Brachial artery flow-mediated dilatation studies may indicate keto diet not so health

[Looton]

*****://www.youtube.com/watch?v=8BQcm3A6twQ
Low carbohydrate diets - Professor Jon Buckley - Knowledge Works

This lecture broaches the subject at about 21:30.
The professor alerts his audience to the emerging risk factor *Brachial artery flow-mediated dilatation* due to low-fat high-carb diets.


http://www.ncbi.nlm.nih.gov/pubmed/9388088
CONCLUSION:

A single high-fat meal transiently reduces endothelial function for up to 4 hours in healthy, normocholesterolemic subjects, probably through the accumulation of triglyceride-rich lipoproteins. This decrease is blocked by pretreatment with antioxidant vitamins C and E, suggesting an oxidative mechanism.

__________________________________________________ ____________________________________


Many studies cited at the bottom here, including at pubmed;
http://content.onlinejacc.org/articl...icleid=1127712

[XinApoK]

Thank you. This is solid stuff.

[repower]

My serious opinion about the post, it's, that you CAN'T eat "healthy", I prefer to say "eat for yours goals" (i'm not the only one that thinks that way). Being in low carb diet, low fat diet, high protein diet, I think that you've to eat for your goals and nothing more. One easy example, it's Michael Phelps: the guy was eating 12.000 calories a day, for better performance; I can clearly say that all that amount of carbs "aren't healthy", but, that works for him... and his goals.

[grndzro]

http://conditioningresearch.blogspot...r-healthy.html

[LizzieTish]

*****://www.youtube.com/watch?v=8BQcm3A6twQ
Low carbohydrate diets - Professor Jon Buckley - Knowledge Works

This lecture broaches the subject at about 21:30.
The professor alerts his audience to the emerging risk factor *Brachial artery flow-mediated dilatation* due to low-fat high-carb diets.


http://www.ncbi.nlm.nih.gov/pubmed/9388088
CONCLUSION:

A single high-fat meal transiently reduces endothelial function for up to 4 hours in healthy, normocholesterolemic subjects, probably through the accumulation of triglyceride-rich lipoproteins. This decrease is blocked by pretreatment with antioxidant vitamins C and E, suggesting an oxidative mechanism.

INTERVENTION:
Three randomly administered breakfasts: (1) a high-fat meal (3766 J [900 calories], 50 g of fat); (2) a low-fat meal (3766 J [900 calories], 0 g of fat); and (3) a high-fat meal and pretreatment with oral administration of vitamins C (1 g) and E (800 IU) (high-fat meal with vitamins). A subgroup of 10 subjects also ate the low-fat meal with the same vitamin pretreatment (low-fat meal with vitamins).

So the "high fat" meal had only 50% of the calories coming from fat. Sounds to me like the other 50% of carbs and possibly excess protein (which any excess would be broken down into glucose) is what's actually creating the oxidative mechanism. Would like to see the results with 75-85 grams of fat. 50% of calories from fat isn't a "high fat" diet.