I have been reading about this morning. I am wondering if any products has this as one of the ingredients. It sounds like it would compliment some type of thermo/energy product or maybe a preworkout bcaa formula.
Supposedly it increased energy, focus and sleep patterns. This would be great in a fat-loss product b/c it does this without any stimulatory effect.
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Thread: Sulbutiamine
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09-24-2003, 08:19 AM #1
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Sulbutiamine
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09-24-2003, 10:56 AM #2
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02-25-2006, 09:43 AM #3
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02-25-2006, 11:39 AM #4
same stuff in biotest spike i believe.
Ive used the raw powder aswell. It def. does something, you have to try it out to get your own experience from it. Ive noticed strong effects from it, strong energy boost, concentration, more intensity in gym. Kind of like your a machine.Motivation/Dedication/Time=Results
-"Command And Conquer" -
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02-25-2006, 11:40 AM #5
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02-25-2006, 11:43 AM #6
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02-25-2006, 11:44 AM #7
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02-25-2006, 11:44 AM #8
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02-25-2006, 11:45 AM #9
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02-25-2006, 11:45 AM #10
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02-26-2006, 03:20 AM #11
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02-26-2006, 06:51 AM #12
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03-18-2006, 11:46 PM #13
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03-18-2006, 11:49 PM #14
Some info that MIGHT be helpful:
Sulbutiamine is rapidly absorbed and the blood concentration is maximum in 1-2 hrs after oral administration. The molecule is rapidly distributed in the whole body and is eliminated with a biological half-life of 5 hrs.
Sulbutiamine crosses the blood brain barrier more easily than vitamin B1 because of its lipophilic properties. It leads to an increased formation of thiamine triphosphate (TTP) that acts as a regulator of the synaptic transmission of many neurotransmission systems.
Sulbutiamine is a thiamine derivative which has two different properties in comparison with vitamin B1 as a result of structural modification of free thiamine, namely opening of the thiazole ring, esterification of the alcohol groups and dimerization, with formation of a disulfide bridge.Clinical efficacy of the drug enerion (sulbutiamine) in the treatment of patients with psychogenic (functional) erectile dysfunction
Dmitriev DG, Gamidov SI, Permiakova OV.
(1) Urologiia. 2005 Jan-Feb;(1):32-5.
Twenty patients with psychogenic erectile dysfunction received the drug enerion (Hungary) (sulbutiamine). After a 30-day course of enerion erectile function improved in 16 of the above patients. A mean value of the international index of erectile function (IIEF) increased in them from 17.5 to 24.8 points. Improvement of cavernous arterial blood flow after the treatment was seen in 3 of 6 patients with arterial disorders. As shown by electromyographic examinations, cavernous electric activity normalized in 8 patients. Thus, psychogenic erectile dysfunction can be effectively treated with enerion (sulbutiamine)."Free agent
Research and Development Consultant
11+ Years Experience
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03-19-2006, 01:17 AM #15
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03-19-2006, 01:55 AM #16
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... and a little more... (some overlap of pu12en12g's)
Sulbutiamine is described as a centrally acting cholinergic agent like donepezil which is used for Parkinson's and Alzheimer symptoms. These drugs inhibit the destruction of acetylcholine (a stimulating neurotransmittor) in the brain. Increased concentrations of acetylcholine are believed to be responsible for greater alertness, memory and acuity.
Sulbutiamine is an ACE inhibitor, which results in greater brain acetylcholine concentrations which would increase concentration, memory, alertness, etc.Pharmaceutical grade, pure sulbutiamine
Sulbutiamine has been shown to facilitate wakefulness, improve long-term memory, speed up reaction time, decrease anxiety and increase overall resistance to stress.
The effect can be described as a boost in mood, almost euphoric in some cases, comparable to a very strong coffee without the agitation and anxiety sometimes associated with caffeine. The duration tends to last the day, as opposed to caffeine which provides a short boost followed by let-down.
As a form of B-vitamin (thiamine), it is water soluble and excess is eliminated in the urine.
Popular with athletes and those involved with physical competition. Same active ingredient as in the drug Arcalion.
Sulbutiamine is rapidly absorbed and the blood concentration is maximum in 1-2 hrs after oral administration. The molecule is rapidly distributed in the whole body and is eliminated with a biological half-life of 5 hrs.
New research showing support for erectile dysfunction (1)
Third party testing posted in approx 2 weeks.
Supplement Facts:
120 capsules, 200 mg.
Serving Size: 1 capsule.
Servings per container: 120
Sulbutiamine 200 mg *
*daily value not established
Other ingredients: maltodextrin, gelatin (capsule). Store tightly in a cool dry area. Keep out of reach of children. Do not use if safety seal is broken or damaged.
Suggesed dose: Take 1-2 capsules per day, always with breakfast or an AM meal. Do not exceed 3 capsules at any time as this may cause severe headaches.
Excessive doses may cause agitation or tremors.
Pregnant or breast feeding women should not use this product.
Sulbutiamine crosses the blood brain barrier more easily than vitamin B1 because of its lipophilic properties. It leads to an increased formation of thiamine triphosphate (TTP) that acts as a regulator of the synaptic transmission of many neurotransmission systems.
Sulbutiamine is a thiamine derivative which has two different properties in comparison with vitamin B1 as a result of structural modification of free thiamine, namely opening of the thiazole ring, esterification of the alcohol groups and dimerization, with formation of a disulfide bridge.
(1) Urologiia. 2005 Jan-Feb;(1):32-5.
[Clinical efficacy of the drug enerion (sulbutiamine) in the treatment of patients with psychogenic (functional) erectile dysfunction]
Dmitriev DG, Gamidov SI, Permiakova OV.
Twenty patients with psychogenic erectile dysfunction received the drug enerion (Hungary) (sulbutiamine). After a 30-day course of enerion erectile function improved in 16 of the above patients. A mean value of the international index of erectile function (IIEF) increased in them from 17.5 to 24.8 points. Improvement of cavernous arterial blood flow after the treatment was seen in 3 of 6 patients with arterial disorders. As shown by electromyographic examinations, cavernous electric activity normalized in 8 patients. Thus, psychogenic erectile dysfunction can be effectively treated with enerion (sulbutiamine)."Last edited by in10city; 03-19-2006 at 01:57 AM.
It is the mark of an educated mind to be able to entertain a thought without accepting it.
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03-19-2006, 02:27 AM #17
- Join Date: Oct 2005
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Thiamine and its Salts
http://www.inchem.org/documents/pims/pharm/pimg015.htm
Acetiamine Hydrochloride (r INNM)
Acethiamine Hydrochloride
Diacethiamine Hydrochloride
Benfotiamine (r INN)
S-Benzoylthiamine O-Monophosphate
Bisbentiamine (r INN)
O-Benzoylthiamine Disulphide
Bisbutiamine
O-Butyrylthiamine Disulphide
Cetotiamine Hydrochloride (r INNM)
Dicethiam Hydrochloride
Cycotiamine (r INN)
CCT
Cyclorcabolthiamine
Fursultiamine (r INN)
Thiamine Tetrahydrofurfuryl Disulphide
TTFD
Octotiamine (r INN)
TATD
Thioctothiamine
Prosultiamine (r INN)
DTPT
Thiamine Propyl Disulphide
Sulbutiamine (r INN)
Bisibutiamine
O-Isobutyrylthiamine Disulphide
Thiamine Hydrochloride (BANM, INNM)
Aneurine Hydrochloride
Thiamin Hydrochloride
Thiamine Chloride
Thiamini Hydrochloridum
Thiaminii Chloridum
Vitamin B1
Thiamine Nitrate (BANM, INNM)
Aneurine Mononitrate
Thiamine Mononitrate
Vitamin B1 MononitrateIt is the mark of an educated mind to be able to entertain a thought without accepting it.
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03-19-2006, 02:36 AM #18
Just some pricing info.. street price appears to be around $.50 to $1.00 per gram, with a recommended dose of 200-500mg and a TERRIBLE TASTE.. much worse than CEE.
As always, please see disclaimer below.Last edited by pu12en12g; 03-19-2006 at 02:38 AM.
Free agent
Research and Development Consultant
11+ Years Experience
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03-19-2006, 03:00 AM #19What is the function of vitamin B1?
Energy Production
Most cells in the body depend on sugar as an energy source. When oxygen is used to help convert sugar into usable energy, the process of energy generation is called aerobic energy production. This process cannot take place without adequate supplies of vitamin B1, since B1 is part of an enzyme system (called the pyruvate dehydrogenase system) that enables oxygen-based processing of sugar.
When vitamin B1 functions in this energy-production capacity, it is usually present in the form of TDP, or thiamin diphosphate. Other forms of vitamin B1, including TPP (thiamin pyrophosphate) and TMP (thiamin monophosphate) are also important in energy production.
Because vitamin B1 is so important in energy production, and because food energy is usually measured in terms of calories, vitamin B1 is often prescribed in relationship to caloric intake. For example, recommendations sometime suggest intake of 0.5 milligrams of B1 for every 1,000 calories consumed.
Nervous System Support
Vitamin B1 also plays a key role in support of the nervous system, where it permits healthy development of the fat-like coverings which surround most nerves (called myelin sheaths). In the absence of vitamin B1, these coverings can degenerate or become damaged. Pain, prickly sensations, and nerve deadening are nerve-related symptoms that can result from vitamin B1 deficiency.
A second type of connection between vitamin B1 and the nervous system involves its role in the production of the messaging molecule acetylcholine. This molecule, called a neurotransmitter, is used by the nervous system to relay messages between the nerves and muscles. Acetylcholine cannot be produced without adequate supplies of vitamin B1. Because acetylcholine is used by the nervous system to ensure proper muscle tone in the heart, deficiency of B1 can also result in compromised heart function.Free agent
Research and Development Consultant
11+ Years Experience
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11-25-2006, 11:05 AM #20
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11-26-2006, 03:27 PM #21
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11-26-2006, 03:41 PM #22
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11-26-2006, 03:44 PM #23
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11-26-2006, 03:51 PM #24
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11-26-2006, 05:24 PM #25
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11-26-2006, 05:29 PM #26
Interesting development from Patrick Arnold:
Quote:
Originally Posted by Patrick Arnold
stim x does not contain geranamine. it has geranium oil extract on the label but i tested it and there is no geranamine in there
the active ingredient in stimx is a subutiramine (sp) derivative
___________
Maybe you did not understand me the first time. thats funny because PA just ordered our X-force to test it also because it contains geranime too, now do you understand..LOLAll posts made by IBELabs are for purely entertainment purposes and do not reflect the actions of the person or company responsible for this name.
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11-26-2006, 05:49 PM #27
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11-26-2006, 06:34 PM #28
I opted to use allothiamine/allithiamine in SizeOn tabs. Allothiamine is one of the few thiamine nootropic analogs that is DSHEA compliant as it is found in garlic while most if not all of the others are synthetic.
Boom!
Originally Posted by Med Sci Monit. 2004 Sep;10(9):RA199-203
I do not think any of these sulfated thiamine analogs really do a heck of a lot for "muscles" but more for "perception" - see below:
Originally Posted by Int J Sport Nutr. 1997 Mar;7(1):39-47.
BK
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11-26-2006, 06:41 PM #29
Biotest has this in Spike I think. I'm not really all that impressed with any of them as they end up giving me a headache. Some info that you might like to see about Sulbutiamine, good and bad.
Originally Posted by World J Biol Psychiatry. 2006;7(3):183-5.
Originally Posted by Pharmacol Biochem Behav. 1985 Aug;23(2):195-8.
Originally Posted by Drugs Today (Barc). 1999 Mar;35(3):187-92.
BK
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11-26-2006, 07:24 PM #30
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