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  1. #1
    Registered User HalleluYAH's Avatar
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    Question Abstract: Failure to repeatedly supercompensate muscle glycogen stores in...

    Please read the study below, and provide feedback... not sure what to make of this... though the study was done on cyclists, not bodybuilders (aren't they all )...

    Failure to repeatedly supercompensate muscle glycogen stores in highly trained men.

    McInerney P, Lessard SJ, Burke LM, Coffey VG, Lo Giudice SL, Southgate RJ, Hawley JA.

    Exercise Metabolism Group, School of Medical Sciences, RMIT University, Victoria, AUSTRALIA.

    PURPOSE: It is not known whether it is possible to repeatedly supercompensate muscle glycogen stores after exhaustive exercise bouts undertaken within several days. METHODS: We evaluated the effect of repeated exercise-diet manipulation on muscle glycogen and triacylglycerol (IMTG) metabolism and exercise capacity in six well-trained subjects who completed an intermittent, exhaustive cycling protocol (EX) on three occasions separated by 48 h (i.e., days 1, 3, and 5) in a 5-d period. Twenty-four hours before day 1, subjects consumed a moderate (6 g.kg)-carbohydrate (CHO) diet, followed by 5 d of a high (12 g.kg.d)-CHO diet. Muscle biopsies were taken at rest, immediately post-EX on days 1, 3, and 5, and after 3 h of recovery on days 1 and 3. RESULTS: Compared with day 1, resting muscle [glycogen] was elevated on day 3 but not day 5 (435+/-57 vs 713+/-60 vs 409+/-40 mmol.kg, P<0.001). [IMTG] was reduced by 28% (P<0.05) after EX on day 1, but post-EX levels on days 3 and 5 were similar to rest. EX was enhanced on days 3 and 5 compared with day 1 (31.9+/-2.5 and 35.4+/-3.8 vs 24.1+/-1.4 kJ.kg, P<0.05). Glycogen synthase activity at rest and immediately post-EX was similar between trials. Additionally, the rates of muscle glycogen accumulation were similar during the 3-h recovery period on days 1 and 3. CONCLUSION: We show that well-trained men cannot repeatedly supercompensate muscle [glycogen] after glycogen-depleting exercise and 2 d of a high-CHO diet, suggesting that the mechanisms responsible for glycogen accumulation are attenuated as a consequence of successive days of glycogen-depleting exercise.
    Psalms 51:10-13
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  2. #2
    Registered User Hercule's Avatar
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    So on day 3 their post exercise glycogen stores were much higher than on day 1 or 5.

    Can't really think of anything useful to conclude from this data, maybe day 3 was a lighter work out and the whole thing is ****ed.
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    Registered User hotasice2003's Avatar
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    What answers, specifically, are you looking for Hal?
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    Registered User mm312740's Avatar
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    It appears to me that it is almost saying that these well trained men got in better shape after the first workout, or after they did it once there bodies were better prepared for the 2nd and 3rd trial. Glycogen seemed to be restored faster, or possibily not depleted as much during the exercise, on the last 2 days.

    To really get anything out of this i think they should have conducted the trial for much longer than 3 exerciseing days, possibily 2 or more weeks and that way we could see if it stoped depleting as much.

    I also dont know if this has much to do with bodybulding and just more with exercise science in general.
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    Registered User Hercule's Avatar
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    Originally Posted by mm312740
    It appears to me that it is almost saying that these well trained men got in better shape after the first workout, or after they did it once there bodies were better prepared for the 2nd and 3rd trial. Glycogen seemed to be restored faster, or possibily not depleted as much during the exercise, on the last 2 days.

    If you look day 5 is worse than day 1.
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  6. #6
    Registered User HalleluYAH's Avatar
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    I am going to post this abstract at Alan Aragon's Pre/Post Workout thread in the nutrition forum for his feedback. Appears to me that doing high intensity exercise on 3-5 consecutive days can attenuate (lessen) our bodies ability to repidly replenish glycogen as opposed to only 1 or perhaps 2 consecutive days.
    Psalms 51:10-13
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