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  1. #1
    in10city stalker Madevilz's Avatar
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    You should not take Beta-alanine with other aminos?

    So I was reading that magazine (Muscle News) that I received with my BB.com order, and I saw this:

    Don't take BA at the same time as other amino acids or proteins, as aminos compete for uptake. Take it at least an hour before a meal or protein supplement.
    Is this true?... Ive been taking BA with my postworkout meal for a while, I hope its not
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    Platinum Member eldawg's Avatar
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    There have been discussions that Beta Alanine and L-Taurine may compete for absoption when taken together, but I have never heard of all aminos/protein doing the same.
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    in10city stalker Madevilz's Avatar
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    bump
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    ^My Boss & I^ pmtaf's Avatar
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    I haven't heard about "all amino's" either. I know Scivation has Vasoxplode and they state to drink 30 minutes before workout and during your workout be drinking Xtend. I wouldn't think the Vasox would be out of your system by then. I don't think they would have your take vasox and then right after take xtend if it wasn't good for you.
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    Originally Posted by pmtaf View Post
    I haven't heard about "all amino's" either. I know Scivation has Vasoxplode and they state to drink 30 minutes before workout and during your workout be drinking Xtend. I wouldn't think the Vasox would be out of your system by then. I don't think they would have your take vasox and then right after take xtend if it wasn't good for you.
    maybe they dont know that themselves
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    nevigsawkufelgnisaton in10city's Avatar
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    Originally Posted by Madevilz View Post
    So I was reading that magazine (Muscle News) that I received with my BB.com order, and I saw this:



    Is this true?... Ive been taking BA with my postworkout meal for a while, I hope its not
    As mentioned, L-Taurine is the only amino so far that has implicated in absorption competition - hence the reasoning for that current recommendation (since both would contain L-Taurine).

    On the flip side, there are also indications that improved uptake can be accomplished in the same way creatine uptake is improved - insulin. Would it be enough to offset ???

    Even if you do decide to keep the post-workout dose, you still have at least 1-3 other dosing times to comsume BA without food.
    Last edited by in10city; 04-17-2007 at 01:54 AM.
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    in10city stalker Madevilz's Avatar
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    Here's an answer I got from Athletic Edge Nutrition

    It's of NO significance, don't worry about it.

    There have actually been performance studies in humans using chicken broth, which contains Beta-Alanine and of course the other amino acids, compared to the equivalent amount of Free form Beta-Alanine. The researcher took muscle biopsies at the end of the study to measure/compare CARN concentrations in the muscle.

    The result, almost identical CARN concentrations from the chicken broth compared to the Free form Beta-Alanine.

    Amino acid competition issues, are usually when you are trying to get amino's through the blood brain barrier into the brain to effect neurological function. We care about boosting CARN in the muscles.
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    Registered Bro triplewhammy's Avatar
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    Time to stock up on chicken broth!!!


    j/k


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    *MusclePharm Rep* dirtydean12's Avatar
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    doesn't B-Alanine inhibit taurine uptake?
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    There are two recent studies with "chicken breast extract," hehe.
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    in10city stalker Madevilz's Avatar
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    Originally Posted by dirtydean12 View Post
    doesn't B-Alanine inhibit taurine uptake?
    another answer from AEN

    There are two potential issue with Beta-Alanine and taurine.

    1. Decreased Beta-Alanine uptake due to them both sharing the same transporter, which in tern would decrease BA's ability to increase CARN concentrations.
    2. Taurine loss, as many people jump all over a few animal studies.

    Anyway, here are the answers:


    The supposed taurine competition issue is also NOT an issue, as clearly stated by the pioneer of Beta-Alanine research Dr.Harris. He states in his most recent study that the increase in muscle CARN with B-Alanine supplementation did not appear to be reduced by the presence of taurine. If you do not believe his word on Beta-Alanine, I don't know what to tell you, as he is THE worlds authority on Beta-Alanine research related to exercise performance. Regardless, I will be going into more detail on this subject likely later this week.

    The rat studies that showed beta-alanine decreased the taurine content in the myocardium by half in, were using doses that are over 100 times higher than the highest Beta-alanine studies of 6.4 grams a day. These rat studies aren't even relevant to how we use Beta-Alanine in terms of dosage.


    The taurine loss in the performance beta-alanine studies is insignificant and I personally don't see any additional supplementation needed, especially with the amount of protein the majority of us are supplementing on here with.

    Dr.Tallon who you may have seen debating in our faq thread, put it into context quite nicely, when he said a glass of milk would replace the amount of taurine loss shown in the beta-alanine studies. He has his PhD in carnosine metabolism, so I give his comments quite a bit of credibility
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    *MusclePharm Rep* dirtydean12's Avatar
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    Originally Posted by Madevilz View Post
    another answer from AEN
    good stuff man, that clears things up
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  13. #13
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    Post

    Originally Posted by dirtydean12 View Post
    doesn't B-Alanine inhibit taurine uptake?
    To answer your question regarding Taurine and BA interfering with eachother, the answer is NO..


    See below study, but before you read it, I want to let you know that many of the early human studies done on BA where done with EAS's phos****en Elite which contains a gram of taurine. In theory there could be absorption problems taking the two together due to them sharing similair transport mechanisms, but in reality it dosn't pan out to any level of significance in effecting BA's performance benefits.

    We looked at this very closely before recommending taking IntraXCell with SteelEdge.



    1: Amino Acids. 2006 Jul 28; [Epub ahead of print]Influence of beta-alanine supplementation on skeletal muscle carnosine concentrations and high intensity cycling capacity.
    Hill CA, Harris RC, Kim HJ, Harris BD, Sale C, Boobis LH, Kim CK, Wise JA.
    School of Sports, Exercise & Health Sciences, University of Chichester, Chichester, U.K..

    Muscle carnosine synthesis is limited by the availability of beta-alanine. Thirteen male subjects were supplemented with beta-alanine (CarnoSyntrade mark) for 4 wks, 8 of these for 10 wks. A biopsy of the vastus lateralis was obtained from 6 of the 8 at 0, 4 and 10 wks. Subjects undertook a cycle capacity test to determine total work done (TWD) at 110% (CCT(110%)) of their maximum power (W(max)). Twelve matched subjects received a placebo. Eleven of these completed the CCT(110%) at 0 and 4 wks, and 8, 10 wks. Muscle biopsies were obtained from 5 of the 8 and one additional subject. Muscle carnosine was significantly increased by +58.8% and +80.1% after 4 and 10 wks beta-alanine supplementation. Carnosine, initially 1.71 times higher in type IIa fibres, increased equally in both type I and IIa fibres. No increase was seen in control subjects. Taurine was unchanged by 10 wks of supplementation. 4 wks beta-alanine supplementation resulted in a significant increase in TWD (+13.0%); with a further +3.2% increase at 10 wks. TWD was unchanged at 4 and 10 wks in the control subjects. The increase in TWD with supplementation followed the increase in muscle carnosine.
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    www.crexcel.net dtrain13's Avatar
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    Originally Posted by dirtydean12 View Post
    good stuff man, that clears things up
    Indeed.
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    www.crexcel.net dtrain13's Avatar
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    Originally Posted by skircus7 View Post
    To answer your question regarding Taurine and BA interfering with eachother, the answer is NO..


    See below study, but before you read it, I want to let you know that many of the early human studies done on BA where done with EAS's phos****en Elite which contains a gram of taurine. In theory there could be absorption problems taking the two together due to them sharing similair transport mechanisms, but in reality it dosn't pan out to any level of significance in effecting BA's performance benefits.

    We looked at this very closely before recommending taking IntraXCell with SteelEdge.



    1: Amino Acids. 2006 Jul 28; [Epub ahead of print]Influence of beta-alanine supplementation on skeletal muscle carnosine concentrations and high intensity cycling capacity.
    Hill CA, Harris RC, Kim HJ, Harris BD, Sale C, Boobis LH, Kim CK, Wise JA.
    School of Sports, Exercise & Health Sciences, University of Chichester, Chichester, U.K..

    Muscle carnosine synthesis is limited by the availability of beta-alanine. Thirteen male subjects were supplemented with beta-alanine (CarnoSyntrade mark) for 4 wks, 8 of these for 10 wks. A biopsy of the vastus lateralis was obtained from 6 of the 8 at 0, 4 and 10 wks. Subjects undertook a cycle capacity test to determine total work done (TWD) at 110% (CCT(110%)) of their maximum power (W(max)). Twelve matched subjects received a placebo. Eleven of these completed the CCT(110%) at 0 and 4 wks, and 8, 10 wks. Muscle biopsies were obtained from 5 of the 8 and one additional subject. Muscle carnosine was significantly increased by +58.8% and +80.1% after 4 and 10 wks beta-alanine supplementation. Carnosine, initially 1.71 times higher in type IIa fibres, increased equally in both type I and IIa fibres. No increase was seen in control subjects. Taurine was unchanged by 10 wks of supplementation. 4 wks beta-alanine supplementation resulted in a significant increase in TWD (+13.0%); with a further +3.2% increase at 10 wks. TWD was unchanged at 4 and 10 wks in the control subjects. The increase in TWD with supplementation followed the increase in muscle carnosine.
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