According to Patrick Arnold in his article on 6-OXO at his ergopharm website: "6-OXO™ is what is known as a suicide inhibitor of aromatase. This means that 6-OXO™ binds to the aromatase enzyme in a permanent and irreversible manner, rendering it inactive. The result of this is an eventual diminishment of aromatase enzyme in the body and a concomitant reduction in estrogen levels. A corresponding increase in testosterone production is usually experienced as well."
--DC
========
Source:
Oregon Health & Science University
Date: 2004-03-09
Biology Behind Homosexuality In Sheep, Study Confirms
PORTLAND, Ore. _ Researchers in the Oregon Health & Science University
School of Medicine have confirmed that a male sheep's preference for
same-sex partners has biological underpinnings.
A study published in the February issue of the journal Endocrinology
demonstrates that not only are certain groups of cells different between
genders in a part of the sheep brain controlling sexual behavior, but
brain anatomy and hormone production may determine whether adult rams
prefer other rams over ewes.
"This particular study, along with others, strongly suggests that sexual
preference is biologically determined in animals, and possibly in
humans," said the study's lead author, Charles E. Roselli, Ph.D.,
professor in the Department of Physiology and Pharmacology, OHSU School
of Medicine. "The hope is that the study of these brain differences will
provide clues to the processes involved in the development and
regulation of heterosexual, as well as homosexual, behavior."
The results lend credence to previous studies in humans that described
anatomical differences between the brains of heterosexual men and
homosexual men, as well as sexually unique versions of the same cluster
of brain cells in males and females.
"Same-sex attraction is widespread across many different species." said
Roselli, whose laboratory collaborated with the Department of Animal
Sciences at Oregon State University and the USDA Agricultural Research
Service's U.S. Sheep Experiment Station in Dubois, Idaho.
Kay Larkin, Ph.D., an OHSU electron microscopist who performed
laboratory analysis for the study, said scientists now have a marker
that points to whether a ram may prefer other rams over ewes.
"There's a difference in the brain that is correlated with partner
preference rather than gender of the animal you're looking at," she
said.
About 8 percent of domestic rams display preferences for other males as
sexual partners. Scientists don't believe it's related to dominance or
flock hierarchy; rather, their typical motor pattern for intercourse is
merely directed at rams instead of ewes.
"They're one of the few species that have been systematically studied,
so we're able to do very careful and controlled experiments on sheep,"
Roselli said. "We used rams that had consistently shown exclusive sexual
preference for other rams when they were given a choice between rams and
ewes."
The study examined 27 adult, 4-year-old sheep of mixed Western breeds
reared at the U.S. Sheep Experiment Station. They included eight male
sheep exhibiting a female mate preference _ female-oriented rams _ nine
male-oriented rams and 10 ewes.
OHSU researchers discovered an irregularly shaped, densely packed
cluster of nerve cells in the hypothalamus of the sheep brain, which
they named the ovine sexually dimorphic nucleus or oSDN because it is a
different size in rams than in ewes. The hypothalamus is the part of the
brain that controls metabolic activities and reproductive functions.
The oSDN in rams that preferred females was "significantly" larger and
contained more neurons than in male-oriented rams and ewes. In addition,
the oSDN of the female-oriented rams expressed higher levels of
aromatase, a substance that converts testosterone to estradiol so the
androgen hormone can facilitate typical male sexual behaviors. Aromatase
expression was no different between male-oriented rams and ewes.
The study was the first to demonstrate an association between natural
variations in sexual partner preferences and brain structure in nonhuman
animals.
The Endocrinology study is part of a five-year, OHSU-led effort funded
through 2008 by the National Center for Research Resources, a component
of the National Institutes of Health. Scientists will work to further
characterize the rams' behavior and study when during development these
differences arise. "We do have some evidence the nucleus is sexually
dimorphic in late gestation," Roselli said.
They would also like to know whether sexual preferences can be altered
by manipulating the prenatal hormone environment, such as by using drugs
to prevent the actions of androgen in the fetal sheep brain.
In collaboration with geneticists at UCLA, Roselli has begun to study
possible differences in gene expression between brains of male-oriented
and female-oriented rams.
http://www.sciencedaily.com/releases...0309073256.htm
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Closed Thread
Results 1 to 12 of 12
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04-05-2004, 05:48 PM #1
6-OXO will make you gay. (scientific proof)
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04-05-2004, 06:08 PM #2
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04-05-2004, 06:22 PM #3
I hope that you are joking and not retarded, or illiterate for that matter. The gays had more aromatase, so you figure INHIBITING aromatase will make you gay?
WWJD-Nuff said!
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04-05-2004, 06:31 PM #4Originally posted by SupplementFreak
I hope that you are joking and not retarded, or illiterate for that matter. The gays had more aromatase, so you figure INHIBITING aromatase will make you gay?
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04-05-2004, 06:33 PM #5
- Join Date: Jul 2003
- Location: california golden coast
- Posts: 4,953
- Rep Power: 900
I guess he means that 6-oxo will make you straight ! or he doesn't know how to read correctly
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04-05-2004, 06:54 PM #6
makes you wonder about people these days
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04-05-2004, 06:58 PM #7
Watch all the "I will have no gay son!" father types start spiking their son's orange juice in the morning with 6-OXO.
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04-05-2004, 07:06 PM #8
Don't mean to disrespect anyone, but I laughed out loud when I read that.
In training...
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04-05-2004, 07:09 PM #9
- Join Date: Mar 2004
- Location: pinckneyville, il
- Age: 35
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notice all the studies were doen on sheep..ok, yea, sheep humans, hmm, i can see all the resemblance
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04-05-2004, 07:21 PM #10
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04-05-2004, 07:23 PM #11
- Join Date: Dec 2003
- Location: Dallas/Arlington TX
- Age: 38
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i don't know if you were serious, but I mean no offense. That has nothing to do with 6oxo making people gay, other than it involving the same kind of "biological tool" in the body.
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04-05-2004, 07:31 PM #12Originally posted by SupplementFreak
I hope that you are joking and not retarded, or illiterate for that matter. The gays had more aromatase, so you figure INHIBITING aromatase will make you gay?
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