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Some colleagues recently published this pre-print (meaning it has yet to complete peer-review), but the results are timely to current discussions:
[url]https://www.medrxiv.org/content/10.1101/2021.10.13.21264957v1[/url]
[B]Findings[/B]
We estimate that two standard doses of either mRNA-1273 or BNT162b2, with dosage times separated by the company-mandated intervals, results in individuals loosing more than 99% humoral immunity relative to peak immunity by eight months following the second dose. We predict that within an eight month period following dose two (corresponding to the CDC time-frame for administration of a third dose), there exists a period of time longer than one month where an individual has less then 99% humoral immunity relative to peak immunity, regardless of which vaccine was administered. We further find that age has a strong influence in maintaining humoral immunity; by eight months following dose two we predict that individuals aged 18-55 have a four-fold humoral advantage compared to aged 56-70 and 70+ individuals. We find that sex has little effect on the vaccine uptake and long-term IgG counts. Finally, we find that humoral immunity generated from two low doses of mRNA-1273 decays substantially slower relative to peak immunity gained than compared to two standard doses of either mRNA-1273 or BNT162b2.
[B]Interpretation[/B]
For the two dose mRNA vaccines, our predictions highlight the importance of the recommended third booster dose in order to maintain elevated levels of antibodies. We further show that age plays a critical role in determining the antibody levels. Hence, a third booster dose may confer an immuno-protective advantage in older individuals.
[B]Funding[/B]
This research is supported by NSERC Discovery Grant (RGPIN-2018-04546), NSERC COVID-19 Alliance Grant ALLRP 554923-20, CIHR-Fields COVID Immunity Task Force, NRC Pandemic Response Challenge Program Grant No. PR016-1.
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[QUOTE=ajdahlheimer;1649283793]This isn't meant to be a pro or anti-vax argument, just something I wanted to share. I have kids in 8th, 10th, and 11th grade. At the beginning of the year, the school board decided that the kids must wear masks in schools as long as the 7-day-infection rate for county remained higher than 50 per 100k people. So I've obviously kept my eye on this rate this whole school year. It has steadily risen from 94 in August to currently 261. i.e. heading the wrong direction for the kids to not have to wear masks. Anyway, many of you probably don't know that I'm a bit of a math nerd (was a mathematics major in college)-so I decided to dive into the calculations a little bit-to try and figure out how this number could keep getting bigger and bigger despite the vaccination rate in the county steadily climbing as well (it is currently 70.4% in the county for kids over 12 years old).
Currently breakthrough infections account for 1/3 of all new the positive cases in MN, but they are put into the same bucket as unvax’d positives when calculating infection rate.
If you look at what that current 7-day-infection-rate of 261 actually means for the county which has 440k people, it means about 1150 people in the county got the virus last that week. You divide that by 4.4 to get the per 100k people number which is the 261. So anyway, just working backwards you can figure out just how LOW overall infections would need to get in order to get below that <50 threshold—which is just 49×4.4=215 total infections per week. Breakthrough cases are easily going to hit that infections total regardless of vaccination rate—so they basically gimmick’d the thing from the start by picking a number that there was a mathematical certainty to never hit (whether they actually realized it or not at the time).
To conclude, the kids won’t ever actually be out of masks until the school board changes that 50 cases per 100k threshold. Basically, by telling parents/kids to keep an eye on that 7-day-rate—-they are telling people to watch a clock and wait for it to strike "13 o’clock". That is pretty messed up and the kind of lack of transparency that just creates more gov’t distrust.
You don’t have to be a mathematician to do these basic calculations, but most people won’t take the time to do so—-and will just believe the threshold the gov’t quotes is actually "achievable".[/QUOTE]
[QUOTE=ajdahlheimer;1649284873]Well for starters, I wouldn't bucket the breakthrough infections into the same pool as the positive infections for unvax'd individuals. Doing so is essentially "stuffing the box" to keep that rate high. And this is despite the fact the vast majority of breakthrough infections are asymptomatic. That action alone would at least provide a somewhat "relevant" rate to what is actually occurring for community spread.
There is so much misinformation or misinterpreted information out there as it pertains to breakthrough infections. The number we keep hearing is "1.4%". But it's 1.4% of the entire vaccinated group that will get infected. Not 1.4% of current infections. So when you read a headline that says "2,000 new covid infections in MN"--most people think only 1.4% of those 2,000 were vaccinated people. When in reality 36% of those 2,000 were vaccinated/breakthrough cases. So 720 people instead of 28. Kind of a big difference, don't you think?
3.2 million people in MN have been vaccinated. 1.4% of that number is a lot people. Now factor in that the majority of the population lives in the Twin Cities metro area as opposed to the rural areas. Breakthrough cases will keep the infection rate well above these mandate thresholds indefinitely. It is a mathematical certainty.[/QUOTE]
Awesome stuff. There has been and continues to be a lot of misinformation from what should be credible sources. While not lying per se, it intentionally misrepresents information. We are under a 2% positivity rate and our fat slob governor just extended emergency orders and refuses to even identify a marker when restrictions will be lifted. It almost seems like their are motivators other than covid…
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[QUOTE=TryingBB;1649358413]Don’t want to turn this into a debate - that was my opinion and no one has to agree with it.
*****
Good for ya! I didn’t mean it like that. I meant about kids in general but yea maybe it’s projection. I’ll have to think about it. Regardless what I said holds true - also, new “normal” precisely means adapting imo
Teaching “life isn’t fair” at a very early stage may instill hatred and selfishness into a child’s mind (which is definitely needed in life @ at the right time), but it’s your kids. You do you.[/QUOTE]
Or different take - teaching them life isn't fair will teach them they aren't entitled, to adapt to their situation and to not complain or compare their situations to others. Not to mention its not like I don't work on other life lessons in conjunction like empathy, compassion for others, service to those not as fortunate etc. But you do you too.
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[img]https://i.imgur.com/TK6T71e.jpg[/img]
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A woman brought a very limp duck into a veterinary surgeon. As she laid her pet on the table, the vet pulled out his stethoscope and listened to the bird's chest. After a moment or two, the vet shook his head and sadly said, "I'm sorry, your duck has passed away."
The distressed woman wailed, "Are you sure?" "Yes, I am sure. Your duck is dead," replied the vet.
"How can you be so sure?" she protested. "I mean you haven't done any testing on him or anything. He might just be in a coma or something."
The vet rolled his eyes, turned around and left the room. He returned a few minutes later with a black Labrador.
As the duck's owner looked on in amazement, the dog stood on his hind legs, put his front paws on the examination table and sniffed the duck from top to bottom. He then looked up at the vet with sad eyes and shook his head. The vet patted the dog on the head and took it out of the room. A few minutes later he returned with a cat. The cat jumped on the table and also delicately sniffed the bird from head to foot. The cat sat back on its haunches, shook its head, meowed softly and strolled out of the room.
The vet looked at the woman and said, "I'm sorry, but as I said, this is most definitely, 100% certifiably, a dead duck."
The vet turned to his computer terminal, hit a few keys and produced a bill, which he handed to the woman.
The duck's owner, still in shock, took the bill. "$1500!" she cried, "$1500 just to tell me my duck is dead!"
The vet shrugged, "I'm sorry. If you had just taken my word for it, the bill would have been $100, but with the Lab Report and the Cat Scan, it's now $1500."
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[QUOTE=Plateauplower;1649388343]A woman brought a very limp duck into a veterinary surgeon. As she laid her pet on the table, the vet pulled out his stethoscope and listened to the bird's chest. After a moment or two, the vet shook his head and sadly said, "I'm sorry, your duck has passed away."
The distressed woman wailed, "Are you sure?" "Yes, I am sure. Your duck is dead," replied the vet.
"How can you be so sure?" she protested. "I mean you haven't done any testing on him or anything. He might just be in a coma or something."
The vet rolled his eyes, turned around and left the room. He returned a few minutes later with a black Labrador.
As the duck's owner looked on in amazement, the dog stood on his hind legs, put his front paws on the examination table and sniffed the duck from top to bottom. He then looked up at the vet with sad eyes and shook his head. The vet patted the dog on the head and took it out of the room. A few minutes later he returned with a cat. The cat jumped on the table and also delicately sniffed the bird from head to foot. The cat sat back on its haunches, shook its head, meowed softly and strolled out of the room.
The vet looked at the woman and said, "I'm sorry, but as I said, this is most definitely, 100% certifiably, a dead duck."
The vet turned to his computer terminal, hit a few keys and produced a bill, which he handed to the woman.
The duck's owner, still in shock, took the bill. "$1500!" she cried, "$1500 just to tell me my duck is dead!"
The vet shrugged, "I'm sorry. If you had just taken my word for it, the bill would have been $100, but with the Lab Report and the Cat Scan, it's now $1500."[/QUOTE]
Thanks Bro, I needed that. :)
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Johns Hopkins weekly briefing on Covid
[youtube]hnczBl79ygc[/youtube]
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[img]https://i.imgur.com/TcgH3bP.jpg[/img]
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At least three of my ex coworkers are not being called back to work cos they're not vaxxed. One is still waiting for the approval, I guess she filed some kind of paperwork for exemption? Not sure what they're doing but it seems to take time and the next assignment is supposed to start Wednesday so pretty much no chance.
In my other job, we are technically supposed to be vaxxed but I know a lot of people who are not and HR is not really enforcing us to send the proof of vax status.
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Hello all.
I am imploring everyone I can find to take their shots. I have a YouTube video to post, but I don't have 50 posts yet.
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[QUOTE=Stevencjackson;1649496773]Hello all.
I am imploring everyone I can find to take their shots. I have a YouTube video to post, but I don't have 50 posts yet.[/QUOTE]
I'm headed to the rope store you want something?
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[QUOTE=Stevencjackson;1649496773]Hello all.
I am imploring everyone I can find to take their shots. I have a YouTube video to post, but I don't have 50 posts yet.[/QUOTE]
well snap to it, man! Those 49 posts aren't gonna write themselves!
Why not start by sharing something aboot yourself. First kiss, favorite band, hobbies... :)
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[QUOTE=Stevencjackson;1649496773]Hello all.
I am imploring everyone I can find to take their shots. I have a YouTube video to post, but I don't have 50 posts yet.[/QUOTE]
Jack son, post it without the http. Maybe it’ll work if people copy paste it but it better be worth our time or negs make you a bright red
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[img]https://i.imgur.com/oqaAqbl.jpg?1[/img]
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[QUOTE=ChazWood;1649503753]...Why not start by sharing something aboot yourself....[/QUOTE]
How about he mentions sport, maybe bodybuilding powerlifting Olympics lifting general weights, something about training.
Sometimes I feel like we don't get enough bodybuilding posts on this Covid discussion forum website
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[img]https://i.imgur.com/EsFwTou.jpg?1[/img]
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[QUOTE=mtpockets;1649537183][img]https://i.imgur.com/EsFwTou.jpg?1[/img][/QUOTE]I had a surfboard manufacturing business for 40 years and I used the N95 mask and after taking it off my nostrils would be full of dust so how people think this thing would stop particles probably a million times smaller is beyond me
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I personally know 12 people who are vaccinated and have gotten Covid now.
Jfl at lab monkey vaxxers
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[QUOTE=MuscleXtreme;1649539703]I personally know 12 people who are vaccinated and have gotten Covid now.
Jfl at lab monkey vaxxers[/QUOTE]
Interesting.
How many of of them got severely sick? Like sick like a dog?
I’m assuming nothing majorly unfortunate happened to them else you would’ve said something. Or no?
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[QUOTE=Tommy W.;1649537433]I had a surfboard manufacturing business for 40 years and I used the N95 mask and after taking it off my nostrils would be full of dust so how people think this thing would stop particles probably a million times smaller is beyond me[/QUOTE]
The virus is carried in the moisture exhaled from the lungs of infected persons. No? It’s not directly flying out of the lung and into the air. Or is it?
Srs question
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The majority of the people in my zone are vaccinated and the majority of cases are in the unvaccinated, seeing some cases in the vaccinated but that is to be expected since the vast majority is vaxxed.
Considering the Delta variant was the worse so far and given the rapid decline in cases, It obvious that the vax has slowed the spread.
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[QUOTE=TryingBB;1649540523]Interesting.
How many of of them got severely sick? Like sick like a dog?
I’m assuming nothing majorly unfortunate happened to them else you would’ve said something. Or no?[/QUOTE]
Such dumb logic that is completely unprovable, which is why I dub people like you dishonest.
Your claim: See they didn’t go to the hospital so it shows that the shot works.
Perhaps those people would have never gone to the hospital if they didn’t have the shot as well.
Also, I know plenty of people that had gotten Covid pre-Covid shot release and guess what. They didn’t go to the hospital either.
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[QUOTE=mtpockets;1649540893]The majority of the people in my zone are vaccinated and the majority of cases are in the unvaccinated, seeing some cases in the vaccinated but that is to be expected since the vast majority is vaxxed.
Considering the Delta variant was the worse so far and given the rapid decline in cases, It obvious that the vax has slowed the spread.[/QUOTE]
You don’t even know if you had delta unless you got it genetically sequenced. They aren’t doing those on individuals.
Jfl at the brainwashing.
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[QUOTE=MuscleXtreme;1649541393]You don’t even know if you had delta unless you got it genetically sequenced. They aren’t doing those on individuals.
Jfl at the brainwashing.[/QUOTE]
Duh.... just about everyone knows this dumbass... That's how it's identified
We got a live one here folks....
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[QUOTE=mtpockets;1649541813]Duh.... just about everyone knows this dumbass... That's how it's identified
We got a live one here folks....[/QUOTE]
Point being that the vast vast majority of people can’t say they got delta, because they simply don’t know.
But knuckleheads like yourself just eat it up and create repeating Delta, Delta, Delta!
Jfl
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[QUOTE=TryingBB;1649540633]The virus is carried in the moisture exhaled from the lungs of infected persons. No? It’s not directly flying out of the lung and into the air. Or is it?
Srs question[/QUOTE]
If that's a serious question, the serious answer is that the virus is carried on droplets. Some relatively large that are easily caught by a mask and some that are tiny aerosol that are not.
That's why masks (used correctly) reduce transmission (because they stop a high proportion of droplets) but not all droplets which is why that proportion isn't 100%
But the size of the virus itself is largely irrelevant
Please can we stop talking about Delta, that's so last season. The cool kids are all talking about Delta2. (d.2 / AY4.2) follow the fashion, that's the one to get this week.
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[QUOTE=MuscleXtreme;1649541973]Point being that the vast vast majority of people can’t say they got delta, because they simply don’t know.
But knuckleheads like yourself just eat it up and create repeating Delta, Delta, Delta!
Jfl[/QUOTE]
Listen here douchebag, I don't recall saying anyone said they had Delta, I said "Considering the Delta variant was the worse so far" If you are trying to impress me with your wealth of knowledge you are failing miserably. Even a 12 year old can google the nonsense you are spilling out. So you just keep throwing out garbage and trying to belittle people, it truly is testimony to your lack of knowledge and character. You are just another troll, so with all due respect, go fuk yourself. I won't be engaging with you because you obviously can't carry on a discussion in a civil manner.
Bye Felicia
Jfl at the troll living in mommies basement.
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[QUOTE=mtpockets;1649542583]Listen here douchebag, I don't recall saying anyone said they had Delta, I said "Considering the Delta variant was the worse so far" If you are trying to impress me with your wealth of knowledge you are failing miserably. Even a 12 year old can google the nonsense you are spilling out. So you just keep throwing out garbage and trying to belittle people, it truly is testimony to your lack of knowledge and character. You are just another troll, so with all due respect, go fuk yourself. I won't be engaging with you because you obviously can't carry on a discussion in a civil manner.
Bye Felicia
Jfl at the troll living in mommies basement.[/QUOTE]
Lol unhinged.
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[QUOTE=MuscleXtreme;1649544543]Lol unhinged.[/QUOTE]
Would u not agree that hinged objects often limit movement to 1 rotational axis? Not always optimal, unless you're a door.
Mabe something to think aboot next time you're trying to insult someone. :D
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Wife getting her booster today. Hope she lives.
[QUOTE=MuscleXtreme;1649541393]You don’t even know if you had delta unless you got it genetically sequenced. They aren’t doing those on individuals.
[B]Jfl at the brainwashing.[/b][/QUOTE]
What irony
