Can taking too much melatonin make u hung over?

**aceman0920** · 07-03-2005, 02:05 PM

5-6 grams

**E.Bikas** · 07-03-2005, 02:17 PM

I don't think that is will make you hung over like drinking but you may be really tired or sleep way too long and generally make you feel like crap when you do wake up also your body may be achy all over

someone with a more percise answer will hopfully chime in

Eric

**aceman0920** · 07-03-2005, 02:34 PM

that's exactly what happened to me last night dude...I took 6 grams, feel asleep @ 2, and woke up about 4,000 times, and @ 5:30 PM, I made myself get out of bed...i'm in pain all over

**Outside backer** · 07-03-2005, 03:28 PM

y did u wake up 4000 times

doesnt taking it supposed to help you sleep?

**timeserved** · 07-03-2005, 03:40 PM

2.5 mg is enuff for deep sleep. Like most things in life, more is not necessarily better.

**neuron** · 07-03-2005, 03:51 PM

Originally Posted by aceman0920

5-6 grams

Thats the dumbest thing I've ever heard.

The RA for phase shifting is in the MICROGRAM ranges. Taking that much will 1) synthetise you to its affects 2) negatively feedback and shut down your natural melatonin levels in the pineal among other things.

**bubba g** · 07-03-2005, 03:55 PM

Originally Posted by triathelete04

Thats the dumbest thing I've ever heard.

The RA for phase shifting is in the MICROGRAM ranges. Taking that much will 1) synthetise you to its affects 2) negatively feedback and shut down your natural melatonin levels in the pineal among other things.

I think he means mg and not grams.. atleast I hope so.

When I take melatonin I wake up feeling groggy...

**freakie** · 07-03-2005, 03:59 PM

Oh my God! I misread your post the first time I read it. You really took 5-6 grams of melatonin? Not 5-6 milligrams?
Crap man, I'm no doctor but it seems like you could induce some kind of psychotic episode at that level. You might really screw yourself up.

I really hope you meant milligrams. Usually the tablets are 3 mg so you'd have to take 2000 tablets to get 6 grams!
If you did take that much I'd consider myself lucky that I woke up at all and never, ever do that again if I were you.

**platnm** · 07-03-2005, 04:04 PM

Where can I get this? I need it once school starts. (In a fken month

)

**bubba g** · 07-03-2005, 04:05 PM

Originally Posted by ozaer

Where can I get this? I need it once school starts. (In a fken month

)

http://www.bodybuilding.com/store/index.html

**dtrain13** · 07-03-2005, 04:06 PM

Originally Posted by freakie

Oh my God! I misread your post the first time I read it. You really took 5-6 grams of melatonin? Not 5-6 milligrams?
Crap man, I'm no doctor but it seems like you could induce some kind of psychotic episode at that level. You might really screw yourself up.

I really hope you meant milligrams. Usually the tablets are 3 mg so you'd have to take 2000 tablets to get 6 grams!
If you did take that much I'd consider myself lucky that I woke up at all and never, ever do that again if I were you.

I hope he ment mg's because if he took that much he should be lucky he isn't dead. LOL

**neuron** · 07-03-2005, 04:14 PM

I ran across this interesting study whilst investigating melatonin overdose:

Melatonin increases anagen hair rate in women with androgenetic alopecia or diffuse alopecia: results of a pilot randomized controlled trial.

Fischer TW, Burmeister G, Schmidt HW, Elsner P.

Department of Dermatology and Allergology, Friedrich-Schiller-University, Erfurter Strasse 35, D-07740 Jena, Germany. tobias.fischer@derma.uni-jena.de

BACKGROUND: In addition to the well-known hormonal influences of testosterone and dihydrotestosterone on the hair cycle, melatonin has been reported to have a beneficial effect on hair growth in animals. The effect of melatonin on hair growth in humans has not been investigated so far. OBJECTIVES: To examine whether topically applied melatonin influences anagen and telogen hair rate in women with androgenetic or diffuse hair loss. METHODS: A double-blind, randomized, placebo-controlled study was conducted in 40 women suffering from diffuse alopecia or androgenetic alopecia. A 0.1% melatonin or a placebo solution was applied on the scalp once daily for 6 months and trichograms were performed to assess anagen and telogen hair rate. To monitor effects of treatment on physiological melatonin levels, blood samples were taken over the whole study period. RESULTS: Melatonin led to a significantly increased anagen hair rate in occipital hair in women with androgenetic hair loss compared with placebo (n=12; P=0.012). For frontal hair, melatonin gave a significant increase in the group with diffuse alopecia (n=28; P=0.046). The occipital hair samples of patients with diffuse alopecia and the frontal hair counts of those with androgenetic alopecia also showed an increase of anagen hair, but differences were not significant. Plasma melatonin levels increased under treatment with melatonin, but did not exceed the physiological night peak. CONCLUSIONS: To the authors' knowledge, this pilot study is the first to show that topically applied melatonin might influence hair growth in humans in vivo. The mode of action is not known, but the effect might result from an induction of anagen phase.

Publication Types:
Clinical Trial
Randomized Controlled Trial

http://www.ncbi.nlm.nih.gov/entrez/q...07&query_hl=32

**neuron** · 07-03-2005, 04:17 PM

I think the guy temporarily neutered himself:

The effects of treatment with melatonin on the ultrastructure of mouse Leydig cells: a quantitative study.

Redins CA, Redins GM, Novaes JC.

Departamento de Morfologia, Centro Biomedico, Universidade Federal do Espirito Santo, CEP 29040-090, Vitoria, ES, Brazil. redins@npd.ufes.br

Both the presence of receptors for gonadal steroids in the pineal gland and in vitro observations of direct action of melatonin upon Leydig cells, inhibiting testosterone secretion, indicate a direct connection between pineal gland and gonadal function. In the present study, we used a transmission electron microscope to analyze the morphologic parameters of Leydig cells from adult Swiss outbred white mice treated with daily subcutaneous injections of 100 micrograms of melatonin (N-acetyl, 5-methoxytryptamine), during 22 consecutive days, compared with sham-control animals which had only received the melatonin vehicle. The melatonin group of mice showed a decrease in nuclear volume and fractional nuclear volume; smooth and rough endoplasmic reticulum; mitochondria; and Golgi complex. Our data also showed an increase in cytoplasmic volume, fractional cytoplasmic volume, and lysosomes in these same animals. The results suggest that melatonin, directly or indirectly, alters the ultrastructure of mouse Leydig cells and possibly influences their secretory activity by inhibiting their capacity to secrete steroids.

PMID: 12530190 [PubMed - indexed for MEDLINE]

http://www.ncbi.nlm.nih.gov/entrez/q...90&query_hl=32

**dtrain13** · 07-03-2005, 04:19 PM

Originally Posted by triathelete04

I think the guy temporarily neutered himself

**Mister_A** · 07-03-2005, 04:55 PM

I take 3mg (1 tablet).

**aceman0920** · 07-03-2005, 07:17 PM

5-6 mgs, which is still a hell of a lot...

Thread: Can taking too much melatonin make u hung over?

Thread Tools

Search Thread

Can taking too much melatonin make u hung over?

re

I meant

Bookmarks

Bookmarks

Posting Permissions