insulin causes obesity?

[coach Hale]

Insulin and obesity?

Alan Aragon and I have had this conversation a couple of times over the last week and it?s funny that all the experts that blame obesity on elevated insulin levels alone have obviously not looked at the Primary Scientific data as it indicates different. Insulin plays numerous roles in metabolism. Popular diet gurus generally have no idea of the complexity and various effects insulin cause in the body.

From Popular diets: Scientific Review Freedman et al.

Energy restriction, independent of diet composition (e.g., 15% to 73% CHO) improves glycemic control. The ability to lose weight on a calorie restricted diet over a short term period does not vary in obese healthy women as a function of insulin resistance or hyperinsulinemia. Golay et al. reported subjects consuming isocaloric diets (1000 kcal) containing 15% CHO had significantly lower insulin levels as compared with those consuming 45% CHO, yet there was no difference in weight loss between the two groups.

Grey and Kipnis studied 10 obese patients who were fed hypocaloric (1500 kcal/d) liquid-formula diets containing either 72% or 0% CHO for 4 weeks before switching to the other diet. A significant reduction in basal plasma insulin levels was noted when subjects ingested the hypo caloric formula devoid of CHO. Refeeding the hypocaloric, high CHO formula resulted in a marked increase in the basal plasma insulin. However, patients lost 0.75 to 2.0 kg/wk irrespective of caloric distribution.

The role of insulin in the synthesis and storage of fat has obscured its important effects in the central nervous system, where it acts to prevent weight gain, and has led to the misconception that insulin causes obesity. It has recently been shown that selective genetic disruption of insulin signaling in the brain leads to increased food intake and obesity in animals demonstrating that intact insulin signaling in the central nervous system is required for normal body weight regulation.

In my new book I do an extensive key point review of this paper

It should also be noted that hyper insulin sensitivity has been identified as a powerful predictor of weight gain

Also as pointed out above effects on the CNS include reduced food intake as Leptin levels increase (energy expenditure increases, energy intake decreases)

Study be Schwartz Reduced Insulin Secretion: an independent predictor of bdwt gain
Concluded IR (insulin resistance)and Hyerinsulinemia were not causal factors of obesity

Tons and tons of research challenges the catch all-phrase ?high insulin levels cause obesity?

What about ASP powerful stimulator triglyceride?


Look at the Primary Research Data it is interesting and challenges the much perpetuated information concerning insulin

thanks
Coach Hale
www.maxcondition.com