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Old 10-22-2007, 02:08 PM   #1
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Arimidex and Women

Hey Guys!

Yes, this is a question relating to women and steroids, and yes I have posted in the Women's section, however I think that I will get more answers if I post here as well:

So I have a question...

This is what I understand, and please if I am incorrect let me know!

Nolvadex- blocks estrogen from binding to the receptors, so your body would still produce estrogen but its effects would not be exerted (as much) because it is being blocked.

Arimidex- works by preventing the conversion of steroids made by the adrenal glands into estrogen- so it limits the amount of estrogen the body produces (estrogen that is created when aromatase converts testosterone into estradiole).

HOWEVER- if I am understanding this correctly, Arimidex would then have no effect on the estrogen that is produced by women's ovaries?

From Wikipedia:
Since most of the circulating estrogen is produced by the ovaries, not by conversion of androgens to estrogen, blocking the enzyme aromatase does not significantly decrease the production of estrogen. When aromatase inhibitors are used in premenopausal women, the decrease in estrogen activates the hypothalamus and pituitary axis to increase gonadotropin secretion, which in turn stimulates the ovary to increase androgen production. This counteracts the effect of the aromatase inhibitor.

Im just wondering if it makes sense then for me to be using Arimidex?

Previously I was on 30mg of Nolva per day... Pharmaceutical grade, still getting my period.

If it matters I am also running 10mg Winny, 40mg Anavar, 2IU GH per day, 75mcg T3.

Just wondering if anyone has any thoughts or can shed some light on this for me please
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Old 01-26-2008, 12:09 PM   #2
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I wouldn't bother with the adex, as the risk to benefit ratio may not look so good for women. You need the estrogen to be normal.

I've used it alone and actually seen slight results, but that is because I am a man, and it slightly increased my testosterone.

I know a ton about endocrinology, but obviously men and women are quite a bit different. If I were you, I'd consult a doctor that has used adex on women and/or get bloodwork done before and after using it.
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Old 01-26-2008, 12:25 PM   #3
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we have already cleared that question up bro
adex is not effective in premenopausal women
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Old 01-26-2008, 12:34 PM   #4
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Originally Posted by Vadim Beliaev View Post
we have already cleared that question up bro
adex is not effective in premenopausal women
X2. dont do it OP.
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Old 01-26-2008, 04:51 PM   #5
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i would suggest you stick to blocking agents as aromatase inhibitors will have little effect on you.

nolvadex is fairly tissue specific, i'd look into the actions of some of the next gen serms and try to find one that has a more general effect.

masteron may also be of interest to you.
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Old 01-26-2008, 05:04 PM   #6
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Well, fulvestrant (faslodex) would be the most effective since it is both non selective and a pure blocker, unlike nolvadex which still has some weak estrogen like effects.
However its price and availability is prohibitive.
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