**WATER- The Ill Effects of Too Much H20**

**deserusan** · 10-21-2006, 04:31 PM

Originally Posted by Trung Q Pham, MD

Background: Hypernatremia is an electrolyte problem that is not uncommon, especially in elderly people who are hospitalized. Poor water intake, inability to express thirst, insensible water loss, or increased urinary water loss lead to dehydration and an increased concentration of serum electrolytes relative to water.

The development of hyperosmolality from the water loss leads to neuronal cell shrinkage and resultant brain injury. Loss of volume leads to circulatory problems (eg, tachycardia, hypotension). Water replacement can lead to cerebral edema.

Pathophysiology: The fundamental problem is that hypernatremia strictly defined is hyperosmolality, ie, an overall deficit of total body water. This deficit accrues by 2 mechanisms, which are inadequate fluid intake and water loss. Because thirst is a potent mechanism in the response to hyperosmolality, hypernatremia patients either have an inadequate thirst mechanism or have an inability to respond to thirst. If the thirst response to hyperosmolality is impaired, ongoing water losses raise serum sodium concentration. Ongoing water losses include insensible (always) water in excess of solute or renal loss (with a solute diuresis such as hyperglycemia or water diuresis). Increased sodium intake (salt tablets) is a rare cause of hypernatremia in hot, humid weather. The brain cell response to hypernatremia is critical and is contained in Image 1.

The keys to the pathophysiology of hypernatremia include the following:

Thirst should lead to water intake.

Vasopressin is critical to water reabsorption in the cortical collecting tubule.

The CNS is sensitive to changes in osmolality.

Water may be lost by renal and extrarenal mechanisms.

Frequency:

In the US: Overall, incidence ranges from 0.12-3.5% in hospitalized patients. Hypernatremia is most prevalent in the geriatric population.
Mortality/Morbidity:

The mortality rate across all age groups is approximately 45%.
The mortality rate in the geriatric age group is as high as 79%.
Race: No race predilection exists.

Sex:No sex predilection exists.

Age:

The groups most commonly affected are elderly people and young people.
People typically affected are aged 59-83 years.

After reading this I think I'm going to stop drinking water.

**Millennium 1** · 10-21-2006, 04:38 PM

Yeah, I think I'll switch to an all pepsi regimen. High fructose corn syrup sounds much safer now.

**deserusan** · 10-21-2006, 04:43 PM

Originally Posted by Millennium 1

Yeah, I think I'll switch to an all pepsi regimen. High fructose corn syrup sounds much safer now.

I'm going to avoid milk too because it contains both water and arachidonic acid. Sounds like a lethal combo.

**COOP1** · 10-21-2006, 04:43 PM

yea, stop drinking water. Its a great idea!

**deserusan** · 10-21-2006, 04:44 PM

Originally Posted by COOP1

yea, stop drinking water. Its a great idea!

Better safe than sorry

**Blap Blaow** · 10-21-2006, 04:44 PM

MATERIAL SAFETY DATA SHEET FOR DIHYDROGEN MONOXIDE

Should I be concerned about Dihydrogen Monoxide?

Yes, you should be concerned about DHMO! Although the U.S. Government and the Centers for Disease Control (CDC) do not classify Dihydrogen Monoxide as a toxic or carcinogenic substance (as it does with better known chemicals such as hydrochloric acid and benzene), DHMO is a constituent of many known toxic substances, diseases and disease-causing agents, environmental hazards and can even be lethal to humans in quantities as small as a thimbleful.

Research conducted by award-winning U.S. scientist Nathan Zohner concluded that roughly 86 percent of the population supports a ban on dihydrogen monoxide. Although his results are preliminary, Zohner believes people need to pay closer attention to the information presented to them regarding Dihydrogen Monoxide. He adds that if more people knew the truth about DHMO then studies like the one he conducted would not be necessary.

A similar study conducted by U.S. researchers Patrick K. McCluskey and Matthew Kulick also found that nearly 90 percent of the citizens participating in their study were willing to sign a petition to support an outright ban on the use of Dihydrogen Monoxide in the United States.

Is it true that using DHMO improves athletic performance?

Absolutely! With the numerous allegations of amateur and professional athletes using anabolic steroids and/or blood doping to enhance performance, virtually no attention has been paid to the performance enhancing properties of Dihydrogen Monoxide. It is perhaps the sporting world's dirtiest of dirty little secrets that athletes regularly ingest large quantities of DHMO in an effort to gain a competitive edge over an opponent.

One technique commonly used by endurance athletes in sports such as distance running and cycling is to take a large amount of DHMO immediately prior to a race. This is known within racing circles to dramatically improve performance.

Sports-medicine physicians warn that ingesting too much Dihydrogen Monoxide can lead to complications and unwanted side-effects, but do acknowledge the link to improved performance. DHMO is not currently considered a banned substance, so post-race urine tests do not detect elevated or abnormal levels of DHMO.

http://www.dhmo.org/facts.html

**Millennium 1** · 10-21-2006, 04:50 PM

Originally Posted by Blap Blaow

MATERIAL SAFETY DATA SHEET FOR DIHYDROGEN MONOXIDE

http://www.dhmo.org/facts.html

NICE!

***Zeus*** · 10-21-2006, 04:55 PM

About the whole hypernatremia argument...All you need is a pack of crackers or something with salt and sugar. Marathon runners get this often because they drink too much water and do not consume enough electrolytes. The human body can comfortably consume around 320z of water every 20 minutes. And if you are extremely dehydrated you should not chug water at your first chance to drink it, or else you might vomit only becoming more dehydrated. Water is necessary, however, and even when you are not thirsty you can still be dehydrated.

**deserusan** · 10-21-2006, 04:58 PM

Originally Posted by *Zeus*

About the whole hypernatremia argument...All you need is a pack of crackers or something with salt and sugar. Marathon runners get this often because they drink too much water and do not consume enough electrolytes. The human body can comfortably consume around 320z of water every 20 minutes. And if you are extremely dehydrated you should not chug water at your first chance to drink it, or else you might vomit only becoming more dehydrated. Water is necessary, however, and even when you are not thirsty you can still be dehydrated.

It still scares me. I'm letting my sink and shower run 24/7 to waste all the water so no one else will suffer from it.

**ENGMED** · 10-21-2006, 04:58 PM

Guys, too much water would be hyponatremia, not hypernatremia.

**Millennium 1** · 10-21-2006, 05:06 PM

People think you are serious Des! Funny!

**Harry83** · 10-21-2006, 05:09 PM

Originally Posted by ENGMED

Guys, too much water would be hyponatremia, not hypernatremia.

He's right...now I don't feel so stupid for being utterly confused by what you guys/that study was talking about haha...things just seemed...backwards?

Hyponatremia is defined as an abnormally low level of sodium ions in the blood, which can be caused by drinking too much water without adequately replacing electrolytes...

**deserusan** · 10-21-2006, 05:10 PM

Originally Posted by Millennium 1

People think you are serious Des! Funny!

*takes a sip of water* What are you talking about?

**Harry83** · 10-21-2006, 05:11 PM

Originally Posted by Millennium 1

People think you are serious Des! Funny!

Lol okay now I get it...I knew he was joking, just didn't know he was also joking about being completely backwards with the terminology lol

**Harry83** · 10-21-2006, 05:13 PM

Originally Posted by deserusan

*takes a sip of water* What are you talking about?

Damnit! Stop f*cking with my headdddd man....I'm currently experiencing neuronal cell shrinkage from a bad case of hyperosmolality...damnit just leave me alone lol

**chlaxman** · 10-21-2006, 05:36 PM

Originally Posted by ENGMED

Guys, too much water would be hyponatremia, not hypernatremia.

I was wondering when people were going to notice this was about the loss of water, not drinking too much.

**deserusan** · 10-21-2006, 05:36 PM

Originally Posted by Harry83

Damnit! Stop f*cking with my headdddd man....I'm currently experiencing neuronal cell shrinkage from a bad case of hyperosmolality...damnit just leave me alone lol

It's probably because you had too much water

**Stonecoldtruth** · 10-21-2006, 05:50 PM

I just drank a whole litre of water, now I'm worried it might kill me.. if I puke it back up does that make me bulimic? OMG... I'm skeered.

**chlaxman** · 10-21-2006, 05:52 PM

I don't know what is funnier: the talk in this thread or the fact that most don't even understand the article at all

**deserusan** · 10-21-2006, 05:53 PM

Originally Posted by chlaxman

I don't know what is funnier: the talk in this thread or the fact that most don't even understand the article at all

You are giving my wit a boner!

**factotum** · 10-21-2006, 06:03 PM

Another fantastic thread my firend, reps!!!

**BIG F@CE** · 10-21-2006, 07:32 PM

ive already given up water and now drink.......shampoo

**Coulaid** · 10-21-2006, 07:35 PM

Originally Posted by Blap Blaow

MATERIAL SAFETY DATA SHEET FOR DIHYDROGEN MONOXIDE

http://www.dhmo.org/facts.html

Dihydrogen Monoxide Needs to be BANNED ASAP!

**IntensityX** · 10-21-2006, 07:58 PM

Water is for sissys I drink pure 100% grade A pussy juice

**deserusan** · 10-21-2006, 11:47 PM

Originally Posted by IntensityX

Water is for sissys I drink pure 100% grade A pussy juice

WOW!

**factotum** · 10-22-2006, 10:28 AM

Originally Posted by IntensityX

Water is for sissys I drink pure 100% grade A pussy juice

Watch out for the smattering of man juice that's invariably mixed in. Might be part of the extraction procedure, not too sure. And the grade B ****, you don't even want to know where that comes from or what else is in it.

**Harry83** · 10-22-2006, 01:15 PM

Originally Posted by wanderlei

Watch out for the smattering of man juice that's invariably mixed in. Might be part of the extraction procedure, not too sure. And the grade B ****, you don't even want to know where that comes from or what else is in it.

The Grade B stuff is still good and effective as long as you increase your daily water intake by 128 additonal ounces!

**NoNameNecessary** · 10-22-2006, 01:41 PM

Originally Posted by IntensityX

Water is for sissys I drink pure 100% grade A pussy juice

Clearly, you haven't discovered the ethyl ester version. The esterification process makes it 300x more potent.

**OneBetter** · 10-22-2006, 01:42 PM

5 stars

**Kohen_Gadol** · 10-22-2006, 01:48 PM

Originally Posted by deserusan

After reading this I think I'm going to stop drinking water.

What about the new water methyl ethyl ester I am working on? You'll do it, run a log, whatever...

BK

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