ATHLETIC EDGE NUTRITION - IntraXCell - FAQ The DEFINITIVE Beta-Alanine/Carnosine post

[solarize]

IntraXCell

The World?s First Beta-Alanine, Carnosine Boosting Formula in convenient capsule form

When You Think of Beta-Alanine, We Dare You NOT to Think of IntraXCell

Boost Strength and Increase Lean Muscle Gains with IntraXCell!

History is about to be made once again!

Until now, creatine, with numerous research studies to support its effectiveness, was the leading supplement for improving exercise and muscular performance. Since creatine made its explosion into the sports nutrition world in the early nineties, our understanding of exercise physiology and sports nutrition has evolved exponentially. Recent research is giving rise to another supplement breakthrough?one that will change the direction of the industry like creatine did so many years ago. The research supported, IntraXCell* is THE next breakthrough supplement for increasing explosive strength, muscle mass and endurance.

IntraXCell Highlights:

• Boosts Explosive Muscular Strength & Power Output

• Increase Muscle Mass

• Increase Anaerobic Muscular Endurance

• Increase Aerobic Endurance

• Delay Muscular Fatigue - Train Harder & Longer

• Increase Muscle Fullness and Vascularity

• No Bloating or Water-Retention

Demand MORE from the brands you use, DEMAND Athletic Edge Nutrition!

While other supplement companies talk a big game, making unsubstantiated claims with no scientific support, Athletic Edge Nutrition is different. We are a NEW breed of supplement company. We raise the standard, by placing our exact formula (IntraXCell) through the rigors of a scientific research study. In doing so, we want to PROVE to you that IntraXCell delivers the promised results and will meet and exceed your highest expectations!

*Just In*: A research study, on 18 collegiate wrestlers using IntraXCell for 8 weeks, has just been completed. The results were staggering. IntraXCell caused HUGE increases in Anaerobic Strength, Power and Muscular Endurance!
*Kern BD, Robinson TL, Manninen AH. Effects of beta-alanine supplementation on exercise performance during a competitive wrestling season: An 8-week open label pilot study. (Manuscript under review).

http://forum.bodybuilding.com/showthread.php?t=2940681

More studies to come!


How does IntraXCell work?

While beta-alanine is largely responsible for the majority of performance benefits you gain from IntraXCell, there are other contributing factors to the science of IntraXCell. First, we will discuss some key issues occurring during exercise that limit us from reaching our strength and muscle mass goals. We will then explain just how IntraXCell's ingredients effectively targets these limitations.

What stops us from making NEW muscle gains, BIG increases in strength and limits us from reaching our full potential?

The sequence of events looks like this:

1. Our energy systems release large amounts of hydrogen ions(H+) during high intensity exercise.
2. H+ cause fatigue and cause your muscles pH to drop(become more acidic)
3. As our muscles pH quickly drops, so does your strength, while muscular fatigue increases
4. At the same time, fatigue causing free radicals are increased with exercise.

The Result of these events: Strength plummets, fatigue sets in and muscles are not adequately worked. Without sufficient overload, your muscles cannot and will NOT grow.


How can IntraXCell combat these events?

1. By utilizing a researched dose of beta-alanine, that dramatically boosts the levels of a powerful H+ buffer inside our muscles called carnosine.
2. Carnosine is a naturally occurring di-peptide that has the ability to stabilize muscular pH by soaking up (H+)
3. Carnosine is found in both type I and type II muscle fibers, but is highest in type II muscle fibers. Type II muscle fibers are primarily used in high intensity strength workouts and are most responsive to muscular growth.
4. By increasing carnosine concentrations in type II muscle fibers, you greatly enhance their ability to buffer/absorb increased amounts of H+ that are released during exercise.
5. Includes the antioxidants NAC, ALA and Vitamin E, which work along with carnosine to combat fatigue causing, free radicals.

The End Result: IntraXCell keeps us in an optimal pH range by buffering/absorbing H+, while simultaneously fighting fatigue-causing, free radicals. In doing so, our muscles are able to perform at much higher levels.

How do the other key ingredients in IntraXCell's formula work with the beta-alanine content and support intracellular carnosine levels?

One of carnosine's attributes beyond stabilizing muscular pH, is its ability to act as an intracellular antioxidant that can fight cellular fatigue. Knowing these secondary benefits of carnosine, we have combined other ingredients with beta-alanine that have the ability to boost yet another powerful intracellular antioxidant called glutathione. At the same time, the IntraXCell formula can directly work with carnosine's antioxidant ability.

1. N-Acetyl-L-Cysteine (NAC) - NAC increases glutathione levels inside the cell which is a power antioxidant that fights cellular fatigue. Interestingly beta-alanine has now been shown to increase the synthesis of glutathione by increasing the availability of its precursor cysteine. Beta-Alanine and NAC work perfectly together.
2. Vitamin E Vitamin E has been shown to increase carnosine levels more than carnsoine alone. Carnosine has been shown to increases Vitamin E antioxidant ability. These two operate hand in hand.
3. Alpha-Lipoic-Acid(ALA) ALA is a highly versatile antioxidant that boosts the above other two antioxidants, vitamin E and the end result of NAC supplementation,(increased glutathione levels).



Expect BIG GAINS in Strength, Muscle Mass & Endurance. Your workouts will NEVER be the same!




Available NOW at the bodybuilding.com store - http://www.bodybuilding.com/store/ae/intra.html


Our product summary review thread- http://forum.bodybuilding.com/showth...edge+nutrition

IntraXCell sport supplement product review in Muscular Development- http://forum.bodybuilding.com/showthread.php?t=1006794

Beta-Alanine(IntraXCell) study- http://forum.bodybuilding.com/showthread.php?t=2940681

Our beta-alanine article- science meets real world results, in Muscular Development- http://forum.bodybuilding.com/showthread.php?t=2524381

Our beta-alanine article: http://www.bodybuilding.com/fun/beta_alanine.htm

ATHLETIC EDGE NUTRITION interviews OLYMPIC hopeful Michael James!
http://forum.bodybuilding.com/showthread.php?t=940107

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Frequently Asked Questions


Q: Who can benefit from IntraXCell?

1. Individuals participating in weight training looking to gain lean muscle mass and increase strength.

2. Any individual involved in athletic activities where strength, power and muscular endurance are needed.

3. Active individuals who have reached a training plateau and are looking for something to take them to the next level.



Q: How long will it take for me to start noticing benefits?

Performance benefits typically start occurring in as little as two weeks, although some individuals will notice benefits within one week. As carnosine levels continue to increase, so will the benefits. The most dramatic results are generally experienced within the 3-4 week range, but they don?t stop there. Recent research is now showing carnosine levels continue to increase up to at least 12 weeks, so the benefits just keep on getting better which is why we recommend to continuously stay on IntraXCell for at least 3 months to optimize your carnosine levels.

Immediate benefits: Many users experience intense vasodilatation/pumps from the very first time they take their first does of IntraXCell. The reason this occurs is because Beta-Alanine increases carnosine and carnosine is a powerful precursor in generating nitric oxide synthase (NOS). NOS are a group of enzymes necessary for making the powerful vasodilator nitric oxide. Take IntraXCell with SteelEdge prior to exercise and let us know your experience. We are confident that you will be very pleased pumps/vasodilatation from your very first workout.

Q: At what point during my set will IntraXCell have its strongest effects?

IntraXCell, unlike creatine, is effective at all points during your set whether you're lifting heavy or doing endurance work. Your body uses three energy systems to perform work: the ATP-PC system, which is primarily used during heavy lifting and for sets in the 5-6 rep range; the glycolytic system, which is predominantly used roughly within the 7-15 rep range; and the oxidative/fat system which is used primarily in endurance training. Our energy systems are simultaneously utilized but depending on the level of intensity or duration, certain energy system will become more dominant. Anybody that trains with weights will use the first two systems predominantly and, in both cases, the result of the build-up of hydrogen ions will contribute to fatigue in both systems, especially glycolysis. This is where creatine falls a little short. It's mostly effective in the ATP-PC system which relies on ATP and phosphocreatine (PC) for intense, high-energy contractions. Taking creatine will help your explosive and maximal strength but it won't help you much in that 7-15 rep range. As anyone trying to build bigger muscles knows, you must train in both heavy and moderate (7-15 reps) ranges to gain lean mass. Only IntraXCell can fight the H+ build-up that occurs in both these ranges, allowing you to train at high levels regardless of your goals or your training intensity.

A recent study, in fact, showed that Beta-Alanine significantly outperformed creatine in decreasing cellular fatigue, giving it yet another advantage over what has been considered the most effective sport supplement of the last decade. With Beta-Alanine yielding impressive results in university-sponsored performance studies, creatine?s days at the top may be numbered.

Q: There are a few other beta-alanine, carnosine boosters out there, what makes IntraXCell different?

1. IntraXCell was the world's FIRST Dedicated beta-alanine, carnosine booster in convenient capsule form.
2. IntraXCell is the FIRST and ONLY stand alone beta-alanine formula that is backed by a research study
3. With IntraXCell, you get a large 4 gram dose of Beta-Alanine per day complying to the actual dosage used in the scientific research. Other carnosine boosters put beta-alanine in proprietary blends and do not list the amount, so it's impossible unless the company discloses the actual beta-alanine content for you to know if you are really getting a high enough dose to build up carnosine levels and reap all the benefits!
4. IntraXCell is designed with no stimulants so it can be taken anytime during the day everyday including late night workout sessions.
5. IntraXCell is a true carnosine booster without the unnecessary fluff that?s added to some of the other carnosine boosters currently on the market.


Q: How much Beta-Alanine is needed to cause performance increases?

Research has shown that you can take an amount between 3.2 grams and 6.4 grams per day to significantly boost carnosine levels and improve performance. The most recent research, now using 4-5 grams a day, is showing comparable carnosine concentration and performance improvements to those using 6.4 g daily.

Q: How long will a bottle of IntraXCell last me?

There are 60 servings in a bottle of IntraXCell. Two serving daily gives you exactly one month worth of product at 4 grams of Beta-Alanine per day, plus the highly beneficial NAC/ALA and Vitamin E.


Q: If one of the building blocks of carnosine is histidine, wouldn't it be beneficial to include it with beta-alanine to further boost muscle carnosine levels?

No, as histidine is already present in high concentrations in muscle, while beta-alanine is only present only in small amounts. Researchers have determined that it is beta-alanine that drives carnosine synthesis, not histidine. Since this has been proven repeatedly in research, there is no need to supplement with extra histidine to increase carnosine levels. There are potentially some select populations like vegans, vegetarians or the elderly that may not get enough histidine in their diets and are thus deficient, which may compromise optimal carnosine levels. But, we still don’t recommend taking just extra histidine with beta-alanine. Instead, we recommend these groups and simply bump up their total protein intake which will in turn solve their possible histidine deficiency. For the majority of healthy people, only beta-alanine is needed as histidine deficiency is rare and no extra supplementation is needed to increase carnosine concentrations.

Q: What other supplements do you recommend to maximize the results when taking IntraXCell?

1. We recommend our Full Spectrum Pre-Workout Formula, SteelEdge. SteelEdge contains many ingredients that enhance IntraXCell. On training days, take IntraXCell with SteelEdge to amplify the benefits of each product.

2. Creatine is another supplement that works well with IntraXCell and they can certainly be stacked together.


Q: Are there any methods that may increase beta-alanine's ability to increase Carnosine levels?

Yes, there are atleast two ways:

1. A recent study showed that a group of subjects taking Beta-Alanine with carbohydrates increased performance gains in half the time of the group taking an equal amount of beta-alanine without carbohydrates. Carbohydrates spike insulin and one of insulin’s effects is to increase amino acid (such as beta-alanine) transport into our cells.

2. Taking beta-alanine pre-workout and post-workout may increase the uptake of beta-alanine into our muscles. Amino acid nutrient timing studies have clearly shown when amino acids are ingested pre-workout and post-workout, their delivery and uptake into our muscles is increased. The improved uptake is largely due to increased blood flow during exercise. If you don’t find the prickling bothersome during your workouts, we suggest you take advantage of these two key windows of opportunity to maximize intramuscular beta-alanine uptake.

By combining the two above strategies, you will experience greater beta-alanine uptake, leading to faster performance increases.


Q: What is the prickling I feel when I first take IntraXCell?

The prickling - called parathesia - is caused by Beta-Alanine binding to nerve receptors, activating them and causing them to discharge/fire. Many of these nerves are below the skin, giving a prickling/pins-and-needles sensation. This sensation begins approximately 15-20 minutes after ingesting beta-alanine and usually continues for 1-1.5 hours. The intensity varies depending on dosing, individual sensitivity and potentially from activators of Ca2+ channels, such as caffeine.

This sensation, though generally enjoyed, often subsides over a few weeks of continued use. Carbohydrates/food may also blunt the prickling effect from beta-alanine.

[Outside backer]

looks really kick ass I love Beta alanine. ( h blocker) this being stim free is nice to take later in the evening. good luck with this i may try it out soon for comparison

[solarize]

If I don't feel the prickling does that mean beta alanine isn't working on me?

The prickling sensation does not occur at all in some individuals, even when taking 4-6 grams of beta-alanine at one time. Do not worry if you are in this group. The prickling is NOT a sign that beta-alanine is working or being absorbed by your muscles and converted to carnosine. If you are feeling nothing, you need not be concerned as it is still increasing your carnosine stores as research has repeatedly shown.

A good example of this phenomenon is when combining carbohydrates with beta-alanine. Not only do carbohydrates blunt much of the prickling sensations, they also increase beta-alanine's performance gains faster than beta-alanine without carbohydrates.

Another good example is comparing studies that measure carnosine concentrations using multiple small 800 mg doses of beta-alanine vs. studies using multiple doses of 1.6 g of beta-alanine. The total daily amount of beta-alanine ingested is similar and the duration of the studies using both dosage strategies is matched up as well. 800 mg is low enough to cause little to no prickling, based off feedback from both research and anecdotal, where as 1.6 g can cause quite a lot. The outcome of both studies showed carnosine concentrations were very similar.


Is taking taurine at the same time as beta-alanine going to stop beta-alanine from boosting carnosine and performance levels?

While there is certainly potential for problems when taking these two together (they share the same transporter into tissues), it hasn't yet been supported in the research to any level of significance. In fact, a recent study by Dr. Harris, showed that the increase in muscle carnosine with beta-alanine was not reduced when taurine was taken along with it.

We could get into the biochemistry of why taking taurine with beta-alanine may not seem like a good idea but we have a more simple and conclusive explanation just in case you wanted more proof to support Dr. Harris?s study. Since there is a group of studies that used either beta-alanine by itself or beta-alanine with taurine, we examined them to determine if there were any differences in the resulting carnosine concentrations. While more research is always needed, there are quite a few beta-alanine vs. beta-alanine plus taurine studies, and their outcomes are all the same. There is little to no difference in carnosine concentrations. In other words, taurine does not appear to inhibit beta-alanine from being absorbed to any level of significance, otherwise carnosine levels would have been lower in the beta-alanine plus taurine studies.

What about supposed taurine loss when taking beta-alanine?

This concern by some is based on some rat/cat studies that showed beta-alanine decreased the taurine content in the myocardium by half. These studies were using doses that are over 100 times higher than the highest Beta-alanine studies of 6.4 grams a day. These rat studies aren't even relevant to how we use beta-alanine in terms of dosage.

Beta-alanine does cause taurine levels to increase in the blood plasma, leading some to believe that we are actually losing alot of it from the body through excreting it in the urine. But from multiple studies now, the researchers have shown the taurine loss in the urine, is NOT at any level of significance.


Q: Are their any stimulants in IntraXCell that would prevent me from taking it for a late night training session?

No.

[Outside backer]

Ill Def keep an eye out good luck with it

[no_strain_no_ga]

Age for testing? Don't say 18 or older. I really want to try this product out and don't want my age to crash it down

[NumberTwentyTwo]

awsome company name, awsome product design

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We give a general warning that IntraXCell and SteelEdge are for those 18 and older. Of course, we can't stop you buying it and trying either product

Age for testing? Don't say 18 or older. I really want to try this product out and don't want my age to crash it down

[HalleluYAH]

Looks solid! I know AEN worked hard to ascertain the proper BA dosing. I look forward to giving this a try and comparing to other BA products I've used.

[no_strain_no_ga]

We give a general warning that IntraXCell and SteelEdge are for those 18 and older. Of course, we can't stop you buying it and trying either product

What people do that?

Thanks!

[pu12en12g]

Not bad... I'll probably give it a try sometime

[NATHAN518]

Looks solid! I know AEN worked hard to ascertain the proper BA dosing. I look forward to giving this a try and comparing to other BA products I've used.

exactly...these are research backed doses

excellent write up/FAQ as well

[ATHLETIC EDGE NUTRITION]

awsome company name, awsome product design

Thank you very much!

[Viator]

One thing people seem to be overlooking about IntraXcell is the NAC/Glutathione aspect. Oxidative damage occurring from prolonged, intense exercise can lead to some nasty conditions later in life. IntraXcell not only makes you stronger, but just may keep you healthy twenty or thirty years down the road.

[solarize]

Yup, the addition of NAC is often overlooked. It's well absorbed, resists enzymatic breakdown and has been shown to raise internal GSH and cysteine levels when taken orally. Also been shown to have immune support functions.

[factotum]

2XCell Blend: 4,202mg
(Beta-Alanine (4g), N-Acetyl L-Cysteine, Alpha-Lipoic Acid)

So let's assume there's 100 mg of NAC and 100mg of ALA, is that enough. Most studies with NAC use doses of 600mg or more and show over 2g to be pro-oxidative. IMO, 600-1000mg would be a better dosing of NAC. As for the ALA I guess 100mg may be enough but I think most people use 300mg.

Not bashing the product jsut wondering the reasoning for the doses.

[factotum]

I'm also wondering why carnosine wasn't used instead: it requires no conversion. But is is significantly more expensive hence why most products contain beta-alanine instead.

Beta-alanine is a competitive taurine transport inhibitor hence my preference to carnosine. I noticed Steel Edge contains Taurine so would stacking them pre workout reduce effectiveness of either since there compete for transportation into muscle?

[ATHLETIC EDGE NUTRITION]

I'm also wondering why carnosine wasn't used instead: it requires no conversion. But is is significantly more expensive hence why most products contain beta-alanine instead.

Beta-alanine is a competitive taurine transport inhibitor hence my preference to carnosine. I noticed Steel Edge contains Taurine so would stacking them pre workout reduce effectiveness of either since there compete for transportation into muscle?

Good questions Wanderlei...see my answers below:

Carnosine (which is a dipeptide of alanine and Histidine) is poorly absorbed through the GI tract and the little that survives intact gets broken down in the blood back into is building blocks BA and Histidine. Your body than takes take the two amino acids and rebuilds carnosine withinin the muscle.As you can tell, the reason for not taking straight carnosine is largely due to inefficiency issues.

Another common question is why not take both amino acids since you need both to build carnosine..see my anser below.


Since it's Beta-Alanine that is the rate limiting amino acid for carnosine synthesis, not histidine, taking straight carnosine is not an efficient way to boost intracellular carnosine levels. It is also very cost prohibitive to use straight carnosine at the doses needed to boost intramuscular carnsoine levels that cause performance increases.


And if that's not enough almost all the published research done on carnosine boosting performance it done with Beta-Alanine NOT carnosine. It is illogical from a scientific standpoint to take straight carnosine to boost intramuscular carnosine levels.

Taken from our above FAQ:

Q: If one of the building blocks of carnosine is histidine, wouldn't it be beneficial to include it with beta-alanine to further boost muscle carnosine levels?

No, it wouldn't. Histidine is already present in high concentrations in muscle, while beta-alanine is present only in small amounts. Scientists have determined and demonstrated that it is beta-alanine that drives the intra-muscular synthesis of carnosine, not histidine.





To answer your second question regarding Taurine and BA interfering with eachother, the answer is NO..


See below study, but before you read it, I want to let you know that many of the early human studies done on BA where done with EAS's phos****en Elite which contains a gram of taurine. In theory there could be absorption problems taking the two together due to them sharing similair transport mechanisms, but in reality it dosn't pan out to any level of significance in effecting BA's performance benefits.

We looked at this very closely before recommending taking IntraXCell with SteelEdge.



1: Amino Acids. 2006 Jul 28; [Epub ahead of print]Influence of beta-alanine supplementation on skeletal muscle carnosine concentrations and high intensity cycling capacity.
Hill CA, Harris RC, Kim HJ, Harris BD, Sale C, Boobis LH, Kim CK, Wise JA.
School of Sports, Exercise & Health Sciences, University of Chichester, Chichester, U.K..

Muscle carnosine synthesis is limited by the availability of beta-alanine. Thirteen male subjects were supplemented with beta-alanine (CarnoSyntrade mark) for 4 wks, 8 of these for 10 wks. A biopsy of the vastus lateralis was obtained from 6 of the 8 at 0, 4 and 10 wks. Subjects undertook a cycle capacity test to determine total work done (TWD) at 110% (CCT(110%)) of their maximum power (W(max)). Twelve matched subjects received a placebo. Eleven of these completed the CCT(110%) at 0 and 4 wks, and 8, 10 wks. Muscle biopsies were obtained from 5 of the 8 and one additional subject. Muscle carnosine was significantly increased by +58.8% and +80.1% after 4 and 10 wks beta-alanine supplementation. Carnosine, initially 1.71 times higher in type IIa fibres, increased equally in both type I and IIa fibres. No increase was seen in control subjects. Taurine was unchanged by 10 wks of supplementation. 4 wks beta-alanine supplementation resulted in a significant increase in TWD (+13.0%); with a further +3.2% increase at 10 wks. TWD was unchanged at 4 and 10 wks in the control subjects. The increase in TWD with supplementation followed the increase in muscle carnosine.

[DaveGabe24]

May be a simple question, and I may have overlooked the answer but are there any possibilities of losing any strength and/or size gains experienced while on, say a 10 week cycle of IntraXCell? It is probably safe to assume your Carnosine levels, as well as other things, will gradually degress back down to natural levels. Will this in turn effect your strength at the time?

[ATHLETIC EDGE NUTRITION]

May be a simple question, and I may have overlooked the answer but are there any possibilities of losing any strength and/or size gains experienced while on, say a 10 week cycle of IntraXCell? It is probably safe to assume your Carnosine levels, as well as other things, will gradually degress back down to natural levels. Will this in turn effect your strength at the time?

DG, I'm not sure if I understand your question properly, can you rephrase if for me please??

It sounds like you asking if you will lose strength gains while ON IntraXCell..is this correct??

Or do you mean to ask if you will lose your strength gains when you go off IntraXCell??

[Viator]

I think he's asking if you'll loose the increased carnosine stores and subsequent strength gains after ceasing use, similar to loosing AAS gains.

While I'm just speculating here, I would think that if it takes 3 months to build up the highest levels of carnosine stores in yr. muscles, then any loss of carnosine stores would take quite some time to decrease.

Another possible answer would be: the intra-cellular carnosine induced strength gains create new muscle, you stop taking IntraXcell, keep working out, and retain the muscle. Unlike AAS, where your hormone levels fall like a stock broker on a bad day, as do your gains.

As far as there only being 100 mg of NAC, some people will no doubt use more than the 6 cap dose, AND many other supps have NAC in them as well. Besides, Sebastian's one smart fella, every ingredient and every amount is in there for a reason. If I'm not mistaken, NAC + ALA have a synergystic effect on antioxidant levels, no?

[bongd]

Looks promising. I'll keep an eye on that as well.

Congrats on becoming a rep too, Viator.

[RB12]

looks like a pretty solid profile at a good price. can't wait to see some logs on this and hopefulyl try it myself soon.

[deserusan]

Looks like a good product and I'm definately new to beta-alanine supplementation. Eitherway, it's a great addition to any formula and I look forward to the feedback.

[Zachattack43]

I think its about time someone came out with a capped Beta Alanine product without stimulants and that is just basically BA, that way we dont have to buy it in bulk powder

[ATHLETIC EDGE NUTRITION]

I think its about time someone came out with a capped Beta Alanine product without stimulants and that is just basically BA, that way we dont have to buy it in bulk powder

Thank you, we obviously felt the same way

[ATHLETIC EDGE NUTRITION]

Looks like a good product and I'm definately new to beta-alanine supplementation. Eitherway, it's a great addition to any formula and I look forward to the feedback.

Thank you Des and hopefully we can have you do a review of IntraXCell or SteelEdge in the near future as I have always enjoyed and respected your thorough and unbiased reviews.

I also know much credibility your name carries here on bb.com.


We are likely going to start choosing testers for logs next week and I will personally keep you posted

[B1CEPS]

hey i see that the directions are to take one serving per day (4g beta alanine), were as Biotest version is one serving (2g beta alanine) 2-3 times a day!

Which protocol is the best, one large dose or smaller more frequent doses??!!??

Any ideas?

[solarize]

Reading through the literature, I think either way is fine.
Single dosing (which we recommend) is more convienient and AFAIK L-carnosine will be elevated in a similar fashion from single or multiple doses, with an increase in L-carnosine proportional to the dosage of beta-alanine, up to an as yet undetermined maximum.

IntraXCell can be spread out into multiple doses if people prefer.

Current research has used doses of 3.2 and 6.4g a day with an increase in L-carnosine 42.1% and 64.2% respective.

hey i see that the directions are to take one serving per day (4g beta alanine), were as Biotest version is one serving (2g beta alanine) 2-3 times a day!

Which protocol is the best, one large dose or smaller more frequent doses??!!??

Any ideas?

[ATHLETIC EDGE NUTRITION]

So let's assume there's 100 mg of NAC and 100mg of ALA, is that enough. Most studies with NAC use doses of 600mg or more and show over 2g to be pro-oxidative. IMO, 600-1000mg would be a better dosing of NAC. As for the ALA I guess 100mg may be enough but I think most people use 300mg.

Not bashing the product jsut wondering the reasoning for the doses.

NAC builds up intracellular Glutathione levels over time much like Beta-Alanine builds up intracellular carnosine over time, there is no set efficacious dosage when taking NAC to boost glutathione concentrations.

Having said that, there is no harm in adding 200-400mg's of extra NAC if you so chose. And yes a gram or more of NAC can have pro oxidant effects, so there is no need to go too crazy with adding extra NAC with IntraXCell. The above range of 200-400mg of NAC will be more than sufficient if you really want to boost up your intake.