For purposes of muscular strength (increase in Ca2+ release from the sarcoplasmic reticulum), is acute dosing before training more practical, or does ED dosing provide cumulative benefits that is worth the cost-benefit?
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Thread: Amentoflavone
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05-17-2014, 04:03 PM #1
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05-17-2014, 04:15 PM #2
If it works like caffeine in releasing Ca2+ one would assume it would be most beneficial taken pwo. I have no idea how long it takes to reach full effect after a single dose, however.
Amentoflavone, like caffeine, caused a concentration-dependent increase in Ca2+ release from the heavy fraction of fragmented sarcoplasmic reticulum of rabbit skeletal muscle. The Ca2+ -releasing activity of amentoflavone was approximately 20 times more potent than that of caffeine. The bell-shaped profile of Ca2+ dependence for amentoflavone was almost the same as that for caffeine. Typical blockers of Ca2+ -induced Ca2+ release channels, such as Mg2+, procaine and ruthenium red, inhibited markedly amentoflavone- and caffeine-induced 45Ca2+ release. The maximum 45Ca2+ release in response to amentoflavone was not changed by caffeine, but was further increased by adenosine-5'-(beta,gamma-methylene) triphosphate. This compound enhanced [3H]ryanodine binding to the heavy fraction of fragmented sarcoplasmic reticulum with a decrease in K(D) but without a change in Bmax. These results suggest that amentoflavone, which does not contain a nitrogen atom, probably binds to the caffeine-binding site in Ca2+ channels and thus potentiates Ca2+ -induced Ca2+ release from the heavy fraction of fragmented sarcoplasmic reticulum.
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05-17-2014, 04:27 PM #3
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05-17-2014, 04:44 PM #4
Alright, amentoflavone sounds pretty amazing--why isn't it in more products?
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05-17-2014, 04:47 PM #5
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05-17-2014, 04:48 PM #6
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05-17-2014, 04:57 PM #7
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05-17-2014, 06:17 PM #8
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05-17-2014, 06:43 PM #9
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05-17-2014, 06:48 PM #10
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05-17-2014, 06:50 PM #11
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05-17-2014, 06:50 PM #12
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05-17-2014, 06:52 PM #13
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05-17-2014, 07:02 PM #14
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05-17-2014, 07:08 PM #15
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05-17-2014, 08:09 PM #16
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05-17-2014, 08:37 PM #17
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05-17-2014, 08:45 PM #18
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05-17-2014, 08:46 PM #19
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05-17-2014, 09:20 PM #20
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05-17-2014, 09:44 PM #21
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05-17-2014, 10:32 PM #22
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05-18-2014, 02:18 AM #23
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05-18-2014, 02:50 AM #24
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05-18-2014, 05:21 AM #25
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05-18-2014, 06:19 AM #26
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AN was far from the first to use it in a product. It was in NexCare's Rev-XP back in the early/mid 2000's. Even AAEFX had in it a product before AN.
neuron's blog entry http://hightowerpharmacology.blogspo...toflavone.html
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06-07-2014, 03:51 AM #27
Hey I have just receiv my amentomax & peak beta
A few questions :
- Can I take amentomax & peak beta together ? 30 min pre workout for both ?
- When I take 1 cap of Uncut ( who have amentoflavone in it ) I need to lower amentomax to one cap or I still take 2 cap ?
- Amentomax have any problem with some ingredients ?
thanx a lot!
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06-07-2014, 07:24 AM #28
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06-07-2014, 07:26 AM #29
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06-07-2014, 07:35 AM #30
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