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Thread: Amentoflavone

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    Amentoflavone

    For purposes of muscular strength (increase in Ca2+ release from the sarcoplasmic reticulum), is acute dosing before training more practical, or does ED dosing provide cumulative benefits that is worth the cost-benefit?
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    If it works like caffeine in releasing Ca2+ one would assume it would be most beneficial taken pwo. I have no idea how long it takes to reach full effect after a single dose, however.

    Amentoflavone, like caffeine, caused a concentration-dependent increase in Ca2+ release from the heavy fraction of fragmented sarcoplasmic reticulum of rabbit skeletal muscle. The Ca2+ -releasing activity of amentoflavone was approximately 20 times more potent than that of caffeine. The bell-shaped profile of Ca2+ dependence for amentoflavone was almost the same as that for caffeine. Typical blockers of Ca2+ -induced Ca2+ release channels, such as Mg2+, procaine and ruthenium red, inhibited markedly amentoflavone- and caffeine-induced 45Ca2+ release. The maximum 45Ca2+ release in response to amentoflavone was not changed by caffeine, but was further increased by adenosine-5'-(beta,gamma-methylene) triphosphate. This compound enhanced [3H]ryanodine binding to the heavy fraction of fragmented sarcoplasmic reticulum with a decrease in K(D) but without a change in Bmax. These results suggest that amentoflavone, which does not contain a nitrogen atom, probably binds to the caffeine-binding site in Ca2+ channels and thus potentiates Ca2+ -induced Ca2+ release from the heavy fraction of fragmented sarcoplasmic reticulum.
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    Just read Coop's breakdown over at AM. I wish he'd post cool stuff like that here.
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    Alright, amentoflavone sounds pretty amazing--why isn't it in more products?
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    Originally Posted by Nyrin View Post
    Alright, amentoflavone sounds pretty amazing--why isn't it in more products?
    It'll become more mainstream now.
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    Originally Posted by Nyrin View Post
    Alright, amentoflavone sounds pretty amazing--why isn't it in more products?

    New novel ingredients take time to catch on.



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    will be buying bulk soon. What is the dosing for it?


    Edit: Nevermind found it. 2 caps 15 min pre.
    Last edited by DasBiceps; 05-17-2014 at 05:12 PM.
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    As has been mentioned, I asked Coop last night and he suggested 2 caps, preworkout only.
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    Originally Posted by UncleWade View Post
    As has been mentioned, I asked Coop last night and he suggested 2 caps, preworkout only.
    Good deal. I'll add a cap to Katana.
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    Originally Posted by DasBiceps View Post
    will be buying bulk soon. What is the dosing for it?


    Edit: Nevermind found it. 2 caps 15 min pre.
    what mg?
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    Originally Posted by cumminslifter View Post
    what mg?
    400mg Selaginella Tamariscina @ a 20% amentoflavone extract (80mg).
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    Originally Posted by cumminslifter View Post
    what mg?
    200mg/cap at a 20% extract, IIRC.
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    Originally Posted by cumminslifter View Post
    what mg?
    1 cap:
    Selaginella Tamariscina (whole plant) Extract (20% Amentoflavone) 200 mg

    So 400mg


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    thanks fellas^
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    In this thread are the people that can say "I used amentoflavone before it was popular" when it gets added to everything like betaine is now.
    My secret? Texting between sets.
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    Originally Posted by eatyourspinach View Post
    In this thread are the people that can say "I used amentoflavone before it was popular" when it gets added to everything like betaine is now.
    true, i used betaine about 3 years back before anyone knew about it. read about it in a muscle mag. cant say i noticed much but would love to try it again
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    Originally Posted by xLGx View Post
    For purposes of muscular strength (increase in Ca2+ release from the sarcoplasmic reticulum), is acute dosing before training more practical, or does ED dosing provide cumulative benefits that is worth the cost-benefit?
    Dose it preworkout for your goals. I use it everyday but I'm also after its effects with respect to insulin and PDE (which works well with forskolin)
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    Originally Posted by Jeff the Repper View Post
    Uncut

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    App Nut is putting amentoflavone to pretty good use.
    Uncut is top notch pre-workout and i'm dying to try that Beta Test.
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    best taken pre workout on training days, but pre carb meal on an off day is also a smart move
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    Originally Posted by Jeff the Repper View Post
    Uncut

    Say thanks Dirk.
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    for strength amentoflavone everyday or just on training day ?
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    neuron used to have a great writeup of this on his blog but he took it down for whatever reason
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  25. #25
    Virus and BS Free Jeff the Repper's Avatar
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    Originally Posted by Mr.Cooper69 View Post
    Neuron was the one who brought it to the forefront, all credit goes to him. Dirk did make a good product though, I love me some uncut
    I must have missed Neuron's articles, I'll see what I can go back and find. Was there a product released prior to Uncut that got by me?
    BS and Virus free
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  26. #26
    evidence based poster Terrimonas's Avatar
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    Originally Posted by Jeff the Repper View Post
    I must have missed Neuron's articles, I'll see what I can go back and find. Was there a product released prior to Uncut that got by me?
    AN was far from the first to use it in a product. It was in NexCare's Rev-XP back in the early/mid 2000's. Even AAEFX had in it a product before AN.

    neuron's blog entry http://hightowerpharmacology.blogspo...toflavone.html
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  27. #27
    Registered User VicMackey92's Avatar
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    Hey I have just receiv my amentomax & peak beta

    A few questions :

    - Can I take amentomax & peak beta together ? 30 min pre workout for both ?
    - When I take 1 cap of Uncut ( who have amentoflavone in it ) I need to lower amentomax to one cap or I still take 2 cap ?
    - Amentomax have any problem with some ingredients ?


    thanx a lot!
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    Banned Mr.Cooper69's Avatar
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    Yes
    1 or 2 will work in that case, whereas I'd always do 2 if solo
    Nope
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    Registered User VicMackey92's Avatar
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    Originally Posted by Mr.Cooper69 View Post
    Yes
    1 or 2 will work in that case, whereas I'd always do 2 if solo
    Nope

    thanx! Can be taking with food ? I take my pre workout meal 30min before working out.
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    Originally Posted by VicMackey92 View Post
    thanx! Can be taking with food ? I take my pre workout meal 30min before working out.
    Absolutely, it is great with food or preworkout...best 2 ways to take it
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