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View Full Version : R-ala half life!



Q-dogg
10-13-2003, 11:47 AM
I think I read in a study that R-ala had an effective span that lasted 20min after ingestion to 12 hours. Now I cant find the study and think I might be making it up in my head!

Does this make sense?
Does R-Ala become effective after 20 minutes and last 12 hours?

Kraftydog
10-13-2003, 01:11 PM
I have no idea about half life, but they probably mean total excretion of the r-ala within 12hours of ingestion, thats my best guess.

I take glucorell, r-ala, 10 minutes prior to meals and that works great for me.

Q-dogg
10-13-2003, 01:24 PM
I was wondering this because I wanted to know if two 600mg doeses a day would cover 24 hours. I am constantly on the go and this would make dosing easy because I take R-ala poweder.
But if I am wasting it I want to know. Do I need to just take it before EACH meal, like 200-300mg, or two large doses like I described?

Kraftydog
10-13-2003, 01:27 PM
Originally posted by Q-dogg
I was wondering this because I wanted to know if two 600mg doeses a day would cover 24 hours. I am constantly on the go and this would make dosing easy because I take R-ala poweder.
But if I am wasting it I want to know. Do I need to just take it before EACH meal, like 200-300mg, or two large doses like I described?

in my experience before each meal.

Bond
10-13-2003, 01:47 PM
I take it throughout the day...

Kraftydog
10-14-2003, 02:00 AM
Originally posted by Johnny Bravo 00
I take it throughout the day...

same here, though only before my meals. Some people take glucorell before workouts because they say it improves fat loss for them. I have not tried it, but I am pretty sure it would give me low blood sugar.

Section 8
10-14-2003, 02:47 AM
Originally posted by Q-dogg
I was wondering this because I wanted to know if two 600mg doeses a day would cover 24 hours. I am constantly on the go and this would make dosing easy because I take R-ala poweder.
But if I am wasting it I want to know. Do I need to just take it before EACH meal, like 200-300mg, or two large doses like I described?

I haven't tried that myself, but I would think that 600mg of rLA would knock you into hypoglycemia real quick.

blinkboy99
10-14-2003, 05:52 AM
what does that mean?

CHUCK DIESEL
10-14-2003, 07:45 AM
"two 600mg doses" is 2 much, I know more is better in the US, but as an antioxidant, 200mg 2X a day is more than enough, take it with Vit C, selenium, other antioxidants that ALA recycles.

sawastea
10-14-2003, 08:30 AM
Originally posted by CHUCK DIESEL
"two 600mg doses" is 2 much, I know more is better in the US, but as an antioxidant, 200mg 2X a day is more than enough, take it with Vit C, selenium, other antioxidants that ALA recycles.

Not to mention very pricey as well :(

Are you referring to 600mg R+ or ALA??? 600mg R+/day is $$$$$

12 caps a day or R+ = 10 days for Glucorell

Q-dogg
10-14-2003, 09:09 AM
Yes I take R-ala powder, it burns.

I am not sure 1200mg daily is too much, a pubmed study showed remarkable resultes for insulin with 2g per day, though in rats.

I am not taking it prim. for antioxident effect, but for blood glucose.

I have not noticed hypoglycemia yet, even after not getting to food for 1 hour, but that was at 200mg's.

I have a retail store, so i also have connections to raw dealers who supply bigger company. So I get it cheap.

tanjhj
10-14-2003, 09:21 AM
For me,

as i am on low carb diet, 100mg-200mg of r-ala 10-15mins before my meal is areadi good enough.

btw i use mike's r-ala, i can confirm it is of quality stuff as after taking them, i can feel the r-ala working in my body.

Bond
10-14-2003, 10:04 AM
Originally posted by Kraftydog
Some people take glucorell before workouts because they say it improves fat loss for them.

I haven't heard that.... does anyone else have more info on that?

cjszip
10-14-2003, 10:11 AM
Most of the effect would probably be better reaped if taken in an effective dose with your highest carb meals where fat gain would be a concern. For example, I eat 110 carbs first thing in the morning, which also happens to be my pre workout meal, and I take 200 mg of R-ALA with this. My post workout shake comes directly after my workout, and then another 85 carbs are ingested 1 hour post workout with another 200mg R-ALA.

-cj

blinkboy99
10-14-2003, 03:07 PM
i do the same thing with reg ala
breakfast 400mg
pw shake 200mg
pw meal 600mg

thats pretty much all my carbs for the day, on higher carbs days i might have another 600mg with my dinner 2

Bond
10-14-2003, 04:26 PM
Originally posted by blinkboy99
i do the same thing with reg ala
breakfast 400mg
pw shake 200mg
pw meal 600mg

thats pretty much all my carbs for the day, on higher carbs days i might have another 600mg with my dinner 2 /

I do the same with ALA also but I take like half of it.... this is what I do:

Breakfast - 200mg
PW - 200mg
Meal 1-2h later - 200mg
Then I take another 200mg with dinner

blinkboy99
10-14-2003, 05:01 PM
do u feel ur getting all the advatages taking so litttle? ive read 10grams/carb...30 carbs=300 grams ala...and so on

covert ash
10-15-2003, 07:01 AM
Let's use a 200 mg serving of R-ALA. If the half life or R-ALA is 20 minutes, the breakdown would look something like this:

After 1st half life (20 minutes): 100 mg left
After 2nd half life (40 minutes): 50 mg left
After 3rd half life (60 minutes): 25 mg left
After 4th half life (80 minutes): 12.5 mg left
After 5th half life (100 minutes): 6.25 mg left
So on, so forth.

Anything, after the 5th or 6th half life isn't really considered significant anymore.

In other words, don't over analyze it. Splitting up your dosages throughout the day (ie. 600 mg, 3 times a day or maybe even 100 mg, 6 times a day) would be your best bet.

blinkboy99
10-15-2003, 09:34 AM
but wouldnt it be better to have 600 right before the carb meal than 100mg every 6 hours during hours u might not be eating carbs. i think before carb meals is the most optimal time

Q-dogg
10-15-2003, 10:46 AM
Could you elaborate?

So, do you mean if I ingest 200mg and then wait 20 minutes before drinking a carb shake containing 60g of carbs that my body is only really using 100mg of R-ala toward that 60g of carbs from the shake. I have been informed to consume my R-ala 20 minutes before ingestion of food. But it sounds like I am wasting half of it by your calculations. Is this right?

I thought I read a pubmed study that basically said that blood samples in mice where taken hours after ingestion of R-ala and that R-ala had an effect of blood glucose for up to 12 hours.

What are your calculations based on, do you have a link?
I an trying to find that pubmed study. Or does R-ala act differantly in the body once consumed versus what you tell me, could your data be R-ala's half life when exposed to air or something?

blinkboy99
10-15-2003, 11:20 AM
i dont think he claimed 20 min to be the halpf life he said for example

Q-dogg
10-15-2003, 11:31 AM
is that what he ment by using the word "if".....then I get that it is just an example right? Some one just let me know if I am on the right page. It was just an example right?

Kraftydog
10-15-2003, 12:15 PM
aren't biological half lives determined from estimated peak plasma?

anyways I just take my glucorell 10 minutes before meals. Works just fine. I find that it is better than taking it with meals, especially if they are "fast" carbs. If I take glucorell more than 1/2hr before I sometimes get low blood sugar, I am guessing the reason is that the expectation of food can actually causes some insulin release, at least that is what I have read. I usually take 3 caps though because I have a pretty high carb diet

Bond
10-15-2003, 12:56 PM
Originally posted by blinkboy99
do u feel ur getting all the advatages taking so litttle? ive read 10grams/carb...30 carbs=300 grams ala...and so on

I do see results... but yes maybe I should up that dosage....

covert ash
10-15-2003, 07:18 PM
Sorry if I threw everyone in for a loop: I meant for it as an example. I remember reading somewhere that the half life of R-ALA is relatively short but I don't know if it really is 20 minutes. The whole point was that we need not analyze this way too much.

Taking it in respectable divided dosages (Ex. 200 mg, 3 times a day) throughout the day (I probably should've said this in the first post) around the time of your meals with carbohydrates instead of one or two large doses will probably yield better results.

(Pure speculation and personal experience.)

In the end, K.I.S.S. (no offense)