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  1. #1
    Registered User everlastinggaze's Avatar
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    Estrogen blocker or aromatase inhibitor? Rebound effect

    Which one is least likely to causes a rebound effect? I've done a lot of research here but can't get a clear picture on this one.
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    Registered User kevin9870's Avatar
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    i have read that a lot of people have had promising effects with 6oxo. I just ordered Rebound XT because a lot of people are all amped off of that. Check those out. but if you really want an anti-estrogen, go with nolvadex.
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    Registered User everlastinggaze's Avatar
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    You have to be careful with 6-OXO, I've used it twice and rebound effects each time.
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  4. #4
    Education + Dedication uhockey's Avatar
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    Utilize a tapering dose of any anti-E or SERM to minimze estrogen rebound effects. Taper up and Taper down if using as a stand alone, start high and taper down if using as PCT. Pretty simple.

    Shameless plug, I'd recommend Designer Supplements Rebound XT.
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  5. #5
    ‏‏‏‏‏‏‏‏‏‏‏‏‏‏‏‏‏‏‏‏ ‏‏‏‏ factotum's Avatar
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    Originally Posted by uhockey
    Utilize a tapering dose of any anti-E or SERM to minimze estrogen rebound effects. Taper up and Taper down if using as a stand alone, start high and taper down if using as PCT. Pretty simple.

    Shameless plug, I'd recommend Designer Supplements Rebound XT.
    Why would you need to taper up when using it as a standalone? If we were to run a two month cycle of activate and atd what would the appropriate dosing be?
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    Registered User SteakNEggs's Avatar
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    Correct me if I'm wrong uhockey (rare but it happens), I believe Rebound is a steroidal AI so no chance of rebounding.

    BTW where the F*ck is my 2 replacement bottles of Rebound? ahem....please
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  7. #7
    Education + Dedication uhockey's Avatar
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    Originally Posted by SteakNEggs
    Correct me if I'm wrong uhockey (rare but it happens), I believe Rebound is a steroidal AI so no chance of rebounding.

    BTW where the F*ck is my 2 replacement bottles of Rebound? ahem....please
    I'd guess on "in the mail," but since I am not a member of the US postal service I cannot be sure.

    Regarding a steroidal AI, think about it, theoretically you are lowering endogenous conversion to estrogen and thereby increasing testosterone. The body's natural reaction to this is to upregulate aromatase production because it WANTS estrogen. If you immediately drop off the AI, you will have excessive aromatase in your system and thereby have an increased (albeit unlikely) chance of increased aromatization of test to est. I'm not talking a huge taper here, but I'd say 1cap a day for the last 5 days would be a good idea.
    My place in here at bb.com is as a fitness enthusiast and recommendations do not represent medical advice. Please consult your examining physician for all medical concerns.

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  8. #8
    Intellectual RepubCarrier's Avatar
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    Originally Posted by uhockey
    I'd guess on "in the mail," but since I am not a member of the US postal service I cannot be sure.

    Regarding a steroidal AI, think about it, theoretically you are lowering endogenous conversion to estrogen and thereby increasing testosterone. The body's natural reaction to this is to upregulate aromatase production because it WANTS estrogen. If you immediately drop off the AI, you will have excessive aromatase in your system and thereby have an increased (albeit unlikely) chance of increased aromatization of test to est. I'm not talking a huge taper here, but I'd say 1cap a day for the last 5 days would be a good idea.
    Do you have any studies related to aromatase production that indicate 5 days is an appropriate taper length?
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  9. #9
    Education + Dedication uhockey's Avatar
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    Originally Posted by RepubCarrier
    Do you have any studies related to aromatase production that indicate 5 days is an appropriate taper length?
    No, I don't, and I presented it as a hypothetical to rebuff SteakNEggs "rarely" wrong suggestion that 0 days taper was a good idea. I personally ran the product at 2caps for 5 days, 3 caps for 12 days, 2 caps for 4 days, 1 cap for 6days for safety, but then again I'm a worrywart.
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  10. #10
    Registered User gstlynx's Avatar
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    Originally Posted by uhockey
    I'd guess on "in the mail," but since I am not a member of the US postal service I cannot be sure.

    Regarding a steroidal AI, think about it, theoretically you are lowering endogenous conversion to estrogen and thereby increasing testosterone. The body's natural reaction to this is to upregulate aromatase production because it WANTS estrogen. If you immediately drop off the AI, you will have excessive aromatase in your system and thereby have an increased (albeit unlikely) chance of increased aromatization of test to est. I'm not talking a huge taper here, but I'd say 1cap a day for the last 5 days would be a good idea.
    So by this logic, tapering up will essentially give you more est and test, not just test, thus increasing risk estrogenic sides, ie. bitch tits.

    I say start high, taper down.
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  11. #11
    Education + Dedication uhockey's Avatar
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    Originally Posted by gstlynx
    So by this logic, tapering up will essentially give you more est and test, not just test, thus increasing risk estrogenic sides, ie. bitch tits.

    I say start high, taper down.
    I only tapered up because it was my first time using the compound and I wanted to be 100% certain of tolerance in terms of joint ache and such as I've had my knee scoped in the past. Next time I would start high and taper down from there.
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  12. #12
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    Originally Posted by uhockey
    No, I don't, and I presented it as a hypothetical to rebuff SteakNEggs "rarely" wrong suggestion that 0 days taper was a good idea. I personally ran the product at 2caps for 5 days, 3 caps for 12 days, 2 caps for 4 days, 1 cap for 6days for safety, but then again I'm a worrywart.
    I was genuinely curious. I was actually thinking a longer taper might be necessary, as if I recall correctly, a few people noted estrogen rebound issues (itchy nipples) while tapering down with 1 week tapers. I imagine the measures one needs to take are largely idiosyncratic, based on sensitivity to estrogen and rate of aromatase production/HPTA sensitivity. Any studies relating to any of this would be interesting/helpful... anybody?
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  13. #13
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    Originally Posted by uhockey
    If you immediately drop off the AI, you will have excessive aromatase in your system and thereby have an increased (albeit unlikely) chance of increased aromatization of test to est.
    You might want to talk with Dr.D about this then since his recommendations about the need to taper Rebound are different from yours. Here is a link

    http://anabolicminds.com/forum/showt...hlight=rebound
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    There is likely to be some rebound effect with either one. As uhockey stated, the body "wants" a certain level of estrogen. When you lower estrogen, the body will try to compensate -- either by upregulating aromatase production, upregulating estrogen receptors, or upregulating 17-bet hydroxysteroid dehydrogenase which will convert circulating estrone and estrone sulfate (long-lived circulating estrognes) to estradiol. The best option is probably a SERm like clomid or nolvadex since they are partial agonists and provide some small amount of estrogenic stimulation.
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