Yohimbe HCL vs. Yohimbine what is the difference between the two drugs? Does one work better than the other?
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Thread: Yohimbe HCL vs. Yohimbine
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05-11-2002, 03:51 AM #1
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05-11-2002, 05:13 AM #2
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05-12-2002, 12:39 PM #3
Yohimbine vs. yohimbe
Quite a bit of confusion seems to exist about the difference between Yohimbine and yohimbe. Yohimbine is the principal alkaloid from the herb P. yohimbe. However, there are 31 other yohimbane alkaloids that can be present in herbal yohimbe preparations. Some of these have different and unknown selectivities and potencies (and thus, effects) at the adrenergic receptors (8, 9) -- in addition, these preparations vary greatly from brand to brand and even from batch to batch, as no standardization for extraction exists. In fact, a recent investigation found that most over the counter preparations have little to no actual yohimbine (10). And, even in the more potent preparations, most people find a higher degree of undesirable effects with the herb vs. pure Yohimbine (due to the afore mentioned 31 other yohimbane alkaloids that can be present). With Avant Lab's Yohimbine Hydrochloride, you are guaranteed 2.5mg of pure, pharmaceutical grade Yohimbine HCl per capsule, without the added side effects from other alkaloids - thus, allowing safer, more reliable dosing.
8.. Ruffolo RR, Bondinell W, Hieble JP. a - and b -Adrenoceptors: From the gene to the clinic. 2. Structure-activity relationships and therapeutic applications. J Med Chem 1995; 38(19):3415-3444.
9. Goldberg MR Robertson D. Yohimbine: a pharmacological probe for study of the a 2-adrenoceptor. Pharmacol Rev 1983;35:143-180.
10. Betz, JM, White KD. Gas chromatographic determination of yohimbine in commercial yohimbine products. J AOAC Int. 1995; 78:1189-1194.El Jefe et Patron
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05-12-2002, 12:42 PM #4
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05-12-2002, 01:44 PM #5Originally posted by andy1
par, how well does lipdoerm do against puffy nipples? Yohimburn states its about 50% of people who use it for puffy nipples will get good results, the other 50% well no results. How effective is lipoderm for this area?
thanks
But, I would certainly expect it to be considerably more effective than Yohimburn.El Jefe et Patron
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01-25-2010, 07:05 PM #6
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01-25-2010, 07:26 PM #7
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01-25-2010, 08:16 PM #8
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01-26-2010, 03:57 AM #9
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01-26-2010, 04:01 AM #10
Par's article is excellent and considered the standard when referencing this topic.
I've only used one oral, full spectrum Yohimbe that didn't feel "dirty". So, if looking to go oral I'd investigate the Yohimbe HCL. At least there you know what alkaloid is present.
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01-26-2010, 04:13 AM #11
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10-29-2012, 07:52 AM #12
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