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cakedonkey
04-12-2006, 12:58 AM
S.A.N. Blaze Xtreme :: Lipotropic Inferno :: Information/FAQ

Product Information
<img src="http://fredvaughn.org/san/blazextreme-facts.jpg" alt="S.A.N. Blaze Xtreme">

Blaze Xtreme in the Cyberstore
[not yet available]

Formula rationale

Delta Force Mission: Set Fat Free… Then Destroy It!

Delta 5-E
Delta 5-E (the trademark name for SAN’s exclusive 7-Keto-DHEA Ester technology) is a metabolite of DHEA that has an uncoupling effect inside the mitochondria of fat cells (2), so it allows for fat to be easily and readily released from its cell compartment and thus utilized as the preferred source of energy.

Delta 5-E also increases natural thyroid gland production by stimulating the release of the thyroid hormone T3 and the important conversion of T4 to T3 (1) to easily access and destroy fat during exercise. (see graph A) Delta 5-E also coaxes the synthesis of cortisol (3), so it short circuits cortisol’s attempt to obscure 6-packs of ripped abs while keeping the immune system strong.

Beyond Ephedra… Way Beyond!™

Tyramine
Tyramine makes dieting effortless. Ephedrine worked well for fat burning because it stimulated the neurotransmitter, norepinephrine (NE). The problem is that NE must remain free to circulate in the body to be effective. Tyramine remedies this problem by fitting inside the NE receptor. It takes the “parking space” usually reserved only for NE, so it remains active and torches all the body fat in its path.

Ephedra was never able to take NE’s parking space (see graph B) so Tyramine is more effective, much safer and completely legal. Tyramine also supports mood elevation, even during normally trying diets.

Burn Fat & Gain Muscle Simultaneously

Forskolin
Forskolin has been used for over 1000 years, but a recent study proved body fat decreased significantly with a dose of just 500mg of Coleus Forskohlii (10% Forskolin) per day. More amazingly, not only did muscle mass not decline… it actually increased as the fat loss was taking place! The seeming impossibility of burning fat and gaining muscle simultaneously is finally a reality… and now available to you in BLAZE Xtreme.

Forskolin also increases the overall metabolic rate by stimulating the secretion of T4 from the thyroid and promoting the T4/T3 conversion and may actually supports growth hormone (GH) production (15), which further enhances its fat burning effects.

Forskolin forces body fat to be burned as fuel by activating an enzyme in the fat cell called Hormone Sensitive Lipase (HSL) to release fat to travel where it’s needed as fuel… primarily to working muscles.

Typically the body requires hormones like epinephrine and NE to bind to fat cell receptors in order to activate HSL. Forskolin overcomes the problem of epinephrine and NE deactivation by mimicking the effects of these fat mobilizing hormones, but bypassing the beta-receptors that normally bind them. Forskolin is able to enter fat cells through the membrane, which increases the levels of Cyclic Adenosine MonoPhosphate (cAMP). The increase in cAMP activates more HSL, which frees up more TG - Triglycerides (fat) to be used as fuel. (see graph C)

Forskolin also increases T3 levels in muscle tissue, which potentiates the “citric acid cycle” (krebs cycle). This forces the fat stored in muscle to be burned without the production of ATP. Normally, ATP must be present as part of the krebs cycle. But Forskolin activates the krebs cycle without ATP, and in the process forces stored fat to be transported to the muscles to be burned as fuel.

Fat Burning Amplification!

Green Tea Extract (EGCG)
Green Tea stimulates fat loss in numerous ways, but because of its caffeine content it works perfectly with Forskolin to prolong the action of cAMP, while amplifying and intensifying the actions of HSL… and you need high levels of cAMP to activate HSL.

Norepinephrine (NE) binds to receptors on the surface of fat cells to stimulate the activity of HSL so fat is used as fuel. Unfortunately- under normal conditions- NE is broken down by an enzyme called catechol O-methyltransferase (COMT). This is where green tea comes to the rescue. The catechins (specifically EGCG) in green tea inhibits COMT (5), which prolongs the life and effectiveness of NE. (see graph D)

Green tea is also great for dieting because it’s a natural appetite suppressant that increases both NE and dopamine (7). Tea polyphenols can elevate cholecystokinin (CCK), a hormone that suppresses food intake. So green tea simultaneously causes appetite suppression and decreased digestibility of fat.

Appetite Suppression & Fat Loss

Caffeine
Caffeine is included in BLAZE Xtreme to potentiate the effects of compounds like Tyramine and Forskolin (9). Plus caffeine helps with short-term appetite suppression and fat loss.

Increased Metabolic Activity

Bacopa Moniera (Bacosides A & B)
Bacopa monniera has been used in the Ayurvedic (Hindu) system of medicine for centuries but in a recent study Bacopa extract increased levels of T4 by 41% which means increased metabolic activity for even more dramatic fat loss results. (16)

Break Down And Exterminate Fat!

TTA (Tetradecylthioacetic Acid)
TTA stimulates the breakdown of triglycerides (fat) by signaling the liver to catabolize fatty acids, causing the rapid clearance of fat from the blood stream (11). TTA also completely abolishes diet induced insulin resistance and thus improves insulin sensitivity (12).

Now have the knowledge and the power. So, don’t just hope your fat burner works. Demand the one that’s scientifically engineered to burn fat faster, more completely and effectively than any other fat burner in the world. BLAZE Xtreme is the answer. The question is… what are you waiting for?*


<img src="http://www.sann.net/images/blazextreme-graphs.gif" alt="How Blaze Works">

References cited: Clin Chem Lab Med. 2003 Aug; 41(8): 1081-6.
Arch Biochem Biophys. 1997 May 1; 341(1): 122-8.
Arch Biochem Biophys. 2003 Apr 15; 412(2): 251-8.
Int Rev Neurobiol. 2001; 46:79-95.
Chantre P, Lairon D, 2002
Dulloo AG, Duret C, Rohrer D, Girardier, 1999
Yokogoshi H, Kobayashi M, Mochizuki M, 2002
Liao S, 2001
Crit Rev Food Sci Nutr. 2005; 45(7): 535-62
Curr Opin Lipidol. 2002 Jun; 13(3): 295-304.
Biochimie. 2005 Jan; 87(1): 15-20
J Lipid Res. 2002 May; 43(5): 742-50
Obes Res. 2005 Aug; 13(8): 1335-43
J Clin Invest. 2001 Sep; 108(5): 733-7
Braz J Med Biol Res. 1994 May; 27(5): 1269-72.
J Ethnopharmcol. 2002 Jul; 81(2): 281-5
J Ethnopharmcol. 1982 Mar; 5(2): 205-14
Sabinsa Research, 2004
[adapted from: http://www.sann.net/blazextreme.html]




Blaze Xtreme Reviews


[pending] (#)

Blaze Xtreme Freqently Asked Questions
Q: What sets this apart from the original Blaze? To say the least: a lot. The original Blaze formula contained only our Delta-5-E. We've really kicked things up, however, with the reformulated product. As you can clearly see from the write-up, every single active is scientifically supported to attack fat-loss from every possible angle. Would you expect any less from S.A.N.?

Q: If I'm already using green tea extract, should I continue its use alongside Blaze Xtreme? Definitely! Blaze Xtreme contains a decent amount of EGCG, but it couldn't possibly hurt to get more. Green tea should be used year-round for fat-loss benefits and general health benefits alike.

Q: Could I use Tight! along with Blaze Xtreme? No. Tyramine works through a similar pathway as ephedra, and these two are not recommended together under any circumstances.

Q: Should Blaze Xtreme be cycled? After you're finished using the product, it wouldn't be a bad idea to take a week or two off before considering another run.

Q: Could I use Sesamin along with this product? Yes. The two products together will compliment the actions of one another very well.

Q: What about ephedra? Would that be smart to use alongside Blaze Xtreme? No--this is dangerous. As Chris puts it:
Combining tyramine and ephedrine is a bad idea. Tyramine is a competitive NE re-uptake inhibitor, and ephedrine/caffeine exerts at least 50% of its effects via central catecholamine (primarily NE) release from sympathetic nerve terminals. Short version is the two together is not advisable, and not just for liability reasons.

jaymode
04-12-2006, 07:42 AM
looks pretty good by ingredient profile. Might have to try it out sometime.

Coulaid
04-12-2006, 07:45 AM
There putting you to work early cake :D Nice FAQ's:D

cakedonkey
04-12-2006, 12:30 PM
Thanks jay, Coulaid!

Anyone have any questions on the formula?

TimoteoS
04-12-2006, 12:53 PM
i hate to say this but imo i think it may be a little underdosed but im not here to cause any trouble...though you never know the dose's your getting with a proprietary blend this could turn out to be a very strong and great product with alot of ingredients that should have a nice synergy together......but imo if I was to come out with a product with these ingredients I would have-

TTA-250-1000 mg daily
Green Tea-300-500 mg at 50% ECGC daily
Caffeine-75-200 mg dose
Forskolin -100 mg at 20% for an adequate dose
Bacoba Monniera- 125-375 mg at 50% Bacosides A & B in humans for an adequate dose
Tyramine-50 mg dose

anyways...this seems similar to the product omega is coming out, this just has more ingredients....i plan on using san attitude soon and watching what happens with this product

cakedonkey
04-12-2006, 05:01 PM
Yes, the syergistic effects of such a blend of compounds cannot be overstated. It's very well-rounded.

The problem with your proposed formulation is how much that would jack up costs. The Blaze Xtreme formula has just enough of everything to provide the benefits of each compound. Sometimes, you don't need an all-out full dosage of something, given its effectiveness at a lower dosage and/or synergy, as aforementioned.

Users can also run green tea alongside Blaze Xtreme which is dirt-cheap, as is caffeine. Forskolin definitely isn't the cheapest thing around, however.

I think the Delta 5-E will also have a lot to do with the excellent results users will see (original Blaze reviews were very positive).

Togoro
04-12-2006, 05:58 PM
Looks like a pretty interesting product.


I'm looking forward to testing it out.


I know Lonny mentioned it should be ready soon, any better idea yet?

daveburton
04-14-2006, 01:10 AM
Thanks jay, Coulaid!

Anyone have any questions on the formula?

Wouln't you also avoid taking Y with Tyramine? At least this is what I understand from the literature since it stimulates NE release just like E does?

cakedonkey
04-14-2006, 11:16 AM
Yes, I believe you are right on that.

Togoro
04-14-2006, 11:16 AM
Bump

daveburton
04-15-2006, 12:32 AM
Yes, I believe you are right on that.


Well, then this probably needs updating???

Q: Could I use Sesamin along with this product? As with Tight!, it would be an excellent addition. Blaze + Tight! + Sesamin would make for an amazingly potent and synergisitc combination. In fact, there is practically not one aspect missing in terms of attacking fat loss with this stack. As with all S.A.N. products, results are promised.

Remember, Tight contains Y!!!!

cakedonkey
04-15-2006, 12:41 AM
Problem is, it's been too long and now the "Edit" button doesn't work on the original post.


What I will hope, however, is that when users read this thread to check out the FAQ they read the entire thread...

BringnIt
04-15-2006, 01:16 AM
PM a mod.

cakedonkey
04-15-2006, 01:24 AM
PM a mod.


Good call. And thanks for pointing that out Dave, something I definitely overlooked at the time.

daveburton
04-15-2006, 10:08 PM
you are welcome

cakedonkey
04-16-2006, 09:00 AM
FAQ has been fixed. Much thanks to Bignbuff.

sjl25
04-16-2006, 09:24 AM
It looks promising for sure. I have been using Forslean for a few weeks with good results.

The one thing that I'll never understand is why everyone seems to throw caffeine into their products. Just because it is cheap and effective does not warrant its inclusion in every fat-loss/ thermogenic product. There are some potentially good thermogenic stacks out there that are not realistically feasible due to the combined caffeine content.

daveburton
04-16-2006, 08:51 PM
There are some potentially good thermogenic stacks out there that are not realistically feasible due to the combined caffeine content.

You are absolutely right. But keep in mind that it is not in any companies interest to design products that need (or can) to be stacked with competing products. With that said, caffeine is (and rightfully should be) a main stable in any good fat burner these days as it potentiates the effects of adrenergic substrates such as synephrine, yohimbine, tyramine etc

Lonny
04-17-2006, 06:34 AM
It looks promising for sure. I have been using Forslean for a few weeks with good results.

The one thing that I'll never understand is why everyone seems to throw caffeine into their products. Just because it is cheap and effective does not warrant its inclusion in every fat-loss/ thermogenic product. There are some potentially good thermogenic stacks out there that are not realistically feasible due to the combined caffeine content.


As dave mentioned, caffeine is included a lot of the time for the potentiation of things it is combined with. And it is the basis for a stimulant fat burner, otherwise you aren't talking a stimulant.

naturalguy
04-17-2006, 06:47 AM
Just an FYI, if you compete in the INBF you would not be able to take this product as it would be considered a banned substance (7 Keto and DHEA are banned)

sawastea
04-17-2006, 06:56 AM
Just an FYI, if you compete in the INBF you would not be able to take this product as it would be considered a banned substance (7 Keto and DHEA are banned)

7-Keto is banned?!? :eek:

naturalguy
04-17-2006, 07:09 AM
7-Keto is banned?!? :eek:

Yup, unfortunately a lot of things are. This is directly from their website:

HORMONES AND ALL PRECURSORS & METABOLITES, DERIVATIVES AND RELATED COMPOUNDS The use of any hormone (injectable, oral, sublingual or otherwise) for bodybuilding purposes including insulin is strictly prohibited. All hormonal precursors (DHEA, androstenedione, 19-norandrostenedione, androstenediol, 5-AD, 7-KetoDHEA, androsteneTRIONE, etc.) are banned effective January 1, 2000. Prescription Thyroid hormone medication when used for bodybuilding purposes is banned. Pro-Steroids (1-Test), etc. are banned effective January 1, 2000. The presence of any banned substance in the urine (i.e., nandrolone, etc.), no matter how it arrived there, is ruled as a positive (failure).

Their complete banned list can be found here:

http://www.inbf.net/drugfree.html

TimoteoS
04-17-2006, 07:48 AM
http://www.bodybuilding.com/store/7keto.html

sorry but all those products still sell 7 keto dhea...

naturalguy
04-17-2006, 08:27 AM
http://www.bodybuilding.com/store/7keto.html

sorry but all those products still sell 7 keto dhea...

It's only banned by the INBF, so if you compete in that organization then you can't take products that have 7Keto

TimoteoS
04-17-2006, 08:31 AM
It's only banned by the INBF, so if you compete in that organization then you can't take products that have 7Keto
o sorry man, i misunderstood you...my fault

KennyK
05-09-2006, 11:04 AM
Is this product comparable to ephedra, meaning an someone sensitive to stimulants take it. That's why I liked blaze, because it was excellent for people who are sensitive to stimulants.

Also, can you drink coffee along with this?

KennyK
05-09-2006, 11:37 AM
bump

cuponoodles
05-09-2006, 12:59 PM
So you get 15 days worth from a bottle?

Eh???

Lonny
05-09-2006, 03:37 PM
Is this product comparable to ephedra, meaning an someone sensitive to stimulants take it. That's why I liked blaze, because it was excellent for people who are sensitive to stimulants.

Also, can you drink coffee along with this?

I haven't tried it but from what I've been told, someone sensitive to stimulants will be sensitive to this due to the Tyramine and Caffeine. Check out some of the current logs to get an idea of just how stimulatory it is.

Depending on how you feel on it would be the measure of whether you could drink coffee. I don't see the extra caffeine being necessary but thats just my guess.

Lonny
05-09-2006, 03:40 PM
So you get 15 days worth from a bottle?

Eh???

I believe its 16 at the full dosage. You could run it at a 1 serving daily for 32 days if you are stimulant sensitive, or prefer longer lower dosed cutting phases.

KennyK
05-10-2006, 07:18 AM
I haven't tried it but from what I've been told, someone sensitive to stimulants will be sensitive to this due to the Tyramine and Caffeine. Check out some of the current logs to get an idea of just how stimulatory it is.

Depending on how you feel on it would be the measure of whether you could drink coffee. I don't see the extra caffeine being necessary but thats just my guess.


how is Tyramine comparable to Ephedre?. I'd like to try the product, but mentioning those two in the same paragraph is making me nervous.

Lonny
05-10-2006, 09:56 AM
how is Tyramine comparable to Ephedre?. I'd like to try the product, but mentioning those two in the same paragraph is making me nervous.

What is making you nervous about it?

KennyK
05-10-2006, 10:06 AM
What is making you nervous about it?


Maybe nervouse is too strong a word. I know Ephedrine was taken off the market due to health concernsand I'm just wary of taking anything that's similar to it.

But I'll probably end up trying xtreme anyway and cutting the dosage.

Lonny
05-10-2006, 10:35 AM
Maybe nervouse is too strong a word. I know Ephedrine was taken off the market due to health concernsand I'm just wary of taking anything that's similar to it.

But I'll probably end up trying xtreme anyway and cutting the dosage.

Ephedrine wasn't removed from the market, Ephedra was. And the health concerns were because people used it improperly. It was not dangerous when used properly, but when fat 40 year old housewives started taking it and not eating, there were problems.

Tyramine is similar in action but does not have the sides that ephedra does, as well it is also more effective.

KennyK
05-10-2006, 11:09 AM
Ephedrine wasn't removed from the market, Ephedra was. And the health concerns were because people used it improperly. It was not dangerous when used properly, but when fat 40 year old housewives started taking it and not eating, there were problems.

Tyramine is similar in action but does not have the sides that ephedra does, as well it is also more effective.

Thanks for the clarification.

I'll give it a try.
Any thoughts on SAN's sesamin product, i was going to stack it with blaze.

cakedonkey
05-10-2006, 11:11 AM
Thanks for the clarification.

I'll give it a try.
Any thoughts on SAN's sesamin product, i was going to stack it with blaze.

It would make for a very potent fat-loss stack, that's for sure. And you can be assured the sesamin's quality/purity because we can provide CoA's on every single product we offer.

Lonny
05-10-2006, 11:27 AM
Thanks for the clarification.

I'll give it a try.
Any thoughts on SAN's sesamin product, i was going to stack it with blaze.

Im currently using it and plan to use it year round. Check out the logs that are being done with Blaze Extreme+Sesamin.

KennyK
05-10-2006, 12:39 PM
Im currently using it and plan to use it year round. Check out the logs that are being done with Blaze Extreme+Sesamin.


Will do and keep me posted on your progess.

thx

hotasice2003
06-20-2006, 02:11 PM
Should an AI be run with this? I am just wondering about the conversion of 7-keto to estrogen......

musclescientist
06-20-2006, 03:10 PM
Should an AI be run with this? I am just wondering about the conversion of 7-keto to estrogen......

No AI needed. You are thinking of regular DHEA

DinoT1985
06-20-2006, 03:20 PM
Damn that looks good.

If this lives up to how great it is on paper, then I'll be buying it for my future cutting stack.

What other fat loss supps would compliment this besides sesamin?

hotasice2003
06-20-2006, 06:44 PM
No AI needed. You are thinking of regular DHEA


So, there is no fear of increased E levels?

daveburton
06-22-2006, 11:52 PM
So, there is no fear of increased E levels?

It is not possible for 7-keto-dhea to convert back into sex hormones. To answer your question, dont worry

Lonny
06-24-2006, 03:27 PM
Damn that looks good.

If this lives up to how great it is on paper, then I'll be buying it for my future cutting stack.

What other fat loss supps would compliment this besides sesamin?

Fish Oil and other healthy fats, Yerba Mate and Oolong teas would be my additions. Thyrocuts would be another option. And perhaps Vanquish for appetite.