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  1. #1
    Hyper for teh trophy LdnLifter's Avatar
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    Link between drinking milk and increase in igf 1 production

    I keep hearing drinking milk increases igf 1 production.

    Can someone link me to reasearch which indentifies/links between milk and igf 1 production.
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    work in progress IGF-WON's Avatar
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    correct me if im wrong, but doesnt milk have IGF-1 in it?
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    :S i havent heard about igf1 production from milk :S

    Weird. I easily drink a minimum of 6 UK pints a day too.
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    nevigsawkufelgnisaton in10city's Avatar
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    Originally Posted by LdnLifter View Post
    I keep hearing drinking milk increases igf 1 production.

    Can someone link me to reasearch which indentifies/links between milk and igf 1 production.
    I'll post up some info later is someone else doesn't. You can go here and search as well: http://www.ncbi.nlm.nih.gov/sites/entrez

    If you can get your hands on the Feb-08 issue of Muscular Development, there is an article in it.
    Last edited by in10city; 05-29-2008 at 09:19 AM.
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    Hyper for teh trophy LdnLifter's Avatar
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    Originally Posted by in10city View Post
    I'll post up some info later is someone else doesn't. You can go here and search as well: http://www.ncbi.nlm.nih.gov/sites/entrez
    ok thanks
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    Registered User FlyingIllini's Avatar
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    So what are the consequences of getting IGF-1 from milk for bodybuilders ?
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    Originally Posted by FlyingIllini View Post
    So what are the consequences of getting IGF-1 from milk for bodybuilders ?
    maybe youll get big? google IGF-1 and see what you learn
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    Hyper for teh trophy LdnLifter's Avatar
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    Originally Posted by FlyingIllini View Post
    So what are the consequences of getting IGF-1 from milk for bodybuilders ?
    * Stimulates muscle growth and has been shown to benefit the heart (a muscle).
    * Encourages the absorption of Chondroitin Sulfate and Glucosamine Sulfate (also found in Velvet Antler).
    * Regenerates nerve tissue
    * Helps burn fat, increase protein transport into cells, and reduce protein breakdown
    * Improves the production of white blood cells
    * Decreases LDL Cholesterol
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    Registered User djansen's Avatar
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    So whats the deal with lycopene and IGF-1? if I have a glass of milk pwo and some spuds with ketchup with it am I negating the IGF-1?
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    nevigsawkufelgnisaton in10city's Avatar
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    Originally Posted by djansen View Post
    So whats the deal with lycopene and IGF-1? if I have a glass of milk pwo and some spuds with ketchup with it am I negating the IGF-1?
    The chances of fruits/veggies or even supplements doing anything to serum IGF-1 are slim if you are healthy.
    Last edited by in10city; 04-01-2010 at 05:19 PM.
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    Does it matter if it is whole milk, 1%, 2%, or fat free. I am on a cut and Im only drinking water and protein shakes so I am wondering if adding fat free milk to my diet would benefit me???
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  12. #12
    Registered User djansen's Avatar
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    Originally Posted by in10city View Post
    The chances of fruits/veggies or even supplements doing anything to serum IGF-1 are slim if you are healthy.
    Thanks! so the talk about milk leading to higher IGF-1 are pretty hyped up like most everything lol?
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  13. #13
    Registered User Rogues's Avatar
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    I believe it's the casein that does it.
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    nevigsawkufelgnisaton in10city's Avatar
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    Originally Posted by djansen View Post
    Thanks! so the talk about milk leading to higher IGF-1 are pretty hyped up like most everything lol?
    Milk does appear to increase serum IGF-1, but the significance/correlations of changes in circulating IGF-1 and muscle growth is debatable. The confusion with IGF-1 arises because the collective "IGF-1" actually exists as several different splice variants and is produced in various tissues such as the liver (systemic/ circulating for endocrine action) and in other tissue like muscle (locally produced for autocrine / paracrine action and typically doesn't significantly contribute to what shows up in circulation). It is the locally produced IGF-1 isoforms that appear to have stronger correlations with muscle mass, hypertrophy, and cell repair while high or low circulating IGF-1 is often correlated to the risk of a number of pathological conditions and disease lol. Nonpharmacologically boosting local IGF-1, which creatine and exercise and muscle overload do > boosting circulating IGF-1.
    Last edited by in10city; 04-02-2010 at 07:54 AM.
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    Registered User djansen's Avatar
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    Originally Posted by in10city View Post
    Milk does appear to increase serum IGF-1, but the significance/correlations of changes in circulating IGF-1 and muscle growth is debatable. The confusion with IGF-1 arises because the collective "IGF-1" actually exists as several different splice variants and is produced in various tissues such as the liver (systemic/ circulating for endocrine action) and in other tissue like muscle (locally produced for autocrine / paracrine action and typically doesn't significantly contribute to what shows up in circulation). It is the locally produced IGF-1 isoforms that appear to have stronger correlations with muscle mass, hypertrophy, and cell repair while high or low circulating IGF-1 is often correlated to the risk of a number of pathological conditions and disease lol. Nonpharmacologically boosting local IGF-1, which creatine and exercise and muscle overload do > boosting circulating IGF-1.
    hmmm, I love when you read something and like that milk raises IGF-1 and that source fails to tell you the real story. thanks for clearing this up! so in a sense there are "forms" if you will of IGF-1?
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    nevigsawkufelgnisaton in10city's Avatar
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    Originally Posted by djansen View Post
    hmmm, I love when you read something and like that milk raises IGF-1 and that source fails to tell you the real story. thanks for clearing this up! so in a sense there are "forms" if you will of IGF-1?
    The IGF-1 gene can transcribe multiple mRNA variants which include IGF-1Ea, IGF-1Eb and IGF-1Ec, that when translated (synthesis of the pre-pro-IGF-1 precursor peptide from the mRNA) and post-translationally modified all yield the same mature IGF-1 peptide/hormone but 3 different E-peptides. Most actions are mediated through mature IGF-1 but the Ec peptide (or a part of it) which is often referred to as endogenous mechano-growth factor (MGF) may have some additional effects. There is some debate as to whether or not endogenous MGF has the same effects seen with synthetic MGF or if they are even molecularly the same.
    Last edited by in10city; 04-02-2010 at 04:22 PM.
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