Just looking to see if anybody has any experience with high doses of r-ala during cutting. Was thinking about taking 400mg with every carbs meal. Might only be able to poteniate insulin so much, but I'm not sure.
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Thread: Mega Dosing R-ala
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06-17-2006, 07:37 AM #1
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06-17-2006, 01:53 PM #2
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06-17-2006, 02:05 PM #3
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This is Layne's article, and it says to either go with 600mg or 1200mg. I don't know about anything higher than that. IMO if you go higher, you want to think about hypoglycemia.
http://www.bodybuilding.com/fun/layne25.htm
I, personally, take 200mg 3 times a day, and are cutting. When I bulk, I will take it prolly 6 times a day........Currently: Bulking
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06-17-2006, 02:16 PM #4
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06-17-2006, 02:35 PM #5
Very nice study indeed. Keep in mind though that they used ALA. The S isomer in ALA cancels the benefits of the R-isomer so you can probably obtain the same benefits from, say, 600mg of R-ALA.
Careful with megadosing though, once I took close to 2 grams of K-R-ALA and almost passed out. I think 100-150mg of R-ALA for every 50g of carbs is reasonable.
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06-17-2006, 07:58 PM #6
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06-17-2006, 08:34 PM #7
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06-17-2006, 09:18 PM #8
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06-17-2006, 09:31 PM #9
Isn't the point of R-ALA to increase insulin production, if so then wouldn't you want to take it at certain times of the day like in the morning and post-work out to increase/rebuild your glycogen storage and the excess will be stored as fat. So if you increase insulin later during the day, wouldn't it increase fat storage? I dunno that was just the understanding i had, please correct me if i'm wrong.
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06-17-2006, 09:35 PM #10
I don't understand why anyone would ever want to increase insulin besides pre-during-post-workout. Could someone explain this?
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06-17-2006, 09:38 PM #11
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06-17-2006, 11:53 PM #12
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06-18-2006, 12:45 AM #13
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06-18-2006, 07:08 AM #14
it really is an interesting supp. While I don't see any difference between Glucophase as I do with r-ala( 1 GP post workout and 1 with cheat meal, r-ala at other times) I do think that some form of r-ala is a staple. That being said I wouldn't rely too heavily on high dosages for 2 long. I think of dosage of 600mg's is good, though spread out with 100mg's per meal
Chicks dig big calves
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06-18-2006, 07:53 AM #15
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06-18-2006, 08:35 AM #16
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06-18-2006, 08:36 AM #17
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06-18-2006, 09:14 AM #18
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06-18-2006, 09:54 AM #19
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06-18-2006, 10:29 AM #20Originally Posted by Dimitar
There is absolutely no scientific proof for this statement. This is only theorized. All of the benefits of ALA have been proven in studies that have only used ALA. To my knowledge there is not a single study where only R-ala has been used or the new K-r-ala. All of the benefits of r-ala and k-r-ala are only based upon theory and anectdoctal reports.
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06-18-2006, 10:30 AM #21
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06-18-2006, 11:06 AM #22
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06-19-2006, 09:40 AM #23
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Originally Posted by whitedevil74
you gotta get water sol. and fat sol antioxidants.......at a min....
1,000mg Vit C a day, pref. 500mg 2X a day bc its only water sol. so it leaves the body fast.
ALA anywhere from 50mg to 300mg a day.
then some "next level" antioxidants like grape seed, pine bark, etc..,
Rosemary is a good antioxidant also.
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06-19-2006, 09:49 AM #24
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Originally Posted by whitedevil74
I dont mean to be rough, but most of the time now, consumers are mis-educated on how substances work in the body and most of the rec. dosages people pull out their ass is mostly to sell more product.
there is an article in the latest Planet Muscle and someone from the suppliers of kre-alk is recommeding like 10g of kre-alk pre-workout. How can something be so much stronger than reg. creatine mono. and they are rec. more of it than mono? To sell more. U only need about 5g of kre-alk/day at the high end.
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06-19-2006, 09:51 AM #25
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People came up with the idea that 1200mg of ALA was effective back when all we had were crappy ALA supps. K-R-ALA seems to work just as good in small doses (like that in GXR, which is actually 100mg of R-ALA). I think at most you'd take 200mg (2 GXR's) with one meal, but that is only if it has quite a large amount of carbs.
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06-19-2006, 09:52 AM #26
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06-19-2006, 09:58 AM #27
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also that article does use and talk about ALA (s and r) not r ala which is about (or maybe) 2X as effective as a combination of both BUT regular ala does work and is a more cost effective form.
from the article:
"Maddux et. al, found that both isomers of lipoic acid were equally effective in preventing oxidative stress induced impairment of glucose transport6. Rudich et. al., found that S-LA was more effective than R-LA in protecting against oxidant induced insulin action impairment in 3T3-L1 adipocytes [4]."
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06-19-2006, 10:01 AM #28
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06-19-2006, 10:32 AM #29Originally Posted by gaberox
Originally Posted by pubmedYes, there is indeed a deeper component to it all.
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06-19-2006, 12:00 PM #30
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