Agmatine � More than a Pump Supplement

[kbayne]

Berberine, hell, even narala. Agmatine adds literally zero subjective difference. Yes, I know what studies say, I just don't think it pans out in real life.

Neither of them are selective to muscle tissue.

Both are great for insulin sensitivity and reducing blood glucose though.

[TheFugitive]

http://press.endocrine.org/doi/pdf/10.1210/jc.2007-2404

[XCriticalBenchX]

It would be interesting to see how some ingredients with touted GDA effects measure up via blood glucose monitoring

I test my sugar all the time with GDAs.. glucometers are like $20 at walmart lol.. why not have one. All I will say is, the cheap formulas seem to produce far better results than these expensive complex formulas that have buttloads of gda ingredients. I wont name brands but it is pretty shocking. My suggestion is buy one yourself before investing in $30 gdas. You'll be very surprised, at least I was with how my body responds to it. I usually test my sugar,

-Right before taking my gda
-30 mins later, right before my first bite
-1 hour post meal
-2 hour post meal

Agmatine at 1g does work for me at least.. I will say that. I use the I-Force brand for obvious reasons.

Mike

[aaronuconn]

I test my sugar all the time with GDAs.. glucometers are like $20 at walmart lol.. why not have one. All I will say is, the cheap formulas seem to produce far better results than these expensive complex formulas that have buttloads of gda ingredients. I wont name brands but it is pretty shocking. My suggestion is buy one yourself before investing in $30 gdas. You'll be very surprised, at least I was with how my body responds to it. I usually test my sugar,

-Right before taking my gda
-30 mins later, right before my first bite
-1 hour post meal
-2 hour post meal

Agmatine at 1g does work for me at least.. I will say that. I use the I-Force brand for obvious reasons.

Mike

Any additional dosages used? I've liked doing 1g in the AM and 1g in the PM. Never tried anything higher than that, though.

[aaronuconn]

http://press.endocrine.org/doi/pdf/10.1210/jc.2007-2404

Berberine is interesting, as it appears to be as potent as some pharmaceuticals. Research (for obvious reasons) tends to be in individuals with diabetes or some type of metabolic syndrome.

A lot of its actions are due to its impact on AMPk. I'd like to see literature on how this impacts healthy individuals

[kpeaceoutbye]

I mean, if you have the extra cash, throwing it in pre-workouts will just give you a pump and not help performance so if that is what you wanna do that's cool.
On the other hand, taking it split between am/pm carb meals, I feel like the effects are so miniscule with nutrient partitioning that it's not worth the trouble to time it before meals and worry about that. Plus, it tastes terrible raw powder form so you need to mix it.

That is just my 2 cents.

[kbayne]

I test my sugar all the time with GDAs.. glucometers are like $20 at walmart lol.. why not have one. All I will say is, the cheap formulas seem to produce far better results than these expensive complex formulas that have buttloads of gda ingredients. I wont name brands but it is pretty shocking. My suggestion is buy one yourself before investing in $30 gdas. You'll be very surprised, at least I was with how my body responds to it. I usually test my sugar,

-Right before taking my gda
-30 mins later, right before my first bite
-1 hour post meal
-2 hour post meal

Agmatine at 1g does work for me at least.. I will say that. I use the I-Force brand for obvious reasons.

Mike

I think I'm going to do some testing for myself on a few ingredients and combos just to see what happens.

Berberine is interesting, as it appears to be as potent as some pharmaceuticals. Research (for obvious reasons) tends to be in individuals with diabetes or some type of metabolic syndrome.

A lot of its actions are due to its impact on AMPk. I'd like to see literature on how this impacts healthy individuals

Berberine is a favorite of mine if used in the right situation.

[Gym God]

Berberine is interesting, as it appears to be as potent as some pharmaceuticals. Research (for obvious reasons) tends to be in individuals with diabetes or some type of metabolic syndrome.

A lot of its actions are due to its impact on AMPk. I'd like to see literature on how this impacts healthy individuals

So much this....

[neuron]

Berberine is interesting, as it appears to be as potent as some pharmaceuticals. Research (for obvious reasons) tends to be in individuals with diabetes or some type of metabolic syndrome.

A lot of its actions are due to its impact on AMPk. I'd like to see literature on how this impacts healthy individuals

It has decades of literature behind it. Metformin was developed to mimick its beneficial effects and minimize the negative effects of berberine.

Berberine is an anti-androgen through several pathways.

[neuron]

So much this....

It has had multiple human trials over the last 20-30 years.

[neuron]

For me, not single thing is felt using agmatine

Me either

[Gym God]

It has had multiple human trials over the last 20-30 years.

For berberine? I'm thinking I may be blind as nothing has stood out for me. I know I've seen many but I don't recall anything worth noting on healthy individuals? I'll have another look.

[fatboystick]

Nice write-up brother....

Good thread...

[aaronuconn]

It has decades of literature behind it. Metformin was developed to mimick its beneficial effects and minimize the negative effects of berberine.

Berberine is an anti-androgen through several pathways.

I'll re-look. I thought that most of what I saw for Berberine literature showing reductions in HbA1c and blood glucose were conducted on individuals with type 2 diabetes

[XCriticalBenchX]

Any additional dosages used? I've liked doing 1g in the AM and 1g in the PM. Never tried anything higher than that, though.

Nah.. ive never dosed higher than 1g. I typically do 1g prior to my pre-workout meal which is my first meal of the day. That is how I test all GDAs, I eat the same meal whenever testing to compare.

Mike

[aaronuconn]

Nah.. ive never dosed higher than 1g. I typically do 1g prior to my pre-workout meal which is my first meal of the day. That is how I test all GDAs, I eat the same meal whenever testing to compare.

Mike

Exactly how you'd have to do it. Do meals prior to this one vary, or is your pre-workout meal the first of the day?

[eatyourspinach]

Any thoughts on this in regards to agmatine and the liver? http://www.ncbi.nlm.nih.gov/pubmed/15028569

[DinoT1985]

Due to it's painkiller benefits, it's now banned in the UK.

[aaronuconn]

Any thoughts on this in regards to agmatine and the liver? http://www.ncbi.nlm.nih.gov/pubmed/15028569

Well, they removed 2/3 of the rats liver.

Take a look at post 7: http://forum.bodybuilding.com/showthread.php?t=3004091

[Gym God]

Well, they removed 2/3 of the rats liver.

Take a look at post 7: http://forum.bodybuilding.com/showthread.php?t=3004091

That was a nice trip down memory lane.

[eatyourspinach]

Well, they removed 2/3 of the rats liver.

Take a look at post 7: http://forum.bodybuilding.com/showthread.php?t=3004091

Pardon my ninja'ing.

[aaronuconn]

That was a nice trip down memory lane.

lol, yep. dinoiii was one of the first people, from what I remember, to speak at lengths about Agmatine

http://www.bodybuilding.com/fun/jrod17.htm

One of the interesting points was Agmatine as a nootropic. I was trying to include this in my write up, however I wasn't confident that it was much of one

[XCriticalBenchX]

Exactly how you'd have to do it. Do meals prior to this one vary, or is your pre-workout meal the first of the day?

I have a screwy schedule, but during the week I wake around noon. I eat my first meal around 2pm which is when I do testing. I do not drink anything other than water in that window of waking and eating, but that is typical for me. The meal I eat before bed anyways is always 100% consistent of 2 scoops isolate, 1tbsp mct oil, 1 cup liquid egg, 4oz chicken, 7 days of the week so that isnt a variable.

Something I have found, the more expensive, the more complex a gda is, the worse it works. The more basic formulas with less ingredients work far superior for my body at least. Slintensity by evomuse tested very well, as did anabolic pump. Some of the popular complex ones did shiat for me at least. Bitter Melon Extract does well also.

Mike

[aaronuconn]

I have a screwy schedule, but during the week I wake around noon. I eat my first meal around 2pm which is when I do testing. I do not drink anything other than water in that window of waking and eating, but that is typical for me. The meal I eat before bed anyways is always 100% consistent of 2 scoops isolate, 1tbsp mct oil, 1 cup liquid egg, 4oz chicken, 7 days of the week so that isnt a variable.

Something I have found, the more expensive, the more complex a gda is, the worse it works. The more basic formulas with less ingredients work far superior for my body at least. Slintensity by evomuse tested very well, as did anabolic pump. Some of the popular complex ones did shiat for me at least. Bitter Melon Extract does well also.

Mike

There's a product with Agamtine, Na-R-ALA, Berberine, Banaba and 4-hydroxisoleucine. One of, if not the best on the market. Interested how well it'd work for you

[kbayne]

There's a product with Agamtine, Na-R-ALA, Berberine, Banaba and 4-hydroxisoleucine. One of, if not the best on the market. Interested how well it'd work for you

Would be interesting to see how that product worked on a glucose monitor. All ingredients have good data behind them.

I think I know which product you're speaking of as well.

[fahdalsheheata]

Any thoughts on this in regards to agmatine and the liver? http://www.ncbi.nlm.nih.gov/pubmed/15028569

I'm not sure if I'm reading this right? But does it say it could cause liver disease? Someone enlighten my stupid ass

[aaronuconn]

I'm not sure if I'm reading this right? But does it say it could cause liver disease? Someone enlighten my stupid ass

Well, they removed 2/3 of the rats liver.

Take a look at post 7: http://forum.bodybuilding.com/showthread.php?t=3004091

See above

[XCriticalBenchX]

There's a product with Agamtine, Na-R-ALA, Berberine, Banaba and 4-hydroxisoleucine. One of, if not the best on the market. Interested how well it'd work for you

What product is this?

Mike

[kbayne]

What product is this?

Mike

performax labs slinmax.

If you ever end up trying it, I would love to hear your results via glucose monitoring if you mess around with it.

[XCriticalBenchX]

performax labs slinmax.

If you ever end up trying it, I would love to hear your results via glucose monitoring if you mess around with it.

Will do.. I'll let you no if I try it.

Mike