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    You’re going back and forth between two separate...

    You’re going back and forth between two separate but interconnected topics.
    What you’re talking about is targeting conserved regions. In evolutionary biology we can test for positive selection (we...
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    You should’ve taken my course instead. I could’ve...

    You should’ve taken my course instead. I could’ve conveyed the principle so you actually understood it.

    It’s a life history trade off. Higher exploitation brings with it higher within host...
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    Not really how it works for leaky vaccines. I’m...

    Not really how it works for leaky vaccines. I’m intimately familiar with Read’s work. He actually came out and gave an interview because his work was being misconstrued. Ironically, the very argument...
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    They’re probably still having some effect on...

    They’re probably still having some effect on transmission, admittedly less than for previous variants.

    The vaccines may reduce the risk of a virulent variant in other ways, too. Reducing overall...
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    Which is certainly possible. This virus is still...

    Which is certainly possible. This virus is still generating a great deal of genetic variation. I won’t go as far as saying that it’s likely, but I wouldn’t be surprised if we see a more virulent and...
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    You have the vaccines to thank, partly, for...

    You have the vaccines to thank, partly, for Omicron’s mildness.

    There are numerous studies suggesting that the vaccines are effective against severe disease with Omicron. With a booster, they are...
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    Quoting this for yet another example of an anti...

    Quoting this for yet another example of an anti vax idiot not being able to interpret a table.
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    Solid post

    Solid post
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    Apologies. Just realized they’re not working...

    Apologies. Just realized they’re not working anymore.
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    There are studies that have looked specifically...

    There are studies that have looked specifically at Delta. Most have shown a relative reduction in infection between 40-60%, similar to what you posted. Here are a few.

    ...
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    Who is they? The referenced study isn’t from...

    Who is they? The referenced study
    isn’t from the CDC. From the article itself:

    “The U.S. Centers for Disease Control and Prevention, for instance, doesn't have good data on how many people...
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    Innate =\= t-cell. Perhaps you meant myeloid, but...

    Innate =\= t-cell. Perhaps you meant myeloid, but even that isn’t entirely correct.

    Anyways, there is no chance that humoral responses are not playing a protective role. These are not mutually...
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    Hope he pulls through. Sad stuff.

    Hope he pulls through. Sad stuff.
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    Disease severity can be influenced by the initial...

    Disease severity can be influenced by the initial dose of the pathogen in the inoculum. Animal models have demonstrated this for a wide array of pathogens. The route of transmission is also...
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    Yes, some vaccines are intended to work that way....

    Yes, some vaccines are intended to work that way. Many anti-toxin vaccines are anti-disease with small impacts on transmission. Natural infection doesn’t always induce sterilizing immunity either,...
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    Yes they are. A multitude of studies have...

    Yes they are. A multitude of studies have demonstrated that even against delta, effectiveness against severe disease is ~90% for the mRNA vaccines. That is highly effective, and that aspect has waned...
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    Yup, growing body of evidence that SARSCOV2 has...

    Yup, growing body of evidence that SARSCOV2 has evolved to be more exploitative and virulent since the ancestral variant. Contrary to popular opinion, which I’ve tried to correct repeatedly,...
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    The vaccines are working wonderfully. The mRNA...

    The vaccines are working wonderfully. The mRNA vaccines still offer great protection against severe disease and death. That aspect is holding more constant than effectiveness against infection, which...
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    For anyone interested, this is a cool study....

    For anyone interested, this is a cool study. First of its kind that I’m aware of. Shows that vaccination induces acutely higher levels of antibodies than infection (we knew this) but that they wane...
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    That’s what I like to hear.

    That’s what I like to hear.
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