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  1. #1
    Registered User Xpiro's Avatar
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    Huperzine-A + Choline

    So I was gifted a tub of C4 Ultimate Shred, which contains Huperzine-A and Alpha-GPC. From what I understand, I Hup-A increases concentrations of choline, which in the context of this pre workout alone is probably fine, but the pre I’m already taking has 500mg of Choline bitartrate. I’m finding that choline has a half life of about 3 days... could switching to C4 too soon after my last dose of my normal pre-workout cause concentrations to become too high = negative side effects? Should I give it 3 days? Vice versa as well if I don’t care for the C4 and want to go back to my regular stuff. It was free, so....
    Last edited by Xpiro; 02-03-2021 at 09:21 PM.
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  2. #2
    It's pronounced gif eatyourspinach's Avatar
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    It's questionable how much choline bitartrate crosses the blood brain barrier, since you haven't been taking huperzine previously you should be fine but you'd be able to tell if you were taking too many cholinergics before any really bad sides
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  3. #3
    Registered User Xpiro's Avatar
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    “you'd be able to tell if you were taking too many cholinergics before any really bad sides”

    What do you mean?
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    It's pronounced gif eatyourspinach's Avatar
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    Originally Posted by Xpiro View Post
    “you'd be able to tell if you were taking too many cholinergics before any really bad sides”

    What do you mean?
    you'd get brain fog, feel depressed etc.
    My secret? Texting between sets.
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    Registered User stad0203's Avatar
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    OP thanks for giving C4 a shot. I think in this instance as stated above you'd be fine but if you are worried just space them out a couple days.

    Let us know how you like it!
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    Registered User ManwittaPlan's Avatar
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    Originally Posted by Xpiro View Post
    So I was gifted a tub of C4 Ultimate Shred, which contains Huperzine-A and Alpha-GPC. From what I understand, I Hup-A increases concentrations of choline, which in the context of this pre workout alone is probably fine, but the pre I’m already taking has 500mg of Choline bitartrate. I’m finding that choline has a half life of about 3 days... could switching to C4 too soon after my last dose of my normal pre-workout cause concentrations to become too high = negative side effects? Should I give it 3 days? Vice versa as well if I don’t care for the C4 and want to go back to my regular stuff. It was free, so....
    if they contain both the huperzine and especially the alpha gpc which has been shown in MANY studies as a legit ergogenic aid, it's a winner.

    i actually had to stop using both (even though they were my favorite) because i was taking in way too many nootropics which led to anxiety attacks. as soon as i stopped symptoms went away. i guess you casn say the alpha gpc worked too well, use it sparingly or for days when you need a new PR.

    there is good reason jim stoppani, paul chek, charles poliquin and tim ferris were all big fans of alpha gpc well over a decade ago.
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