best nitrix oxide supp?

[naturalguy]

I'm onto SAN fierce next! Somehow it doesn't get much attention here...
Ingredients looks good to me...

Fierce is very underrated on this forum

[brainrhodes]

Nitrix, Nitrous, WB, are all good choices for you. It also depends if you want creatine with your No2 or just No2 buy it's self.

[Joenonymous]

NO Shotgun is one of the best new products I've tried recently but unfortunately it tastes like death.

[IKTHOS]

WB is a very nice one, with a good profile, gives me very good pumps, I ve tried No xplode, good pumps in the begining, lots of gas, then u will need to increase the dose by time to get the same effect...

[ThaChach]

Animal Pump is awsome!! Great Pumps the best NO porduct I have tried yet..and ive used NO-Explode, Pump Tech, V-12 turbo, six-star, and a few others...

[rockhardabbs]

These are some good ones that I would recommend is Animal Pump, Nitrous and No-Xplod.

[Gym God]

I just jumped onto NiOx form Nutrex.

[benjioar]

Cool I would like to know how some of thier other products work. Please do a review and let us know what you think.

[mauller]

shock therapy is the best no if ands or buts.

Check out my new pics and tell me what you think!

[naturalguy]

shock therapy is the best no if ands or buts.

Check out my new pics and tell me what you think!

Your a big dude!

Shock is an awesome product

[aoba]

superpump250 seems to get the best results from people.

i personally LOVE White Blood, so i suggest either of these.

i'd avoid no2 prodcuts. if you relaly need the pump feeling just get some bulk Arginine Ethyl Ester or wait maybe for Gaspari Plasmajet.

if you have a weak stomach, i'd advise against sp250

[markedman]

Nitrous
NO Shotgun
Shock Therapy

Can't go wrong with any of those.

Yes agree those are some kick a$$ products.

[UnionHooligan]

Umm.... Yeah.... you know what you're talking about, lol.

NO products don't help you build muscle there is no scientific data to support it does anything more then give you a pump. I have done trial with them and have shown no notable increase in mass while taking them.

[fratboi850]

NO products don't help you build muscle there is no scientific data to support it does anything more then give you a pump. I have done trial with them and have shown no notable increase in mass while taking them.

I was about to post the same response but this guy beat me to it. NO does not help you build muscle it is basically a useless product marketed to high school and college kids to make money. If you really want to pay $50 bucks to get a pump for a couple weeks then by all means go ahead but its not a smart buy. And to the know-it-all who responded to my first comment go ahead and post some real evidence that NO helps build muscle for me... please, I would love to see it.

[NO HYPE]

"NO products don't help you build muscle there is no scientific data to support it does anything more then give you a pump."

Well I can see you don't do any research on scientific data then.

Sorry, but without the production of NO.... you wouldn't even have muscle.... let alone, build muscle.... in fact, you wouldn't even be alive.

So how is it that NO production within the body, doesn't assist in the building of muscle?

[NO HYPE]

"NO does not help you build muscle it is basically a useless product marketed to high school and college kids to make money."

umm.... actually it is an endogenous gas.... not a product.

[fratboi850]

Nitric Oxide Supplements- Big Claims - Zero Science: NO 2 ways about it.

by Paul Cribb, B.H.Sci HMS
AST Director of Research

Supplements that reportedly increase nitric oxide levels within the body are currently being marketed as powerful muscle builders. The marketers of these supplements claim they increase nitric oxide levels within muscle tissue and a dramatic increase in muscle size, strength is experienced. Other claims also include an increase in fast-twitch muscle fiber strength, endurance, power output, and load capacity from taking these supplements. These reported benefits are quite specific, so I decided to scan the literature for the scientific evidence that supports these claims.

Nitric Oxide – what is it?

Nitric oxide is a colorless, free radical gas commonly found in tissues of all mammals (it’s also prepared commercially by passing air through an electric arc). Biologically, nitric oxide has been shown to be an important neuro-messenger in a number of vertebrate signal transduction processes. Nitric oxide is used in medical treatment; for example, nitroglycerin ameliorates the pain of angina by supplying nitric oxide to the blood vessels that supply the heart. The popular drug Viagra controls erection by regulating nitric oxide in the penile cartilage chamber.

The Research and the Claims

I don’t know where the marketers obtained their literature on nitric oxide. It looks like they are using the same journals as the companies selling Myostatin inhibitors – Alice in Wonderland. Although nitric oxide acts as a cell-to-cell communicator for certain metabolic functions, muscle growth is not one of them. After a review of the available literature I cannot find any research that remotely indicates increasing nitric oxide levels plays a part in increasing protein synthesis, contractile strength or any other biochemical pathway that may lead to increases in muscle mass.

For a company to claim their supplement increases “fast-twitch” muscle strength, the promoters must have instigated or funded some kind of research that involved biopsy procedures and histochemical analyses to extract, assesses and identify these particular muscle fibers from animals or humans, before and after supplementation. However, I could find no documentation (either on their web sites or via a literature scan) that details these findings, only the marketing claims. As far as I’m aware, there is zero scientific evidence supporting the notion that nitric oxide supplements increase “fast-twitch” muscle strength.

There also appears to be no evidence whatsoever that shows increasing nitric oxide levels enhances endurance, power output, and load capacity.

Arginine alpha-ketogluterate is the “active” ingredient reported by one company that sells this type of supplement. It is claimed that this compound increases and maintains a constantly high level of nitric oxide in muscle. Nitric oxide is synthesized within the body using the amino acid arginine, the energy cyclic substrate NADPH, and oxygen. Nitric oxide diffuses freely across membranes but it is a transient signaling molecule. Nitric oxide is by nature, a highly reactive gas that has an extremely short life – less than a few seconds. While there is a lot of research on the effects of nitric oxide, there is no research that shows supplementation with arginine alpha-ketogluterate increases or sustains nitric oxide levels in any human or animal organs.

Can you imagine, a supplement that “creates dramatic increases in muscle size, strength, endurance, power output, and load capacity”, but not a single study to support these claims. Nothing new here. Unfortunately, this is typical sports nutrition marketing bull****. It's sad, misleading, and shows you just what these companies think of the intelligence level of their target market.

When new products burst onto the market, you the consumer can cut through the advertising hype quite easily. Simply ask the supplement company making the claims to "show you the research". A reference is a start, but the actual research study is particularly what your after. You want to see the study, the protocol, the outcome and the University at which the study was conducted. In the present case, you want to see a study showing were this supplement actually increased nitric oxide above a control group, and you want to see the data that demonstrates an increase in lean muscle mass, significantly more than the group without elevated nitric oxide levels.

The fact is, there is no science supporting any of the claims made for so-called nitric oxide supplements. There is no science showing they have any effect on nitric oxide levels and certainly no science showing in effects on muscle growth or increased performance.

Ask yourself why there is no research to support these companies’ wild claims. The simple answer is that research is expensive, make believe products are not. Research provides evidence, fraudulent supplement marketing only delivers hype. It’s far more financially rewarding to sell hype than to produce effective supplements backed by science.

One promoter of a nitric oxide supplement claims to have “brought creatine supplementation to the market” and that their supplement is “the perfected version of creatine”. I’m not sure which market is being referred to but creatine has been used as a supplement for over 40 years. And in NO way are nitric oxide supplements a “perfected version of creatine”. They are nothing like creatine. While creatine is backed by a wealth of research, nitric oxide supplements do not have a shred of scientific evidence that justifies their effectiveness as a bodybuilding supplements.

Bottom line, money spent on these products is money flushed down the toilet.

[triplewhammy]

Satur8 NO has actually been giving me really good pumps!


-triple

[NO HYPE]

"Nitric Oxide Supplements- Big Claims - Zero Science: NO 2 ways about it."

"Bottom line, money spent on these products is money flushed down the toilet."

That entire post was based on opinion and NOT scientific conclusion.

[fratboi850]

Bro, you know wanna know what gives me hyyooooooooge pumps!? Lifting weights! Seriously dawg you gotta try it! I get out of the gym and I'm like daaaaaamn dawg I'm ****in ripped!

But on a serious note, here is another article. Beyond that I dont really care if you want to buy this stuff and the fact of the matter is you havent posted any real scientific evidence that NO products build muscle because THERE IS NONE. Have a nice day!

www.t-nation.com/readTopic.do?id=556124

[NO HYPE]

Bro, you know wanna know what gives me hyyooooooooge pumps!? Lifting weights! Seriously dawg you gotta try it! I get out of the gym and I'm like daaaaaamn dawg I'm ****in ripped!

But on a serious note, here is another article. Beyond that I dont really care if you want to buy this stuff and the fact of the matter is you havent posted any real scientific evidence that NO products build muscle because THERE IS NONE. Have a nice day!

www.t-nation.com/readTopic.do?id=556124

My user name isn't NO HYPE for nothing.... so you can take your ignorance somewhere else now.... BYE!


(1) Combined inhibition of nitric oxide and prostaglandins reduces human skelatal muscle blood flow during exercise
http://jp.physoc.org/cgi/content/abstract/543/2/691

(2) Nitric oxide and prostaglandins influence local skelatal muscle blood flow during exercise in humans: coupling between local substrate uptake and blood flow
http://ajpregu.physiology.org/cgi/co...act/291/3/R803

(3) Physiology of Nitric Oxide in Skeletal Muscle
http://physrev.physiology.org/cgi/co...tract/81/1/209

(4) Nitric oxide synthase inhibition attenuates the skeletal muscle VEGF mRNA response to exercise (Vascular Endothelial Growth Factor/Messenger Ribonucleic Acid)
http://jap.physiology.org/cgi/conten...ract/88/4/1192



(1) "In conclusion, combined inhibition of NOS and PG reduced muscle blood flow during dynamic exercise in humans. These findings demonstrate an important synergistic role of NO and PG for skelatal muscle vasodilation and hyperaemia during muscular contraction."

(2) "These results show that NO and PG synergisically contribute to the local regulation of blood flow in skelatal muscle independently of muscle glucose uptake in healthy young men. Thus these vasodilators can play a role in regulating microvascular blood flow in localized regions of vastus lateralis muscle but do not influence regional glucose uptake. The findings suggest that local substrate uptake in skeletal muscle can be regulated independently of regional changes in blood flow."

(3) "Skeletal muscle functions regulated by NO or related molecules include force production (excitation-contraction coupling), autoregulation of blood flow, myocyte differentiation, respiration, and glucose homeostasis. These studies provide new insights into fundamental aspects of muscle physiology, cell biology, ion channel physiology, calcium homeostasis, signal transduction, and the biochemistry of redox-related systems.

(4) "These findings suggest that NO is important in the regulation of the VEGF gene response to exercise through increases in VEGF transcription or by increases in the VEGF mRNA half-life.

[NO HYPE]

My user name isn't NO HYPE for nothing.... so you can take your ignorance somewhere else now.... BYE!


(1) Combined inhibition of nitric oxide and prostaglandins reduces human skelatal muscle blood flow during exercise
http://jp.physoc.org/cgi/content/abstract/543/2/691

(2) Nitric oxide and prostaglandins influence local skelatal muscle blood flow during exercise in humans: coupling between local substrate uptake and blood flow
http://ajpregu.physiology.org/cgi/co...act/291/3/R803

(3) Physiology of Nitric Oxide in Skeletal Muscle
http://physrev.physiology.org/cgi/co...tract/81/1/209

(4) Nitric oxide synthase inhibition attenuates the skeletal muscle VEGF mRNA response to exercise (Vascular Endothelial Growth Factor/Messenger Ribonucleic Acid)
http://jap.physiology.org/cgi/conten...ract/88/4/1192



(1) "In conclusion, combined inhibition of NOS and PG reduced muscle blood flow during dynamic exercise in humans. These findings demonstrate an important synergistic role of NO and PG for skelatal muscle vasodilation and hyperaemia during muscular contraction."

(2) "These results show that NO and PG synergisically contribute to the local regulation of blood flow in skelatal muscle independently of muscle glucose uptake in healthy young men. Thus these vasodilators can play a role in regulating microvascular blood flow in localized regions of vastus lateralis muscle but do not influence regional glucose uptake. The findings suggest that local substrate uptake in skeletal muscle can be regulated independently of regional changes in blood flow."

(3) "Skeletal muscle functions regulated by NO or related molecules include force production (excitation-contraction coupling), autoregulation of blood flow, myocyte differentiation, respiration, and glucose homeostasis. These studies provide new insights into fundamental aspects of muscle physiology, cell biology, ion channel physiology, calcium homeostasis, signal transduction, and the biochemistry of redox-related systems.

(4) "These findings suggest that NO is important in the regulation of the VEGF gene response to exercise through increases in VEGF transcription or by increases in the VEGF mRNA half-life.

Bump.

[brucethejuice]

I a good stack that I have used my self and recommend to just about anyone looking for good pumps and good gains is the Swole Nitrous stack. Nitrous gets over looked alot on this board but it really is a great product. If you read some reviews you will see most people that stacked this with swole saw great results.

[Galvyn]

SuperPump 250 totally tore up my stomach. It's not even funny (yeah it is), but I had to stop taking NO-Xplode after a couple of weeks because it made me nauseous. After searching the BB.com Forums I found that Superpump 250 had a lot of good reviews. But let me tell you, a couple of scoops with a lot of water and 3 hours later I was in the toilet, then all nite and for a few days thereafter I had a stomach ache. I'm currently on Animal Pump (pills instead of powder) and its giving me good results.

[Forthecross11]

White Blood and Animal Pump

[naught33]

hey guys thanks for the input...ya id heard good stuff bout shock therapy and no shotgun...one of my training buddies just started no shotgun so ill let you all know what he thinks about it once he has been on it a few weeks

[jkdz3436]

The only down side I have heard about that is the taste. Other than that it looks like a great supplement. Good luck with it if that is what you are going with.

[naturalguy]

The only down side I have heard about that is the taste. Other than that it looks like a great supplement. Good luck with it if that is what you are going with.

I didn't think it taste that bad, it actually got better with time.