๑۩۞۩๑ Heracles ๑۩۞۩๑

[THEHUGE]

Meet The Enemy...and The Hero

Myostatin is produced primarily in skeletal muscle cells, circulates in the bloodstream and exerts its effects on muscle tissue. It inhibits muscle differentiation and development in a process known as Myogenesis.
This protein normally restrains muscle growth, ensuring that muscles do not grow too large. Mutations that reduce the production of functional myostatin lead to an overgrowth of muscle tissue. Mutations of human myostatin gene result in individuals having significantly more muscle bulk and hence are considerably
stronger than normal (sorry, it's not contagious...).
Now of course, we're NOT saying that using Heracles will make you a ripped 300 pounds freak. We're talking about a moderate gene expression modulation, not a total gene ablation like in the pictures that flood the net (you know, those showing comics-like unreal, chimeric hypermuscled dogs, mice and bulls) .
Still, it should give you an idea of the utmost importance of Myostatin in muscle growth and fat loss.
On a good note, modulating Myostatin won't turn you into a cow either.

So how do I keep in check that bad, bad Myostatin? I won't tell you to lift and follow a high protein diet. If you're reading these lines, I guess that's a given.

Some of you maybe remember the great excitement, a decade or so ago, caused by an alleged Myostatin inhibitor found in an algae (Cystoseira canariensis).
You likely also remember countless of furious users who fired their money on those (also very expensive) products.
No surprise. After ingestion, it gets totally degraded and nothing reaches the systemic circulation...hence, zero effect.

Now the amazing news.

There IS a naturally occurring Myostatin inhibitor. One with very good oral bioavailability.
A completely safe and healthy compound. Something that most of us have already (unknowingly) ingested in tiny amounts.

A compound, finally, proven to significantly inhibit Myostation and improve the Myostatin/Follistation ratio when administered orally to healthy men!

This marvellous ingredient is EPICATECHIN(do NOT confuse it with other Cocoa flavanols, ours it's a specialized custom-made extract containing 95% Epicatechin and no, no product on the market can
ever remotely come close to this).

Its effects were so striking that now Epicatechin is getting evaluated for the treatment of progressive muscle loss and impaired skeletal muscle function in Muscular Dystrophy patients.
The subjects of a very recent study were given a total of 1 mg (-)-epicatechin per kg bodyweight per day (N.B.: our product is meant for bodybuilders...hence VERY generously dosed) . The researchers then looked at the effects that the supplement had on the subjects’ hand grip strength (in case you're wondering why a handgrip test, it's a simple and commonly used test of general strength level, also very well researched) and at the concentrations of myostatin and follistatin in their blood.

Treatment for 7 days with (-)-epicatechin yielded a bilateral increase in hand strength of 7%, which was accompanied by a significant increase (49.2%) in the ratio of plasma follistatin/myostatin levels.

A 49.2% increase in the Myostatin/Follistatin ratio is astonishing. Even more so in a mere week.

So YES, we can state out loud that Heracles increases muscle anabolism through an extremely effective yet safe and legal mechanism of action.

Just a brief note: Epicatechin also stimulates LH and Testosterone synthesis and promotes a substantial increase in endothelial Nitric Oxide.


Now, as if this wasn't groundbreaking enough, we went one further step forward.

Heracles features Hesperidin Methyl Chalcone
Hsperidin is a bioflavinoid naturally found in small concentrations in the peel and pulp of citrus fruit.
While hesperidin itself is very poorly water-soluble, hesperidin methyl chalcone is highly water-soluble, allowing for greater absorption of the molecule in the gastrointestinal tract.
Getting enough Hesperidin through food to exert the effects we're going to elucidate, would be basically impossble. For example, 100 gr of grapefruit flesh contains about 3 mg hesperidin, and it's not even the methyl chalcone(more bioavailable) form.
So what does it do?
Hesperedin promotes osteoblast differentiation in human mesenchymal stem cells, indicating an anabolic effect of hesperedin on bone metabolism. Bone marrow mesenchymal stem cells undergo myogenic differentiation as well as osteogenic differentiation. The researchers therefore explored whether hesperedin modulates muscle cell differentiation.
Hesperedin promoted myogenic differentiation, in a dose-dependent manner, by increasing myogenin gene expression. MyoD-induced myogenin gene transcription was enhanced by hesperedin, as this bioflavonoid augmented the nuclear localization and myogenin promoter-binding of MyoD. In addition, hesperedin
accelerated muscle regeneration induced by muscle injury. These results got confirmed both in vitro and in vivo.
Myogenin expression was considerably augmented in the presence of hesperedin during differentiation. Myogenin expression was prominent in the nucleus, indicating that hesperedin promotes myogenic gene expression and terminal differentiation. Skeletal muscle development involves an initial period of
myoblast replication, followed by a phase in which some myoblasts continue to proliferate while others undergo terminal differentiation. The latter process involves activation of muscle-specific gene expression, and the fusion of single cells into multinucleated muscle fibers.
These results strongly demonstrate that hesperedin has a potent pro-myogenic activity via regulation of MyoD activity in the myogenic differentiation of mesenchymal stem cells. During myoblast differentiation or regeneration, MyoD is essential for skeletal muscle repair .
If there's a perfect supporting character for Epicatechin, that's Hesperidin Methyl Chalcone.

HERACLES
Coming in May 2014.
Smash through your old barriers.

[bmarchia]

Looks very interesting...

[Kon_Rock]

Interested!

[RebuildMe]

Hell... Its been worth the wait!

[alvin1]

Boom !!!!

[MrMakAttack]

Very interested in this product. Looking forward to reading some reviews and/or logs.

[Joe102687]

Definitely sound like a product worth experimenting with.

[COUNTRYMIKE]

Can't wait to use this!!!

[dbone1026]

Yawn ... old news

[JayLS1-327]

Who cares, what's the date it'll be available ?

[misfit28]

Interested to see some logs on this.

[KBoss302]

If it was any other company, I'd call BS. But having THEHUGE behind this product...my interests are peaked.

I was burned though by that 2001 myostatin scam and have never forgotten...Cytodyne Technologies, Champion Nutrition, Pinnacle and Biotest...I'm looking at you. So I'll wait for the logs on this one.

[dbone1026]

If it was any other company, I'd call BS. But having THEHUGE behind this product...my interests are peaked.

I was burned though by that 2001 myostatin scam and have never forgotten...Cytodyne Technologies, Champion Nutrition, Pinnacle and Biotest...I'm looking at you. So I'll wait for the logs on this one.

Ah yes, I remember Cytodyne, I think they actually made a Myostatin protein powder

[WOLFBBGOLD]

Ah yes, I remember Cytodyne, I think they actually made a Myostatin protein powder

Me too...Got burnt by so many Myostatin scams. Myostatin stuff is just hard to believe anymore

[KBoss302]

Ah yes, I remember Cytodyne, I think they actually made a Myostatin protein powder

Pinnacle made the protein powder.

[thelast10]

A lot of companies company out with epicatechin based products lately, been reading some logs of people using it, seems very promising!

[dbone1026]

Pinnacle made the protein powder.

Ah yes, was thinking about Cytodyne Methoxy-Pro

[THEHUGE]

Looks very interesting...

Interested!

Hell... Its been worth the wait!

Boom !!!!

Very interested in this product. Looking forward to reading some reviews and/or logs.

Definitely sound like a product worth experimenting with.

Can't wait to use this!!!

Thanks gentlemen.

Yawn ... old news

You're such an ungrateful individual

Who cares, what's the date it'll be available ?

I kindly have to decline your nudes offer this time.

If it was any other company, I'd call BS. But having THEHUGE behind this product...my interests are peaked.

Thank you, very appreciated.

Me too...Got burnt by so many Myostatin scams. Myostatin stuff is just hard to believe anymore

You're right. Luckily we finally have solid, reliable human indisputable data.

[adamci1]

subbed!

[SwolenONE]

Sweet!!

[0TheHerculator0]

Lol @ this product and my username.

[thelast10]

Was just looking at my user cp, and saw this thread and remembered the part in nutty professor when their all eating, and she goes Heracles! Heracles! Heracles!

[stevenjamesvick]

neat.

[THEHUGE]

subbed!

Sweet!!

neat.

Merci beaucoup

Lol @ this product and my username.

Then you MUST get a dozen bottles.

Was just looking at my user cp, and saw this thread and remembered the part in nutty professor when their all eating, and she goes Heracles! Heracles! Heracles!

Unforgotten masterpiece

[BogusForLife]

Was just looking at my user cp, and saw this thread and remembered the part in nutty professor when their all eating, and she goes Heracles! Heracles! Heracles!

She's calling him Hercules not Heracles but that is a very memorable scene regardless.


Interesting stuff as always Mr. Huge. Will be considering a purchase once available.

[Segansational]

A lot of companies company out with epicatechin based products lately, been reading some logs of people using it, seems very promising!

Yeah, third one I am aware of. But it certainly has gotten me interested in epicatechin...

[RoadPigJohn]

Looks like a promising new innovative product.
Defiantly would try to put my hands on it.

[dbone1026]

Defiantly would try to put my hands on it.

This would be the easiest way to get THEHUGE to send you some freebies Also, no need to be defiant

[thelast10]

She's calling him Hercules not Heracles but that is a very memorable scene regardless.


Interesting stuff as always Mr. Huge. Will be considering a purchase once available.

I was actually trying to write hercales but I gave up fighting my phones auto correct lol

Yeah, third one I am aware of. But it certainly has gotten me interested in epicatechin...

I got a bottle of another Epi product (not gonna mention it) but if any1 knows about the 2 other (that I know of besides this) Epi products, its the one with just epi in it... This is probably the most similar because I believe the 2nd ingredient is added for absorption/ph levels... I could be wrong... My bottle is on back order for a week or so, once I get it, Ill post my thoughts on Epi somewhere in this board....

[TrainerTone]

This looks interesting. Can't wait to see some reviews.