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  1. #1
    Registered User tranceaddict's Avatar
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    Question I have elevated liver enzymes (AST / ALT)? bad?

    i got my blood results today and found elevated AST and ALT results..

    does anyone know what these enzymes do and if this is bad?

    i am trying to do my research on google

    Aspartate transaminase (AST) also called Serum Glutamic Oxaloacetic Transaminase (SGOT) or aspartate aminotransferase (ASAT) is similar to ALT in that it is another enzyme associated with liver parenchymal cells. It is raised in acute liver damage, but is also present in red cells, and cardiac and skeletal muscle and is therefore not specific to the liver. The ratio of AST to ALT is sometimes useful in differentiating between causes of liver damage.

    Alanine transaminase (ALT), also called Serum Glutamic Pyruvate Transaminase (SGPT) or Alanine aminotransferase (ALAT) is an enzyme present in hepatocytes (liver cells). When a cell is damaged, it leaks this enzyme into the blood, where it is measured. ALT rises dramatically in acute liver damage, such as viral hepatitis or paracetamol (acetaminophen) overdose. Elevations are often measured in multiples of the upper limit of normal (ULN).
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  2. #2
    HeatherAC Fan Club. MAXMUSCLE86's Avatar
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    Ask your doctor
    Recahrge: vazquez
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  3. #3
    Anchor Baby vazquez's Avatar
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    bump for uhockey
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  4. #4
    Registered User tranceaddict's Avatar
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    Originally Posted by vazquez View Post
    bump for uhockey
    cheers..

    had a look on google,,, could be related to fatty liver??
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  5. #5
    Registered User tranceaddict's Avatar
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    http://www.aafp.org/afp/20050315/1105.html

    Common Agents That Can Cause Liver Transaminase Elevations

    Medications


    Herbal supplements/vitamins

    Acetaminophen


    Chaparral leaf

    Amiodarone (Cordarone)


    Ephedra

    Amoxicillin- clavulanic acid


    Gentian

    Carbamazepine (Tegretol)


    Germander

    Fluconazole (Diflucan)


    Jin bu huan

    Glyburide (Micronase)


    Kava

    Heparin


    Scutellaria (skullcap)

    Isoniazid (INH)


    Senna

    Ketoconazole (Nizoral)


    Shark cartilage

    Labetalol (Normodyne)


    Vitamin A

    Nitrofurantoin (Furadantin)


    Nonsteroidal anti-inflammatory drugs


    Phenytoin (Dilantin)

    Protease inhibitors

    Sulfonamides

    Trazodone (Desyrel)
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  6. #6
    Registered User tranceaddict's Avatar
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    bump
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  7. #7
    Registered User v4lu3s's Avatar
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    it means your liver is being stressed by something. best bet is get with your doctor.
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  8. #8
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    From LEF:

    Hepatobiliary
    Abnormal levels of protein/albumin/globulin, albumin/globulin ratio, bilirubin, alkaline phosphatase, lactic dehydrogenase (LDH), AST (SGOT), ALT (SGPT), iron, cholesterol, and cholesterol lipoproteins are indications of potential liver/biliary problems. These may include liver damage induced by alcohol or drug use, liver cancer, or obstruction of the bile duct, among others. Together, ALT and AST allow for differential diagnosis of disorders associated with the hepatobiliary system and the pancreas. High levels of alkaline phosphatase may also indicate abnormally high levels of vitamin D.

    Gamma glutamyl transpeptidase (GGT)
    GGT is a biliary enzyme that is useful for diagnosing diseases of the liver and pancreas. It may also be used to distinguish abstinent alcoholics from alcoholics who continue to drink. Levels are commonly elevated in patients with liver inflammation (due to viral hepatitis, alcohol abuse, mononucleosis, cytomegalovirus/ CMV, myocardial infarction, diabetes mellitus, neurologic disease, trauma, and sepsis) or obstruction of the bile ducts (from pancreatic disease, gallstones, or tumors). Decreased levels of GGT may be found in hypothyroid patients or in patients with low magnesium levels or hypothalamic malfunction. GGT is a very specific indicator of liver damage or biliary obstruction, and will be the first hepatobiliary marker to indicate any increases in the blood. GGT, CEA, and alkaline phosphatase, used together, are useful markers to detect liver metastasis from the breast and colon. GGT should be tested along with AST and ALT to diagnose liver and biliary dysfunction.
    How to review your blood test results
    BLOOD TEST NORMAL VALUES
    How to interpret your blood test results
    YANA: Interpreting the Results of Your Blood Tests

    Hope that helps,
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  9. #9
    Banned 40-Yard Dash_2's Avatar
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    Originally Posted by vazquez View Post
    bump for uhockey
    Uhockey is the type of MD I would trust my life with, but I don't think he is going to give advice over the net. Go see your doctor.
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