:

1. GlycoCarn(gycine propionyl l-carnitine)
At the core of our nitric oxide/vascularity blend is the patented form of L-carnitine, GlycoCarn™(gycine propionyl l-carnitine), which has CLINICLY been shown to increase NO. GlycoCarn is the FIRST ingredient shown in research to actually increase nitric oxide synthesis in HUMANS when taken orally.

2. Epimedium- (standardized for 40% Icariin)
PreSurge utilizes an extract of icariin from the herb epimedium. Icariin is the constituent of the epimedim that is largely believed to bring about the vascular effects. Icariin has been shown in research to stimulate both short term production of nitric oxide(NO), as well as having longer term effects on endothelia nitric oxide synthase(eNOS), the enzyme needed to synthesize NO. The end result of these effects, is smooth muscle and blood vessels are relaxed, allowing them to increase their diameter, opening up the flood gates for greater blood flow, greater amount of nutrient delivery, feeding, PRIMING and encouraging your muscles for muscular growth.

3.Antioxidant Blend
While exercise in itself is a great way to increase NO output, it also increases free radicals. Free radicals actually reduce NO levels, decreasing vasodialation, which of course is not what we want to happen during exercise. To counteract these free-radicals, we have included a specific array of antioxidants, which have actually been shown in research to protect NO from being broken down and deactivated by free-radicals. These anti-oxidants include, Grape seed extract(95% OPC), alpha-lipoic-acid(ALA) and folic-acid. Interesting, both ALA and folic-acid have been shown in research to additionally enhance eNOS(the enzyme that synthesizes NO)

[ATHLETIC EDGE NUTRITION]

Driving Intensity, Energy & Focus!

We all know how much our mental state affects our training. If your brain isn’t energized and focused and you don’t have the “muscle-mind connection”, muscular gains will plummet. How many times has your mind given up before your muscles have actually fatigued? If this is happening, you are NOT adequately stressing and overloading your muscles to a great enough degree to maximize muscular GROWTH.


Old School pre-workout formula- Rely on high amounts of stimulants, such as caffeine to drive the energy aspect of their formula. Most of the old school pre-workout formulas rely almost 100% on high amounts of caffeine and neglect the many other aspects of assisting the body to create, strong, clean energy, with zone like focus. Most of the products don’t even list the amount of caffeine in them. Since the energy, mind-muscle and focus aspects of PreSurge’s formula DO NOT rely on high amounts of caffeine to drive it, we are able to use a LOW amounts of caffeine and we LIST the amount (125mg) as well!


PreSurge Unleashed solution We target the mental/neurological aspects of training with our cutting edge, multi angle approach to bring you, a potent and plateau blasting energy/intensity blend that is designed to put you in the ZONE and keep you there throughout your workout.

1. L-theanine- L-theanine stimulates alpha wave activity in the brain and has been shown when combined with caffeine to be highly beneficial in improving speed, accuracy and alertness during demanding tasks. The ultimate combination for boosting neurological performance and the “mind muscle connection” that is crucially needed in the gym. Instead of using any cheap generic l-theanine, we went all out and licensed the exact same patented l- theanine(Suntheanin®) brand used in the research. And we dosed it in PreSurge to mimic the doses they found to be effective in the research. As an additional benefit, L-theanine has been shown in research to accelerate mental regeneration after exercise and reduce the negative side effects of caffeine. The perfect supplement to combat exercise induced neurological burnout that occurs to so many people when training hard and heavy. Additionally, it is the perfect addition to combat and offset potential burnout that can occur when using caffeine and the other stimulants contained in PreSurge. For more information and research on Suntheanine- http://www.suntheanine.com/

2. Neuravena- Another core ingredient of our intensity, energy, focus blend, is the brand new brain boosting ingredient Neuravena®. Neuravena is a wild green oat extract, that utilizes specific constituents of the plant that have a high degree of biological activity in relation to the two central nervous system enzymes, monoamine oxidase B(MAO-B) and phosphodiesterase 4(PDE 4). Research in humans has shown that Neuravena inhibits these two enzymes, which in turn will boost the neurotransmitter dopamine and the chemical messenger cyclic adenosine monophosphate(cAMP). The overall benefit of boosting these two are: enhanced alertness, greater energy and focus. The perfect mental state you need to be during your workout to push through plateaus.

3. To add some more grunt to the blend and to further crank up your energy and intensity levels, we added the energy boosters and neurotransmitter precursors, caffeine, theobromine, phenylethylamine (PEA), phenylalanine (DLPA) geranium (1,3-dimethylamylamine), tyrosine, taurine, TMG and evodiamine for the ultimate Pre-Workout energy blend.


Old School pre-workout formula- The dreaded mental and physical crash.

How often after just a few uses of your current pre-workout supplement, do you feel burned out, drained, apathetic and unable to function at an optimal level. The overall strength of the energy has largely decreased, forcing you to continuously increase your dosage to get any affect. And even then, the energy and focus, certainly isn’t as strong as it was the first few times? This usually occurs when formulas rely almost 100% on high amounts of caffeine and neglect the many other aspects of assisting the body to create, strong, clean energy, with zone like focus.

PreSurge Unleashed solution

PreSurge utilizes L-theanine, which has been shown in research to accelerate mental regeneration after exercise. The perfect supplement to combat at against neurological burnout that occurs to so many people when training hard and heavy. Additionally PreSurge Unleashed utilizes ingredients such as tyrosine, TMG, DLPA that are precursors that help rebuild depleted neurotransmitters that lead to the mental crash so common with old school formulas. The neurological regenerative approach to PreSurge’s formula, coupled with a low caffeine(125mg) content, make PreSurge the ultimate pre-workout weapon that will have you feeling good far beyond your workout and not dragging the next day.

Frequently asked questions

Q: Who can benefit from PreSurge Unleashed?
• Individuals participating in high- intensity strength- training programs looking to prime their muscles for GROWTH
• Individuals looking for big Pre-Workout increases in strength, Vascularity and intense mental energy and focus during their training
• Anyone looking to shatter training plateaus
• Anyone looking for the strength gains of creatine, without wanting all the sugar that is often loaded in creatine or pre-workout formulas.



Q: How will PreSurge Unleashed improve my workouts, maximizing my gains?

PreSurge works by flooding your body with the most potent combination of muscle building, nitric oxide boosting, muscular performance enhancing ingredients, supported by university research. Furthermore, PreSurge Unleashed is stacked with ingredients to prime and sensitize your muscles for maximum nutrient uptake, increased muscle hardness, fullness, vascularity and explosive pre-workout energy and intensity. PreSurge Unleashed creates the perfect anabolic environment for new muscle growth and plateau busting workouts…the perfect primer for IntrAbolic, our Phase-2: Intra-Workout Nutrient Timing Formula!


Q-Don’t I have to load up on creatine?

No, according to the research, you actually never had to and when a traditional loading phase (20g a day) was compared to much lower doses (3-6g a day), similar muscle creatine concentrations and performance increases were brought about, after 28 days of supplementation from both the 20g dose and the lower 3g dose. And there’s even less of a reason than ever to load, with PreSurge Unleashed utilizing Russian tarragon extract. More information below.

Q- Why didn’t AEN use some of the “supposedly superior forms of creatine, such as creatine ethyl ester (CEE)?

Because creatine monohydrate, has over 500 hundred peer reviewed, published studies to support it as an effective ergogenic aid. Take a guess how many published peer reviewed studies CEE has showing it effective? The answer, TWO and the first one showed its stability at various pH's to be greatly INFERIOR to creatine monohydrate and the other showed that it took four times as long as creatine monohydrate to significantly raise muscle creatine levels and it never was able to raise them as high due to a high conversion rate to creatinine. This study also, showed it converted to the waste product creatine, three times faster than mono. And lastly, it showed CEE caused a greater increase in extracellular water retention (BLOAT). Don't buy into pure marketing hype. Creapure is the KING of all creatine's.

For more information on Creapure- http://www.creapure.com/index.php?id=28\


Q- To maximize creatine’s absorption, don’t I need to consume it with simple sugars?

YES, you USED to, but not anymore, thanks to the inclusion of a specialized Russian Tarragon extract (Artemisia dracunculus L). This EXACT extract was recently shown in a study, combined with creapure creatine(the creatine we use in PreSurge Unleashed) to increase the uptake of creatine into skeletal muscle. The results were STAGGERING, showing this extract could bring about skeletal muscle absorption comparable to spiking insulin with large amounts of high glycemic carbohydrates and or protein. This specialized, Russian Tarragon extract will make your muscles like creatine sponges! Perfect for individuals looking to maximize muscle fullness and bring about ultra lean and hard looking muscles.

This is a HUGE breakthrough in the science of creatine supplementation and makes the consumption of huge amount of fat inducing, physique destroying simple sugars, a thing of the past.

[ATHLETIC EDGE NUTRITION]

Q: Do I need to add anything extra pre-workout to PreSurge to make it more effective?

NO, NOTHING else is necessary. After establishing your sensitivity to PreSurge Unleashed and if you find it necessary, you can increase to two servings. DO NOT EXCEED 3 servings. One to two servings will be enough for most individuals.

Q: Can I take PreSurge Unleashed late at night?
This is going to depend on your individual sensitivity to the ingredients in PreSurge. It is certainly possible that the strong stimulant aspect of PreSurge may adversely affect your sleep. We recommend if you work out late at night and are highly sensitive to stimulants such as caffeine, try taking a smaller dose. These questions can only fully be answered by your own trial and error as there is too much variability in stimulant sensitivity from individual to individual. As a general precaution, we suggest to not use PreSurge within 4-5 hours of bedtime.

Q: What other supplements do you recommend to maximize the results when taking PreSurge Unleashed?

While nothing extra is needed to be taken Pre-Workout, outside of PreSurge. There are other important formulas that were designed to be stacked with PreSurge that can greatly increase your overall gains in muscle mass and muscular performance and recovery.

• We recommend stacking PreSurge with our Phase-2: Intra-Workout Nutrient Timing Formula, IntrAbolic. PreSurge creates the perfect anabolic environment for new muscle growth and plateau busting workouts and is the perfect primer for IntrAbolic
• We recommend our beta-alanine, carnosine booster IntraXCell to be taken post-workout and on non training days to increase strength and endurance.
• Our full Triple Threat Nutrient Timing Stack™ is the most powerful stack in sports nutrition today.

Q: How should I combine these three products?

Our products are formulated based on the latest advancements in nutrient timing science and are designed to work together synergistically. To learn how to properly stack our products and maximize your muscle growth and performance, please read our Nutrient Timing Stack Recommendations below.

Triple Threat Nutrient Timing Stack™ Protocol- THE most powerful stack in sports nutrition today, PERIOD

PreSurge Unleashed, IntrAbolic & IntraXCell - This is our most powerful and effective stack, yielding the greatest results in building muscle mass, increasing performance and supercharging your energy and focus. This is the ultimate muscle building stack. This is perfection!

Pre-Workout ---1-3 servings of PreSurge Unleashed
Intra-Workout ---1-2 Servings of IntrAbolic
Post-Workout ---1 serving of IntraXCell
Non-training days ---2 servings of IntraXcell.Take each serving, preferably 3-4 hours apart and with meals



Recommended Use:
On Training days. For best results, take one to three servings in 8 to 24oz of water. Consume 20 to 30 minutes prior to exercise, preferably 1 to 1.5 hours after your last meal for the quickest absorption. PreSurge Unleashed is a incredibly strong formula and we HIGHLY recommend to start with one serving to assess your tolerance and work your way up to three servings if needed. Non-Training days: Taking PreSuge on non training days is optional but can help increase its benefits faster and increase your energy and focus throughout the day. To avoid building up a tolerance, we recommend discontinuing using PreSurge Unleashed every 12 weeks, for 2 to 4 weeks, before restarting to use it again for 12 weeks. DO NOT exceed more than 3 servings at one time or in a 24 hour period and do not use more than 5 days a week.



Products

IntraXCell-FAQ-THE DEFINITIVE Beta-Alanine Thread

IntrAbolic FAQ-THE Pioneer of Intra-Workout Supplementation

Our product summary review thread

Our Articles/Reviews:

Nutrient Timing Article in Muscular Development

Intra-workout Article in Muscular Development


IntraXCell sport supplement product review in Muscular Development

PreWo article and NEW beta-alanine article in Muscular Development

Beta-alanine article- science meets real world results, in Muscular Development

PreWO part two article

Beta-Alanine compared to creatine

Our beta-alanine article on bb.com

Intra-Workout threads
Comparing IntrAbolic to other products
Pick my next Intra-Workout product
Intra-Workout Ingredient Comparison
Best Intra-Workout Supplement
IntrAbolic Vs other Intra-Workout product
IntrAbolic VS other products



IntraXCell STUDY:
Beta-Alanine(IntraXCell) study

Radio interview on the Performance Nutrition radio show- http://www.performancenutritionshow....s/08_0921.html


Interview:
ATHLETIC EDGE NUTRITION interviews OLYMPIC hopeful Michael James!

[ATHLETIC EDGE NUTRITION]

2nd

Cant wait to try it!

lol. Sure thing

how about i show ya some of the upc's from my intrabolic tubs to show im a loyal user to get a trial package of presurge? and for helping make your job easier and deleting my post

Ok, I'm done. If you guys could delete your above posts, we're all set and you can start posting as normal.

Appreciated

[donoh]

Can't wait to try this out

[ericescobar15]

can i get a free package brah. kthanks!

[jeremyleinen]

i was really excited about this until i saw the geranium. count me out.

[Chimpinzo]

Any ingredients panel by chance Or an eta on when one would be available?

[papagunz]

i was really excited about this until i saw the geranium. count me out.

I'd have to try it. I have had some of my best workouts with 1,3 in my system, and some of the worst workouts with 1,3 in my system. Even something like a cup of tea or coffee HOURS before ingesting a preworkout drink with 1,3 can fubar me.

[jeremyleinen]

I'd have to try it. I have had some of my best workouts with 1,3 in my system, and some of the worst workouts with 1,3 in my system. Even something like a cup of tea or coffee HOURS before ingesting a preworkout drink with 1,3 can fubar me.

I have phenomenal workouts with it... no question about that. Its just not worth being useless for the rest of the day because of how hard I crash from it.

[NasGhost]

2 questions for you Seb

1) When do I get a free tub for free because I asked nicely (jk lol)
2) Will there actually be a "Triple Threat Nutrient Timing Stack" sold here on bb.com?

[Achilles_1986]

I just placed an order and what do you know PreSurge finally comes out. Well maybe after my creatine mono, Cit Malate, Intrabolic run is over it will be ready and in stock so I start my AEN stack and love affair.

Edit- I see Intracell is finally back in stock. "thumbs up"

[papagunz]

I have phenomenal workouts with it... no question about that. Its just not worth being useless for the rest of the day because of how hard I crash from it.

I hear you. There are times when it feels like I smoked an entire baggie to myself during a 1,3 crash. **** is rough.

[Achilles_1986]

BTW Seb, when you get the chance now that you are done with PreSurge and all can you email me that leg workout we talked about awhile back?? Not sure if you even remember lol.

[moondg29]

Wow. This looks amazing if the ingredients are dosed well.

[mendozaj]

Will def pick up a tub when it comes out looks solid but, can i haz some samples good sir? Okthnxbye

[Panabol]

Wow, was looking for something like this...creatine but low carbs. Gotta get some samples before use but

[StringerrBell]

Release date?

[vsev12]

Looks like a solid profile, excited about addition of 1,3 .. now can only hope that I will need less than 3 servings / workout, as it wouldnt be very good value in that case. Considering I have to uncap + mix with malto 10-12 presurge caps to get a good effect, its not looking very promising.

Still count me in for a tub or two (or max PIITB on wheycheap )

[Striver]

Oh god I want it. I SHALL HAVE IT!

[ATHLETIC EDGE NUTRITION]

Any ingredients panel by chance Or an eta on when one would be available?

Shortly but most are all listed in the write-up above.

I'd have to try it. I have had some of my best workouts with 1,3 in my system, and some of the worst workouts with 1,3 in my system. Even something like a cup of tea or coffee HOURS before ingesting a preworkout drink with 1,3 can fubar me.

I am the same way, which is one reason it never found its way in the origional PreSurge. But PreSurge Unleashed, with l-theanine, Neuravna, tyrosine and more is VERY different from any 1,3 containing product you've ever felt.

I have phenomenal workouts with it... no question about that. Its just not worth being useless for the rest of the day because of how hard I crash from it.

When I first starting using it years ago, I would literally have to go lay down in my bed as I started coming down.

I really feel the l-theanine, tyrosine, neuravena and others and the ways its dosed, greatly reduces or compleatly avoids the crash.

2 questions for you Seb

1) When do I get a free tub for free because I asked nicely (jk lol)
2) Will there actually be a "Triple Threat Nutrient Timing Stack" sold here on bb.com?

1. I don't even know if we have enough tubs to do any logs
2. Yes!

I just placed an order and what do you know PreSurge finally comes out. Well maybe after my creatine mono, Cit Malate, Intrabolic run is over it will be ready and in stock so I start my AEN stack and love affair.

Edit- I see Intracell is finally back in stock. "thumbs up"

Yes, IntraXCell is back in stock, finally!

BTW Seb, when you get the chance now that you are done with PreSurge and all can you email me that leg workout we talked about awhile back?? Not sure if you even remember lol.

Can you email and remind me?

Wow. This looks amazing if the ingredients are dosed well.

Will def pick up a tub when it comes out looks solid but, can i haz some samples good sir? Okthnxbye

Samples are all going to stores and demos.

Wow, was looking for something like this...creatine but low carbs. Gotta get some samples before use but

Yes, 2g of carbs and russian tarragon extract for creatine uptake

Release date?

I hope it will be up in bb.com's late this week/early next but that's up to them.

Looks like a solid profile, excited about addition of 1,3 .. now can only hope that I will need less than 3 servings / workout, as it wouldnt be very good value in that case. Considering I have to uncap + mix with malto 10-12 presurge caps to get a good effect, its not looking very promising.

Still count me in for a tub or two (or max PIITB on wheycheap )

PreSurge and PreSurge Unleashed can't be compared serving to serving in terms of stim/energy aspect.

I look forward to your feedback.

Oh god I want it. I SHALL HAVE IT!

Low price as well!

[bobcat11]

wow, if i could make my own pre-wo it would pretty much be this. cant wait. where can i get samples?

[Mata Leao]

cool in again.. been a fan ever since the early days and im still a loyal customer.. i even remember steel edge... used to take it all the time.... now intrabolic and presurge are a staple..

so is this unleashed gonna be released on pill form?

either way will buy it as soon as it comes out.

[ATHLETIC EDGE NUTRITION]

wow, if i could make my own pre-wo it would pretty much be this. cant wait. where can i get samples?

Pretty much all the samples are being sent to stores and for demos.

cool in again.. been a fan ever since the early days and im still a loyal customer.. i even remember steel edge... used to take it all the time.... now intrabolic and presurge are a staple..

so is this unleashed gonna be released on pill form?

either way will buy it as soon as it comes out.

We're working on that yes but no ETA. We also have many other projects in the works for this year.....

[Madevilz]

We also have many other projects in the works for this year.....

I like the sound of that.

[ATHLETIC EDGE NUTRITION]

I like the sound of that.

Yeah, new products, more flavors of PreSurge Unleashed. This year is going to be crazy for us!

[ATHLETIC EDGE NUTRITION]

Some l-theanine(Suntheanine) research and how it perfectly fits in with the PreSurge formula, to enhance cognitive function, focus, enhance caffeine, reduce caffeine's side effects and fight neurological burnout. Could their be a more PERFECT addition to PreSurge!?

Improving mental regeneration after physical exercise

Ralf Jäger1 , Martin Purpura1, Kurt-Reiner Geiss2, Thorsten Barthel3, Reinhard Schnittker3 and Michael Weiß3 1Increnovo LLC, 2138 E Lafayette Pl, Milwaukee, WI 53202, USA
2ISME, Weingartenstr. 2, 64546 Mörfelden-Walldorf, Germany
Journal of the International Society of Sports Nutrition 2008, 5(Suppl
Published: 17 September 2008


Background
Nutritional interventions to improve physical regeneration after exercise are usual practice among recreational and professional athletes. Frequent strategies include rehydration, in addition to supplementation with macronutrients to replenish depleted glycogen stores, or to support muscle growth and/or maintenance. Physically challenging exercise results in a significant activation of brain activity and no nutritional strategies have yet been developed to improve mental regeneration after exercise. L-Theanine, an amino acid found in green tea leaves, might be able to improve mental regeneration since it has been linked to reducing mental stress and having relaxing effects. A randomized, double-blind, placebo-controlled, crossover study was performed to evaluate the effects of 50 or 200 mg L-theanine supplementation on mental regeneration and hormonal response to physical exercise.

Methods
The individual working capacity of 14 healthy male subjects (age 24.5 +/- 2.4 years, height 181.2 +/- 4.9 cm, weight 78.8 +/- 9.7 kg) was evaluated in a pretest using a bicycle ergometer test. Starting at 50 Watt, the workload increased every 3 minutes until exhaustion. The maximal individual workload (mean 357 +/- 47 Watt) that could be maintained for 3 minutes in the pretest was used as the upper limited during a 16-minute exercise. One hour after a standardized breakfast (395 kcal, 50 g carbohydrates, 18.4 g fat, 7.6 protein) exercise started at 20% of the maximal individual workload. The intensity was gradually increased every 3 minutes, with the fifth interval (maximum workload) lasting 4 minutes. Thirty minutes after the start of exercise the subjects received a 330 ml beverage containing 50 or 200 mg of L-theanine or placebo. The subjects recovered passively lying in a shaded room and topographical frequency spectrum electroencephalography (EEG) mapping, heart rate, blood pressure, leukocytes, blood glucose and stress hormone levels were measured one minute after workout and 30, 45, 60 and 120 minutes after the consumption of the beverage. The three tests were separated by one week each.
Results
Analysis of alpha-, beta- and delta frequencies showed dominating high frequencies bands and high activity immediately after exercise. A shift to lower frequencies and a decrease in power were observed during the recovery phase. L-Theanine supplementation did not change the natural down regulation pattern; however, it resulted in an earlier onset of mental regeneration in comparison to placebo. Fifty mg L-theanine resulted in a significant reduction of alpha 2 power already 30 minutes after the consumption of the beverage (-50%, -19% with placebo), and continued to show improvements over placebo at later measurements (45 min: -49%, -39% with placebo). Supplementation with 200 mg L-theanine demonstrated no additional benefit. Exercise resulted in increased levels of leukocytes, blood glucose, catecholamines, serotonin and dopamine directly after workout, and increased concentrations of cortisol and prolactin at 44 and 59 minutes after exercise. All blood parameters returned to normal values after 2 hours of recovery. Maximal mean heart rate (186 +/- 9 bpm) and blood pressure quickly returned to resting values after exercise. MANOVA (level of significance p < 0.05) showed significant changes with time of any blood parameter, however, showed no differences between the different treatment groups.

Conclusion
It is concluded that post-workout supplementation of 50 mg L-theanine accelerates mental regeneration after physical exercise. The effect is not based on hormonal changes and higher amounts of L-theanine do not result in additional benefits.



Psychological effects of dietary components of tea: caffeine and L-theanine.
Nutr Rev. 2008 Feb;66(2):82-90.Bryan J.School of Psychology, University of South Australia, Adelaide, 5001, South Australia, Australia.

This review summarizes the literature on the association between two dietary components of tea, caffeine and L-theanine, and the psychological outcomes of consumption; it also identifies areas for future research. The studies reviewed suggest that caffeinated tea, when ingested at regular intervals, may maintain alertness, focused attention, and accuracy and may modulate the more acute effects of higher doses of caffeine. These findings concur with the neurochemical effects of L-theanine on the brain. L-theanine may interact with caffeine to enhance performance in terms of attention switching and the ability to ignore distraction; this is likely to be reflective of higher-level cognitive activity and may be sensitive to the detrimental effects of overstimulation. Further research should investigate the interactive effects of caffeine, L-theanine, and task complexity, utilize a range of ecologically valid psychological outcomes, and assess the neuroprotective effects of L-theanine using epidemiological or longer-term intervention studies among individuals at risk of neurodegenerative disease. PMID: 18254874 [PubMed - indexed for MEDLINE]



L-theanine, a natural constituent in tea, and its effect on mental state.
Asia Pac J Clin Nutr. 2008;17 Suppl 1:167-8.
Nobre AC, Rao A, Owen GN.Unilever Food and Health Research Institute, Olivier van Noortlaan 120, Postbus 114, 3130 AC Vlaardingen, The Netherlands.

Tea is the most widely consumed beverage in the world after water. Tea is known to be a rich source of flavonoid antioxidants. However tea also contains a unique amino acid, L-theanine that may modulate aspects of brain function in humans. Evidence from human electroencephalograph (EEG) studies show that it has a direct effect on the brain (Juneja et al. Trends in Food Science & Tech 1999;10;199-204). L-theanine significantly increases activity in the alpha frequency band which indicates that it relaxes the mind without inducing drowsiness. However, this effect has only been established at higher doses than that typically found in a cup of black tea (approximately 20mg). The aim of the current research was to establish this effect at more realistic dietary levels. EEG was measured in healthy, young participants at baseline and 45, 60, 75, 90 and 105 minutes after ingestion of 50mg L-theanine (n=16) or placebo (n=19). Participants were resting with their eyes closed during EEG recording. There was a greater increase in alpha activity across time in the L-theanine condition (relative to placebo (p+0.05). A second study replicated this effect in participants engaged in passive activity. These data indicate that L-theanine, at realistic dietary levels, has a significant effect on the general state of mental alertness or arousal. Furthermore, alpha activity is known to play an important role in critical aspects of attention, and further research is therefore focussed on understanding the effect of L-theanine on attentional processes.PMID: 18296328 [PubMed - indexed for MEDLINE]



The combined effects of L-theanine and caffeine on cognitive performance and mood.
Nutr Neurosci. 2008 Aug;11(4):193-8. Owen GN, Parnell H, De Bruin EA, Rycroft JA.Unilever Research and Development, Colworth House, Sharnbrook, Bedford, UK.

The aim of this study was to compare 50 mg caffeine, with and without 100 mg L-theanine, on cognition and mood in healthy volunteers. The effects of these treatments on word recognition, rapid visual information processing, critical flicker fusion threshold, attention switching and mood were compared to placebo in 27 participants. Performance was measured at baseline and again 60 min and 90 min after each treatment (separated by a 7-day washout). Caffeine improved subjective alertness at 60 min and accuracy on the attention-switching task at 90 min. The L-theanine and caffeine combination improved both speed and accuracy of performance of the attention-switching task at 60 min, and reduced susceptibility to distracting information in the memory task at both 60 min and 90 min. These results replicate previous evidence which suggests that L-theanine and caffeine in combination are beneficial for improving performance on cognitively demanding tasks.PMID: 18681988 [PubMed - indexed for MEDLINE]


The effects of L-theanine, caffeine and their combination on cognition and mood.
Biol Psychol. 2008 Feb;77(2):113-22. Epub 2007 Sep 26.Haskell CF, Kennedy DO, Milne AL, Wesnes KA, Scholey AB.
Human Cognitive Neuroscience Unit, Division of Psychology, Northumbria University, Newcastle upon Tyne NE1 8ST, UK.

L-Theanine is an amino acid found naturally in tea. Despite the common consumption of L-theanine, predominantly in combination with caffeine in the form of tea, only one study to date has examined the cognitive effects of this substance alone, and none have examined its effects when combined with caffeine. The present randomised, placebo-controlled, double-blind, balanced crossover study investigated the acute cognitive and mood effects of L-theanine (250 mg), and caffeine (150 mg), in isolation and in combination. Salivary caffeine levels were co-monitored. L-Theanine increased 'headache' ratings and decreased correct serial seven subtractions. Caffeine led to faster digit vigilance reaction time, improved Rapid Visual Information Processing (RVIP) accuracy and attenuated increases in self-reported 'mental fatigue'. In addition to improving RVIP accuracy and 'mental fatigue' ratings, the combination also led to faster simple reaction time, faster numeric working memory reaction time and improved sentence verification accuracy. 'Headache' and 'tired' ratings were reduced and 'alert' ratings increased. There was also a significant positive caffeine x L-theanine interaction on delayed word recognition reaction time. These results suggest that beverages containing L-theanine and caffeine may have a different pharmacological profile to those containing caffeine alone.PMID: 18006208 [PubMed - indexed for MEDLINE]


WAY MORE RESEARCH on SUNTHEANINE- http://www.suntheanine.com/Research.cfm

[DGreekStallion]

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[ATHLETIC EDGE NUTRITION]

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