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[QUOTE=DustinTheHuss;1637966023]It's very different from working shoulders in the gym. It's hard to describe, but it just even hurt to have my arm resting on me on the couch. I wasn't even laying on it.[/QUOTE]
I was told to do OHP movement without any weights and massage the area. Take Tylenol.
I didn’t need Tylenol just did OHP movements and did gentle warmups. Felt better as some blood flowed through the area I think.
It’ll start getting better soon hopefully
[QUOTE=JustTheDad;1637956023]... Medical Director at a CRO....[/QUOTE]
Someone who actually knows what they are talking about...??? in Misc????? that's not right
[i]MODS!!! ban him please[/i]
;)
[QUOTE=eomrat;1637952553]Ok, Brother. I am about to make it worse. That gun did not have needles. Note the two air lines running to the gun. That "gun" used 1200 PSI delivered through tiny nozzles to literally shoot three liquids into your arm.
I shyt you not.
"One is that the shots required patients to stay still as the end of the gun was applied and the trigger was pulled. The vaccine came out at 1,200 psi and if a person flinched — and the nozzle wasn’t butted up straight against the arm — the powerful stream of liquid could tear the skin"
[url]https://www.washingtonpost.com/local/jet-injectors/2021/02/02/23f3b8b0-6578-11eb-886d-5264d4ceb46d_story.html[/url]
[url]https://jetinfectors.com/category/military-jet-injections/[/url][/QUOTE]
Damn Brother... I did not know that, I never did research it and I never look when getting needles. It wasn't a pleasant experience and i had the scar for ever. Thanks for posting that, I would have never known.
[QUOTE=JustTheDad;1637956023]
I'm not directly assigned to any of our vaccine trials right now but some of the docs that "report" to me are. A lot of people on the vaccine studies are working weekends or having to review listings at 2am to avoid delays. Despite that, nobody is complaining. Everyone just says that they can't go anywhere anyway, so they might as work over the weekend.[/QUOTE]
Are these studies gathering additional data on the current vaccine technologies or are there new ones on the horizon too (if you can say)?
[QUOTE=eomrat;1637952553]
"One is that the shots required patients to stay still as the end of the gun was applied and the trigger was pulled. The vaccine came out at 1,200 psi and if a person flinched — and the nozzle wasn’t butted up straight against the arm — the powerful stream of liquid could tear the skin"
[/QUOTE]
Got the gun in '66 at Benning. Some flinched, some did not. The above is true.
[QUOTE=JustTheDad;1637956023]Thanks. And yes. That day job I mentioned in an earlier post is working as a Medical Director at a CRO.
I'm not directly assigned to any of our vaccine trials right now but some of the docs that "report" to me are. A lot of people on the vaccine studies are working weekends or having to review listings at 2am to avoid delays. Despite that, nobody is complaining. Everyone just says that they can't go anywhere anyway, so they might as work over the weekend.
We can't rush the data collection, but we've sized the studies so they can show safety and efficacy in a very short period of time, so anything the medical monitors can do to avoid delays is being done. The same is true for clinical, data management, safety, regulatory, and every other group involved from the study sites all the way to the statisticians. The entire industry knows that if the data is going to show another vaccine is safe and effective, getting that data cleaned and analyzed just one week faster means production ramps up a week earlier, and that could save a lot of lives. It's impressive.
[B]You know, with all silliness about the vaccines having weird side effects, when I was getting my shot, I was thinking it would be really cool if my Pfizer vaccine could give me super powers or maybe heal my rotator cuff injury as an unexpected side effect. Instead it just gave me a completely expected sore deltoid and some protection from the virus. [/B]
I know that sounds silly, but I mention it to show that someone like me, who knew exactly what was in it, how it was tested and what the data showed, was so unconcerned about side effects when they stuck the needle in my arm that I was entertaining myself with X-Men scenarios instead of worrying about an adverse reaction.[/QUOTE]
I am one shot in on Pfizer and penis is already about 30% larger. Am I the only one?
[QUOTE=mgftp;1637974733]I am one shot in on Pfizer and penis is already about 30% larger. Am I the only one?[/QUOTE]
I got both Pfizer shots....... Heading to the can
to check it out.
[QUOTE=mgftp;1637974733]I am one shot in on Pfizer and penis is already about 30% larger. Am I the only one?[/QUOTE]
LMAO, I will definitely be looking for Pfizer
[QUOTE=ljimd;1637974983]I got both Pfizer shots....... Heading to the can to check it out[/QUOTE]
Ha Ha, careful, it's all fun and games until someone loses an eye.
[b] Just got a text from Tater, all went well[/b]
[img]https://i.imgur.com/wyqjks4.png?1[/img]
.
[QUOTE=ljimd;1637974633]Got the gun in '66 at Benning. Some flinched, some did not. The above is true.[/QUOTE]
'66 was a hell of time to pass through Ft Benning
[QUOTE=eomrat;1637977843]66' was a hell of time to pass through a Ft Benning[/QUOTE]
"Sand Hill" B-10-3 - a lifetime ago.
[QUOTE=ljimd;1637974633]Got the gun in '66 at Benning. Some flinched, some did not. The above is true.[/QUOTE]
Howdy Brother....
In my case...they used the gun in '65 too. (MCRD San Diego)
Correct me if I'm wrong but I seem to recall some issue during that era, or a bit later, that they were having some problems with gun process?
Can't recall exactly if there were some infections as a result of gun injections or something else.....I'm old too. :)
Since yesterday's vaccine....no negative reactions other than the injection region itself being a bit sore.
Nothing more for us.
Have a great weekend everyone....
[QUOTE=mgftp;1637974733]I am one shot in on Pfizer and penis is already about 30% larger. Am I the only one?[/QUOTE]
Don't worry, it shrinks by 40% after the second shot.
[QUOTE=Wayne Evans;1637978873]Howdy Brother....
In my case...they used the gun in '65 too. (MCRD San Diego)
Correct me if I'm wrong but I seem to recall some issue during that era, or a bit later, that they were having some problems with gun process?
Can't recall exactly if there were some infections as a result of gun injections or something else.....I'm old too. :)
Since yesterday's vaccine....no negative reactions other than the injection region itself being a bit sore.
Nothing more for us.
Have a great weekend everyone....[/QUOTE]
Since there are no needles, the gun supposedly did not need sanitizing between injections. However, that shyt theory failed to account for the flinchers. Flinching leads to a good bit of bleeding and the gun is placed directly against the skin. You and your boys may have been Blood Brothers way before you got to RVN.
[QUOTE=eomrat;1637983873]Since there are no needles, the gun supposedly did not need sanitizing between injections. However, that shyt theory failed to account for the flinchers. Flinching leads to a good bit of bleeding and the gun is placed directly against the skin. [B]You and your boys may have been Blood Brothers way before you got to RVN[/B].[/QUOTE]
Brother Doug....
Ha...no shvt...I never thought about that.
In fact, until you gents qualified it, [I]I never knew[/I] that there were actually no needles involved with the gun and it was pressure only.
Hope all is well with you.
Carry on....
[QUOTE=ajdahlheimer;1637906553]Just got the second shot today. Came to the site directly from lifting..... :-)[/QUOTE]
Had some chills, bad body/muscle aches, and was warm this morning. Then all of the sudden I broke a profuse sweat and now feel completely fine. Very odd.
[QUOTE=ChazWood;1637960513]So which X-man would you be?
![/QUOTE]
Wolverine. That healing factor seems is appealing as does the longevity.
[QUOTE=mgftp;1637974733]I am one shot in on Pfizer and penis is already about 30% larger. Am I the only one?[/QUOTE]
The sites only are only required to report adverse events and adverse drug reactions. I don’t think that would qualify.
[QUOTE=OldFartTom;1637970513]
[i]MODS!!! ban him please[/i]
;)[/QUOTE]
Ouch (lol)
[QUOTE=ectoBgone;1637974373]Are these studies gathering additional data on the current vaccine technologies or are there new ones on the horizon too (if you can say)?[/QUOTE]
Not sure what you’re asking since you said vaccine technologies. The idea of using mRNA isn’t that new, but the designs of the capsules around each vaccine, the coating which lets us sneak the mRNA into your cells, are different or new. I think sputnik’s use of two different vectors for the first and second shot is brilliant, but I don’t know if it’s new.
As far as what we’re studying. There are a lot of covid vaccines being tested and actually a lot of other vaccines being tested too. So we’re gathering data on new covid vaccines that are hoping to get approved and yes, we are also collecting more data on the vaccines that already got EUA. Pfizer is asking for full approval now. I’m sure Moderna will soon too. CureVac and NovaVax have big studies going that are close to being able to submit for EUA if they haven’t already, and I’m not sure who else does. WallStreet is following that pretty closely so Google can tell you.
EUA requires 2 months of safety data after the shot and full approval requires 6. I don’t know if it’s 6 months on all the subjects or just enough to rule out certain statistical signals. Our follow up doesn’t actually end at 6 months though. We will keep following those patients for 1 to 2 years based on the individual protocols which each sponsor works out with the regulatory authorities. That follow up isn’t perfect though. Two years of follow up sounds good, but it’s going to be very difficult to interpret because unlike most blinded trials we run where the subjects are either on placebo or the IP for the duration of the study, in this case, if they can get a vaccine outside the study, the subjects will. So people on a Pfizer study may be getting a J&J shot or Moderna shots or any of the others when their name comes up. At that point their data becomes less useful. It’s also why conducting trials on new vaccines is going to get more and more difficult. We clearly can’t run them in Israel, and even the US is becoming difficult in some age groups. Is there anyone over the age of 65 in the US that would be willing to get an investigational product vaccine and hasn’t already gotten an EUA vaccine? So it gets difficult to find unvaccinated subjects, which is obviously good from a public health perspective, but bad if we want to study new vaccines.
I don’t know if the studies unblind subjects when asked to, to avoid anyone getting multiple vaccines. I’ll ask our vaccine expert later today. He’s a VERY popular guy these days and I'm sure a bunch of other CRO’s are currently trying to steal him.
Gotta get some work done now so apologies if I have typos or such in this or it's unclear.
[QUOTE=Wayne Evans;1637984473]
In fact, until you gents qualified it, [I]I never knew[/I] that there were actually no needles involved with the gun and it was pressure only.
Carry on....[/QUOTE]
Me either Wayne, I still have the scar and it was 45 years ago
[QUOTE=ajdahlheimer;1637984633]Had some chills, bad body/muscle aches, and was warm this morning. Then all of the sudden I broke a profuse sweat and now feel completely fine. Very odd.[/QUOTE]
Thanks for the update, sounds like you are through it now
They wouldn’t give me my shot cause of the tet shot, they don’t want anything to interfere with this not working.
I’m scheduled at the end of month.
They almost scheduled my second shot 2weeks after my first, I say, I thought I gotta wait 4 weeks???????
,...,...man, you gotta watch ‘em.
[QUOTE=LWW;1637985563]They wouldn’t give me my shot cause of the tet shot, they don’t want anything to interfere with this not working.
I’m scheduled at the end of month.
They almost scheduled my second shot 2weeks after my first, I say, I thought I gotta wait 4 weeks???????
,...,...man, you gotta watch ‘em.[/QUOTE]
Sounds like you have to watch them.
Why didn't your doc tell you this yesterday?
Did your missus get hers?
[QUOTE=mtpockets;1637985183]Me either Wayne, I still have the scar and it was 45 years ago. [/QUOTE]
Brother MTP....
Ha....at least I'm not the only one.
What I do recall though is a shvt load of contact with that gun prior to embarking on a long picnic.
Hope all is well.
[QUOTE=mtpockets;1637986073]Sounds like you have to watch them.
Why didn't your doc tell you this yesterday?
Did your missus get hers?[/QUOTE]
All the doc did was ask me questions (I was a new patient) then his nurse asked me questions and gave me a tet along with telling to go down to the lab and draw blood.
I told the doc no to the Covid, but my wife told him yes so he scheduled us both. The nurse never asked about Covid.
But it really don’t matter cause I was overdue for the tet and they weren’t going to give me both, I haven’t seen a doc in over 20 years this was all wife’s doing.
Btw I had shorts on, doc goes what’s up with those scabs and bruises on your shins, told him that from lifting weights, he says, exercise? I say yeah, he says you definitely need a tet shot then!
[QUOTE=LWW;1637986593]All the doc did was ask me questions (I was a new patient) then his nurse asked me questions and gave me a tet along with telling to go down to the lab and draw blood.
I told the doc no to the Covid, but my wife told him yes so he scheduled us both. The nurse never asked about Covid.
But it really don’t matter cause I was overdue for the tet and they weren’t going to give me both, I haven’t seen a doc in over 20 years this was all wife’s doing.
Btw I had shorts on, doc goes what’s up with those scabs and bruises on your shins, told him that from lifting weights, he says, exercise? I say yeah, he says you definitely need a tet shot then![/QUOTE]
Yeah, the tetanus is something you should keep up on, my old man stepped on a nail, got lock jaw and almost died. After seeing what he went through, I keep mine up to date, well I try anyway lol
I am not big on doctor visits either.. Good stuff on the Jab.
[QUOTE=mtpockets;1637986853]Yeah, the tetanus is something you should keep up on, my old man stepped on a nail, got lock jaw and almost died. After seeing what he went through, I keep mine up to date, well I try anyway lol
I am not big on doctor visits either.. Good stuff on the Jab.[/QUOTE]
Damn, I was actually wondering if anyone actually has stepped on a nail and gotten that chit.
Oh and wife got hers, I’ll get mine later, no biggie.
The side effects I got from the tet seem the same as Covid as I’m reading really, last night I only felt bad when resting, I got up, did some chores and was fine within an hour. I’m sure the same happened 15- 20 years ago too, but at that age I ignored it, lol.
[QUOTE=LWW;1637987463]Damn, I was actually wondering if anyone actually has stepped on a nail and gotten that chit.
Oh and wife got hers, I’ll get mine later, no biggie.
The side effects I got from the tet seem the same as Covid as I’m reading really, last night I only felt bad when resting, I got up, did some chores and was fine within an hour. I’m sure the same happened 15- 20 years ago too, but at that age I ignored it, lol.[/QUOTE]
I have heard that the tetanus shot hits some people hard, other than a bit sore at the injection site, I don't recall having side effects. Good stuff on yer missus getting the jab.
[QUOTE=Cass40;1637947523]Ok you're being weird again. There's no way the doctor is giving you a tetanus vaccine and covid vaccine the next day.[/QUOTE]
[QUOTE=LWW;1637985563]They wouldn’t give me my shot cause of the tet shot, they don’t want anything to interfere with this not working.
I’m scheduled at the end of month.
They almost scheduled my second shot 2weeks after my first, I say, I thought I gotta wait 4 weeks???????
,...,...man, you gotta watch ‘em.[/QUOTE]
Nobody ever listens to me :rolleyes:
[QUOTE=LWW;1637987463]Damn, I was actually wondering if anyone actually has stepped on a nail and gotten that chit.
Oh and wife got hers, I’ll get mine later, no biggie.
The side effects I got from the tet seem the same as Covid as I’m reading really, last night I only felt bad when resting, I got up, did some chores and was fine within an hour. I’m sure the same happened 15- 20 years ago too, but at that age I ignored it, lol.[/QUOTE]
I keep current on tetanus always. I've had nail-stepping experiences and plenty of other reasons to stay on top of it. One of my best friends growing up almost died of lockjaw when he didn't have the shot and had a cut from rusty corregated iron. Scary.
[QUOTE=LWW;1637986593]All the doc did was ask me questions (I was a new patient) then his nurse asked me questions and gave me a tet along with telling to go down to the lab and draw blood.
I told the doc no to the Covid, but my wife told him yes so he scheduled us both. The nurse never asked about Covid.
But it really don’t matter cause I was overdue for the tet and they weren’t going to give me both, I haven’t seen a doc in over 20 years this was all wife’s doing.
Btw I had shorts on, doc goes what’s up with those scabs and bruises on your shins, told him that from lifting weights, he says, exercise? I say yeah, he says you definitely need a tet shot then![/QUOTE]
Good for you LWW. Glad you're getting it.
[QUOTE=Cass40;1637989633]Nobody ever listens to me :rolleyes:[/QUOTE]
We always listen to you. :P
[QUOTE=Cass40;1637989633]Nobody ever listens to me :rolleyes:[/QUOTE]
I did, I told them the minute I got there, but I never even thought about it until you said it.
Even still they give you a paper to fill out before getting the vaccine asking that very question.
I suppose if the doc did everything on his own, he woulda caught this before me coming in there. But he has nurses and recesponists juggling all the info at once.
[img]https://i.imgur.com/H7OwpsZ.png?1[/img]
[QUOTE=mgftp;1637974733]I am one shot in on Pfizer and penis is already about 30% larger. Am I the only one?[/QUOTE]
Damn you shrank and your penor stayed the same size? Maybe everything shrank and the penor is erect 100% of the time?
A little follow up. None of us knew for sure when I asked, but it seems most likely that the requirement for EUA are that the average follow up be at least 2 months, and for full authorization, that it is at least 6 months when you apply. Regulatory isn't what we've been focusing on, sorry.
During the call, someone pointed out that we as doctors are doing a terrible job in explaining that these studies weren't rushed. It's simply that to gather the data for a vaccine study, we'd normally spend several years just trying to enroll the subjects. Since these studies enrolled 30 or 35 or 40,000 subjects in weeks instead of years, we were able to collect as much or more data on the COVID vaccines in a few months, than we normally collect in years on other vaccine trials.
I also learned that all the studies any of our group is aware of, do unblind a person if they're going to get a vaccine outside the trial. They also unbinded at least one after a few months and let people who had received placebo cross over to the active study arm. The incidence of the virus is high enough that they could collect enough efficacy data very quickly, do that crossover, vaccinate all the study subjects, and then collect safety data on even more people.