Im not going to answer any questions about Dutasteride, Im only posting this because everyone is pushing this as a new anti-hairloss drug.
Just an FYI about Dutasteride vs Finasteride. Dutasteride elminates 95% of the bodies DHT. Not good at all for so many reasons. Finasteride elminates 70% of the bodies DHT. Finasteride lowers DHT on the scalp by about 30% (where it counts). Dutasteride is better at the scalp by so little, its hardly worth mentioning. Dutasteride is a horrible compound to release on the public, like it will do any better on the hair. Deception.
DHT is an estrogen antagonist. Removal of that high of an amount will allow estrogen to run loco. Increasing the likelyhood of gyno.
Now I know they 'claim' low sides, but a 95% elmination of DHT is major. Them calling it superior for hair is true but deceiving. It is superior by a very small amount, certainly not worth what it does to your body. Excessive DHT is bad for the hair and prostate if you have a genetic predisposition to these things, but elminating too much DHT will have serious consequences. I think that people think that a DHT blocker on-cycle will be helpful in blocking androgenic effects.
.5mg pills of Avodart (dutasteride) is what it comes in, and yes it is bad to remove that much DHT from your body, and it wont make a difference on hair that you will see. 95% DHT is a lot. 2.5mg once a week is the usual dosing for hair.
* Duration of Side Effects
The greatest concern however, is the potential duration of side effects. The long half life of dutasteride exceeds 240 hours vs. the rather short 6 to 8 hours for finasteride. There have been some cases where the DHT levels were still had only returned to 25% of their original levels nearly a YEAR after having discontinued Dutasteride. As a result, any dangers or side effects that may be seen from Avodart, whether directly related or as a hypersensitive or allergic reaction may take literally months to resolve.
* Conversely, there is no biological model for 5AR type 1 deficiency, which Avodart creates, and there are measurable levels of 5AR-1 in the human brain. Conclusion -- the blockage of 5AR-1 may have yet unknown neurological implications.
* Remember Fen-Fen for weight loss? Personally, I do not want my patients to be the guinea pigs.
If you still want to take it after this, knock yourself out. I would not.
There are NO long term studies on Dutasteride.
Some of this was cut & paste.