losing fat on the face

[icecreamman]

hi, i have a pretty good body physique but my face is quite fat. i mean, i have chubby cheeks and can't see my jawline. it looks/feels awkward. what can i do to reduce only on my face/neck?

thanks

[Kraftydog]

hi, i have a pretty good body physique but my face is quite fat. i mean, i have chubby cheeks and can't see my jawline. it looks/feels awkward. what can i do to reduce only on my face/neck?

thanks

yohimburn es

http://www.irontrybe.com/forum/showthread.php?t=1871
http://www.elitefitness.com/forum/sh...d.php?t=395864

[Abyss]

Can a person use this thing even if he hase'nt even tried losing weight, and just use it on ur face while dieting down or something, will it work?


And can u get this from a pharmacy?

[Kraftydog]

Can a person use this thing even if he hase'nt even tried losing weight, and just use it on ur face while dieting down or something, will it work?


And can u get this from a pharmacy?

if you are in a calorie deficit, yes.

try www.yohimburn.com
i am pretty sure they have a list of retailers
still not sure why bb.com does not carry it.

[Joe00224223]

hi, i have a pretty good body physique but my face is quite fat. i mean, i have chubby cheeks and can't see my jawline. it looks/feels awkward. what can i do to reduce only on my face/neck?

thanks

Youve been taking creatine while cutting, havent you?

[Adam444]

Secret:

Clean Diet + Cardio.


Wait... you already knew that.

[DJohnson]

Meh, I'm getting pretty lean and my face is pretty fat still. I'll probably try this.

[supplementsavvy]

I found that Lipoderm Y was helpful..adds a little extra definition. But yeah...decreasing bodyfat even further is most important.

[Pump_30]

Secret:

Clean Diet + Cardio.


Wait... you already knew that.

Like Adam says.........clean up ur diet and do cardio if you get down to 8-10% bf ur jaw line will mysteriously appear again.....

[outbreak]

if you are in a calorie deficit, yes.

try www.yohimburn.com
i am pretty sure they have a list of retailers
still not sure why bb.com does not carry it.

They don't stock it because it most likely doesn't work.

[Dahon]

Do you have a picture to show us how you look?

[TurboGuy]

You cannot spot reduce. You own body's physiology determines where fat is stored or burned based on diet and exercise. Your only real solution is to continue dieting under a calorie deficet, lift and cardio. The synergy of the 3 will help maximize fat loss. You can then pray that fat comes off your face moreso than other areas.

I think you are pissing in the wind with topical fat creams, but that is merely my opinion, with no evidence to support it.

[IRCRomeo]

Meh, I'm getting pretty lean and my face is pretty fat still. I'll probably try this.

I'm the opposite. My own father says I'm too thin based on my face, as it is very lean. I'm 6"0', 180lbs, and 12.5%bf. I'm still trying to cut but the ignorant don't see the point.

[Kraftydog]

They don't stock it because it most likely doesn't work.

thats definitely not the case. My guess is lack of advertising support.

bb.com carries
http://www.bodybuilding.com/store/ultra/beast.html
this is complete crap

http://www.bodybuilding.com/store/mm/mm.htm
FTC and FDA fines- do a search on creatine serum

http://www.bodybuilding.com/store/nutra/cutting.html
this is the most returned item in the HISTORY of GNC

they carry whats advertised and what they can buy cheap and sell high (like any business). I guess whatever deal that Anafit offered them was not profitable enough

[Kraftydog]

You cannot spot reduce.

this is a myth, there are lots of ways to spot reduce topical yohimbine is just one of them.

spot reduction via exercise is still widely debated (its not a settled issue)

[TurboGuy]

this is a myth, there are lots of ways to spot reduce topical yohimbine is just one of them.

spot reduction via exercise is still widely debated (its not a settled issue)

It's not a myth, its a theory, and there is a lot of supporting evidence, which you can't say about spot fat reduction. Not to mention the countless experience from professionals in the personal training industry.

I think the gereral medical community will attest to fallicy of fat spot reduction with resistance training. But if you think it works for you, more power to you.

[TurboGuy]

...topical yohimbine is just one of them.

There are lots of pills available that will help me enlarge my penis too. And my wife's breast size. . . . Doesn't make it a reality though.

[Kraftydog]

I think the gereral medical community will attest to fallicy of fat spot reduction with resistance training. But if you think it works for you, more power to you.

that would be the same medical community that said steroids would not increase muscle mass (the merck manual indicated thus for nearly 20 years, not until 5 or 6 years ago was this changed).

in the research community there is still debate on spot fat reduction via endurance/resistance training. simple resistance training is certainly less likely to cause the metabolic changes that might lead to local fat store reduction.

[Kraftydog]

There are lots of pills available that will help me enlarge my penis too. And my wife's breast size. . . . Doesn't make it a reality though.

you are right, just because their is a product does not mean it works. However, in this case there are effective spot reducers.

here are some examples of actual drugs that spot reduce
HGH
PGF2A- via apoptosis
deoxycholate- detergent- non specific cell lysis
Yohimbine via A2 adrenoceptor blockade

now with yohimbine unless you have high concentrations of A2 receptors its not going to do as much for you, of course if you did not have those high concentrations of A2 receptors you would not have disproportionate stubborn fat pockets.

[Joe00224223]

answer my question

HAVE YOU BEEN TAKING CREATINE WHILE CUTTING?

it causes retention of fat in the facial area. its well documented.

[DJohnson]

answer my question

HAVE YOU BEEN TAKING CREATINE WHILE CUTTING?

it causes retention of fat in the facial area. its well documented.

I have. Where is this documentation?

[Kraftydog]

answer my question

HAVE YOU BEEN TAKING CREATINE WHILE CUTTING?

it causes retention of fat in the facial area. its well documented.

creatine monohydrate can cause subcutaneous water retention, but its all over and not just local to the face.

this is not an issue with CEE

[Graphite]

My jawline is SUPER cut but the place lays under my chin. :/

[Joe00224223]

I have. Where is this documentation?

Google it.

Its gotten to the point where doctors are considering prescibing creatine to AIDS cases because of the facial fat atrophy caused by some AIDS meds.

Ive read of about 100 cases where people say theyve been on creatine and there face has gotten fat.

Go off the creatine, and start losing weight, youll see the difference in your face in no time. Or just dont listen to me and dont ever lose the facial fat.

Creatine does indeed cause water retention...but this is a seperate issue.

CEE may work differently, I dont know, I havent tried it yet.

[Kraftydog]

Google it.

Its gotten to the point where doctors are considering prescibing creatine to AIDS cases because of the facial fat atrophy caused by some AIDS meds.

Ive read of about 100 cases where people say theyve been on creatine and there face has gotten fat.

actually all the aids sites doctors say the opposite, that it will not increase face fat. if you have some links to such reports. they would be helpful, though you should also take into account that they are aids patients and it might be possible that its a metabolic offset to one of the issues caused by thier disease or drugs (in theory)

[Joe00224223]

I clearly just ****ing said google it, google -creatine and face fat- or -creatine and facial fat- and youll find dozens of reports.

Its a fairly simple experiment, go off the creatine and cut and look at your face.

[mondesi02]

this is a myth, there are lots of ways to spot reduce topical yohimbine is just one of them.

spot reduction via exercise is still widely debated (its not a settled issue)

You can't spot reduce, ...You usually lose it the last place you see it.

...

[Dahon]

Is it possible to lose weight and your face is still fat? I mean there's no exercise to make the face skinner. I notice that my face has gotten a little skinnier. I was 5'10 and 265 and now I'm down to 235. However, my face is still fat. 235 is still fat for my height. Lately, Ive been taking some pictures and I have noticed it. I'm trying to up my cardio to 4-5 times a week for 45-60 minutes.

[Kraftydog]

You can't spot reduce, ...You usually lose it the last place you see it.

...

sorry, but you really ought to rethink that position.

I am not reccomending deoxycholate, so the first study is just for emphasis

J Am Acad Dermatol. 2005 Dec;53(6):973-8. Epub 2005 Oct 19. Related Articles, Links


Lipomas treated with subcutaneous deoxycholate injections.

Rotunda AM, Ablon G, Kolodney MS.

Division of Dermatology, University of California Los Angeles, David Geffen School of Medicine, Los Angeles, California, USA. arotunda@hotmail.com

BACKGROUND: Lipomas are benign neoplasms of mature fat cells. Current treatments are invasive and carry the risk of scarring. Injections of phosphatidylcholine solubilized with deoxycholate, a bile salt, have been used to reduce unwanted accumulations of fat. Recent in vitro and ex vivo investigations indicate that deoxycholate alone causes adipocyte lysis. OBJECTIVE: We sought to report our experience treating lipomas using subcutaneous deoxycholate injections. METHODS: A total of 6 patients presenting with 12 lipomas were treated with intralesional injections of sodium deoxycholate (1.0%, 2.5%, and 5.0%) at intervals of 2 to 20 weeks. Tumor size, cutaneous reactions, and patients' subjective responses were recorded before and after treatment. RESULTS: All lipomas decreased in size (mean area reduction, 75%; range, 37%-100%) as determined by clinical measurement (with ultrasound confirmation in one lipoma) after an average of 2.2 treatments. Several lipomas fragmented or became softer in addition to decreasing in volume. Adverse effects, including transient burning, erythema, and local swelling, were associated with higher deoxycholate concentrations but resolved without intervention. There was no clear association between deoxycholate concentration and efficacy. CONCLUSIONS: Our clinical experience supports our laboratory investigations demonstrating that deoxycholate, rather than phosphatidylcholine, is the active ingredient in subcutaneously injected formulas used to treat adipose tissue. This small series suggests that low concentration deoxycholate may be a relatively safe and effective treatment for small collections of fat. However, controlled clinical trials will be necessary to substantiate these observations.

Am J Physiol Endocrinol Metab. 2005 May;288(5):E957-64. Epub 2004 Dec 21. Related Articles, Links


Dehydroepiandrosterone inhibits the amplification of glucocorticoid action in adipose tissue.

Apostolova G, Schweizer RA, Balazs Z, Kostadinova RM, Odermatt A.

Division of Nephrology and Hypertension, Department of Clinical Research, University of Berne, Freiburgstrasse 15, 3010 Berne, Switzerland.

Dehydroepiandrosterone (DHEA) exerts beneficial effects on blood glucose levels and insulin sensitivity in obese rodents and humans, resembling the effects of peroxisome proliferator-activated receptor-gamma (PPARgamma) ligands and opposing those of glucocorticoids; however, the underlying mechanisms remain unclear. Glucocorticoids are reactivated locally by 11beta-hydroxysteroid dehydrogenase type 1 (11beta-HSD1), which is currently considered as a promising target for the treatment of obesity and diabetes. Using differentiated 3T3-L1 adipocytes, we show that DHEA causes downregulation of 11beta-HSD1 and dose-dependent reduction of its oxoreductase activity. The effects of DHEA were comparable with those of the PPARgamma agonist rosiglitazone but not additive. Furthermore, DHEA reduced the expression of hexose-6-phosphate dehydrogenase, which stimulates the oxoreductase activity of 11beta-HSD1. These findings were confirmed in white adipose tissue and in liver from DHEA-treated C57BL/6J mice. Analysis of the transcription factors involved in the DHEA-dependent regulation of 11beta-HSD1 expression revealed a switch in CCAAT/enhancer-binding protein (C/EBP) expression. C/EBPalpha, a potent activator of 11beta-HSD1 gene transcription, was downregulated in 3T3-L1 adipocytes and in liver and adipose tissue of DHEA-treated mice, whereas C/EBPbeta and C/EBPdelta, attenuating the effect of C/EBPalpha, were unchanged or elevated. Our results further suggest a protective effect of DHEA on adipose tissue by upregulating PPARalpha and downregulating leptin, thereby contributing to the reduced expression of 11beta-HSD1. In summary, we provide evidence that some of the anti-diabetic effects of DHEA may be caused through inhibition of the local amplification of glucocorticoids by 11beta-HSD1 in adipose tissue.

specific bases for use of the alpha 2 blocker yohimbine

http://www.mesomorphosis.com/article...himbine-01.htm

http://www.mesomorphosis.com/article...himbine-02.htm

: Am J Physiol Endocrinol Metab. 2003 Nov;285(5):E984-90. Related Articles, Links


Aerobic training improves exercise-induced lipolysis in SCAT and lipid utilization in overweight men.

de Glisezinski I, Moro C, Pillard F, Marion-Latard F, Harant I, Meste M, Berlan M, Crampes F, Riviere D.

Unite de Recherches sur les Obesites, U586, Institut National de la Sante et de la Recherche Medicale, Institut Louis Bugnard, Centre Hospitalier Universitaire, 31403 Toulouse, France. crampes.f@chu-toulouse.fr

The aim of this study was to investigate whether endurance training improves lipid mobilization and oxidation in overweight subjects. Eleven young men (25.6 +/- 1.4 yr and body mass index 27.7 +/- 0.2) performed a 4-mo training program consisting of practicing aerobic exercise 5 days/wk. Before and after the training period, lipid oxidation was explored during a 60-min exercise at 50% of peak O2 consumption by use of indirect calorimetry. Lipid mobilization and antilipolytic alpha2-adrenoceptor effect were also studied using the microdialysis method in abdominal subcutaneous adipose tissue (SCAT). After training, plasma nonesterified fatty acid (NEFA) levels, at rest and during exercise, were significantly lower than before (P < 0.001). Lipolysis in SCAT was significantly higher after than before training. An antilipolytic alpha2-adrenoceptor effect in SCAT was underlined during exercise before training and disappeared after. The respiratory exchange ratio was lower after training, i.e., the percentage of lipid oxidation was higher only at rest. The amount of lipid oxidized was higher after training, at rest, and during exercise. Although exercise power was higher after training, the relative intensity was equivalent, as suggested by a similar increase in plasma catecholamine concentrations before and after training. In conclusion, 4-mo training in overweight men improved lipid mobilization through a decrease of antilipolytic alpha2-adrenoceptor effect in SCAT and lipid oxidation during moderate exercise. Training induced a decrease of blood NEFA, predicting better prevention of obesity.

J Clin Endocrinol Metab. 2002 Mar;87(3):1274-81. Related Articles, Links


Hypocaloric diet reduces exercise-induced alpha 2-adrenergic antilipolytic effect and alpha 2-adrenergic receptor mRNA levels in adipose tissue of obese women.

Stich V, Marion-Latard F, Hejnova J, Viguerie N, Lefort C, Suljkovicova H, Langin D, Lafontan M, Berlan M.

Department of Sport Medicine and Obesity Unit, Charles University, Prague, 10000 Czech Republic.

Previous investigations have shown that alpha 2-adrenoceptor (alpha 2-AR) stimulation blunts lipid mobilization during physiological activation of the sympathetic nervous system promoted by exercise in sc abdominal adipose tissue (SCAAT) in obese men. To investigate the effect of a low calorie diet (LCD) on the alpha 2-adrenergic responsiveness and on the expression of alpha 2-AR and beta 2-adrenoceptor (beta 2-AR) in SCAAT, 11 obese women (weight: 99.1 +/- 4.6 kg; body mass index: 34.3 +/- 1.1 kg/m(2)) received a 12-wk diet providing 500 kcal/d less than their usual diet. The exercise-induced alpha 2-adrenergic antilipolytic effect was investigated in SCAAT before and at the end of LCD. Changes in extracellular glycerol concentration and local blood flow were measured in SCAAT during a 45-min exercise bout (50% of heart rate reserve) using a control microdialysis probe and a probe supplemented with the alpha2-AR antagonist phentolamine. SCAAT biopsies were performed for determination of mRNA levels using RT-competitive PCR. Plasma catecholamine responses to exercise bout were not different before and at the end of LCD. Before LCD, the exercise-induced increase in extracellular glycerol concentration was potentiated by phentolamine supplementation, while this potentiating effect of the alpha-antagonist was not observed at the end of LCD. No changes were observed for beta 2-AR and hormone-sensitive lipase mRNA levels, while alpha 2-AR mRNA level was significantly decreased in adipose tissue during LCD. These findings show that alpha 2-AR-mediated antilipolytic action is reduced by a moderate hypocaloric diet and that down-regulation of alpha 2-AR mRNA levels may participate in the decrease of the alpha 2-adrenergic effect revealed by microdialysis.

[Kraftydog]

Is it possible to lose weight and your face is still fat? I mean there's no exercise to make the face skinner. I notice that my face has gotten a little skinnier. I was 5'10 and 265 and now I'm down to 235. However, my face is still fat. 235 is still fat for my height. Lately, Ive been taking some pictures and I have noticed it. I'm trying to up my cardio to 4-5 times a week for 45-60 minutes.

yes.